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Paul-Martin Holterhus Department of Pediatrics I, Pediatric Endocrinology and Diabetology, University Hospital of Schleswig-Holstein, UKSH, Campus Kiel and Christian Albrechts University, CAU, Kiel, Germany

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Alexandra Kulle Department of Pediatrics I, Pediatric Endocrinology and Diabetology, University Hospital of Schleswig-Holstein, UKSH, Campus Kiel and Christian Albrechts University, CAU, Kiel, Germany

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Anne-Marie Till Department of Pediatrics, Pediatric Hematology and Oncology, University Hospital of Schleswig-Holstein, UKSH, Campus Lübeck, Germany

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Caroline Stille Department of Pediatrics, Pediatric Hematology and Oncology, University Hospital of Schleswig-Holstein, UKSH, Campus Lübeck, Germany

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Tabea Lamprecht Department of Pediatrics I, Pediatric Endocrinology and Diabetology, University Hospital of Schleswig-Holstein, UKSH, Campus Kiel and Christian Albrechts University, CAU, Kiel, Germany

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Simon Vieth Department of Pediatrics I, Pediatric Hematology and Oncology, University Hospital of Schleswig-Holstein, UKSH, Campus Kiel and Christian-Albrechts-University, CAU, Kiel, Germany

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Melchior Lauten Department of Pediatrics, Pediatric Hematology and Oncology, University Hospital of Schleswig-Holstein, UKSH, Campus Lübeck, Germany

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Introduction High-dose glucocorticoids are indispensable in the treatment of childhood acute lymphoblastic leukemia (ALL) ( 1 ). Two different highly potent synthetic glucocorticoids are used in the current standard protocols, namely

Article Type:
Research Article
Collections:
Adrenal
DOI:
https://doi.org/10.1530/EC-23-0002
Volume/Issue:
Volume 12: Issue 10
Open access
Sandrine Visentin Department of Pediatric Hematology and Oncology, AP-HM, Timone Enfants Hospital, Marseille, France
Aix Marseille University, INSERM, INRA, C2VN, Marseille, France

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Gérard Michel Department of Pediatric Hematology and Oncology, AP-HM, Timone Enfants Hospital, Marseille, France
Research Unit EA 3279 and Department of Public Health, Aix-Marseille University, Marseille, France

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Claire Oudin Department of Pediatric Hematology and Oncology, AP-HM, Timone Enfants Hospital, Marseille, France
Research Unit EA 3279 and Department of Public Health, Aix-Marseille University, Marseille, France

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Béatrice Cousin STROMALab, Université de Toulouse, CNRS ERL5311, EFS, INP-ENVT, INSERM U1031, UPS, Toulouse, France

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Bénédicte Gaborit Aix Marseille University, INSERM, INRA, C2VN, Marseille, France

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Inès Abdesselam Aix Marseille University, INSERM, INRA, C2VN, Marseille, France

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Marie Maraninchi Aix Marseille University, INSERM, INRA, C2VN, Marseille, France

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Marion Nowicki Aix Marseille University, INSERM, INRA, C2VN, Marseille, France

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René Valéro Aix Marseille University, INSERM, INRA, C2VN, Marseille, France
Nutrition, Metabolic Diseases and Endocrinology Department, AP-HM, La Conception Hospital, Marseille, France

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Maxime Guye AP-HM, Timone, CEMEREM, Marseille, France

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Monique Bernard AP-HM, Timone, CEMEREM, Marseille, France
Aix-Marseille University, CNRS, CRMBM, Marseille, France

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Pascal Auquier Research Unit EA 3279 and Department of Public Health, Aix-Marseille University, Marseille, France

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Hervé Chambost Department of Pediatric Hematology and Oncology, AP-HM, Timone Enfants Hospital, Marseille, France

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Marie-Christine Alessi Aix Marseille University, INSERM, INRA, C2VN, Marseille, France

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Sophie Béliard Aix Marseille University, INSERM, INRA, C2VN, Marseille, France
Nutrition, Metabolic Diseases and Endocrinology Department, AP-HM, La Conception Hospital, Marseille, France

