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Gaëtan Prévost Normandie Univ, UNIROUEN, INSERM U1239, Laboratory of Neuronal and Neuroendocrine Differentiation and Communication (DC2N), Rouen, France
Department of Endocrinology, Diabetes and Metabolic Diseases, Normandie Univ, UNIROUEN, Rouen University Hospital, Rouen, France
Centre d’Investigation Clinique (CIC-CRB)-INSERM 1404, Rouen University Hospital, Rouen, France

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Marie Picot Normandie Univ, UNIROUEN, INSERM U1239, Laboratory of Neuronal and Neuroendocrine Differentiation and Communication (DC2N), Rouen, France

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Marie-Anne Le Solliec Normandie Univ, UNIROUEN, INSERM U1239, Laboratory of Neuronal and Neuroendocrine Differentiation and Communication (DC2N), Rouen, France

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Arnaud Arabo Normandie Univ, UNIROUEN, INSERM U1239, Laboratory of Neuronal and Neuroendocrine Differentiation and Communication (DC2N), Rouen, France

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Hind Berrahmoune Normandie Univ, UNIROUEN, INSERM U1239, Laboratory of Neuronal and Neuroendocrine Differentiation and Communication (DC2N), Rouen, France
Department of Endocrinology, Diabetes and Metabolic Diseases, Normandie Univ, UNIROUEN, Rouen University Hospital, Rouen, France
Centre d’Investigation Clinique (CIC-CRB)-INSERM 1404, Rouen University Hospital, Rouen, France

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Mouna El Mehdi Normandie Univ, UNIROUEN, INSERM U1239, Laboratory of Neuronal and Neuroendocrine Differentiation and Communication (DC2N), Rouen, France

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Saloua Cherifi Normandie Univ, UNIROUEN, INSERM U1239, Laboratory of Neuronal and Neuroendocrine Differentiation and Communication (DC2N), Rouen, France

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Alexandre Benani Center for Taste and Feeding Behaviour, CNRS (UMR6265), INRA (UMR1324), Université de Bourgogne-Franche Comté, Dijon , France

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Emmanuelle Nédélec Center for Taste and Feeding Behaviour, CNRS (UMR6265), INRA (UMR1324), Université de Bourgogne-Franche Comté, Dijon , France

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Françoise Gobet Department of Anatomopathophysiology, Normandie Univ, UNIROUEN, Rouen University Hospital, Rouen, France

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Valéry Brunel Department of Biochemistry, Normandie Univ, UNIROUEN, Rouen University Hospital, Rouen, France

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Jérôme Leprince Normandie Univ, UNIROUEN, INSERM U1239, Laboratory of Neuronal and Neuroendocrine Differentiation and Communication (DC2N), Rouen, France

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Hervé Lefebvre Normandie Univ, UNIROUEN, INSERM U1239, Laboratory of Neuronal and Neuroendocrine Differentiation and Communication (DC2N), Rouen, France
Department of Endocrinology, Diabetes and Metabolic Diseases, Normandie Univ, UNIROUEN, Rouen University Hospital, Rouen, France
Centre d’Investigation Clinique (CIC-CRB)-INSERM 1404, Rouen University Hospital, Rouen, France

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Youssef Anouar Normandie Univ, UNIROUEN, INSERM U1239, Laboratory of Neuronal and Neuroendocrine Differentiation and Communication (DC2N), Rouen, France

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Nicolas Chartrel Normandie Univ, UNIROUEN, INSERM U1239, Laboratory of Neuronal and Neuroendocrine Differentiation and Communication (DC2N), Rouen, France

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Introduction Glucose homeostasis is a crucial parameter to maintain normal body function. Control of blood glucose levels is ensured by a highly sophisticated network of various hormones released by the pancreas, intestine, liver, adipose and

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-19-0247
Volume/Issue:
Volume 8: Issue 7
Open access
Chunliang Yang Department of Integrated Traditional Chinese and Western Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
The Center for Biomedical Research, Tongji Hospital Research Building, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China

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Junyi Li Department of Integrated Traditional Chinese and Western Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China

