Rafaella Sales de Freitas
Rafaella Sales de Freitas
Departamento de Psicobiologia, Universidade Federal de São Paulo, São Paulo, Brazil
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Thiago F A França
Thiago F A França
Departamento de Psicobiologia, Universidade Federal de São Paulo, São Paulo, Brazil
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Sabine Pompeia
Sabine Pompeia
Departamento de Psicobiologia, Universidade Federal de São Paulo, São Paulo, Brazil
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Introduction Adolescence is a period of life marked by an interconnected set of social, cognitive, psycho-emotional, and morphophysiological changes ( 1 ). The morphophysiological aspects of adolescent development are related to puberty, which
Johanna Öberg
Johanna Öberg
Tromso Endocrine Research Group, Department of Clinical Medicine, UiT The Arctic University of Norway, Tromso, Norway
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Rolf Jorde
Rolf Jorde
Tromso Endocrine Research Group, Department of Clinical Medicine, UiT The Arctic University of Norway, Tromso, Norway
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Yngve Figenschau
Yngve Figenschau
Tromso Endocrine Research Group, Department of Clinical Medicine, UiT The Arctic University of Norway, Tromso, Norway
Diagnostic Clinic, University Hospital of North Norway, Tromso, Norway
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Diagnostic Clinic, University Hospital of North Norway, Tromso, Norway
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Per Medbøe Thorsby
Per Medbøe Thorsby
Hormone Laboratory, Department of Medical Biochemistry and Biochemical Endocrinology and Metabolism Research Group, Oslo University Hospital, Aker, Oslo, Norway
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Sandra Rinne Dahl
Sandra Rinne Dahl
Hormone Laboratory, Department of Medical Biochemistry and Biochemical Endocrinology and Metabolism Research Group, Oslo University Hospital, Aker, Oslo, Norway
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Anne Winther
Anne Winther
Division of Neurosciences, Orthopedics and Rehabilitation Services, University Hospital of North Norway, Tromso, Norway
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Guri Grimnes
Guri Grimnes
Tromso Endocrine Research Group, Department of Clinical Medicine, UiT The Arctic University of Norway, Tromso, Norway
Division of Internal Medicine, University Hospital of North Norway, Tromso, Norway
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Division of Internal Medicine, University Hospital of North Norway, Tromso, Norway
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to 25(OH)D differed by CHC use, presented in scatterplots. Methods Study population Fit Futures is a population-based, longitudinal study of the transition from adolescence to adulthood ongoing in Tromsø and Balsfjord municipality in North
Rebeca Esquivel-Zuniga
Rebeca Esquivel-Zuniga
Department of Pediatrics, University of Virginia, Charlottesville, Virginia, USA
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Alan D Rogol
Alan D Rogol
Department of Pediatrics, University of Virginia, Charlottesville, Virginia, USA
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. ( https://doi.org/10.1159/000058094 ) 2 Dwyer AA Phan-Hug F Hauschild M Elowe-Gruau E & Pitteloud N . Transition in endocrinology: Hypogonadism in adolescence . European Journal of Endocrinology 2015 173 R15 – R24 . ( https://doi.org/10
Karolien Van De Maele
Karolien Van De Maele
Division of Pediatric Endocrinology, KidZ Health Castle, UZ Brussel, Vrije Universiteit Brussel, Brussels, Belgium
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Jean De Schepper
Jean De Schepper
Division of Pediatric Endocrinology, KidZ Health Castle, UZ Brussel, Vrije Universiteit Brussel, Brussels, Belgium
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Jesse Vanbesien
Jesse Vanbesien
Division of Pediatric Endocrinology, KidZ Health Castle, UZ Brussel, Vrije Universiteit Brussel, Brussels, Belgium
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Monique Van Helvoirt
Monique Van Helvoirt
Zeepreventorium, De Haan, Belgium
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Ann De Guchtenaere
Ann De Guchtenaere
Zeepreventorium, De Haan, Belgium
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Inge Gies
Inge Gies
Division of Pediatric Endocrinology, KidZ Health Castle, UZ Brussel, Vrije Universiteit Brussel, Brussels, Belgium
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Background
Vitamin D deficiency is common in obese adolescents and a risk factor for insulin resistance. We investigated if prevailing serum 25-OH vitamin D might predict the body fat loss in a group of obese adolescents undergoing a residential weight loss program.
Methods
In 92 (35 male) obese adolescents (aged 10.6–19 years) undergoing a residential weight loss program in Belgium, fasting serum 25-OH vitamin D (25-OH-D), insulin, glucose and lipid levels were measured and body composition was assessed by dual-energy X-ray absorptiometry (DXA).
