Liangming Li
Liangming Li
Center for Scientific Research and Institute of Exercise and Health, Guangzhou Sport University, Guangzhou, China
Key Laboratory of Sports Technique, Tactics and Physical Function of General Administration of Sport of China, Scientific Research Center, Guangzhou Sport University, Guangzhou, China
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Key Laboratory of Sports Technique, Tactics and Physical Function of General Administration of Sport of China, Scientific Research Center, Guangzhou Sport University, Guangzhou, China
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Yuan Wei
Yuan Wei
Center for Scientific Research and Institute of Exercise and Health, Guangzhou Sport University, Guangzhou, China
Key Laboratory of Sports Technique, Tactics and Physical Function of General Administration of Sport of China, Scientific Research Center, Guangzhou Sport University, Guangzhou, China
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Key Laboratory of Sports Technique, Tactics and Physical Function of General Administration of Sport of China, Scientific Research Center, Guangzhou Sport University, Guangzhou, China
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Chunlu Fang
Chunlu Fang
Center for Scientific Research and Institute of Exercise and Health, Guangzhou Sport University, Guangzhou, China
Key Laboratory of Sports Technique, Tactics and Physical Function of General Administration of Sport of China, Scientific Research Center, Guangzhou Sport University, Guangzhou, China
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Key Laboratory of Sports Technique, Tactics and Physical Function of General Administration of Sport of China, Scientific Research Center, Guangzhou Sport University, Guangzhou, China
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Shujing Liu
Shujing Liu
Center for Scientific Research and Institute of Exercise and Health, Guangzhou Sport University, Guangzhou, China
Key Laboratory of Sports Technique, Tactics and Physical Function of General Administration of Sport of China, Scientific Research Center, Guangzhou Sport University, Guangzhou, China
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Key Laboratory of Sports Technique, Tactics and Physical Function of General Administration of Sport of China, Scientific Research Center, Guangzhou Sport University, Guangzhou, China
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Fu Zhou
Fu Zhou
Key Laboratory of Sports Technique, Tactics and Physical Function of General Administration of Sport of China, Scientific Research Center, Guangzhou Sport University, Guangzhou, China
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Ge Zhao
Ge Zhao
Key Laboratory of Sports Technique, Tactics and Physical Function of General Administration of Sport of China, Scientific Research Center, Guangzhou Sport University, Guangzhou, China
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Yaping Li
Yaping Li
Key Laboratory of Sports Technique, Tactics and Physical Function of General Administration of Sport of China, Scientific Research Center, Guangzhou Sport University, Guangzhou, China
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Yuan Luo
Yuan Luo
Key Laboratory of Sports Technique, Tactics and Physical Function of General Administration of Sport of China, Scientific Research Center, Guangzhou Sport University, Guangzhou, China
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Ziyi Guo
Ziyi Guo
Key Laboratory of Sports Technique, Tactics and Physical Function of General Administration of Sport of China, Scientific Research Center, Guangzhou Sport University, Guangzhou, China
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Weiqun Lin
Weiqun Lin
Department of Clinical Nutrition, The First Affiliated Hospital of Guangdong Pharmaceutical University, Guangzhou, China
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Wenqi Yang
Wenqi Yang
Center for Scientific Research and Institute of Exercise and Health, Guangzhou Sport University, Guangzhou, China
Key Laboratory of Sports Technique, Tactics and Physical Function of General Administration of Sport of China, Scientific Research Center, Guangzhou Sport University, Guangzhou, China
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Key Laboratory of Sports Technique, Tactics and Physical Function of General Administration of Sport of China, Scientific Research Center, Guangzhou Sport University, Guangzhou, China
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tissue fibrosis ( 7 , 8 ). Adipocytes are surrounded by a network of extracellular matrix (ECM) mainly composed of collagens and fibronectin. Adipose fibrosis is defined as an excessive accumulation of ECM components ( 9 ). It has been demonstrated
Huiyuan Zhai
Huiyuan Zhai
Department of Pharmacy, Nanjing Integrated Traditional Chinese and Western Medicine Hospital, Affiliated with Nanjing University of Chinese Medicine, Nanjing, China
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Dongxu Wang
Dongxu Wang
Department of Geriatrics, Nanjing Integrated Traditional Chinese and Western Medicine Hospital, Affiliated with Nanjing University of Chinese Medicine, Nanjing, China
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Yong Wang
Yong Wang
Department of Pharmacy, Nanjing Integrated Traditional Chinese and Western Medicine Hospital, Affiliated with Nanjing University of Chinese Medicine, Nanjing, China
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Hongwei Gu
Hongwei Gu
Central Laboratory, Nanjing Integrated Traditional Chinese and Western Medicine Hospital, Affiliated with Nanjing University of Chinese Medicine, Nanjing, China
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Juan Jv
Juan Jv
