Nelma Veronica Marques
Nelma Veronica Marques
Neuroendocrinology Research Center, Endocrinology Section, Medical School and Hospital Universitário Clementino Fraga Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil
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Luiz Eduardo Armondi Wildemberg
Luiz Eduardo Armondi Wildemberg
Neuroendocrinology Research Center, Endocrinology Section, Medical School and Hospital Universitário Clementino Fraga Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil
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Monica R Gadelha
Monica R Gadelha
Neuroendocrinology Research Center, Endocrinology Section, Medical School and Hospital Universitário Clementino Fraga Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil
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dose reduction in two patients because of substantial IGF1 reduction ( 5 ). Herein, we present a retrospective analysis of a subset of patients who received long-term treatment with pasireotide, who maintained their biochemical response and had
Jothydev Kesavadev
Jothydev Kesavadev
Jothydev’s Diabetes Research Centre, Trivandrum, Kerala, India
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Pradeep Babu Sadasivan Pillai
Pradeep Babu Sadasivan Pillai
Jothydev’s Diabetes Research Centre, Trivandrum, Kerala, India
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Arun Shankar
Arun Shankar
Jothydev’s Diabetes Research Centre, Trivandrum, Kerala, India
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Gopika Krishnan
Gopika Krishnan
Jothydev’s Diabetes Research Centre, Trivandrum, Kerala, India
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Sunitha Jothydev
Sunitha Jothydev
Jothydev’s Diabetes Research Centre, Trivandrum, Kerala, India
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could be beyond glycemic reduction. Secondary effects like prevention of weight gain, reduction in insulin dose, improved cardiovascular risk profile, etc., may be expected from the addition of sitagliptin to diabetes treatment ( 7 , 8 ). Although
A Chinoy
A Chinoy
Royal Manchester Children’s Hospital, Manchester, UK
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M Skae
M Skae
Royal Manchester Children’s Hospital, Manchester, UK
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A Babiker
A Babiker
King Abdullah Specialized Children’s Hospital, Riyadh, Saudi Arabia
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D Kendall
D Kendall
Royal Preston Hospital, Preston, UK
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M Z Mughal
M Z Mughal
Royal Manchester Children’s Hospital, Manchester, UK
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R Padidela
R Padidela
Royal Manchester Children’s Hospital, Manchester, UK
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reduction in ACD doses to 200 ng (55 ng/kg) daily. Figure 2 displays his cCa during and after this illness, along with alterations in management. Figure 2 Presentation and progress of case 2 during bronchiolitis illness, demonstrating changes in
Sirazum Choudhury
Sirazum Choudhury
Endocrinology and Investigative Medicine, Department of Metabolism, Digestion and Reproduction, Imperial College London, Commonwealth Building, London, UK
Department of Endocrinology, Imperial College Healthcare NHS Trust, London, UK
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Department of Endocrinology, Imperial College Healthcare NHS Trust, London, UK
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Tricia Tan
Tricia Tan
Endocrinology and Investigative Medicine, Department of Metabolism, Digestion and Reproduction, Imperial College London, Commonwealth Building, London, UK
Department of Endocrinology, Imperial College Healthcare NHS Trust, London, UK
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Department of Endocrinology, Imperial College Healthcare NHS Trust, London, UK
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Katharine Lazarus
Katharine Lazarus
Endocrinology and Investigative Medicine, Department of Metabolism, Digestion and Reproduction, Imperial College London, Commonwealth Building, London, UK
Department of Endocrinology, Imperial College Healthcare NHS Trust, London, UK
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Department of Endocrinology, Imperial College Healthcare NHS Trust, London, UK
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Karim Meeran
Karim Meeran
Endocrinology and Investigative Medicine, Department of Metabolism, Digestion and Reproduction, Imperial College London, Commonwealth Building, London, UK
Department of Endocrinology, Imperial College Healthcare NHS Trust, London, UK
