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Eva Olga Melin, Jonatan Dereke, Maria Thunander, and Magnus Hillman

Introduction Depression is associated with type 1 diabetes (T1D), Alzheimer’s disease, increased coronary heart disease and both coronary and all-cause mortality ( 1 , 2 , 3 ). T1D has a serious impact on mental health, indicated by the more

Open access

Greta B Raglan, Louis A Schmidt, and Jay Schulkin

the presentation of clinical disorders. Depression and anxiety Although diagnostic criteria for anxiety and depressive disorders such as generalized anxiety disorder and major depressive disorder are unique and diverse, they are generally

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Lukas Engler, Christian Adolf, Daniel A Heinrich, Anna-Katharine Brem, Anna Riester, Anna Franke, Felix Beuschlein, Martin Reincke, Axel Steiger, and Heike Künzel

Introduction Patients with primary aldosteronism (PA) are thought to be a natural model for chronic aldosterone excess, showing significantly higher scores for depression and anxiety compared to the general population, with females being more

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Yen Kheng Tan, Yu Heng Kwan, David Choon Liang Teo, Marieke Velema, Jaap Deinum, Pei Ting Tan, Meifen Zhang, Joan Joo Ching Khoo, Wann Jia Loh, Linsey Gani, Thomas F J King, Eberta Jun Hui Tan, Shui Boon Soh, Vanessa Shu Chuan Au, Tunn Lin Tay, Lily Mae Quevedo Dacay, Keng Sin Ng, Kang Min Wong, Andrew Siang Yih Wong, Foo Cheong Ng, Tar Choon Aw, Yvonne Hui Bin Chan, Khim Leng Tong, Sheldon Shao Guang Lee, Siang Chew Chai, and Troy Hai Kiat Puar

depression ( 4 , 5 ). Generally, bilateral PA is treated with mineralocorticoid receptor (MR) antagonists, while unilateral PA is managed with unilateral adrenalectomy ( 6 ). Studies have found better cardiovascular events and HRQoL outcomes following

Open access

Sheila Leone, Lucia Recinella, Annalisa Chiavaroli, Claudio Ferrante, Giustino Orlando, Michele Vacca, Roberto Salvatori, and Luigi Brunetti

pituitary GH secretion. We have also observed that −/− mice have decreased anxiety- and depression-related behaviour ( Figs 7 and 8 ), excluding any stress-induced behavioural inhibition, confirming previous results ( 12 ). Additionally, −/− mice

Open access

Eva O Melin, Jonatan Dereke, Maria Thunander, and Magnus Hillman

pathogenesis of DR occurs by alterations in multiple biochemical pathways, which involve several metabolic, inflammatory and endocrine responses ( 1 , 2 , 4 , 6 ). Depression is the most common psychiatric disorder worldwide with great impact not only on

Open access

Dorte Glintborg, Magda Lambaa Altinok, Pernille Ravn, Kurt Bjerregaard Stage, Kurt Højlund, and Marianne Andersen

obesity predicts the development of type 2 diabetes mellitus in PCOS ( 3 ). Furthermore, obesity predicted poor quality of life in women with PCOS ( 4 ), and the risk of depression was 2–5 times increased in PCOS ( 5 , 6 ). PCOS is characterized by

Open access

Emmi Naskali, Katja Dettmer, Peter J Oefner, Pedro A B Pereira, Kai Krohn, Petri Auvinen, Annamari Ranki, and Nicolas Kluger

symptoms in 29% of Finnish APECED patients ( 13 ). Besides, alteration of gut microbiome composition has been shown to be associated with various diseases such as mental depression and autoimmune diseases ( 14 ). It has become evident that gut microbes

Open access

Eva Olga Melin, Magnus Hillman, and Mona Landin-Olsson

inactivity ( 10 ), smoking ( 11 ), and depression ( 12 ), and higher blood pressure (BP) have been observed in men ( 13 ). Increased cortisol secretion is one factor that might contribute to treatment-resistant hypertension ( 14 ). Increased cortisol

Open access

Natasha Bergmann, Søren Ballegaard, Pernille Holmager, Per Bech, Åke Hjalmarson, Finn Gyntelberg, and Jens Faber

Introduction The risk of depression in people with diabetes is two times higher when compared with patients without diabetes, and major depression and elevated depressive symptoms have been found to be present in 11 and 31%, respectively, of