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Feifei Shao Department of Endocrinology, Gansu Provincial Hospital, Lanzhou, Gansu, China
Clinical Research Center for Metabolic Disease, Gansu Province, Lanzhou, Gansu, China
The First School of Clinical Medicine, Lanzhou University, Lanzhou, Gansu, China

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Xinxin Hu Clinical Research Center for Metabolic Disease, Gansu Province, Lanzhou, Gansu, China
The First School of Clinical Medicine, Lanzhou University, Lanzhou, Gansu, China

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Jiayu Li Clinical Research Center for Metabolic Disease, Gansu Province, Lanzhou, Gansu, China
The First School of Clinical Medicine, Lanzhou University, Lanzhou, Gansu, China

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Bona Bai Clinical Research Center for Metabolic Disease, Gansu Province, Lanzhou, Gansu, China
The First School of Clinical Medicine, Lanzhou University, Lanzhou, Gansu, China

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Limin Tian Department of Endocrinology, Gansu Provincial Hospital, Lanzhou, Gansu, China
Clinical Research Center for Metabolic Disease, Gansu Province, Lanzhou, Gansu, China
The First School of Clinical Medicine, Lanzhou University, Lanzhou, Gansu, China

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Introduction The growing aging population and the increasing prevalence of type 2 diabetes mellitus (T2DM) have become a substantial concern for healthcare systems worldwide. A study reported that the prevalence of diabetes peaks at the age of

Article Type:
Research Article
Collections:
Metabolic Syndrome and Diabetes
DOI:
https://doi.org/10.1530/EC-23-0212
Volume/Issue:
Volume 12: Issue 12
Open access
Andrew R Dismukes Department of Human Development and Family Studies, Iowa State University, Ames, Iowa, USA
Tulane University School of Medicine, Department of Psychiatry, Division of Child and Adolescent Psychiatry, Tulane University, New Orleans, Louisiana, USA

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Vanessa J Meyer Department of Human Development and Family Studies, Iowa State University, Ames, Iowa, USA
Tulane University School of Medicine, Department of Psychiatry, Division of Child and Adolescent Psychiatry, Tulane University, New Orleans, Louisiana, USA

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Elizabeth A Shirtcliff Department of Human Development and Family Studies, Iowa State University, Ames, Iowa, USA

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Katherine P Theall Tulane University School of Medicine, Department of Psychiatry, Division of Child and Adolescent Psychiatry, Tulane University, New Orleans, Louisiana, USA

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Kyle C Esteves Tulane University School of Medicine, Department of Psychiatry, Division of Child and Adolescent Psychiatry, Tulane University, New Orleans, Louisiana, USA

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Stacy S Drury Tulane University School of Medicine, Department of Psychiatry, Division of Child and Adolescent Psychiatry, Tulane University, New Orleans, Louisiana, USA

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Introduction Dehydroepiandrosterone (DHEA) is a steroid hormone that is sometimes called the ‘anti-aging hormone’ because of ts protective effects on memory, neuronal growth, and neuronal activity ( 1 ). DHEA is produced both centrally, as a

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-16-0007
Volume/Issue:
Volume 5: Issue 3
Open access
W N H Koek Department of Internal Medicine, Erasmus MC, University Medical Center, Rotterdam, the Netherlands

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N Campos-Obando Department of Internal Medicine, Erasmus MC, University Medical Center, Rotterdam, the Netherlands

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B C J van der Eerden Department of Internal Medicine, Erasmus MC, University Medical Center, Rotterdam, the Netherlands

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Y B de Rijke Department of Clinical Chemistry, Erasmus MC, University Medical Center, Rotterdam, the Netherlands

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M A Ikram Department of Epidemiology, Erasmus MC, Rotterdam, the Netherlands

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A G Uitterlinden Department of Internal Medicine, Erasmus MC, University Medical Center, Rotterdam, the Netherlands
Department of Epidemiology, Erasmus MC, Rotterdam, the Netherlands

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J P T M van Leeuwen Department of Internal Medicine, Erasmus MC, University Medical Center, Rotterdam, the Netherlands

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M C Zillikens Department of Internal Medicine, Erasmus MC, University Medical Center, Rotterdam, the Netherlands

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levels compared to men above 45 years of age. Adjustment for serum testosterone levels diminished the sex differences in serum phosphate but not serum calcium levels, while adjustment for serum estradiol did not consistently influence sex differences in