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Department of Endocrinology, Imperial College Healthcare NHS Trust, London, UK
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-daily hydrocortisone to the same total daily dose of Plenadren, administered once a day in the morning ( 38 ). Pharmacokinetic studies were performed in 18 patients. The area-under-the-curve (AUC) cortisol profile demonstrated a reduction of 19.4% in AUC 0–24 h , for
Gabriella Oliveira Lima
Gabriella Oliveira Lima
Laboratory of Pharmacology and Toxicology of Natural Products, Institute of Biological Sciences, Federal University of Pará, Belém, Pará, Brazil
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Alex Luiz Menezes da Silva
Alex Luiz Menezes da Silva
Laboratory of Pharmacology and Toxicology of Natural Products, Institute of Biological Sciences, Federal University of Pará, Belém, Pará, Brazil
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Julianne Elba Cunha Azevedo
Julianne Elba Cunha Azevedo
Laboratory of Pharmacology and Toxicology of Natural Products, Institute of Biological Sciences, Federal University of Pará, Belém, Pará, Brazil
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Chirlene Pinheiro Nascimento
Chirlene Pinheiro Nascimento
Laboratory of Pharmacology and Toxicology of Natural Products, Institute of Biological Sciences, Federal University of Pará, Belém, Pará, Brazil
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Luana Rodrigues Vieira
Luana Rodrigues Vieira
Laboratory of Pharmacology and Toxicology of Natural Products, Institute of Biological Sciences, Federal University of Pará, Belém, Pará, Brazil
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Akira Otake Hamoy
Akira Otake Hamoy
Laboratory of Pharmacology and Toxicology of Natural Products, Institute of Biological Sciences, Federal University of Pará, Belém, Pará, Brazil
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Luan Oliveira Ferreira
Luan Oliveira Ferreira
Laboratory of Experimental Neuropathology, Institute of Biological Sciences, Federal University of Pará, Belém, Pará, Brazil
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Verônica Regina Lobato Oliveira Bahia
Verônica Regina Lobato Oliveira Bahia
Multidisciplinary Laboratory of Animal Morphology, Institute of Biological Sciences, Federal University of Pará, Belém, Pará, Brazil
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Nilton Akio Muto
Nilton Akio Muto
Amazon Bioactive Compounds Valorization Center, Institute of Biological Sciences, Federal University of Pará, Belém, Pará, Brazil
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Dielly Catrina Favacho Lopes
Dielly Catrina Favacho Lopes
Laboratory of Experimental Neuropathology, Institute of Biological Sciences, Federal University of Pará, Belém, Pará, Brazil
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Moisés Hamoy
Moisés Hamoy
Laboratory of Pharmacology and Toxicology of Natural Products, Institute of Biological Sciences, Federal University of Pará, Belém, Pará, Brazil
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). According to international guidelines, recommended doses of vitamin D range from 400 to 800 IU/day and the choice of dosage is influenced by age ( 2 , 3 , 4 ). These levels are sufficient to maintain the homeostasis of physiological functions and
Josephina G Kuiper
Josephina G Kuiper
PHARMO Institute for Drug Outcomes Research, AE Utrecht, Netherlands
Department of Public Health, Erasmus University Medical Center, Rotterdam, Netherlands
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Department of Public Health, Erasmus University Medical Center, Rotterdam, Netherlands
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Aline C Fenneman
Aline C Fenneman
Department of Clinical and Experimental Vascular Medicine, Amsterdam Cardiovascular Sciences (ACS), Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands
Department of Endocrinology and Metabolism, Amsterdam Gastroenterology Endocrinology Metabolism (AGEM), Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands
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Department of Endocrinology and Metabolism, Amsterdam Gastroenterology Endocrinology Metabolism (AGEM), Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands
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Anne H van der Spek
Anne H van der Spek
Department of Endocrinology and Metabolism, Amsterdam Gastroenterology Endocrinology Metabolism (AGEM), Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands
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Elena Rampanelli
Elena Rampanelli
Department of Clinical and Experimental Vascular Medicine, Amsterdam Cardiovascular Sciences (ACS), Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands
