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Jose M Garcia GRECC VA Puget Sound HCS/University of Washington, Seattle, Washington, USA

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Beverly M K Biller Massachusetts General Hospital, Neuroendocrine Unit, Boston, Massachusetts, USA

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Márta Korbonits Barts and the London School of Medicine, Queen Mary University of London, Endocrinology, London, UK

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Vera Popovic University of Belgrade, Medical Faculty, Belgrade, Serbia

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Anton Luger Division of Endocrinology and Metabolism, Medical University, General Hospital, Vienna, Austria

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Christian J Strasburger Charité-Universitätsmedizin, Clinical Endocrinology CCM, Berlin, Germany

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Philippe Chanson Assistance Publique-Hôpitaux de Paris, Hôpital de Bicêtre, Service d’Endocrinologie et des Maladies de la Reproduction, Centre de Référence des Maladies Rares de l’Hypophyse, and Université Paris-Saclay, Univ. Paris-Sud, Inserm, Signalisation Hormonale, Physiopathologie Endocrinienne et Métabolique, Le Kremlin-Bicêtre, France

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Ronald Swerdloff The Lundquist Institute at Harbor-UCLA Medical Center, Torrance, California, USA

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Christina Wang The Lundquist Institute at Harbor-UCLA Medical Center, Torrance, California, USA

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Rosa Rosanna Fleming Strongbridge Biopharma, Trevose, Pennsylvania, USA

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Fredric Cohen Strongbridge Biopharma, Trevose, Pennsylvania, USA

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Nicola Ammer Aeterna Zentaris GmbH, Frankfurt, Hessen, Germany

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Gilbert Mueller Aeterna Zentaris GmbH, Frankfurt, Hessen, Germany

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Nicky Kelepouris Novo Nordisk Inc., Plainsboro, New Jersey, USA

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Frank Strobl Novo Nordisk Inc., Plainsboro, New Jersey, USA

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Vlady Ostrow Novo Nordisk Inc., Plainsboro, New Jersey, USA

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Kevin C J Yuen University of Arizona College of Medicine and Creighton School of Medicine, Barrow Pituitary Center, Barrow Neurological Institute, Phoenix, Arizona, USA

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, reduced cognition, lack of energy, and/or social isolation ( 12 , 13 ). Treatment of AGHD with growth hormone (GH) replacement therapy has been shown to improve many, but not all, of the clinical features of AGHD ( 14 ). However, the diagnosis of AGHD

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-20-0491
Volume/Issue:
Volume 10: Issue 1
Open access
Elena V Varlamov Department of Medicine (Endocrinology, Diabetes and Clinical Nutrition), Oregon Health & Science University, Portland, Oregon, USA
Department of Neurological Surgery, Oregon Health & Science University, Portland, Oregon, USA
Pituitary Center, Oregon Health & Science University, Portland, Oregon, USA

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Dan Alexandru Niculescu Department of Neurological Surgery, Oregon Health & Science University, Portland, Oregon, USA

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Swechya Banskota Department of Medicine (Endocrinology, Diabetes and Clinical Nutrition), Oregon Health & Science University, Portland, Oregon, USA
Department of Neurological Surgery, Oregon Health & Science University, Portland, Oregon, USA
Pituitary Center, Oregon Health & Science University, Portland, Oregon, USA

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Simona Andreea Galoiu Department of Neurological Surgery, Oregon Health & Science University, Portland, Oregon, USA

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Catalina Poiana Department of Neurological Surgery, Oregon Health & Science University, Portland, Oregon, USA

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Maria Fleseriu Department of Medicine (Endocrinology, Diabetes and Clinical Nutrition), Oregon Health & Science University, Portland, Oregon, USA
Department of Neurological Surgery, Oregon Health & Science University, Portland, Oregon, USA
Pituitary Center, Oregon Health & Science University, Portland, Oregon, USA

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secondary diabetes mellitus (DM)) ( 2 , 3 , 4 ). Long-standing acromegaly is relatively easy to diagnose due to multiple pathognomonic signs and symptoms. However, milder disease cases pose a great challenge, and an acromegaly diagnosis is eventually

