M Axelstad
M Axelstad
Technical University of Denmark, National Food Institute, Kongens Lyngby, Denmark
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U Hass
U Hass
Technical University of Denmark, National Food Institute, Kongens Lyngby, Denmark
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M Scholze
M Scholze
Brunel University, Uxbridge, UK
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S Christiansen
S Christiansen
Technical University of Denmark, National Food Institute, Kongens Lyngby, Denmark
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A Kortenkamp
A Kortenkamp
Brunel University, Uxbridge, UK
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J Boberg
J Boberg
Technical University of Denmark, National Food Institute, Kongens Lyngby, Denmark
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investigating how male reproduction may be influenced by developmental exposure of rats to the painkiller paracetamol or to mixtures of human relevant environmental EDCs. In addition to a therapeutically relevant dose of paracetamol, a mixture of 8 anti-androgenic
Lachlan Angus
Lachlan Angus
Department of Medicine (Austin Health), The University of Melbourne, Heidelberg, Victoria, Australia
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Shalem Leemaqz
Shalem Leemaqz
Robinson Research Institute, Adelaide Medical School, The University of Adelaide, Adelaide, South Australia
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Olivia Ooi
Olivia Ooi
Department of Medicine (Austin Health), The University of Melbourne, Heidelberg, Victoria, Australia
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Pauline Cundill
Pauline Cundill
Equinox Gender Diverse Clinic, Thorne Harbour Health, Fitzroy, Victoria, Australia
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Nicholas Silberstein
Nicholas Silberstein
Equinox Gender Diverse Clinic, Thorne Harbour Health, Fitzroy, Victoria, Australia
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Peter Locke
Peter Locke
Equinox Gender Diverse Clinic, Thorne Harbour Health, Fitzroy, Victoria, Australia
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Jeffrey D Zajac
Jeffrey D Zajac
Department of Medicine (Austin Health), The University of Melbourne, Heidelberg, Victoria, Australia
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Ada S Cheung
Ada S Cheung
Department of Medicine (Austin Health), The University of Melbourne, Heidelberg, Victoria, Australia
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characteristics. In transfeminine individuals wishing to inhibit androgenic physical characteristics, choice of anti-androgen agent is a common clinical scenario faced by patients and treating clinicians alike. Whilst both anti-androgen agents, cyproterone
Willem de Ronde
Willem de Ronde
Department of Internal Medicine, Spaarne Gasthuis, Haarlem, the Netherlands
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Diederik L Smit
Diederik L Smit
Department of Internal Medicine, Spaarne Gasthuis, Haarlem, the Netherlands
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Introduction Every now and then a clinical endocrinologist will be visited by a patient that uses anabolic androgenic steroids (AAS) or has been using them in the past. The interaction between doctor and patient may be hampered for a number of
Richard J Auchus
Richard J Auchus
Division of Metabolism, Endocrinology, and Diabetes, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA
Department of Pharmacology, University of Michigan, Ann Arbor, Michigan, USA
Veterans Affairs Medical Center, Ann Arbor, Michigan, USA
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Department of Pharmacology, University of Michigan, Ann Arbor, Michigan, USA
Veterans Affairs Medical Center, Ann Arbor, Michigan, USA
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the isolation and therapeutic use of cortisone. Hench, a rheumatologist used the anti-inflammatory properties of cortisone to treat rheumatoid arthritis, with dramatic results. Soon afterward, Thorn and Forsham treated adrenal insufficiency with
Pravik Solanki
Pravik Solanki
Faculty of Medicine, Nursing and Health Sciences, Monash University, Victoria, Australia
Alfred Health, Melbourne, Victoria, Australia
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Alfred Health, Melbourne, Victoria, Australia
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Beng Eu
Beng Eu
Prahran Market Clinic, Victoria, Australia
Department of General Practice, Melbourne Medical School, The University of Melbourne, Victoria, Australia
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Department of General Practice, Melbourne Medical School, The University of Melbourne, Victoria, Australia
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Jeremy Smith
Jeremy Smith
Faculty of Science, University of Western Australia, Perth, Australia
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Carolyn Allan
Carolyn Allan
Hudson Institute of Medical Research, Melbourne, Victoria, Australia
