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Department of Clinical Sciences and Community Health, University of Milan, Milan, Italy
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desmopressin testing, a procedure also used during the diagnostic work-up of Cushing’s disease. Administration of desmopressin, a long-acting vasopressin analog, has in fact proven useful to distinguish Cushing’s disease from pseudo-Cushing states ( 8 , 9
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. Desmopressin (DDAVP, a synthetic AVP analogue) reduces uncontrolled water excretion in CDI and is commonly used in treatment. Critically, loss of thirst perception (through primary pathology or reduced consciousness) or limited access to water (through non
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National Center for Neurological Disorders, Shanghai, China
Shanghai Clinical Medical Center of Neurosurgery, Shanghai, China
Neurosurgical Institute of Fudan University, Shanghai, China
Shanghai Key Laboratory of Medical Brain Function and Restoration and Neural Regeneration, Fudan University, Shanghai, China
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National Center for Neurological Disorders, Shanghai, China
Shanghai Clinical Medical Center of Neurosurgery, Shanghai, China
Neurosurgical Institute of Fudan University, Shanghai, China
Shanghai Key Laboratory of Medical Brain Function and Restoration and Neural Regeneration, Fudan University, Shanghai, China
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, serum sodium level, and a need for desmopressin treatment were comprehensively evaluated for the diagnosis of central arginine vasopressin deficiency. We developed models to predict postoperative hypernatremia. In the training cohort, we used
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DI and elevated in nephrogenic DI, reflecting inappropriate AVP action. In addition, the administration of the AVP analog desmopressin acetate at the end of the test may help to differentiate central from nephrogenic DI, as the antidiuretic response
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(cyclical CS) ( 7 , 8 , 9 ). Ovine or hCRH and/or desmopressin have been used to stimulate corticotropes during BIPSS to improve the accuracy of the procedure for localizing the source of ACTH hypersecretion and were found to be equipotent in stimulating
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Department of Molecular Surgery and Medicine, Karolinska Institute, Stockholm, Sweden
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increase should be limited to 10–12 mmol/L in the first 24 h and to 8 mmol/L/day in the following days until a sNA of 130 mmol/L is obtained. Limiting the increase of sNA is difficult, but is greatly facilitated by the introduction of desmopressin (see the
Department of Oncology and Metabolism, The Medical School, The University of Sheffield, Sheffield, UK
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Department of Oncology and Metabolism, The Medical School, The University of Sheffield, Sheffield, UK
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) of the total cohort (i.v. dextrose = 17, desmopressin = 2, both = 3). These were mostly provided outside of general wards, especially desmopressin which was given exclusively in high dependency/intensive care units. Details of the patients who
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ratio >2. * Stimulation with desmopressin. ** Stimulation with CRH+desmopressin. *** Not known if procedures were done with or without use of CRH. **** Not known if procedures were done with CRH or desmopressin. ° None pathologically
Department of Medicine, Universidad Cardenal Herrera-CEU, CEU Universities, Castellón, Spain
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results of postoperative basal cortisol, among which are: corticotropin-releasing hormone test ( 27 ), metyrapone test ( 28 ), desmopressin test ( 29 , 30 ) and dexamethasone suppression test after desmopressin ( 31 ). For the interpretation of these last
Collaborating Center for the WHO Family of International Classifications in China, Beijing, China
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Key Laboratory of Endocrinology of National Health Commission of People’s Republic of China, Beijing, China
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China Pituitary Disease Registry Center, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China
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China Pituitary Disease Registry Center, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China
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Clinical Epidemiology Unit, International Epidemiology Network, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
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Collaborating Center for the WHO Family of International Classifications in China, Beijing, China
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China Pituitary Disease Registry Center, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China
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-enhanced MRI of the pituitary glands and plain and contrasted enhanced computed tomography (CT) of the adrenal, thoracoabdominal and pelvic areas. Since bilateral inferior petrosal sinus sampling (BIPSS) with desmopressin (DDAVP) has been demonstrated to have