Agata Hanna Bryk-Wiązania
Agata Hanna Bryk-Wiązania
Chair and Department of Endocrinology, Jagiellonian University Medical College, Krakow, Poland
Department of Endocrinology, Oncological Endocrinology and Nuclear Medicine, University Hospital, Krakow, Poland
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Department of Endocrinology, Oncological Endocrinology and Nuclear Medicine, University Hospital, Krakow, Poland
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Mari Minasyan
Mari Minasyan
Department of Endocrinology, Oncological Endocrinology and Nuclear Medicine, University Hospital, Krakow, Poland
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Alicja Hubalewska-Dydejczyk
Alicja Hubalewska-Dydejczyk
Chair and Department of Endocrinology, Jagiellonian University Medical College, Krakow, Poland
Department of Endocrinology, Oncological Endocrinology and Nuclear Medicine, University Hospital, Krakow, Poland
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Department of Endocrinology, Oncological Endocrinology and Nuclear Medicine, University Hospital, Krakow, Poland
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Aleksandra Gilis-Januszewska
Aleksandra Gilis-Januszewska
Chair and Department of Endocrinology, Jagiellonian University Medical College, Krakow, Poland
Department of Endocrinology, Oncological Endocrinology and Nuclear Medicine, University Hospital, Krakow, Poland
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Department of Endocrinology, Oncological Endocrinology and Nuclear Medicine, University Hospital, Krakow, Poland
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platelets, increased thrombin generation, elevated concentrations of fibrinogen and fibrinolysis inhibitors, and compensatory elevation of endogenous anticoagulants such as protein C and protein S ( 3 , 4 , 5 , 6 ). However, no linear relationship with
Mette Bøgehave
Mette Bøgehave
Department of Clinical Biochemistry, Hospital South West Jutland, University Hospital of Southern Denmark, Esbjerg, Denmark
Unit for Thrombosis Research, Department of Regional Health Research, University of Southern Denmark, Denmark
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Unit for Thrombosis Research, Department of Regional Health Research, University of Southern Denmark, Denmark
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Dorte Glintborg
Dorte Glintborg
Department of Endocrinology, Odense University Hospital, Odense, Denmark
Department of Clinical Research, University of Southern Denmark, Odense, Denmark
OPEN, Open Patient data Explorative Network, Odense University Hospital, Region of Southern Denmark, Odense, Denmark
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Department of Clinical Research, University of Southern Denmark, Odense, Denmark
OPEN, Open Patient data Explorative Network, Odense University Hospital, Region of Southern Denmark, Odense, Denmark
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Jørgen Brodersen Gram
Jørgen Brodersen Gram
Department of Clinical Biochemistry, Hospital South West Jutland, University Hospital of Southern Denmark, Esbjerg, Denmark
Unit for Thrombosis Research, Department of Regional Health Research, University of Southern Denmark, Denmark
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Unit for Thrombosis Research, Department of Regional Health Research, University of Southern Denmark, Denmark
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Else-Marie Bladbjerg
Else-Marie Bladbjerg
Department of Clinical Biochemistry, Hospital South West Jutland, University Hospital of Southern Denmark, Esbjerg, Denmark
Unit for Thrombosis Research, Department of Regional Health Research, University of Southern Denmark, Denmark
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Unit for Thrombosis Research, Department of Regional Health Research, University of Southern Denmark, Denmark
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Marianne Skovsager Andersen
Marianne Skovsager Andersen
Department of Endocrinology, Odense University Hospital, Odense, Denmark
Department of Clinical Research, University of Southern Denmark, Odense, Denmark
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Department of Clinical Research, University of Southern Denmark, Odense, Denmark
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Johannes Jakobsen Sidelmann
Johannes Jakobsen Sidelmann
Department of Clinical Biochemistry, Hospital South West Jutland, University Hospital of Southern Denmark, Esbjerg, Denmark
Unit for Thrombosis Research, Department of Regional Health Research, University of Southern Denmark, Denmark
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Unit for Thrombosis Research, Department of Regional Health Research, University of Southern Denmark, Denmark
