Introduction Type 1 diabetes (T1D) is an autoimmune disorder characterized by insulin-producing β cell death caused by autoreactive T cells ( 1 ). T1D contributes to 10% of the total 422 million diabetes cases worldwide. Although T1D is no
The potential and challenges of alternative sources of β cells for the cure of type 1 diabetes
Monia Cito, Silvia Pellegrini, Lorenzo Piemonti, and Valeria Sordi
Update on the impact of type 2 diabetes mellitus on bone metabolism and material properties
Ann-Kristin Picke, Graeme Campbell, Nicola Napoli, Lorenz C Hofbauer, and Martina Rauner
Introduction The prevalence of diabetes mellitus is increasing worldwide with diabetes-related complications accounting for up to 60–70% of health-care costs related to diabetes ( 1 , 2 ). Besides the well-known renal and cardiovascular
Frequency and characteristics of diabetes in lipodystrophies and insulin receptoropathies compared with type 1 and type 2: results from the multicenter DPV registry
Clemens Kamrath, Alexander Eckert, Birgit Rami-Merhar, Sebastian Kummer, Martin Wabitsch, Katharina Laubner, Florian Kopp, Silvia Müther, Steffen Mühldorfer, and Reinhard W Holl
Introduction Diabetes mellitus due to insulin resistance is among the most prevalent endocrine disorders. It is commonly associated with obesity and lifestyle factors but may also occur in a very rare and severe form in patients with defects
Sex-specific modulation of circulating growth differentiation factor-15 in patients with type 2 diabetes and/or obesity
Mohamed Asrih, Flore Sinturel, Richard Dubos, Idris Guessous, Zoltan Pataky, Charna Dibner, François R Jornayvaz, and Karim Gariani
Introduction Obesity is rapidly increasing worldwide despite it being a major health concern ( 1 ). Excess weight represents a hazardous condition leading to the development of type 2 diabetes (T2D) and its complications, mainly cardiovascular
Gender difference in adrenal sensitivity to ACTH is abolished in type 2 diabetes
Lisa Arnetz, Neda Rajamand Ekberg, Kerstin Brismar, and Michael Alvarsson
Introduction Along with progressive β-cell failure and insulin resistance, patients with type 2 diabetes (T2D) display disturbed regulation of cortisol and insulin-like growth factor 1 (IGF1) secretion (1) . Especially regarding the hypothalamus
Diabetes in all hospitalized cases in Germany 2015–2019 and impact of the first COVID-19 year 2020
Marie Auzanneau, Alexander J Eckert, Andreas Fritsche, Martin Heni, Andrea Icks, Annabel S Mueller-Stierlin, Ana Dugic, Alexander Risse, Stefanie Lanzinger, and Reinhard W Holl
Introduction The prevalence of diabetes is increasing worldwide ( 1 ). The number of people with diabetes in Germany, which has been recently estimated as 6.2 million (about 10%) ( 2 ), is expected to reach more than 10 million people by 2040
Complex diseases and co-morbidities: polycystic ovary syndrome and type 2 diabetes mellitus
Raymond J Rodgers, Jodie C Avery, Vivienne M Moore, Michael J Davies, Ricardo Azziz, Elisabet Stener-Victorin, Lisa J Moran, Sarah A Robertson, Nigel K Stepto, Robert J Norman, and Helena J Teede
associated risk of gestational diabetes (GDM), impaired glucose tolerance, type 2 diabetes (DM2), non-alcoholic fatty liver disease (NAFLD), dyslipidaemia and increased risk factors for both cerebrovascular and cardiovascular disease ( 6 , 7 , 8 , 9
Continuous glucose monitoring reveals a novel association between duration and severity of hypoglycemia, and small nerve fiber injury in patients with diabetes
Hoda Gad, Einas Elgassim, Ibrahim Mohammed, Ahmad Yaser Alhaddad, Hussein Ahmed Hussein Zaky Aly, John-John Cabibihan, Abdulaziz Al-Ali, Kishor Kumar Sadasivuni, Aliyaa Haji, Neila Lamine, Adnan Khan, Ioannis N Petropoulos, Georgios Ponirakis, Alise Kalteniece, Maryam Ferdousi, Shazli Azmi, Uazman Alam, Wajeeha Abuhelaiqa, Amin Jayyousi, Dabia AlMohanadi, Khaled Baagar, and Rayaz A Malik
Introduction Diabetic peripheral neuropathy (DPN) affects ~50% of people with diabetes mellitus (T1DM) and (T2DM) ( 1 , 2 ). It has an insidious onset, which can lead to painful diabetic neuropathy, erectile dysfunction, foot ulceration and
The association of adiponectin with risk of pre-diabetes and diabetes in different subgroups: cluster analysis of a general population in south China
Xun Gong, Lili You, Feng Li, Qingyu Chen, Chaogang Chen, Xiaoyun Zhang, Xiuwei Zhang, Wenting Xuan, Kan Sun, Guojuan Lao, Chuan Wang, Yan Li, Mingtong Xu, Meng Ren, and Li Yan
Introduction Diabetes mellitus is a global public health issue that causes huge economic and medical burdens worldwide. The prevalence of diabetes has increased over the past few decades, especially in Asian population ( 1 ). A national cross
Glucocorticoid-induced diabetes in patients with metastatic spinal cord compression
Helga Schultz, Svend Aage Engelholm, Eva Harder, Ulrik Pedersen-Bjergaard, and Peter Lommer Kristensen
(MSCC) and brain tumours. Diabetes mellitus (DM) is a well-known metabolic side effect from treatment with glucocorticoids. The diabetogenic effect is mainly a result of insulin resistance in muscle and fatty tissue, increased production of glucose from