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Introduction Advances in the treatment strategies and supportive care for childhood acute leukemia (AL) have resulted in marked improvements in survival, which now exceeds 80% for lymphoblastic and 60% for myeloid AL ( 1 ). However, long

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-18-0497
Volume/Issue:
Volume 8: Issue 4
Open access
Sidsel Mathiesen Department of Pediatrics and Adolescent Medicine, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark

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Kaspar Sørensen Department of Pediatrics and Adolescent Medicine, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark

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Marianne Ifversen Department of Pediatrics and Adolescent Medicine, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark

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Casper P Hagen Department of Growth and Reproduction, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark

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Jørgen Holm Petersen Department of Growth and Reproduction, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
Section of Biostatistics, Department of Public Health, University of Copenhagen, Copenhagen, Denmark

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Anders Juul Department of Growth and Reproduction, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark

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Klaus Müller Department of Pediatrics and Adolescent Medicine, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark

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.1–26.3) 20.1 (7.7–27.3) 15.8 (8.6–25.1) Diagnosis (malignant vs non-malignant)  Malignancies, n (%) 29 (74) 22 (59) 19 (73) 10 (77)   Acute lymphoblastic leukemia 12 13 9 3   Acute myeloid leukemia 6 2

Article Type:
Research Article
Collections:
Paediatric Endocrinology Collection
DOI:
https://doi.org/10.1530/EC-21-0154
Volume/Issue:
Volume 10: Issue 10
Open access
Keina Nishio Department of Obstetrics and Gynecology, Osaka Medical College, 2-7 Daigaku-machi, Takatsuki-city, Osaka 569-8686, Japan

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Akiko Tanabe Department of Obstetrics and Gynecology, Osaka Medical College, 2-7 Daigaku-machi, Takatsuki-city, Osaka 569-8686, Japan

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Risa Maruoka Department of Obstetrics and Gynecology, Osaka Medical College, 2-7 Daigaku-machi, Takatsuki-city, Osaka 569-8686, Japan

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Kiyoko Nakamura Department of Obstetrics and Gynecology, Osaka Medical College, 2-7 Daigaku-machi, Takatsuki-city, Osaka 569-8686, Japan

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Masaaki Takai Department of Obstetrics and Gynecology, Osaka Medical College, 2-7 Daigaku-machi, Takatsuki-city, Osaka 569-8686, Japan

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Tatsuharu Sekijima Department of Obstetrics and Gynecology, Osaka Medical College, 2-7 Daigaku-machi, Takatsuki-city, Osaka 569-8686, Japan

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Satoshi Tunetoh Department of Obstetrics and Gynecology, Osaka Medical College, 2-7 Daigaku-machi, Takatsuki-city, Osaka 569-8686, Japan

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Yoshito Terai Department of Obstetrics and Gynecology, Osaka Medical College, 2-7 Daigaku-machi, Takatsuki-city, Osaka 569-8686, Japan

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Masahide Ohmichi Department of Obstetrics and Gynecology, Osaka Medical College, 2-7 Daigaku-machi, Takatsuki-city, Osaka 569-8686, Japan

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. ( doi:10.2146/ajhp050045.p1 ). 9 Atkinson SA Fraher L Gundberg CM Andrew M Pai M Barr RD . Mineral homeostasis and bone mass in children treated for acute lymphoblastic leukemia . Journal of

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-12-0043
Volume/Issue:
Volume 2: Issue 1
Open access
Nikolaos Kyriakakis Department of Endocrinology, Leeds Centre for Diabetes & Endocrinology, Leeds Teaching Hospitals NHS Trust, Leeds, UK
Leeds Institute for Cardiovascular and Metabolic Medicine (LICAMM), University of Leeds, Leeds, UK

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Marilena Giannoudi Department of Endocrinology, Leeds Centre for Diabetes & Endocrinology, Leeds Teaching Hospitals NHS Trust, Leeds, UK

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Satish S Kumar Department of Endocrinology, Leeds Centre for Diabetes & Endocrinology, Leeds Teaching Hospitals NHS Trust, Leeds, UK