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Max Nieuwdorp
Max Nieuwdorp
Department of Clinical and Experimental Vascular Medicine, Amsterdam Cardiovascular Sciences (ACS), Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands
Department of Endocrinology and Metabolism, Amsterdam Gastroenterology Endocrinology Metabolism (AGEM), Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands
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Department of Endocrinology and Metabolism, Amsterdam Gastroenterology Endocrinology Metabolism (AGEM), Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands
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Myrthe P P van Herk-Sukel
Myrthe P P van Herk-Sukel
Department of Internal Medicine and Dermatology, University Medical Center Utrecht, Utrecht, Netherlands
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Valery E P P Lemmens
Valery E P P Lemmens
Department of Public Health, Erasmus University Medical Center, Rotterdam, Netherlands
Netherlands Comprehensive Cancer Organisation, Utrecht, Netherlands
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Netherlands Comprehensive Cancer Organisation, Utrecht, Netherlands
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Ernst J Kuipers
Ernst J Kuipers
Department of Gastroenterology and Hepatology, Erasmus University Medical Center, Rotterdam, Netherlands
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Ron M C Herings
Ron M C Herings
PHARMO Institute for Drug Outcomes Research, AE Utrecht, Netherlands
Department of Epidemiology and Data Science, Amsterdam UMC, Amsterdam, Netherlands
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Department of Epidemiology and Data Science, Amsterdam UMC, Amsterdam, Netherlands
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Eric Fliers
Eric Fliers
Department of Endocrinology and Metabolism, Amsterdam Gastroenterology Endocrinology Metabolism (AGEM), Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands
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III (Dio3) ( 7 ), whereas increased intracellular levels of TH led to a potent reduction in the growth rate of human colorectal tumour cell lines ( 9 ). This raises the question whether levothyroxine users are protected against CRC development due to
Lili Liu
Lili Liu
Department of Metabolism & Endocrinology, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China
Key Laboratory of Diabetes Immunology, Central South University, Ministry of Education, National Clinical Research Center for Metabolic Diseases, Changsha, Hunan, China
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Key Laboratory of Diabetes Immunology, Central South University, Ministry of Education, National Clinical Research Center for Metabolic Diseases, Changsha, Hunan, China
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Zhuo Shao
Zhuo Shao
Department of General Surgery, Changhai Hospital, The Second Military Medical University, Shanghai, Shanghai, China
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Ying Xia
Ying Xia
Department of Metabolism & Endocrinology, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China
Key Laboratory of Diabetes Immunology, Central South University, Ministry of Education, National Clinical Research Center for Metabolic Diseases, Changsha, Hunan, China
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Key Laboratory of Diabetes Immunology, Central South University, Ministry of Education, National Clinical Research Center for Metabolic Diseases, Changsha, Hunan, China
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Jiabi Qin
Jiabi Qin
Department of Epidemiology & Health Statistics, Xiangya School of Public Health, Central South University, Changsha, Hunan, China
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Yang Xiao
Yang Xiao
Department of Metabolism & Endocrinology, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China
Key Laboratory of Diabetes Immunology, Central South University, Ministry of Education, National Clinical Research Center for Metabolic Diseases, Changsha, Hunan, China
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Key Laboratory of Diabetes Immunology, Central South University, Ministry of Education, National Clinical Research Center for Metabolic Diseases, Changsha, Hunan, China
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Zhiguang Zhou
Zhiguang Zhou
Department of Metabolism & Endocrinology, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China
Key Laboratory of Diabetes Immunology, Central South University, Ministry of Education, National Clinical Research Center for Metabolic Diseases, Changsha, Hunan, China
