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Chiara Mele, Maria Teresa Samà, Alessandro Angelo Bisoffi, Marina Caputo, Valentina Bullara, Stefania Mai, Gillian Elisabeth Walker, Flavia Prodam, Paolo Marzullo, Gianluca Aimaretti and Loredana Pagano

Introduction The incidence rates of differentiated thyroid cancer (DTC) have been rising in many countries over the last few decades ( 1 , 2 ) along with a parallel increase in obesity and metabolic disorders ( 3 ). Even if the growing

Open access

Tiemo S Gerber, Arno Schad, Nils Hartmann, Erik Springer, Ulrich Zechner and Thomas J Musholt

Introduction Poorly differentiated thyroid carcinoma (PDTC) represents an aggressive variant of thyroid cancer that predominantly arises from the differentiated variants of papillary and follicular thyroid carcinoma (PTC and FTC, respectively

Open access

Susana Pastor, Abdelmounaim Akdi, Eddy R González, Juan Castell, Josefina Biarnés, Ricard Marcos and Antonia Velázquez

Introduction Thyroid cancer is of special concern in endocrinology practice, accounting for more than 90% of all endocrine cancers. Moreover, its incidence is increasing in developed countries (1, 2) . Differentiated thyroid carcinoma (DTC

Open access

Andrea Mazurat, Andrea Torroni, Jane Hendrickson-Rebizant, Harbinder Benning, Richard W Nason and K Alok Pathak

Introduction Well-differentiated thyroid carcinoma (WDTC) represents a group of thyroid cancers that are associated with increasing incidence and excellent posttreatment outcome (1) . This group comprises different histological types, the most

Open access

Erika Urbano Lima, Ileana G S Rubio, Joaquim Custodio Da Silva, Ana Luiza Galrão, Danielle Pêssoa, Taise Cerqueira Oliveira, Fabiane Carrijo, Igor Silva Campos, Luciano Fonseca Espinheira, Luiz Jose Sampaio, Claudio Rogerio Lima, Janete Maria Cerutti and Helton Estrela Ramos

Introduction Differentiated thyroid cancer (DTC) has continued to increase over the past several decades, likely due to enhanced detection ( 1 , 2 ). Cancer research, in general, has benefited greatly from many of the new scientific

Open access

Eugenie S Lim, Shanty G Shah, Mona Waterhouse, Scott Akker, William Drake, Nick Plowman, Daniel M Berney, Polly Richards, Ashok Adams, Ewa Nowosinska, Carmel Brennan and Maralyn Druce

Introduction Differentiated thyroid cancer (DTC) is the most frequently occurring endocrine cancer and its incidence has been increasing steadily in men and women over the last few decades ( 1 , 2 , 3 ). DTC includes papillary thyroid cancer

Open access

Natalie Su-Jing Yap, Richard Maher and Diana Louise Learoyd

available 1/24 1/26 FNA-Tg, thyroglobulin in needle washouts from fine-needle aspiration biopsy; DTC, differentiated thyroid carcinoma; AJCC/UICC TNM, American Joint Committee on Cancer/International Union against Cancer TNM Classification System for

Open access

C Sui, Q He, R Du, D Zhang, F Li, G Dionigi, N Liang and H Sun

dissected cervical nodes, however, a discrepancy may exist between the absolute number of positive nodes and the substantive extent of differentiated thyroid cancer (DTC) node metastasis ( 1 , 2 , 6 ). Therefore, the NR, defined as the absolute number of

Open access

Dario de Biase, Federica Torricelli, Moira Ragazzi, Benedetta Donati, Elisabetta Kuhn, Michela Visani, Giorgia Acquaviva, Annalisa Pession, Giovanni Tallini, Simonetta Piana and Alessia Ciarrocchi

die within 1 year from diagnosis. Well-differentiated papillary thyroid cancers (PTCs) are considered indolent tumors, with slow rate of growth, low metastatic potential and excellent prognosis (10-year patient survival rate up to 95%) ( 4 , 5

Open access

Simonetta Piana, Eleonora Zanetti, Alessandra Bisagni, Alessia Ciarrocchi, Davide Giordano, Federica Torricelli, Teresa Rossi and Moira Ragazzi

) and six were hyalinizing trabecular tumors (HTT). The remaining were malignant lesions. 68.1% were classical well-differentiated thyroid cancers, papillary thyroid carcinoma (PTC, n  = 48, 54.5%) and follicular thyroid carcinoma (FTC, n  = 12, 13