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Fei Sun The Center for Biomedical Research, Tongji Hospital Research Building, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China

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Haifeng Zhou Department of Integrated Traditional Chinese and Western Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China

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Jia Yang Department of Integrated Traditional Chinese and Western Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China

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Chao Yang Department of Gerontology, Hubei Provincial Hospital of Integrated Chinese and Western Medicine, Wuhan, China

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blood glucose fluctuation; however, it is unclear whether SGK1 is implicated and what role it plays in hyperglycemia-induced muscle wasting. Adipose tissue is deemed to be a key modulator of fuel metabolism and glucose homeostasis. Despite high salt

Article Type:
Review Article
DOI:
https://doi.org/10.1530/EC-20-0225
Volume/Issue:
Volume 9: Issue 7
Open access
Wenqi Yang Center for Scientific Research and Institute of Exercise and Health, Guangzhou Sports University, Guangzhou, China
Key Laboratory of Sports Technique, Tactics and Physical Function of General Administration of Sport of China, Scientific Research Center, Guangzhou Sport University, Guangzhou, China

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Ling Liu Key Laboratory of Sports Technique, Tactics and Physical Function of General Administration of Sport of China, Scientific Research Center, Guangzhou Sport University, Guangzhou, China

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Yuan Wei Center for Scientific Research and Institute of Exercise and Health, Guangzhou Sports University, Guangzhou, China
Key Laboratory of Sports Technique, Tactics and Physical Function of General Administration of Sport of China, Scientific Research Center, Guangzhou Sport University, Guangzhou, China

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Chunlu Fang Center for Scientific Research and Institute of Exercise and Health, Guangzhou Sports University, Guangzhou, China
Key Laboratory of Sports Technique, Tactics and Physical Function of General Administration of Sport of China, Scientific Research Center, Guangzhou Sport University, Guangzhou, China

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Fu Zhou Key Laboratory of Sports Technique, Tactics and Physical Function of General Administration of Sport of China, Scientific Research Center, Guangzhou Sport University, Guangzhou, China

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Jinbao Chen Key Laboratory of Sports Technique, Tactics and Physical Function of General Administration of Sport of China, Scientific Research Center, Guangzhou Sport University, Guangzhou, China

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Qinghua Han Key Laboratory of Sports Technique, Tactics and Physical Function of General Administration of Sport of China, Scientific Research Center, Guangzhou Sport University, Guangzhou, China

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Meifang Huang Key Laboratory of Sports Technique, Tactics and Physical Function of General Administration of Sport of China, Scientific Research Center, Guangzhou Sport University, Guangzhou, China

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Xuan Tan Key Laboratory of Sports Technique, Tactics and Physical Function of General Administration of Sport of China, Scientific Research Center, Guangzhou Sport University, Guangzhou, China

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Qiuyue Liu Key Laboratory of Sports Technique, Tactics and Physical Function of General Administration of Sport of China, Scientific Research Center, Guangzhou Sport University, Guangzhou, China

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Qiang Pan Key Laboratory of Sports Technique, Tactics and Physical Function of General Administration of Sport of China, Scientific Research Center, Guangzhou Sport University, Guangzhou, China

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Lu Zhang Key Laboratory of Sports Technique, Tactics and Physical Function of General Administration of Sport of China, Scientific Research Center, Guangzhou Sport University, Guangzhou, China

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Xiaojuan Lei Key Laboratory of Sports Technique, Tactics and Physical Function of General Administration of Sport of China, Scientific Research Center, Guangzhou Sport University, Guangzhou, China

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Liangming Li Center for Scientific Research and Institute of Exercise and Health, Guangzhou Sports University, Guangzhou, China
Key Laboratory of Sports Technique, Tactics and Physical Function of General Administration of Sport of China, Scientific Research Center, Guangzhou Sport University, Guangzhou, China

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 ± SEM. n  = 10 per group. a P  < 0.05 for difference from LFD; b P  < 0.05 for difference from HFD. Exercise protects against deranged glucose homeostasis under a HFD challenge Fasting blood glucose and insulin levels were

