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Angela Köninger, Antonella Iannaccone, Ensar Hajder, Mirjam Frank, Boerge Schmidt, Ekkehard Schleussner, Rainer Kimmig, Alexandra Gellhaus and Hans Dieplinger

research. Since only scarce information is available concerning the preconceptional risk determination of pregnancy complications in PCOS patients, we here focus on afamin, an easily determinable biomarker that may indicate IR in pre-pregnant PCOS

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Angela Köninger, Philippos Edimiris, Laura Koch, Antje Enekwe, Claudia Lamina, Sabine Kasimir-Bauer, Rainer Kimmig and Hans Dieplinger

)-inhibiting parameter (11) . The previously described vitamin E-binding protein afamin may play a role in oxidative stress-related anti-apoptotic cellular processes (12) . Vitamin E is an important anti-oxidant and protects from oxidative stress. Afamin was

Open access

Gudmundur Johannsson, Martin Bidlingmaier, Beverly M K Biller, Margaret Boguszewski, Felipe F Casanueva, Philippe Chanson, Peter E Clayton, Catherine S Choong, David Clemmons, Mehul Dattani, Jan Frystyk, Ken Ho, Andrew R Hoffman, Reiko Horikawa, Anders Juul, John J Kopchick, Xiaoping Luo, Sebastian Neggers, Irene Netchine, Daniel S Olsson, Sally Radovick, Ron Rosenfeld, Richard J Ross, Katharina Schilbach, Paulo Solberg, Christian Strasburger, Peter Trainer, Kevin C J Yuen, Kerstin Wickstrom, Jens O L Jorgensen and on behalf of the Growth Hormone Research Society

and 9, vascular endothelial growth factor, isoforms of apolipoprotein A-1 and haptoglobin and afamin have been identified ( 39 , 40 , 41 ). Their usefulness as biomarkers should be established in future studies. GH doping detection strategies have