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-21-0035
Volume/Issue:
Volume 10: Issue 7
Open access
Kevin C J Yuen Departments of Neuroendocrinology and Neurosurgery, Barrow Neurological Institute, University of Arizona College of Medicine and Creighton School of Medicine, Phoenix, Arizona, United States

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Gudmundur Johannsson Department of Endocrinology, Sahlgrenska University Hospital and Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden

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Ken K Y Ho The Garvan Institute of Medical Research and the Faculty of Medicine, University of New South Wales, Sydney, Australia

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Bradley S Miller Pediatric Endocrinology, University of Minnesota Medical School, M Health Fairview Masonic Children’s Hospital, Minneapolis, Minnesota, United States

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Ignacio Bergada Centro de Investigaciones Endocrinológicas "Dr César Bergadá" (CEDIE), CONICET-FEI-División de Endocrinología, Hospital de Niños Ricardo Gutiérrez, Buenos Aires, Argentina

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Alan D Rogol Pediatric Diabetes and Endocrinology, University of Virginia, Charlottesville, Virginia, United States

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GHD to severe GH resistance ( 8 ). Thus, establishing the diagnosis of GHD can be challenging in children and adults. Although short stature and growth faltering are useful clinical markers for GHD in children, signs and symptoms of adult subjects with

Article Type:
Review Article
Collections:
Pituitary and Hypothalamus
DOI:
https://doi.org/10.1530/EC-22-0504
Volume/Issue:
Volume 12: Issue 7
Open access
Filippo Ceccato Endocrinology Unit, Department of Medicine DIMED, University-Hospital of Padova, Padova, Italy
Department of Neuroscience DNS, University of Padova, Padova, Italy

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Diego Cecchin Department of Neuroscience DNS, University of Padova, Padova, Italy
Nuclear Medicine Unit, Department of Medicine – DIMED, University-Hospital of Padova, Padova, Italy
Padova Neuroscience Center PNC, University of Padova, Padova, Italy

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Michele Gregianin Nuclear Medicine Unit, Castelfranco Veneto, Italy

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Giacomo Ricci Department of Neuroscience DNS, University of Padova, Padova, Italy

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Cristina Campi Padova Neuroscience Center PNC, University of Padova, Padova, Italy
Department of Mathematics ‘Tullio Levi-Civita’ DM, University of Padova, Padova, Italy

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Filippo Crimì Radiology Unit, Department of Medicine DIMED, University-Hospital of Padova, Padova, Italy

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Marta Bergamo Endocrinology Unit, Department of Medicine DIMED, University-Hospital of Padova, Padova, Italy

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Annibale Versari Nuclear Medicine Unit, Reggio Emilia, Italy

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Carmelo Lacognata Radiology Department, University-Hospital of Padova, Padova, Italy

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Federico Rea Thoracic Surgery Unit, Department of Cardiac, Thoracic and Vascular Sciences, University Hospital of Padova, Padova, Italy

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Mattia Barbot Endocrinology Unit, Department of Medicine DIMED, University-Hospital of Padova, Padova, Italy

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Carla Scaroni Endocrinology Unit, Department of Medicine DIMED, University-Hospital of Padova, Padova, Italy

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defined overt when the ACTH-secreting neoplasm is promptly identified soon after diagnosis of hypercortisolism, covert when the tumour is discovered during a subsequent evaluation or a prolonged follow-up and occult when the ACTH source cannot be detected

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-20-0089
Volume/Issue:
Volume 9: Issue 4
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Kristine Zøylner Swan Department of Otorhinolaryngology Head & Neck Surgery, Aarhus University Hospital, Aarhus N, Denmark
Department of Clinical Medicine, Health, Aarhus University, Aarhus N, Denmark

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Steen Joop Bonnema Department of Endocrinology, Odense University Hospital, Odense C, Denmark

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Marie Louise Jespersen Department of Pathology, Aarhus University Hospital, Aarhus N, Denmark