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). CVD can be caused by atherosclerosis and thrombosis, and alterations in the coagulation system ( Fig. 1 ) contribute significantly to the pathogenesis of thrombosis. It remains unclear whether TRT induces a pro- or anticoagulant state. Reportedly
Eng-Loon Tng
Eng-Loon Tng
Department of Medicine, Level 8, Tower A, Ng Teng Fong General Hospital, Singapore
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Yee Sian Tiong
Yee Sian Tiong
Department of Medicine, Level 8, Tower A, Ng Teng Fong General Hospital, Singapore
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Aye Thida Aung
Aye Thida Aung
Department of Medicine, Level 8, Tower A, Ng Teng Fong General Hospital, Singapore
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Nicole Ya Yuan Chong
Nicole Ya Yuan Chong
Department of Medicine, National University Hospital, Singapore
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Zhemin Wang
Zhemin Wang
Department of Medicine, National University Hospital, Singapore
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). However, warfarin and direct oral anticoagulants (DOACs) did not prevent stroke in two retrospective cohort studies ( 6 , 15 ). There are no systematic reviews or Cochrane reviews on this topic. Materials and methods The primary objective is the
M Cherenko
M Cherenko
Department of Medicine, Division of Endocrinology, Leiden University Medical Centre, Leiden, Netherlands
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N M Appelman-Dijkstra
N M Appelman-Dijkstra
Department of Medicine, Division of Endocrinology, Leiden University Medical Centre, Leiden, Netherlands
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A L Priego Zurita
A L Priego Zurita
Department of Medicine, Division of Endocrinology, Leiden University Medical Centre, Leiden, Netherlands
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N R Biermasz
N R Biermasz
Department of Medicine, Division of Endocrinology, Leiden University Medical Centre, Leiden, Netherlands
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O M Dekkers
O M Dekkers
Department of Medicine, Division of Endocrinology, Leiden University Medical Centre, Leiden, Netherlands
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F A Klok
F A Klok
Department of Medicine, Division of Thrombosis and Haemostasis, Leiden University Medical Centre, Leiden, Netherlands
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N Reisch
N Reisch
Department of Medicine IV, LMU University Hospital, LMU Munich, Munich, Germany
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A Aulinas
A Aulinas
Department of Endocrinology, Fundacio de Gestio Sanitaria Hospital de la Santa Creu i Sant Pau, IR-SantPau and CIBERER Unit 747 (ISCIII), Barcelona, Spain
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B Biagetti
B Biagetti
Department of Endocrinology, Hospital Universitari Vall d’Hebron, Barcelona, Spain
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S Cannavo
S Cannavo
Endocrine Unit, University Hospital AOU Policlinico G. Martino, Messina, Italy
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L Canu
L Canu
University Hospital Florence Careggi, Florence, Italy
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M Detomas
M Detomas
Department of Internal Medicine, University Hospital Würzburg, Wuerzburg, Germany
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F Devuyst
F Devuyst
Department of Endocrinology, Hôpital Universitaire de Bruxelles, Hôpital Erasme, Brussels, Belgium
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H Falhammar
H Falhammar
Department of Endocrinology, Karolinska University Hospital and Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden
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R A Feelders
R A Feelders
Department of Internal Medicine, Division of Endocrinology, Erasmus MC, Rotterdam, Netherlands
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F Ferrau
F Ferrau
Endocrine Unit, University Hospital AOU Policlinico G. Martino, Messina, Italy
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F Gatto
F Gatto
IRCCS Ospedale Policlinico San Martino, Genova, Genoa, Italy
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C Grasselli
C Grasselli
Cardiovascular Medicine Unit, AUSL-IRCCS, Reggio Emilia, Italy
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P van Houten
P van Houten
Department of Internal Medicine, Division of Endocrinology, Radboud University Medical Center, Nijmegen, Netherlands
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C Hoybye
C Hoybye
Department of Endocrinology, Karolinska University Hospital and Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden
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A M Isidori
A M Isidori
Department of Experimental Medicine, Sapienza University of Rome, Rome, Italy