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-20-0509
Volume/Issue:
Volume 10: Issue 3
Open access
Souad Daamouch Department of Medicine III and Center for Healthy Aging, Technische Universität Dresden, Dresden, Germany

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Sylvia Thiele Department of Medicine III and Center for Healthy Aging, Technische Universität Dresden, Dresden, Germany

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Lorenz Hofbauer Department of Medicine III and Center for Healthy Aging, Technische Universität Dresden, Dresden, Germany

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Martina Rauner Department of Medicine III and Center for Healthy Aging, Technische Universität Dresden, Dresden, Germany

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dietary habits, excess caloric intake, and low physical activity ( 4 , 5 ). Although new technologies and medical advances have improved life expectancy over the years, reduced quality of life paradoxically persists in the aging population, driven mostly

Article Type:
Research Article
Collections:
Bone and Mineral Metabolism
DOI:
https://doi.org/10.1530/EC-23-0251
Volume/Issue:
Volume 12: Issue 11
Open access
Charissa van Zwol-Janssens Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynaecology, Erasmus University Medical Center, Rotterdam, the Netherlands

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Aglaia Hage Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynaecology, Erasmus University Medical Center, Rotterdam, the Netherlands

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Kim van der Ham Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynaecology, Erasmus University Medical Center, Rotterdam, the Netherlands

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Birgitta K Velthuis Department of Radiology, University Medical Center Utrecht, University of Utrecht, Utrecht, the Netherlands

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Ricardo P J Budde Department of Radiology and Nuclear Medicine, Erasmus University Medical Center, Rotterdam, the Netherlands

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Maria P H Koster Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynaecology, Erasmus University Medical Center, Rotterdam, the Netherlands

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Arie Franx Department of Obstetrics and Gynaecology, Erasmus University Medical Center, Rotterdam, the Netherlands

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Bart C J M Fauser Department of Reproductive Medicine and Gynaecology, University Medical Center Utrecht & University of Utrecht, Utrecht, the Netherlands

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Eric Boersma Department of Cardiology, Erasmus University Medical Center, Rotterdam, the Netherlands

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Daniel Bos Department of Radiology and Nuclear Medicine, Erasmus University Medical Center, Rotterdam, the Netherlands
Department of Epidemiology, Erasmus University Medical Center, Rotterdam, the Netherlands

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Joop S E Laven Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynaecology, Erasmus University Medical Center, Rotterdam, the Netherlands

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Yvonne V Louwers Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynaecology, Erasmus University Medical Center, Rotterdam, the Netherlands

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the CREW consortium
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the CREW consortium

risk for failure to attain peak bone mass or for early loss of BD, due to estrogen deficiency at an early age ( 1 , 2 , 3 , 4 , 5 ). Consequently, women with POI are advised to use hormone replacement therapy (HRT) ( 6 ). In contrast to POI, the

Article Type:
Research Article
Collections:
Reproduction
DOI:
https://doi.org/10.1530/EC-23-0166
Volume/Issue:
Volume 12: Issue 11
Open access
Lawrence D Hayes Active Ageing Research Group, Department of Medical and Sport Sciences, University of Cumbria, Lancaster, UK

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Peter Herbert School of Sport, Health and Outdoor Education, Trinity Saint David, University of Wales, Carmarthen, UK

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Nicholas F Sculthorpe Institute of Clinical Exercise and Health Science, University of the West of Scotland, Hamilton, UK

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Fergal M Grace Faculty of Health, Federation University, Victoria, Australia

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Introduction Testosterone is a sex steroid hormone with profound influence on various tissues ( 1 , 2 , 3 ). The precipitous decline in systemic testosterone with age is well described ( 4 ). Additionally, sex hormone-binding globulin (SHBG

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-17-0082
Volume/Issue:
Volume 6: Issue 5
Open access
Sandra N Slagter Department of Endocrinology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands

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Robert P van Waateringe Department of Endocrinology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands

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André P van Beek Department of Endocrinology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands

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Melanie M van der Klauw Department of Endocrinology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands

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Bruce H R Wolffenbuttel Department of Endocrinology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands

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Jana V van Vliet-Ostaptchouk Department of Endocrinology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands

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across different age groups, is unclear. Previously, we observed that besides abdominal obesity, elevated blood pressure was the most common abnormality contributing to the prevalence of MetS, within all BMI classes ( 6 , 7 ). Elevated blood pressure