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Kevin Lee
Kevin Lee
Faculty of Medicine, Nursing and Health Sciences, Monash University, Victoria, Australia
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Introduction Anabolic–androgenic steroid (AAS) use is illegal if not prescribed by a medical practitioner ( 1 ). Androgens are abused predominantly by young males trying to improve sporting performance or to increase muscle mass and decrease
Nancy J Olsen
Nancy J Olsen
Division of Rheumatology, Division of Endocrinology, Diabetes, and Metabolism, College of Medicine, Milton S Hershey Medical Center, The Pennsylvania State University, Mail Code H044, 500 University Drive, Hershey, Pennsylvania 17033-0850, USA
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Ann L Benko
Ann L Benko
Division of Rheumatology, Division of Endocrinology, Diabetes, and Metabolism, College of Medicine, Milton S Hershey Medical Center, The Pennsylvania State University, Mail Code H044, 500 University Drive, Hershey, Pennsylvania 17033-0850, USA
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William J Kovacs
William J Kovacs
Division of Rheumatology, Division of Endocrinology, Diabetes, and Metabolism, College of Medicine, Milton S Hershey Medical Center, The Pennsylvania State University, Mail Code H044, 500 University Drive, Hershey, Pennsylvania 17033-0850, USA
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Introduction Androgenic gonadal steroid hormones exert effects on both human autoimmune disease and the corresponding animal models. In an experimental mouse model of human systemic lupus erythematosus, females acquire fatal renal disease while
A Daniel Bird
A Daniel Bird
Department of Biochemistry and Molecular Biology, Monash University, Melbourne, Victoria, Australia
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Spencer Greatorex
Spencer Greatorex
Department of Biochemistry and Molecular Biology, Monash University, Melbourne, Victoria, Australia
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David Reser
David Reser
Department of Physiology, Monash University, Melbourne, Victoria, Australia
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Gareth G Lavery
Gareth G Lavery
Institute of Metabolism and Systems Research, 2nd Floor IBR Tower, University of Birmingham, Birmingham, UK
Centre for Endocrinology, Diabetes and Metabolism, Birmingham Health Partners, Birmingham, UK
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Centre for Endocrinology, Diabetes and Metabolism, Birmingham Health Partners, Birmingham, UK
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Timothy J Cole
Timothy J Cole
Department of Biochemistry and Molecular Biology, Monash University, Melbourne, Victoria, Australia
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sections with a thickness of 5 μm were cut and mounted on slides, blocked with an appropriate animal serum (5%), then immunostained with donkey anti-HSD1L (sc-1004, Santa Cruz) primary antibodies overnight at 4°C. Supplementary Table 1 (see section on
Elizabeth Micks
Elizabeth Micks
Department of Obstetrics and Gynecology, Department of Research, University of Washington, Box 356460, 1959 NE Pacific Street, Seattle, Washington, USA
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Greta B Raglan
Greta B Raglan
Department of Obstetrics and Gynecology, Department of Research, University of Washington, Box 356460, 1959 NE Pacific Street, Seattle, Washington, USA
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Jay Schulkin
Jay Schulkin
Department of Obstetrics and Gynecology, Department of Research, University of Washington, Box 356460, 1959 NE Pacific Street, Seattle, Washington, USA
Department of Obstetrics and Gynecology, Department of Research, University of Washington, Box 356460, 1959 NE Pacific Street, Seattle, Washington, USA
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Department of Obstetrics and Gynecology, Department of Research, University of Washington, Box 356460, 1959 NE Pacific Street, Seattle, Washington, USA
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cyproterone acetate, have anti-androgenic and anti-mineralocorticoid activity, possibly leading to desirable non-contraceptive benefits in certain patients (65) . Most data regarding the differences between different progestins are from in vitro biochemical
Brenda Anguiano
Brenda Anguiano
Departamento de Neurobiología Celular y Molecular, Instituto de Neurobiología, Universidad Nacional Autónoma de México, Campus Juriquilla, Querétaro, México
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Carlos Montes de Oca
Carlos Montes de Oca
Departamento de Neurobiología Celular y Molecular, Instituto de Neurobiología, Universidad Nacional Autónoma de México, Campus Juriquilla, Querétaro, México
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Evangelina Delgado-González
Evangelina Delgado-González
Departamento de Neurobiología Celular y Molecular, Instituto de Neurobiología, Universidad Nacional Autónoma de México, Campus Juriquilla, Querétaro, México