Results
Baseline median (range) serum 25-OH-D level was 17.7 µg/L (3.8–41.8). In total, 55 adolescents had a serum 25-OH-D below 20 µg/L. In 31 adolescents with a low baseline 25-OH-D level, median increase in serum 25-OH-D was 2.4 µg/L (−4.2 to 7.2) after 10 months. This resulted in normal 25-OH-D levels in seven adolescents, whereas median BMI decreased with 1.0 SDS and body fat percentage diminished with 9.9%. Obese adolescents with or without a 25-OH-D level below or above 20 µg/L at baseline had similar changes in body weight, BMI SDS, body fat percentage and body fat mass at the end of the program. The change in serum 25-OH-D did not correlate with change in serum insulin, BMI SDS or body fat percentage and body fat mass.
Conclusion
Vitamin D deficiency was present in 55 out of 92 obese adolescents at the start of the summer. Serum 25-OH-D concentration did not predict changes in body fat loss after a residential weight loss program.
Nicola Tufton
Nicola Tufton
Department of Endocrinology, St Bartholomew’s Hospital, Barts Health NHS Trust, London, UK
Centre for Endocrinology, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK
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Centre for Endocrinology, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK
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Lucy Shapiro
Lucy Shapiro
Centre for Endocrinology, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK
Department of Paediatric Endocrinology, Royal London Hospital, Barts Health NHS Trust, London, UK
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Department of Paediatric Endocrinology, Royal London Hospital, Barts Health NHS Trust, London, UK
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Anju Sahdev
Anju Sahdev
Department of Radiology, St Bartholomew’s Hospital, Barts Health NHS Trust, London, UK
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Ajith V Kumar
Ajith V Kumar
North East Thames Regional Genetics Service, Great Ormond Street Hospital, London, UK
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Lee Martin
Lee Martin
Department of Paediatric Endocrinology, Royal London Hospital, Barts Health NHS Trust, London, UK
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William M Drake
William M Drake
Department of Endocrinology, St Bartholomew’s Hospital, Barts Health NHS Trust, London, UK
Centre for Endocrinology, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK
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Centre for Endocrinology, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK
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Scott A Akker
Scott A Akker
Department of Endocrinology, St Bartholomew’s Hospital, Barts Health NHS Trust, London, UK
Centre for Endocrinology, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK
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Centre for Endocrinology, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK
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Helen L Storr
Helen L Storr
Centre for Endocrinology, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK
Department of Paediatric Endocrinology, Royal London Hospital, Barts Health NHS Trust, London, UK
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Department of Paediatric Endocrinology, Royal London Hospital, Barts Health NHS Trust, London, UK
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recent new information regarding the risks of radiation exposure in young patients ( 10 ). Paediatric index cases were diagnosed with a PCC or PGL in childhood or adolescence (aged <20 years) between 1975 and 2011. Index cases presented to their local
Nella Augusta Greggio
Nella Augusta Greggio
Endocrinology and Adolescence Unit, Department of Woman and Child Health, University of Padova, Padova, Italy
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Elisa Rossi
Elisa Rossi
CINECA – Interuniversity Consortium (Health Service), Bologna, Italy
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Silvia Calabria
Silvia Calabria
CORE srl – Collaborative Outcome Research, Bologna, Italy
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Alice Meneghin
Alice Meneghin
Endocrinology and Adolescence Unit, Department of Woman and Child Health, University of Padova, Padova, Italy
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Joaquin Gutierrez de Rubalcava
Joaquin Gutierrez de Rubalcava
Endocrinology and Adolescence Unit, Department of Woman and Child Health, University of Padova, Padova, Italy
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Carlo Piccinni
Carlo Piccinni
CORE srl – Collaborative Outcome Research, Bologna, Italy
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Antonella Pedrini
Antonella Pedrini
CORE srl – Collaborative Outcome Research, Bologna, Italy
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. Endocrine disorders in childhood and adolescence. Natural history of subclinical hypothyroidism in children and adolescents and potential effects of replacement therapy: a review . European Journal of Endocrinology 2012 168 R1 – R11 . ( doi:10
Supitcha Patjamontri
Supitcha Patjamontri
Developmental Endocrinology Research Group, University of Glasgow, Royal Hospital for Children, Glasgow, UK
Division of Endocrinology and Metabolism, Department of Pediatrics, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand
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Division of Endocrinology and Metabolism, Department of Pediatrics, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand
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Alexander Spiers
Alexander Spiers
MRC Centre for Environment and Health, Imperial College London, London, UK
NIHR Health Protection Research Unit on Chemical Radiation Threats and Hazards, Imperial College London, London, UK
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NIHR Health Protection Research Unit on Chemical Radiation Threats and Hazards, Imperial College London, London, UK
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Rachel B Smith
Rachel B Smith
MRC Centre for Environment and Health, Imperial College London, London, UK
NIHR Health Protection Research Unit on Chemical Radiation Threats and Hazards, Imperial College London, London, UK
National Institute for Health Research (NIHR) Health Protection Research Unit in Environmental Exposures and Health, Imperial College London, London, UK
Mohn Centre for Children’s Health and Wellbeing, Imperial College London, London, UK
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NIHR Health Protection Research Unit on Chemical Radiation Threats and Hazards, Imperial College London, London, UK
National Institute for Health Research (NIHR) Health Protection Research Unit in Environmental Exposures and Health, Imperial College London, London, UK
Mohn Centre for Children’s Health and Wellbeing, Imperial College London, London, UK
