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course with the alpha-glucosidase inhibitor, acarbose, on GM profiles (evaluated by 16S rRNA gene-based high-throughput sequencing) in Caucasian individuals with metformin-treated T2D. Materials and methods Ethics and study approvals This
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enteral glucose absorption (alpha-glucosidase inhibitors) and increasing renal glucose excretion (SGLT-2 inhibitors). When mono-drug therapy fails, various combinations of drug administration are required for different clinical conditions. In worsened
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inhibits the androgenic response in LNCaP cells and reduces the invasive capacity of DU145 and PC-3 cells ( 7 ). These antitumor effects of CRYM/T3 have been explained by a reduction of T3 binding to nuclear receptors ( 7 ). Moreover, it has been proposed
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kinase; IκB, nuclear factor-kappaB inhibitor alpha; NIK, Nf-κB inducing kinase; RTK, receptor tyrosine kinases; TNF, tumor necrosis factor; TRAF2, TNF receptor-associated factor 2; RIP1, receptor-interacting protein1; MEK, MAPK kinase; MEKK, MEK kinase
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-lowering therapies were acquired by searching the electronic medical record system and then were categorized into subclasses, which included insulin injections, sulfonylureas (SUs), metformin, thiazolidinediones (TZDs), α-glucosidase inhibitors (AGIs), dipeptidyl
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MA . Post-gastric-bypass hypoglycemia successfully treated with alpha-glucosidase inhibitor therapy . Endocrine Practice 2013 19 511 – 514 . ( https://doi.org/10.4158/EP12281.RA ) 102 Cadegiani FA & Silva OS . Acarbose promotes remission of
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of hepatic glucose cycling in glucose-intolerant or NIDDM patients . Diabetes 1991 40 73 – 81 . ( doi:10.2337/diab.40.1.73 ) 2 Holman RR. Assessing the potential for alpha-glucosidase inhibitors in prediabetic states. Diabetes Research
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.79 ± 5.13 Medications Sulfnylurea N.A. N.A. 54% Biguanide N.A. N.A. 55% α-glucosidase inhibitor N.A. N.A. 17% Glinide N.A. N.A. 3% Pioglitazone N.A. N.A. 22
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) OADs included dipeptidyl peptidase 4 inhibitors, sulfonylureas, meglitinides, thiazolidinediones and alpha-glucosidase inhibitors. Only two patients, both in the C2402 study, received a GLP-1 receptor agonist (liraglutide); these two patients were not