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A Kyrilli
A Kyrilli
Department of Endocrinology, Hôpital Universitaire de Bruxelles, Hôpital Erasme, Brussels, Belgium
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P Loli
P Loli
Division of Endocrinology, San Raffaele Vita-Salute University, IRCCS San Raffaele Hospital Milan, Italy
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D Maiter
D Maiter
Department of Endocrinology, Cliniques universitaires Saint-Luc – UCLouvain, Brussels, Belgium
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E Nowak
E Nowak
Department of Medicine IV, LMU University Hospital, LMU Munich, Munich, Germany
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R Pivonello
R Pivonello
Dipartimento di Medicina Clinica e Chirurgia, Sezione di Endocrinologia, Diabetologia, Andrologia e Nutrizione, Università “Federico II” di Napoli, Naples, Italy
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O Ragnarsson
O Ragnarsson
Sahlgrenska Academy, Wallenberg Centre for Molecular and Translational Medicine, Institute of Medicine (O.R.), University of Gothenburg, Sweden
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R V Steenaard
R V Steenaard
Department of Internal Medicine, Máxima MC, Veldhoven, Netherlands
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N Unger
N Unger
University Hospital Essen, Department of Endocrinology, Diabetes and Metabolism, Essen, Germany
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A van de Ven
A van de Ven
Department of Internal Medicine, Division of Endocrinology, Radboud University Medical Center, Nijmegen, Netherlands
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S M Webb
S M Webb
Department of Endocrinology, Fundacio de Gestio Sanitaria Hospital de la Santa Creu i Sant Pau, IR-SantPau and CIBERER Unit 747 (ISCIII), Barcelona, Spain
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D Yeste
D Yeste
Pediatric Endocrinology Service, Hospital Universitari Vall d’Hebron, Universitat Autònoma de Barcelona, Barcelona, Spain. CIBER Enfermedades Raras, Instituto Carlos III, Madrid, Spain
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S F Ahmed
S F Ahmed
Department of Medicine, Division of Endocrinology, Leiden University Medical Centre, Leiden, Netherlands
University of Glasgow, Office for Rare Conditions, Glasgow, UK
University of Glasgow, Developmental Endocrinology Research Group, Royal Hospital for Children, Glasgow, UK
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University of Glasgow, Office for Rare Conditions, Glasgow, UK
University of Glasgow, Developmental Endocrinology Research Group, Royal Hospital for Children, Glasgow, UK
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A M Pereira
A M Pereira
Department of Endocrinology & Metabolism, Amsterdam University Medical Centre, Amsterdam, Noord-Holland, Netherlands
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concentrations ( 11 , 12 ), impaired fibrinolysis ( 4 ) and endothelial dysfunction ( 13 ). Changes in pro- and anticoagulant factors may persist after successful surgery or medical therapy for at least several months ( 14 , 15 ). Given the lack of evidence
Eva Novoa
Eva Novoa
Department of Otorhinolaryngology, Clinic of Endocrinology, Head and Neck Surgery
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Marcel Gärtner
Marcel Gärtner
Department of Otorhinolaryngology, Clinic of Endocrinology, Head and Neck Surgery
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Christoph Henzen
Christoph Henzen
Department of Otorhinolaryngology, Clinic of Endocrinology, Head and Neck Surgery
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, infections, particularly middle ear infections, trauma or surgery, and possible drug interactions with dexamethasone (i.e. antidiabetic, anticonvulsants, oral anticoagulants, antihypertensives, antidepressants, NSAID, and statins), as well as blood glucose
Ali Abbara
Ali Abbara
Department of Investigative Medicine, Imperial College London, Hammersmith Hospital, London, UK
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Sophie Clarke
Sophie Clarke
Department of Investigative Medicine, Imperial College London, Hammersmith Hospital, London, UK
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Pei Chia Eng
Pei Chia Eng
Department of Investigative Medicine, Imperial College London, Hammersmith Hospital, London, UK
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James Milburn
James Milburn
Imperial College Healthcare NHS Trust, London, UK
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Devavrata Joshi
Devavrata Joshi
Imperial College Healthcare NHS Trust, London, UK
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Alexander N Comninos
Alexander N Comninos
Department of Investigative Medicine, Imperial College London, Hammersmith Hospital, London, UK