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Viveque Egsgaard Nielsen Department of Clinical Medicine, Health, Aarhus University, Aarhus N, Denmark

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.gov (NCT02150772). Table 1 Cytological results for nodules. BSRTC Distribution, n (%) Malignancy rate, % Histological diagnosis No FNAB 69 (17) 3 1 PTC, 1 met BSRTC 1 50 (12) 14 7 PTC BSRTC 2 90

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-19-0324
Volume/Issue:
Volume 8: Issue 8
Open access
Yanfei Chen Department of Pediatrics, The First Affiliated Hospital of Guangxi Medical University, Nanning, China

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Mei Li Department of Pediatrics, The First Affiliated Hospital of Guangxi Medical University, Nanning, China

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Binrong Liao Department of Pediatrics, The First Affiliated Hospital of Guangxi Medical University, Nanning, China

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Jingzi Zhong Department of Pediatrics, The First Affiliated Hospital of Guangxi Medical University, Nanning, China

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Dan Lan Department of Pediatrics, The First Affiliated Hospital of Guangxi Medical University, Nanning, China

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, insulin-like growth factor-1 (IGF-1), insulin) have shown potential roles in the diagnosis of CPP ( 10 , 11 , 12 ). Recently, Kutlu et al. ( 13 ) reported the role of another novel adipomyokine, irisin, in the diagnosis of CPP, and their study implied

Article Type:
Research Article
Collections:
Reproduction
DOI:
https://doi.org/10.1530/EC-22-0028
Volume/Issue:
Volume 11: Issue 4
Open access
Dongyan Han Department of Pathology, Shanghai Tenth People’s Hospital, Tongji University School of Medicine, Shanghai, China

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Min Ding Department of General Surgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China

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Rongli Xie Department of General Surgery, RuiJin Hospital Lu Wan Branch, Shanghai Jiaotong University School of Medicine, Shanghai, China

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Zhengshi Wang Thyroid Center, Shanghai Tenth People’s Hospital, Tongji University School of Medicine, Shanghai, China
Shanghai Center of Thyroid Diseases, Shanghai Tenth People’s Hospital, Tongji University School of Medicine, Shanghai, China

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Guohui Xiao Department of General Surgery, Pancreatic Disease Center, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China

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Xiaohong Wang Shanghai Rigen Biotechnology Co., Ltd. Shanghai, China

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Lei Dong Department of Pathology, Shanghai Rui Jin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China

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Zhiqiang Yin Thyroid Center, Shanghai Tenth People’s Hospital, Tongji University School of Medicine, Shanghai, China
Shanghai Center of Thyroid Diseases, Shanghai Tenth People’s Hospital, Tongji University School of Medicine, Shanghai, China

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Jian Fei Department of General Surgery, Pancreatic Disease Center, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
Research Institute of Pancreatic Diseases, Shanghai Jiao Tong University School of Medicine, Shanghai, China
State Key Laboratory of Oncogenes and Related Genes, Shanghai Cancer Institute, Shanghai Jiao Tong University, Shanghai, China
Institute of Translational Medicine, Shanghai Jiao Tong University, Shanghai, China

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cannot predict its progression. Therefore, ultrasound alone has relatively poor value for diagnosing malignant thyroid nodules. Further definitive diagnosis can be made by fine needle aspiration biopsy (FNAB), which is a cost-effective approach, but 16

Article Type:
Research Article
Collections:
Thyroid
DOI:
https://doi.org/10.1530/EC-23-0135
Volume/Issue:
Volume 12: Issue 8
Open access
Meihua Jin Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea

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Woo Kyung Lee Laboratory of Molecular Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA

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Mi-Hyeon You Asan Institute of Life Science, Asan Medical Center, Seoul, Korea

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Ahreum Jang Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea

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Sheue-yann Cheng Laboratory of Molecular Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA

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Won Gu Kim Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea

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Min Ji Jeon Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea

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Yu-Mi Lee Department of Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea

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types of thyroid cancers are also refractory to radioactive iodine ( 21 , 22 ). Early diagnosis and prognostication of aggressive thyroid cancer are important for appropriate management, but a better and unambiguous marker is needed. In this study, we