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Khyatisha Seejore Department of Endocrinology, Leeds Centre for Diabetes & Endocrinology, Leeds Teaching Hospitals NHS Trust, Leeds, UK
Leeds Institute for Cardiovascular and Metabolic Medicine (LICAMM), University of Leeds, Leeds, UK

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Georgios K Dimitriadis Department of Endocrinology, King’s College Hospital NHS Foundation Trust, Denmark Hill, London, UK

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Harpal Randeva Warwickshire Institute for the Study of Diabetes, Endocrinology and Metabolism (WISDEM), University Hospitals Coventry and Warwickshire NHS Trust, Coventry, UK

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Adam Glaser Pediatric Oncology, Leeds General Infirmary, Leeds Teaching Hospitals NHS Trust, Leeds, UK
Leeds Institute of Medical Research, University of Leeds, UK

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Michelle Kwok-Williams Clinical Oncology, Leeds Cancer Centre, Leeds Teaching Hospitals NHS Trust, Leeds, UK

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Georgina Gerrard Clinical Oncology, Leeds Cancer Centre, Leeds Teaching Hospitals NHS Trust, Leeds, UK

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Carmel Loughrey Clinical Oncology, Leeds Cancer Centre, Leeds Teaching Hospitals NHS Trust, Leeds, UK

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Ahmed Al-Qaissi Department of Endocrinology, Leeds Centre for Diabetes & Endocrinology, Leeds Teaching Hospitals NHS Trust, Leeds, UK

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Ramzi Ajjan Leeds Institute for Cardiovascular and Metabolic Medicine (LICAMM), University of Leeds, Leeds, UK

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Julie Lynch Department of Endocrinology, Leeds Centre for Diabetes & Endocrinology, Leeds Teaching Hospitals NHS Trust, Leeds, UK

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Robert D Murray Department of Endocrinology, Leeds Centre for Diabetes & Endocrinology, Leeds Teaching Hospitals NHS Trust, Leeds, UK
Leeds Institute for Cardiovascular and Metabolic Medicine (LICAMM), University of Leeds, Leeds, UK

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survivors of childhood acute lymphoblastic leukemia: role of cranial irradiation . Medical and Pediatric Oncology 2000 35 91 – 95 . (https://doi.org/10.1002/1096-911x(200008)35:2<91::aid-mpo1>3.0.co;2-g) 13 Oeffinger KC Mertens AC Sklar CA Yasui Y

Article Type:
Research Article
Collections:
Hormones and Cancer
DOI:
https://doi.org/10.1530/EC-22-0491
Volume/Issue:
Volume 12: Issue 8
Open access
Legh Wilkinson Department of Biochemistry, Stellenbosch University, Stellenbosch, South Africa

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Nicolette J D Verhoog Department of Biochemistry, Stellenbosch University, Stellenbosch, South Africa

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Ann Louw Department of Biochemistry, Stellenbosch University, Stellenbosch, South Africa

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-3p in human T-cell acute lymphoblastic leukemia (T-ALL) by targeting glucocorticoid receptor-α and cAMP/PKA pathways . Leukemia 2012 26 769 – 777 . ( https://doi.org/10.1038/leu.2011.273 ) 85 Jones CL Gearheart CM Fosmire S Delgado-Martin C

Article Type:
Review Article
DOI:
https://doi.org/10.1530/EC-18-0421
Volume/Issue:
Volume 7: Issue 12
Open access
Ichelle Maa van Roessel Department of Pediatric Endocrinology, Wilhelmina Children's Hospital, University Medical Center Utrecht, AB Utrecht, The Netherlands
Princess Máxima Center for Pediatric Oncology, AB Utrecht, The Netherlands

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Boudewijn Bakker Department of Pediatric Endocrinology, Wilhelmina Children's Hospital, University Medical Center Utrecht, AB Utrecht, The Netherlands
Princess Máxima Center for Pediatric Oncology, AB Utrecht, The Netherlands