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-19-0034
Volume/Issue:
Volume 8: Issue 5
Open access
Melinda Kertész Department of Medicine and Nephrology-Diabetes Centre, Medical School, University of Pécs, Pécs, Baranya, Hungary

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Szilárd Kun Department of Medicine and Nephrology-Diabetes Centre, Medical School, University of Pécs, Pécs, Baranya, Hungary

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Eszter Sélley Department of Medicine and Nephrology-Diabetes Centre, Medical School, University of Pécs, Pécs, Baranya, Hungary

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Zsuzsanna Nagy Department of Medicine and Nephrology-Diabetes Centre, Medical School, University of Pécs, Pécs, Baranya, Hungary

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Tamás Kőszegi Department of Laboratory Medicine, Medical School, University of Pécs, Pécs, Baranya, Hungary

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István Wittmann Department of Medicine and Nephrology-Diabetes Centre, Medical School, University of Pécs, Pécs, Baranya, Hungary

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level, blood pressure, and heart rate) should also be measured. Metformin is used in prediabetes and in type 2 diabetic patients to treat insulin resistance resulting in a decreased level of plasma glucose and triglycerides, leading in this way to a

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-21-0218
Volume/Issue:
Volume 10: Issue 7
Open access
Gunjan Garg Departments of Endocrinology, Obstetrics and Gynecology, Biostatics

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Garima Kachhawa Departments of Endocrinology, Obstetrics and Gynecology, Biostatics

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Rekha Ramot Departments of Endocrinology, Obstetrics and Gynecology, Biostatics

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Rajesh Khadgawat Departments of Endocrinology, Obstetrics and Gynecology, Biostatics

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Nikhil Tandon Departments of Endocrinology, Obstetrics and Gynecology, Biostatics

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V Sreenivas Departments of Endocrinology, Obstetrics and Gynecology, Biostatics

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Alka Kriplani Departments of Endocrinology, Obstetrics and Gynecology, Biostatics

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N Gupta Departments of Endocrinology, Obstetrics and Gynecology, Biostatics

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times and the mean value of second and third recordings was considered. Parameters of IR IR – was calculated by a computer-based model called HOMA-IR utilizing fasting blood glucose and fasting serum insulin levels (24) . The whole-body IS index (WBISI

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-15-0001
Volume/Issue:
Volume 4: Issue 2
Open access
Marloes Emous Centre for Obesity Northern-Netherlands (CON), Medical Centre Leeuwarden, Leeuwarden, The Netherlands

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Merel van den Broek Centre for Obesity Northern-Netherlands (CON), Medical Centre Leeuwarden, Leeuwarden, The Netherlands

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Ragnhild B Wijma Centre for Obesity Northern-Netherlands (CON), Medical Centre Leeuwarden, Leeuwarden, The Netherlands

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Loek J M de Heide Centre for Obesity Northern-Netherlands (CON), Medical Centre Leeuwarden, Leeuwarden, The Netherlands

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Gertjan van Dijk GELIFES-Neurobiology, Department of Behavioral Neuroscience, University of Groningen, Groningen, The Netherlands

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Anke Laskewitz Certe Laboratories, Medical Center Leeuwarden, Leeuwarden, The Netherlands

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Erik Totté Centre for Obesity Northern-Netherlands (CON), Medical Centre Leeuwarden, Leeuwarden, The Netherlands

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Bruce H R Wolffenbuttel Department of Endocrinology, University of Groningen, University Medical Centre Groningen, Groningen, The Netherlands

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André P van Beek Centre for Obesity Northern-Netherlands (CON), Medical Centre Leeuwarden, Leeuwarden, The Netherlands
Department of Endocrinology, University of Groningen, University Medical Centre Groningen, Groningen, The Netherlands

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which 13.8 g is sugars), 9.84 g fat and 154.9 g water. The patients were asked to finish the meal within 10 min. Blood analyses Venous blood for glucose and insulin analysis was collected in lithium–heparin tubes with a gel separator. For the