Imperial College Healthcare NHS Trust, London, UK
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Imperial College Healthcare NHS Trust, London, UK
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Rozana Ramli
Rozana Ramli
Imperial College Healthcare NHS Trust, London, UK
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Amrish Mehta
Amrish Mehta
Imperial College Healthcare NHS Trust, London, UK
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Brynmor Jones
Brynmor Jones
Imperial College Healthcare NHS Trust, London, UK
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Florian Wernig
Florian Wernig
Imperial College Healthcare NHS Trust, London, UK
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Ramesh Nair
Ramesh Nair
Imperial College Healthcare NHS Trust, London, UK
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Nigel Mendoza
Nigel Mendoza
Imperial College Healthcare NHS Trust, London, UK
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Amir H Sam
Amir H Sam
Department of Investigative Medicine, Imperial College London, Hammersmith Hospital, London, UK
Imperial College Healthcare NHS Trust, London, UK
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Imperial College Healthcare NHS Trust, London, UK
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Emma Hatfield
Emma Hatfield
Imperial College Healthcare NHS Trust, London, UK
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Karim Meeran
Karim Meeran
Department of Investigative Medicine, Imperial College London, Hammersmith Hospital, London, UK
Imperial College Healthcare NHS Trust, London, UK
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Imperial College Healthcare NHS Trust, London, UK
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Waljit S Dhillo
Waljit S Dhillo
Department of Investigative Medicine, Imperial College London, Hammersmith Hospital, London, UK
Imperial College Healthcare NHS Trust, London, UK
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Imperial College Healthcare NHS Trust, London, UK
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Niamh M Martin
Niamh M Martin
Department of Investigative Medicine, Imperial College London, Hammersmith Hospital, London, UK
Imperial College Healthcare NHS Trust, London, UK
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Imperial College Healthcare NHS Trust, London, UK
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patients, pituitary apoplexy was precipitated following administration of antiplatelet/anticoagulant therapy for acute coronary syndrome. Table 1 Demographics, predisposing factors and adenoma type in the patients who present with pituitary apoplexy
Marc Blondon
Marc Blondon
Division of Angiology and Hemostasis, Geneva University Hospitals and Faculty of Medicine, University of Geneva, Geneva, Switzerland
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Emmanuel Biver
Emmanuel Biver
Division of Bone Diseases, Geneva University Hospitals and Faculty of Medicine, University of Geneva, Geneva, Switzerland
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Olivia Braillard
Olivia Braillard
Division of Primary Care Medicine, Geneva University Hospitals and Faculty of Medicine, University of Geneva, Geneva, Switzerland
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Marc Righini
Marc Righini
Division of Angiology and Hemostasis, Geneva University Hospitals and Faculty of Medicine, University of Geneva, Geneva, Switzerland
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Pierre Fontana
Pierre Fontana
Division of Angiology and Hemostasis, Geneva University Hospitals and Faculty of Medicine, University of Geneva, Geneva, Switzerland
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Alessandro Casini
Alessandro Casini
Division of Angiology and Hemostasis, Geneva University Hospitals and Faculty of Medicine, University of Geneva, Geneva, Switzerland
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anticoagulant or calcium/vitamin D supplements, an active cancer (diagnosed within 5 years or treated within 2 years), renal insufficiency (eGFR <30 mL/min), a primary hyperparathyroidism, any malabsorption disease, an active inflammatory disease, a recent
Jesper Krogh
Jesper Krogh
Department of Endocrinology & Metabolism, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark
Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark
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Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark
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Peter Plomgaard
Peter Plomgaard
Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark
Department of Clinical Biochemistry, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark
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Department of Clinical Biochemistry, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark
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Ruth Frikke-Schmidt
Ruth Frikke-Schmidt
Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark
Department of Clinical Biochemistry, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark
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Department of Clinical Biochemistry, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark
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Sten Velschow
Sten Velschow
Fluisense ApS, Lillerød, Denmark
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Jesper Johannesen
Jesper Johannesen
Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark
Department of Pediatrics, Copenhagen University Hospital - Herlev & Gentofte, Copenhagen, Denmark
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Department of Pediatrics, Copenhagen University Hospital - Herlev & Gentofte, Copenhagen, Denmark
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Linda Maria Hilsted
Linda Maria Hilsted
Department of Clinical Biochemistry, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark
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Malene Schrøder
Malene Schrøder
Fluisense ApS, Lillerød, Denmark
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Ulla Feldt-Rasmussen
Ulla Feldt-Rasmussen
Department of Endocrinology & Metabolism, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark
Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark
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Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark
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could be mended by increasing the flow of anticoagulants in future trials. Importantly, no serious adverse events occurred, and blood sampling before and after insertion suggested a clinically non-significant fall in thrombocytes but otherwise no
Hong Wang
Hong Wang
Department of Endocrinology, Affiliated Hospital 2 of Nantong University and First People’s Hospital of Nantong City, Nantong, China
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Jie Cao
Jie Cao
Department of Endocrinology, Affiliated Hospital 2 of Nantong University and First People’s Hospital of Nantong City, Nantong, China
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Jian-bin Su
Jian-bin Su
Department of Endocrinology, Affiliated Hospital 2 of Nantong University and First People’s Hospital of Nantong City, Nantong, China
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Xue-qin Wang
Xue-qin Wang
Department of Endocrinology, Affiliated Hospital 2 of Nantong University and First People’s Hospital of Nantong City, Nantong, China
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Dong-mei Zhang
Dong-mei Zhang
Medical Research Center, Affiliated Hospital 2 of Nantong University, and First People’s Hospital of Nantong City, Nantong, China
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Xiao-hua Wang
Xiao-hua Wang
Department of Endocrinology, Affiliated Hospital 2 of Nantong University and First People’s Hospital of Nantong City, Nantong, China
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these insulin resistance indices were independently associated with poor outcomes of cardiovascular disease (CVD) and acute ischemic stroke ( 6 , 7 ). Antithrombin 3 (AT3), one of the most important natural anticoagulants, plays a key role in
Shenghe Luo
Shenghe Luo
College of Pharmacy, Yanbian University, Yanji, China
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Yunhui Zuo
Yunhui Zuo
Department of Physiology and Pathophysiology, College of Medicine, Yanbian University, Yanji, China
Department of Cardiology, Yanbian University Hospital, Yanji, China
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Department of Cardiology, Yanbian University Hospital, Yanji, China
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Xiaotian Cui
Xiaotian Cui
Department of Physiology and Pathophysiology, College of Medicine, Yanbian University, Yanji, China
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Meiping Zhang
Meiping Zhang
Department of Cardiology, Yanbian University Hospital, Yanji, China
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Honghua Jin
Honghua Jin
Department of Pharmacy, Yanbian University Hospital, Yanji, China
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Lan Hong
Lan Hong
Department of Physiology and Pathophysiology, College of Medicine, Yanbian University, Yanji, China
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the ET tubes containing anticoagulants (10 μL EDTA and 20 μL aprotinin per ET anticoagulant tube) for subsequent ANP assays, the heart was immediately removed at −80°C for subsequent experiments. Determination of ANP content ANP concentrations