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-21-0135
Volume/Issue:
Volume 10: Issue 6
Open access
Caroline Y Hayashi Department of Internal Medicine, Botucatu Medical School, Sao Paulo State University (Unesp), Botucatu, São Paulo, Brazil

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Danilo T A Jaune Department of Internal Medicine, Botucatu Medical School, Sao Paulo State University (Unesp), Botucatu, São Paulo, Brazil

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Cristiano C Oliveira Department of Pathology, Botucatu Medical School, Sao Paulo State University (Unesp), Botucatu, São Paulo, Brazil

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Bárbara P Coelho Department of Surgery and Orthopedics, Botucatu Medical School, Sao Paulo State University (Unesp), Botucatu, São Paulo, Brazil

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Hélio A Miot Department of Dermatology, Botucatu Medical School, Sao Paulo State University (Unesp), Botucatu, São Paulo, Brazil

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Mariângela E A Marques Department of Pathology, Botucatu Medical School, Sao Paulo State University (Unesp), Botucatu, São Paulo, Brazil

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José Vicente Tagliarini Department of Otolaryngology and Head and Neck Surgery, Botucatu Medical School, Sao Paulo State University (Unesp), Botucatu, São Paulo, Brazil

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Emanuel C Castilho Department of Otolaryngology and Head and Neck Surgery, Botucatu Medical School, Sao Paulo State University (Unesp), Botucatu, São Paulo, Brazil

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Carlos S P Soares Department of Otolaryngology and Head and Neck Surgery, Botucatu Medical School, Sao Paulo State University (Unesp), Botucatu, São Paulo, Brazil

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Flávia R K Oliveira Department of Internal Medicine, Botucatu Medical School, Sao Paulo State University (Unesp), Botucatu, São Paulo, Brazil

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Paula Soares Instituto de Investigação e Inovação em Saúde (i3S), Universidade do Porto, Porto, Portugal
Cancer Signaling and Metabolism Group, Institute of Molecular Pathology and Immunology of the University of Porto (IPATIMUP), Porto, Portugal
Department of Pathology, Medical Faculty of the University of Porto, Porto, Portugal

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Gláucia M F S Mazeto Department of Internal Medicine, Botucatu Medical School, Sao Paulo State University (Unesp), Botucatu, São Paulo, Brazil

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classification system ( 2 ). Despite this system has proven extremely valid and reliable ( 3 ), a considerable number of cases still have an indeterminate cytological diagnosis. Of these, 'atypia of undetermined significance/follicular lesion of undetermined

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-20-0648
Volume/Issue:
Volume 10: Issue 7
Open access
Julia Beckhaus Department of Pediatrics and Pediatric Hematology/Oncology, University Children’s Hospital, Carl von Ossietzky Universität, Klinikum Oldenburg AöR, Oldenburg, Germany
Division of Epidemiology and Biometry, Carl von Ossietzky Universität, Oldenburg, Germany

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Maria Eveslage Institute of Biostatistics and Clinical Research, University of Münster, Münster, Germany

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Brigitte Bison Diagnostic and Interventional Neuroradiology, Faculty of Medicine, University of Augsburg, Augsburg, Germany

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Carsten Friedrich Department of Pediatrics and Pediatric Hematology/Oncology, University Children’s Hospital, Carl von Ossietzky Universität, Klinikum Oldenburg AöR, Oldenburg, Germany

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Hermann L Müller Department of Pediatrics and Pediatric Hematology/Oncology, University Children’s Hospital, Carl von Ossietzky Universität, Klinikum Oldenburg AöR, Oldenburg, Germany

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patients and their parents at the time of CP diagnosis were analyzed. Furthermore, we assessed the correlation of the patient’s BMI standard deviation score (SDS) at CP diagnosis and at follow-up with the parental BMI at CP diagnosis and the association of

Article Type:
Research Article
Collections:
Pituitary and Hypothalamus
DOI:
https://doi.org/10.1530/EC-24-0126
Volume/Issue:
Volume 13: Issue 8
Open access