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Hanneke M van Santen Department of Pediatric Endocrinology, Wilhelmina Children's Hospital, University Medical Center Utrecht, AB Utrecht, The Netherlands
Princess Máxima Center for Pediatric Oncology, AB Utrecht, The Netherlands

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Wassim Chemaitilly Division of Pediatric Endocrinology, UPMC Children’s Hospitalof Pittsburgh, Pittsburgh, Pennsylvania, USA

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survivors of acute lymphoblastic leukemia with a history of cranial irradiation ( 12 ), those treated with total body irradiation prior to hematopoietic stem cell transplantation and survivors of non-brain solid tumors of the head whose treatment included

Article Type:
Review Article
Collections:
Pituitary and Hypothalamus
DOI:
https://doi.org/10.1530/EC-22-0382
Volume/Issue:
Volume 12: Issue 1
Open access
Konstantin Yakimchuk Department of Biosciences and Nutrition Karolinska Institutet, Neo, Huddinge, Sweden

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Chandrashekar Bangalore Revanna Department of Biosciences and Nutrition Karolinska Institutet, Neo, Huddinge, Sweden

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Dan Huang Department of Biosciences and Nutrition Karolinska Institutet, Neo, Huddinge, Sweden

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Jose Inzunza Department of Biosciences and Nutrition Karolinska Institutet, Neo, Huddinge, Sweden

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Sam Okret Department of Biosciences and Nutrition Karolinska Institutet, Neo, Huddinge, Sweden

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( 40 ). As to the effects of genistein on malignant lymphoid cell types, earlier in vitro studies have demonstrated suppression of proliferation and induction of apoptosis by genistein in human acute T lymphoblastic leukemia Jurkat and B lymphoma

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-18-0459
Volume/Issue:
Volume 7: Issue 12
Open access
Elham Barazeghi Department of Surgical Sciences, Uppsala University, Uppsala University Hospital, Rudbeck Laboratory, Uppsala, Sweden

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Per Hellman Department of Surgical Sciences, Uppsala University, Uppsala University Hospital, Rudbeck Laboratory, Uppsala, Sweden

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Gunnar Westin Department of Surgical Sciences, Uppsala University, Uppsala University Hospital, Rudbeck Laboratory, Uppsala, Sweden

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Peter Stålberg Department of Surgical Sciences, Uppsala University, Uppsala University Hospital, Rudbeck Laboratory, Uppsala, Sweden

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mediates cell–cell aggregation through interaction with other subfamily members. PTPRM has been shown to be frequently hypermethylated at the promoter in acute lymphoblastic leukemia ( 10 ), and downregulation of PTPRM due to aberrant DNA promoter

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-19-0279
Volume/Issue:
Volume 8: Issue 8
Open access
Wafaa M Rashed Research Department, Children’s Cancer Hospital Egypt (CCHE-57357), Cairo, Egypt
Armed Forces College of Medicine, Cairo, Egypt

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Anas Saad Faculty of Medicine, Damascus University, Damascus, Syria

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Muneer Al-Husseini Faculty of Medicine, Ain Shams University, Cairo, Egypt

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Ahmed Mahmoud Galal Armed Forces College of Medicine, Cairo, Egypt

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Assem Mohamed Ismael Armed Forces College of Medicine, Cairo, Egypt

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Ahmed M Al-Tayep Armed Forces College of Medicine, Cairo, Egypt

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Ayman El Shafie Armed Forces College of Medicine, Cairo, Egypt

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Mahmoud Ahmed Ali Armed Forces College of Medicine, Cairo, Egypt

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Ahmad Samir Alfaar Charité – Universitätsmedizin Berlin, Campus Virchow Klinikum, Ophthalmology Department, Berlin, Germany

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.1159/000225970 19546604 33 Rashed WM Zekri W Awad M Taha H Abdalla B Alfaar AS . Nonfunctioning adrenocortical carcinoma in pediatric acute lymphoblastic leukemia: a case report of a Rare Multiple Primaries Combination . Journal of Pediatric Hematology/Oncology 2017

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-18-0304
Volume/Issue:
Volume 7: Issue 10
Open access