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-19-0268
Volume/Issue:
Volume 8: Issue 7
Open access
Jia Liu Department of Endocrinology, Beijing Chao-yang Hospital, Capital Medical University, Chaoyang District, Beijing, China

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Lin Zhang Department of Endocrinology, Beijing Chao-yang Hospital, Capital Medical University, Chaoyang District, Beijing, China

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Jing Fu Department of Endocrinology, Beijing Chao-yang Hospital, Capital Medical University, Chaoyang District, Beijing, China

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Qiu Wang Department of Endocrinology, Beijing Chao-yang Hospital, Capital Medical University, Chaoyang District, Beijing, China

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Guang Wang Department of Endocrinology, Beijing Chao-yang Hospital, Capital Medical University, Chaoyang District, Beijing, China

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, fasting blood glucose; FINS, fasting insulin; HbA1c, hemoglobin A1c; HC, hip circumference; HDL-C, high-density lipoprotein cholesterol; HOMA-IR, homeostasis model assessment of insulin resistance; hsCRP, high-sensitivity C-reactive protein; LDL-C, low

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-21-0040
Volume/Issue:
Volume 10: Issue 4
Open access
Ahmet Uçar
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Nurçin Saka
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Firdevs Baş
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Nihal Hatipoğlu Pediatric Endocrine Unit, Pediatric Endocrine Unit, Istanbul Medical Faculty, Istanbul University, 34093 Fatih, Istanbul, Turkey

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Rüveyde Bundak
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Feyza Darendeliler
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blood samples for glucose and lipids (total cholesterol, high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol, and triglycerides (TGs)), serum insulin, LH, FSH, DHEAS, total testosterone, and high-sensitivity C

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-12-0059
Volume/Issue:
Volume 2: Issue 1
Open access
Eliana Piantanida Department of Medicine and Surgery, University of Insubria, Varese, Italy

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Daniela Gallo Department of Medicine and Surgery, University of Insubria, Varese, Italy

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Giovanni Veronesi Department of Medicine and Surgery, University of Insubria, Varese, Italy
Research Center in Epidemiology and Preventive Medicine (EPIMED), University of Insubria, Varese, Italy

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Eugenia Dozio Department of Medicine and Surgery, University of Insubria, Varese, Italy

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Eugenia Trotti Department of Medicine and Surgery, University of Insubria, Varese, Italy

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Adriana Lai Department of Medicine and Surgery, University of Insubria, Varese, Italy

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Silvia Ippolito Department of Medicine and Surgery, University of Insubria, Varese, Italy

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Jessica Sabatino Department of Medicine and Surgery, University of Insubria, Varese, Italy

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Maria Laura Tanda Department of Medicine and Surgery, University of Insubria, Varese, Italy

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Antonio Toniolo Department of Biotechnology and Life Science, University of Insubria, Varese, Italy

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Marco Ferrario Department of Medicine and Surgery, University of Insubria, Varese, Italy
Research Center in Epidemiology and Preventive Medicine (EPIMED), University of Insubria, Varese, Italy

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Luigi Bartalena Department of Medicine and Surgery, University of Insubria, Varese, Italy

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/or DBP ≥85 mmHg); impaired fasting glucose (IFG) (≥100 mg/dL) or on-going treatment for any of the above conditions. Blood tests and vitamin D status Fasting venous blood samples were collected in 2 consecutive days, after an overnight fast

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-17-0304
Volume/Issue:
Volume 6: Issue 8
Open access
Ling Hu Department of Endocrinology, The Third Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, China

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Ting Li Department of Endocrinology, The Third Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, China

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Xiao-Ling Yin Department of Endocrinology, The Third Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, China

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Yi Zou Department of Endocrinology, The Third Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, China

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least 8–10 h of fasting. The serum samples were uniformly tested within l–3 h. Fasting blood glucose (FBG) level was determined by the glucose oxidase method. Triglycerides, total cholesterol, low-density lipoprotein cholesterol (LDL-C), and high

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-20-0398
Volume/Issue:
Volume 9: Issue 9
Open access