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Chen Shen
Chen Shen
MRC Centre for Environment and Health, Imperial College London, London, UK
NIHR Health Protection Research Unit on Chemical Radiation Threats and Hazards, Imperial College London, London, UK
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NIHR Health Protection Research Unit on Chemical Radiation Threats and Hazards, Imperial College London, London, UK
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Jo Adaway
Jo Adaway
Department of Clinical Biochemistry, Manchester University NHS Foundation Trust, Manchester Academic Health Science Centre, The University of Manchester, Manchester, UK
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Brian G Keevil
Brian G Keevil
Department of Clinical Biochemistry, Manchester University NHS Foundation Trust, Manchester Academic Health Science Centre, The University of Manchester, Manchester, UK
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Mireille B Toledano
Mireille B Toledano
MRC Centre for Environment and Health, Imperial College London, London, UK
NIHR Health Protection Research Unit on Chemical Radiation Threats and Hazards, Imperial College London, London, UK
National Institute for Health Research (NIHR) Health Protection Research Unit in Environmental Exposures and Health, Imperial College London, London, UK
Mohn Centre for Children’s Health and Wellbeing, Imperial College London, London, UK
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NIHR Health Protection Research Unit on Chemical Radiation Threats and Hazards, Imperial College London, London, UK
National Institute for Health Research (NIHR) Health Protection Research Unit in Environmental Exposures and Health, Imperial College London, London, UK
Mohn Centre for Children’s Health and Wellbeing, Imperial College London, London, UK
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S Faisal Ahmed
S Faisal Ahmed
Developmental Endocrinology Research Group, University of Glasgow, Royal Hospital for Children, Glasgow, UK
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0954579403000233 ) 13 Foshee VA Ennett ST Bauman KE Granger DA Benefield T Suchindran C Hussong AM Karriker-Jaffe KJ & Durant RH . A test of biosocial models of adolescent cigarette and alcohol involvement . Journal of Early Adolescence 2007
Anita Hokken-Koelega
Anita Hokken-Koelega
Erasmus University Medical Centre, Rotterdam, The Netherlands
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Aart-Jan van der Lely
Aart-Jan van der Lely
Erasmus University Medical Centre, Rotterdam, The Netherlands
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Berthold Hauffa
Berthold Hauffa
University Children’s Hospital, Essen, Germany
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Gabriele Häusler
Gabriele Häusler
Medical University and General Hospital of Vienna, Vienna, Austria
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Gudmundur Johannsson
Gudmundur Johannsson
Sahlgrenska University Hospital, Göteborg, Sweden
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Mohamad Maghnie
Mohamad Maghnie
Istituto Giannina Gaslini, University of Genova, Genova, Italy
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Jesús Argente
Jesús Argente
Hospital Infantil Universitario Niño Jesús, Madrid, Spain
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Jean DeSchepper
Jean DeSchepper
University Hospital Brussels, Brussels, Belgium
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Helena Gleeson
Helena Gleeson
Queen Elizabeth Hospital, Birmingham, UK
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John W Gregory
John W Gregory
Cardiff University School of Medicine, Cardiff, UK
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Charlotte Höybye
Charlotte Höybye
Department of Molecular Medicine and Surgery, Karolinska Institute and Department of Endocrinology, Metabolism and Diabetology, Karolinska University Hospital, Stockholm, Sweden
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Fahrettin Keleştimur
Fahrettin Keleştimur
Department of Endocrinology, School of Medicine, Erciyes University, Kayseri, Turkey
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Anton Luger
Anton Luger
Sahlgrenska University Hospital, Göteborg, Sweden
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Hermann L Müller
Hermann L Müller
Department of Pediatrics, Klinikum Oldenburg, Medical Campus University Oldenburg, Oldenburg, Germany
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Sebastian Neggers
Sebastian Neggers
University Children’s Hospital, Essen, Germany
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Vera Popovic-Brkic
Vera Popovic-Brkic
Belgrade University School of Medicine, Belgrade, Serbia
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Eleonora Porcu
Eleonora Porcu
University of Bologna, Bologna, Italy
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Lars Sävendahl
Lars Sävendahl
Department of Women’s and Children’s Health, Karolinska Institutet, and Pediatric Endocrinology Unit, Karolinska University Hospital, Stockholm, Sweden
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Stephen Shalet
Stephen Shalet
The Christie Hospital, Manchester, UK
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Bessie Spiliotis
Bessie Spiliotis
University of Patras School of Medicine, Patras, Greece
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Maithé Tauber
Maithé Tauber
Hôpital des Enfants, Toulouse, France
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Introduction Monumental changes in human development occur during adolescence. Teens undergo a period of physical growth and sexual maturation, and pronounced cognitive development, and are eagerly forming their own identities to achieve
Christine Poitou
Christine Poitou
Assistance Publique-Hôpitaux de Paris, Centre de référence Maladies Rares (PRADORT, Syndrome de Prader-Willi et autres formes rares d’obésité avec troubles du comportement alimentaire), Service de Nutrition, Hôpital Pitié-Salpêtrière, Paris, France
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Anthony Holland
Anthony Holland
Department of Psychiatry, University of Cambridge, UK
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Charlotte Höybye
Charlotte Höybye
Department of Endocrinology and Department of Molecular Medicine and Surgery, Karolinska University Hospital and Karolinska Institute, Stockholm, Sweden
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Laura C G de Graaff
Laura C G de Graaff
Center for Adults with Rare Genetic Syndromes, Department of Internal Medicine, Division of Endocrinology, Erasmus Medical Center, University Medical Center Rotterdam, Rotterdam, The Netherlands
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Sandrine Bottius
Sandrine Bottius
Assistance Publique-Hôpitaux de Paris, Centre de référence Maladies Rares (PRADORT, Syndrome de Prader-Willi et autres formes rares d’obésité avec troubles du comportement alimentaire), Service de Nutrition, Hôpital Pitié-Salpêtrière, Paris, France