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-17-0011
Volume/Issue:
Volume 6: Issue 4
Open access
Sebastião Freitas de Medeiros Department of Gynecology and Obstetrics, Medical School, Federal University of Mato Grosso, Cuiabá, Mato Grosso, Brazil
Tropical Institute of Reproductive Medicine, Cuiabá, Mato Grosso, Brazil

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Márcia Marly Winck Yamamoto Tropical Institute of Reproductive Medicine, Cuiabá, Mato Grosso, Brazil

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Matheus Antônio Souto de Medeiros Tropical Institute of Reproductive Medicine, Cuiabá, Mato Grosso, Brazil

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Bruna Barcelo Barbosa Tropical Institute of Reproductive Medicine, Cuiabá, Mato Grosso, Brazil

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José Maria Soares Junior Disciplina de Ginecologia, Departamento de Obstetrícia e Ginecologia, Hospital das Clínicas, Faculdade de Medicina da Universidade de São Paulo, São Paulo, São Paulo, Brazil

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Edmund Chada Baracat Disciplina de Ginecologia, Departamento de Obstetrícia e Ginecologia, Hospital das Clínicas, Faculdade de Medicina da Universidade de São Paulo, São Paulo, São Paulo, Brazil

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Introduction Polycystic ovary syndrome (PCOS) has a prevalence ranging from 5 to 20% in women of reproductive age, depending on the population and criteria used for making a definitive diagnosis ( 1 , 2 ). The use of ultrasound may increase

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-19-0496
Volume/Issue:
Volume 9: Issue 2
Open access
Andrea Mazurat Section of Surgical Oncology, Department of Surgery, CancerCare Manitoba, University of Manitoba, GF440 A, 820 Sherbrook Street, Winnipeg, Manitoba, Canada R3A 1R9

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Andrea Torroni Section of Surgical Oncology, Department of Surgery, CancerCare Manitoba, University of Manitoba, GF440 A, 820 Sherbrook Street, Winnipeg, Manitoba, Canada R3A 1R9

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Jane Hendrickson-Rebizant Section of Surgical Oncology, Department of Surgery, CancerCare Manitoba, University of Manitoba, GF440 A, 820 Sherbrook Street, Winnipeg, Manitoba, Canada R3A 1R9

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Harbinder Benning Section of Surgical Oncology, Department of Surgery, CancerCare Manitoba, University of Manitoba, GF440 A, 820 Sherbrook Street, Winnipeg, Manitoba, Canada R3A 1R9

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Richard W Nason Section of Surgical Oncology, Department of Surgery, CancerCare Manitoba, University of Manitoba, GF440 A, 820 Sherbrook Street, Winnipeg, Manitoba, Canada R3A 1R9

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K Alok Pathak Section of Surgical Oncology, Department of Surgery, CancerCare Manitoba, University of Manitoba, GF440 A, 820 Sherbrook Street, Winnipeg, Manitoba, Canada R3A 1R9

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-risk and low-risk patients on the basis of the tumor and patient characteristics. Several factors have been associated with aggressive behavior in WDTC, including the age at diagnosis, the gender of the patient, the size and extension of the primary tumor

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-13-0056
Volume/Issue:
Volume 2: Issue 3
Open access
Ferdinand Roelfsema Department of Internal Medicine, Leiden University Medical Center, Leiden, The Netherlands

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Diana van Heemst Department of Internal Medicine, Section Gerontology and Geriatrics, Leiden University Medical Center, Leiden, The Netherlands

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Ali Iranmanesh Endocrine Section, Medical Service, Salem Veterans Affairs Medical Center, Salem, Virginia, USA

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Paul Takahashi Primary Care Internal Medicine, Mayo Clinic, Rochester, Minnesota, USA

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Rebecca Yang Endocrine Research Unit, Mayo Medical and Graduate Schools, Clinical Translational Research Center, Mayo Clinic, Rochester, Minnesota, USA

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Johannes D Veldhuis Endocrine Research Unit, Mayo Medical and Graduate Schools, Clinical Translational Research Center, Mayo Clinic, Rochester, Minnesota, USA

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on the influence of age, sex and body mass on HPA dynamics are conflicting ( 3 , 4 , 5 , 6 , 10 , 11 , 12 , 13 , 14 , 15 , 16 , 17 , 18 ). The small size of most cohorts evaluated to date, the narrow age and BMI ranges encompassed and the

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-17-0160
Volume/Issue:
Volume 6: Issue 7
Open access