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Key Laboratory of Diabetes Immunology, Central South University, Ministry of Education, National Clinical Research Center for Metabolic Diseases, Changsha, Hunan, China
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Zubing Mei
Zubing Mei
Department of Anorectal Surgery, Shuguang Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China
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difference in the reduction in HbA1c after the incretin-based treatment (WMD 0.00, 95% CI −0.19 to 0.19, P = 0.97) ( Table 2 ). Secondary outcomes of interest Reduction in total daily insulin dose in T1DM patients with incretin-based therapy and
David S McLaren
David S McLaren
Department of Endocrinology, Leeds Centre for Diabetes & Endocrinology, Leeds Teaching Hospital NHS Trust, Leeds, UK
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Aarani Devi
Aarani Devi
Clinical Oncology, Leeds Cancer Centre, Leeds Teaching Hospital NHS Trust, Leeds, UK
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Nikolaos Kyriakakis
Nikolaos Kyriakakis
Department of Endocrinology, Leeds Centre for Diabetes & Endocrinology, Leeds Teaching Hospital NHS Trust, Leeds, UK
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Michelle Kwok-Williams
Michelle Kwok-Williams
Clinical Oncology, Leeds Cancer Centre, Leeds Teaching Hospital NHS Trust, Leeds, UK
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Robert D Murray
Robert D Murray
Department of Endocrinology, Leeds Centre for Diabetes & Endocrinology, Leeds Teaching Hospital NHS Trust, Leeds, UK
Division of Cardiovascular and Diabetes Research, Leeds Institute of Cardiovascular and Metabolic Medicine (LICAMM), University of Leeds, Leeds, UK
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Division of Cardiovascular and Diabetes Research, Leeds Institute of Cardiovascular and Metabolic Medicine (LICAMM), University of Leeds, Leeds, UK
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with lesser dose to normal tissue and the theoretical advantage of the reduction in long-term side effects leads to PBT to be considered the treatment of choice internationally. However, taking into consideration the sparsity of robust comparative
Shruti Khare
Shruti Khare
Department of Endocrinology, Seth GS Medical College and KEM Hospital, Parel, Mumbai 400012, India
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Anurag R Lila
Anurag R Lila
Department of Endocrinology, Seth GS Medical College and KEM Hospital, Parel, Mumbai 400012, India
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Hiren Patt
Hiren Patt
Department of Endocrinology, Seth GS Medical College and KEM Hospital, Parel, Mumbai 400012, India
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Chaitanya Yerawar
Chaitanya Yerawar
Department of Endocrinology, Seth GS Medical College and KEM Hospital, Parel, Mumbai 400012, India
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Manjunath Goroshi
Manjunath Goroshi
Department of Endocrinology, Seth GS Medical College and KEM Hospital, Parel, Mumbai 400012, India
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Tushar Bandgar
Tushar Bandgar
Department of Endocrinology, Seth GS Medical College and KEM Hospital, Parel, Mumbai 400012, India
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Nalini S Shah
Nalini S Shah
Department of Endocrinology, Seth GS Medical College and KEM Hospital, Parel, Mumbai 400012, India
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on serum prolactin normalisation and tumour size reduction in addition. In general cabergoline dose of 2.0 mg/week has been proposed to define resistance to treatment in macroprolactinomas, and dose escalation beyond 3.5 mg/week does not have
Zhen-yu Song
Zhen-yu Song
Department of Urology, Jinshan Hospital of Fudan University, Shanghai, China
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Qiuming Yao
Qiuming Yao
Department of Endocrinology, Jinshan Hospital of Fudan University, Shanghai, China
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Zhiyuan Zhuo
Zhiyuan Zhuo
Department of Urology, Jinshan Hospital of Fudan University, Shanghai, China
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Zhe Ma
Zhe Ma
Department of Urology, Jinshan Hospital of Fudan University, Shanghai, China
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Gang Chen
Gang Chen
Department of Urology, Jinshan Hospital of Fudan University, Shanghai, China
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explore whether circulating 25-hydroxyvitamin D level was correlated with the survival of PCa through a dose–response meta-analysis. Materials and methods Search strategy We searched PubMed and EMBASE databases from inception to July 15, 2018