Department of Cardiology, Nanjing Integrated Traditional Chinese and Western Medicine Hospital, Affiliated with Nanjing University of Chinese Medicine, Nanjing, China
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Liangliang Yuan
Liangliang Yuan
Department of Pharmacy, Nanjing Integrated Traditional Chinese and Western Medicine Hospital, Affiliated with Nanjing University of Chinese Medicine, Nanjing, China
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Chao Wang
Chao Wang
Department of Pharmacy, Nanjing Integrated Traditional Chinese and Western Medicine Hospital, Affiliated with Nanjing University of Chinese Medicine, Nanjing, China
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Leiyao Chen
Leiyao Chen
Department of Pharmacy, Nanjing Integrated Traditional Chinese and Western Medicine Hospital, Affiliated with Nanjing University of Chinese Medicine, Nanjing, China
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(adiponectin, IL-10) ( 4 ). Chronic inflammation in obese adipose tissues is characterized by a substantial infiltration of macrophages ( 5 ). In the context of prolonged positive energy homeostasis, adipose tissue undergoes expansion to accommodate increased
Hong-Fa Yan
Hong-Fa Yan
College of Life and Health Sciences, Northeastern University, Shenyang, China
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Zhao-Yu Liu
Zhao-Yu Liu
College of Life and Health Sciences, Northeastern University, Shenyang, China
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Zhi-Ang Guan
Zhi-Ang Guan
College of Life and Health Sciences, Northeastern University, Shenyang, China
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Chuang Guo
Chuang Guo
College of Life and Health Sciences, Northeastern University, Shenyang, China
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adipose tissues of patients and rodent models with diabetes mellitus (DM) ( 5 , 8 , 9 , 10 ), but less is understood about the mechanisms underlying these associations. In adipose tissue, intracellular mediators of iron homeostasis, including iron
Xianghe Chen
Xianghe Chen
College of Physical Education, Yangzhou University, Yangzhou, Jiangsu, China
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Xinyu Zeng
Xinyu Zeng
College of Physical Education, Yangzhou University, Yangzhou, Jiangsu, China
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Xiao Qiu
Xiao Qiu
College of Physical Education, Yangzhou University, Yangzhou, Jiangsu, China
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Chi Liu
Chi Liu
College of Physical Education, Yangzhou University, Yangzhou, Jiangsu, China
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Pengcheng Lu
Pengcheng Lu
College of Physical Education, Yangzhou University, Yangzhou, Jiangsu, China
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Ziming Shen
Ziming Shen
College of Physical Education, Yangzhou University, Yangzhou, Jiangsu, China
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Xiangxiang Zhou
Xiangxiang Zhou
College of Physical Education, Yangzhou University, Yangzhou, Jiangsu, China
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Kang Yang
Kang Yang
Department of Rehabilitation Medicine, Northern Jiangsu People's Hospital Affiliated to Yangzhou University, Yangzhou, Jiangsu, China
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Sirt1-mediated TGF-β1/Smad3 pathway in improvement of renal interstitial fibrosis associated with exercise were analyzed at multiple levels, such as renal tissue structure, degree of renal tissue fibrosis and gene expression using hematoxylin and eosin
Julia H Goedecke
Julia H Goedecke
Non-communicable Diseases Research Unit, South African Medical Research Council, Cape Town, South Africa
Division of Exercise Science and Sport Medicine, Department of Human Biology, University of Cape Town, 3 Floor Sports Science Institute of South Africa Cape Town, South Africa
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Division of Exercise Science and Sport Medicine, Department of Human Biology, University of Cape Town, 3 Floor Sports Science Institute of South Africa Cape Town, South Africa
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Mehreen Tootla
Mehreen Tootla
Division of Exercise Science and Sport Medicine, Department of Human Biology, University of Cape Town, 3 Floor Sports Science Institute of South Africa Cape Town, South Africa
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Dheshnie Keswell
Dheshnie Keswell
Division of Exercise Science and Sport Medicine, Department of Human Biology, University of Cape Town, 3 Floor Sports Science Institute of South Africa Cape Town, South Africa
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expansion, inflammation, and fibrosis . Molecular Metabolism 2013 2 227 – 242 . ( https://doi.org/10.1016/j.molmet.2013.05.006 ) 10.1016/j.molmet.2013.05.006 24049737 26 Virtue S Vidal-Puig A. Adipose tissue expandability, lipotoxicity and
David Koeckerling
David Koeckerling
Medical Sciences Division, University of Oxford, Oxford, UK
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Jeremy W Tomlinson
Jeremy W Tomlinson
Oxford Centre for Diabetes, Endocrinology & Metabolism, University of Oxford, Oxford, UK
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Jeremy F Cobbold
Jeremy F Cobbold
Oxford Liver Unit, NIHR Oxford Biomedical Research Centre, Oxford University Hospitals NHS Foundation Trust, John Radcliffe Hospital, Oxford, UK
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lipid export or degradation is exceeded by lipid import or synthesis. Main sources of hepatic lipid aggregation are a flux of free fatty acids (FFA) from peripheral adipose tissue (59%), followed by hepatic de novo lipogenesis (26%) and dietary intake
Michaela Keuper
Michaela Keuper