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Carmen Aceves
Carmen Aceves
Departamento de Neurobiología Celular y Molecular, Instituto de Neurobiología, Universidad Nacional Autónoma de México, Campus Juriquilla, Querétaro, México
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inhibits the androgenic response in LNCaP cells and reduces the invasive capacity of DU145 and PC-3 cells ( 7 ). These antitumor effects of CRYM/T3 have been explained by a reduction of T3 binding to nuclear receptors ( 7 ). Moreover, it has been proposed
Yen Kheng Tan
Yen Kheng Tan
Duke-NUS Medical School, SingHealth, Singapore, Singapore
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Yu Heng Kwan
Yu Heng Kwan
Department of Internal Medicine, Singapore General Hospital, Singapore, Singapore
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David Choon Liang Teo
David Choon Liang Teo
Department of Psychological Medicine, Changi General Hospital, Singapore, Singapore
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Marieke Velema
Marieke Velema
Division of Endocrinology, Department of Internal Medicine, Radboud University Medical Centre, Nijmegen, The Netherlands
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Jaap Deinum
Jaap Deinum
Division of Vascular Medicine, Department of Internal Medicine, Radboud University Medical Centre, Nijmegen, The Netherlands
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Pei Ting Tan
Pei Ting Tan
Department of Clinical Trials Research Unit, Changi General Hospital, Singapore, Singapore
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Meifen Zhang
Meifen Zhang
Department of Endocrinology, Changi General Hospital, Singapore, Singapore
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Joan Joo Ching Khoo
Joan Joo Ching Khoo
Department of Endocrinology, Changi General Hospital, Singapore, Singapore
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Wann Jia Loh
Wann Jia Loh
Department of Endocrinology, Changi General Hospital, Singapore, Singapore
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Linsey Gani
Linsey Gani
Department of Endocrinology, Changi General Hospital, Singapore, Singapore
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Thomas F J King
Thomas F J King
Department of Endocrinology, Changi General Hospital, Singapore, Singapore
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Eberta Jun Hui Tan
Eberta Jun Hui Tan
Department of Endocrinology, Changi General Hospital, Singapore, Singapore
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Shui Boon Soh
Shui Boon Soh
Department of Endocrinology, Changi General Hospital, Singapore, Singapore
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Vanessa Shu Chuan Au
Vanessa Shu Chuan Au
Department of Endocrinology, Changi General Hospital, Singapore, Singapore
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Tunn Lin Tay
Tunn Lin Tay
Department of Endocrinology, Changi General Hospital, Singapore, Singapore
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Lily Mae Quevedo Dacay
Lily Mae Quevedo Dacay
Department of Endocrinology, Changi General Hospital, Singapore, Singapore
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Keng Sin Ng
Keng Sin Ng
Department of Diagnostic Radiology, Changi General Hospital, Singapore, Singapore
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Kang Min Wong
Kang Min Wong
Department of Diagnostic Radiology, Changi General Hospital, Singapore, Singapore
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Andrew Siang Yih Wong
Andrew Siang Yih Wong
Department of Surgery, Changi General Hospital, Singapore, Singapore
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Foo Cheong Ng
Foo Cheong Ng
Department of Urology, Changi General Hospital, Singapore, Singapore
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Tar Choon Aw
Tar Choon Aw
Department of Laboratory Medicine, Changi General Hospital, Singapore, Singapore
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Yvonne Hui Bin Chan
Yvonne Hui Bin Chan
Duke-NUS Medical School, SingHealth, Singapore, Singapore
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Khim Leng Tong
Khim Leng Tong
Department of Cardiology, Changi General Hospital, Singapore, Singapore
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Sheldon Shao Guang Lee
Sheldon Shao Guang Lee
Department of Cardiology, Changi General Hospital, Singapore, Singapore
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Siang Chew Chai
Siang Chew Chai
Department of Cardiology, Changi General Hospital, Singapore, Singapore
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Troy Hai Kiat Puar
Troy Hai Kiat Puar
Department of Endocrinology, Changi General Hospital, Singapore, Singapore
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anti-androgenic side effects of MR antagonists. Patient-perceived health outcomes have an increasingly important role in healthcare. One of the most widely used questionnaires is the RAND-36, a generic HRQoL questionnaire which captures multiple