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Berit Otterlei
Berit Otterlei
Landsforeningen for Prader-Willis Syndrom Hiltonåsen, Slependen, Norway
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Maithé Tauber
Maithé Tauber
Centre de référence Maladies Rares (PRADORT, Syndrome de Prader-Willi et autres formes rares d’obésité avec troubles du comportement alimentaire), Service d’Endocrinologie, Obésités, Maladies Osseuses, Génétique et Gynécologie Médicale, Hôpital des Enfants, Toulouse, France
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adolescents in their disease and also of parents in the transition process. The transition of individuals with PWS from adolescence to adult life is particularly challenging for medical care not only because of multiple comorbidities and specific skills
Hans Valdemar López Krabbe
Hans Valdemar López Krabbe
Department of Growth and Reproduction, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark
International Centre for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark
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International Centre for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark
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Jørgen Holm Petersen
Jørgen Holm Petersen
Department of Growth and Reproduction, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark
International Centre for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark
Section of Biostatistics, University of Copenhagen, Copenhagen, Denmark
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International Centre for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark
Section of Biostatistics, University of Copenhagen, Copenhagen, Denmark
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Louise Laub Asserhøj
Louise Laub Asserhøj
Department of Growth and Reproduction, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark
International Centre for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark
Department of Fertility, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark
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International Centre for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark
Department of Fertility, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark
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Trine Holm Johannsen
Trine Holm Johannsen
Department of Growth and Reproduction, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark
International Centre for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark
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International Centre for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark
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Peter Christiansen
Peter Christiansen
Department of Growth and Reproduction, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark
International Centre for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark
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International Centre for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark
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Rikke Beck Jensen
Rikke Beck Jensen
Department of Growth and Reproduction, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark
International Centre for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark
Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark
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International Centre for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark
Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark
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Line Hartvig Cleemann
Line Hartvig Cleemann
Department of Growth and Reproduction, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark
International Centre for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark
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International Centre for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark
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Casper P Hagen
Casper P Hagen
Department of Growth and Reproduction, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark
International Centre for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark
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International Centre for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark
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Lærke Priskorn
Lærke Priskorn
Department of Growth and Reproduction, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark
International Centre for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark
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International Centre for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark
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Niels Jørgensen
Niels Jørgensen
Department of Growth and Reproduction, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark
International Centre for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark
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International Centre for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark
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Katharina M Main
Katharina M Main
Department of Growth and Reproduction, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark
International Centre for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark
Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark
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International Centre for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark
Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark
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Anders Juul
Anders Juul
Department of Growth and Reproduction, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark
International Centre for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark
Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark
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International Centre for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark
Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark
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Lise Aksglaede
Lise Aksglaede
Department of Growth and Reproduction, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark
International Centre for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark
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International Centre for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark
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irrespective of the treatment status. These results confirm that patients with KS appear to have an unfavorable body composition and impaired bone status already during childhood and adolescence. Body composition It is well described that adult patients