Department of Molecular Biosciences, The Wenner-Gren Institute, Stockholm University, Stockholm, Sweden
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N Gurley CM Zhu B Peterson CA Kern PA . Adipose tissue macrophages in insulin-resistant subjects are associated with collagen VI and fibrosis and demonstrate alternative activation . American Journal of Physiology: Endocrinology and
Antonia Ertelt
Antonia Ertelt
Equine Clinic, Free University of Berlin, Berlin, Germany
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Ann-Kristin Barton
Ann-Kristin Barton
Equine Clinic, Free University of Berlin, Berlin, Germany
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Robert R Schmitz
Robert R Schmitz
Equine Clinic, Free University of Berlin, Berlin, Germany
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Heidrun Gehlen
Heidrun Gehlen
Equine Clinic, Free University of Berlin, Berlin, Germany
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this paper, we aimed to review similarities and differences between EMS and HMS, as this may allow transfer of knowledge between both species. Anatomy and physiology of adipose tissue Adipose or fat tissue, a special form of reticular connective tissue
Lars Peter Sørensen
Lars Peter Sørensen
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Tina Parkner
Tina Parkner
Department of Endocrinology and Internal Medicine, Department of Clinical Biochemistry, Department of Biostatistics, Department of Clinical Biochemistry, Aarhus University Hospital, Nørrebrogade 44, 8000 Aarhus C, Denmark
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Esben Søndergaard
Esben Søndergaard
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Bo Martin Bibby
Bo Martin Bibby
Department of Endocrinology and Internal Medicine, Department of Clinical Biochemistry, Department of Biostatistics, Department of Clinical Biochemistry, Aarhus University Hospital, Nørrebrogade 44, 8000 Aarhus C, Denmark
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Holger Jon Møller
Holger Jon Møller
Department of Endocrinology and Internal Medicine, Department of Clinical Biochemistry, Department of Biostatistics, Department of Clinical Biochemistry, Aarhus University Hospital, Nørrebrogade 44, 8000 Aarhus C, Denmark
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Søren Nielsen
Søren Nielsen
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-associated insulin resistance remain unclear, but it is well established that not only the amount, but also the distribution of excess body fat is important, and that white adipose tissue (WAT) inflammation and insulin resistance are inter-related (2) . Studies have
Tatsuya Kondo
Tatsuya Kondo
Department of Diabetes, Metabolism and Endocrinology, Kumamoto University Hospital, Chuo-Ward, Kumamoto, Japan
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Nobukazu Miyakawa
Nobukazu Miyakawa
Department of Metabolic Medicine, Faculty of Life Sciences, Kumamoto University, Chuo-Ward, Kumamoto, Japan
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Sayaka Kitano
Sayaka Kitano
Department of Diabetes, Metabolism and Endocrinology, Kumamoto University Hospital, Chuo-Ward, Kumamoto, Japan
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Takuro Watanabe
Takuro Watanabe
Department of Metabolic Medicine, Faculty of Life Sciences, Kumamoto University, Chuo-Ward, Kumamoto, Japan
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Rieko Goto
Rieko Goto
Department of Metabolic Medicine, Faculty of Life Sciences, Kumamoto University, Chuo-Ward, Kumamoto, Japan
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Mary Ann Suico
Mary Ann Suico
Department of Molecular Medicine, Faculty of Life Sciences, Kumamoto University, Chuo-Ward, Kumamoto, Japan
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Miki Sato
Miki Sato
Department of Metabolic Medicine, Faculty of Life Sciences, Kumamoto University, Chuo-Ward, Kumamoto, Japan
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Yuki Takaki
Yuki Takaki
Department of Metabolic Medicine, Faculty of Life Sciences, Kumamoto University, Chuo-Ward, Kumamoto, Japan
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Masaji Sakaguchi
Masaji Sakaguchi
Department of Metabolic Medicine, Faculty of Life Sciences, Kumamoto University, Chuo-Ward, Kumamoto, Japan
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Motoyuki Igata
Motoyuki Igata
Department of Diabetes, Metabolism and Endocrinology, Kumamoto University Hospital, Chuo-Ward, Kumamoto, Japan
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Junji Kawashima
Junji Kawashima
Department of Metabolic Medicine, Faculty of Life Sciences, Kumamoto University, Chuo-Ward, Kumamoto, Japan
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Hiroyuki Motoshima
Hiroyuki Motoshima
Department of Metabolic Medicine, Faculty of Life Sciences, Kumamoto University, Chuo-Ward, Kumamoto, Japan
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Takeshi Matsumura
Takeshi Matsumura
Department of Metabolic Medicine, Faculty of Life Sciences, Kumamoto University, Chuo-Ward, Kumamoto, Japan
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Hirofumi Kai
Hirofumi Kai
Department of Molecular Medicine, Faculty of Life Sciences, Kumamoto University, Chuo-Ward, Kumamoto, Japan
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Eiichi Araki
Eiichi Araki
Department of Metabolic Medicine, Faculty of Life Sciences, Kumamoto University, Chuo-Ward, Kumamoto, Japan
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to fibrosis and the expression/activation of the HSF1/HSP72 biochemical pathway is observed in both the liver and adipose tissues of patients with NAFLD ( 40 ). This suppression of the HSF1–HSP72 axis is strongly correlated with the degree of
