Background Pediatric differentiated thyroid carcinoma (DTC) is a rare disease, although it is the most frequent endocrine malignancy in children, representing 2–4% of all pediatric malignancies. According to the Surveillance, Epidemiology, and
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S C Clement, W E Visser, C A Lebbink, D Albano, H L Claahsen-van der Grinten, A Czarniecka, R P Dias, M P Dierselhuis, I Dzivite-Krisane, R Elisei, A Garcia-Burillo, L Izatt, C Kanaka-Gantenbein, H Krude, L Lamartina, K Lorenz, M Luster, R Navardauskaitė, M Negre Busó, K Newbold, R P Peeters, G Pellegriti, A Piccardo, A L Priego, A Redlich, L de Sanctis, M Sobrinho-Simões, A S P van Trotsenburg, F A Verburg, M Vriens, T P Links, S F Ahmed, and H M van Santen
Alexander Heinzel, Dirk Müller, Hanneke M van Santen, Sarah C Clement, Arthur B Schneider, and Frederik A Verburg
-1375678 ) 13 Thies ED Tanase K Maeder U Luster M Buck AK Hanscheid H Reiners C Verburg FA . The number of 131I therapy courses needed to achieve complete remission is an indicator of prognosis in patients with differentiated thyroid carcinoma
Simonetta Piana, Eleonora Zanetti, Alessandra Bisagni, Alessia Ciarrocchi, Davide Giordano, Federica Torricelli, Teresa Rossi, and Moira Ragazzi
mediates growth suppression by cell cycle arrest in well-differentiated thyroid carcinomas (WDTCs) ( 15 , 16 ). On the other side, NOTCH1 has been described highly expressed in WDTC with BRAF , RET /papillary thyroid carcinoma (PTC) mutation or active
Meihua Jin, Woo Kyung Lee, Mi-Hyeon You, Ahreum Jang, Sheue-yann Cheng, Won Gu Kim, Min Ji Jeon, and Yu-Mi Lee
, anaplastic thyroid carcinoma. SHMT2 is associated with de-differentiation and stemness of thyroid cancer To validate the clinical importance of the SHMT2 in human thyroid cancer, we performed a comprehensive analysis using transcriptomes and
David C Llewellyn, Rajaventhan Srirajaskanthan, Royce P Vincent, Catherine Guy, Eftychia E Drakou, Simon J B Aylwin, Ashley B Grossman, John K Ramage, and Georgios K Dimitriadis
, Napsin A, thyroglobulin and p40 was negative ( Fig. 4C ). The Ki-67 proliferation index was high at 84%. The morphology and immunophenotype were most in keeping with metastatic medullary thyroid carcinoma, although other metastatic neuroendocrine
Olav Inge Håskjold, Henrik Stenestø Foshaug, Therese Benedikte Iversen, Helga Charlotte Kjøren, and Vegard Heimly Brun
: colloid nodule, adenomatoid colloid nodule, follicular adenoma, follicular carcinoma, follicular variant of papillary thyroid carcinoma, papillary thyroid carcinoma, or other thyroid cancer. The operator also indicated the confidence of the assignment to
Tiemo S Gerber, Arno Schad, Nils Hartmann, Erik Springer, Ulrich Zechner, and Thomas J Musholt
Introduction Poorly differentiated thyroid carcinoma (PDTC) represents an aggressive variant of thyroid cancer that predominantly arises from the differentiated variants of papillary and follicular thyroid carcinoma (PTC and FTC, respectively
Luchuan Li, Baoyuan Li, Bin Lv, Weili Liang, Binbin Zhang, Qingdong Zeng, Andrew G Turner, and Lei Sheng
, all were assessed to be well-differentiated papillary thyroid carcinoma (PTC), namely 21 cases (81%) of papillary thyroid microcarcinoma (PTMC), 3 cases (12%) of conventional PTC, and 2 cases (7%) of a tall-cell variant of PTC ( Table 3 ). Bilaterality
Andrea Mazurat, Andrea Torroni, Jane Hendrickson-Rebizant, Harbinder Benning, Richard W Nason, and K Alok Pathak
Introduction Well-differentiated thyroid carcinoma (WDTC) represents a group of thyroid cancers that are associated with increasing incidence and excellent posttreatment outcome (1) . This group comprises different histological types, the most
Flávia O Valentim, Bárbara P Coelho, Hélio A Miot, Caroline Y Hayashi, Danilo T A Jaune, Cristiano C Oliveira, Mariângela E A Marques, José Vicente Tagliarini, Emanuel C Castilho, Paula Soares, and Gláucia M F S Mazeto
Introduction The differential diagnosis of thyroid follicular lesions includes both benign tumors, such as follicular adenoma (FA) and malignant tumors, such as follicular carcinoma (FC) and follicular variant of papillary carcinoma (FVPC