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Benjamin D Maylor Institute for Sport and Physical Activity Research, School of Sport Science and Physical Activity, University of Bedfordshire, Bedford, UK
Leicester Diabetes Centre, University of Leicester, Leicester General Hospital, Leicester, UK

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Julia K Zakrzewski-Fruer Institute for Sport and Physical Activity Research, School of Sport Science and Physical Activity, University of Bedfordshire, Bedford, UK

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Charlie J Orton Institute for Sport and Physical Activity Research, School of Sport Science and Physical Activity, University of Bedfordshire, Bedford, UK

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Daniel P Bailey Institute for Sport and Physical Activity Research, School of Sport Science and Physical Activity, University of Bedfordshire, Bedford, UK
Centre for Physical Activity in Health and Disease, Brunel University London, Uxbridge, UK
Division of Sport, Health and Exercise Sciences, Department of Life Sciences, Brunel University London, Uxbridge, UK

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of accumulating physical activity in short regular bouts to break up sitting ( 6 ), the effects of this pattern of physical activity on appetite are not well understood. This is important as a reduction in energy expenditure due to a single day of

Article Type:
Research Article
Collections:
Metabolic Syndrome and Diabetes
DOI:
https://doi.org/10.1530/EC-22-0259
Volume/Issue:
Volume 12: Issue 2
Open access
Ingeborg Brønstad Department of Clinical Science, Department of Medicine, Division of Medicine, University of Bergen, 5021 Bergen, Norway

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Lars Breivik Department of Clinical Science, Department of Medicine, Division of Medicine, University of Bergen, 5021 Bergen, Norway

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Paal Methlie Department of Clinical Science, Department of Medicine, Division of Medicine, University of Bergen, 5021 Bergen, Norway
Department of Clinical Science, Department of Medicine, Division of Medicine, University of Bergen, 5021 Bergen, Norway

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Anette S B Wolff Department of Clinical Science, Department of Medicine, Division of Medicine, University of Bergen, 5021 Bergen, Norway

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Eirik Bratland Department of Clinical Science, Department of Medicine, Division of Medicine, University of Bergen, 5021 Bergen, Norway

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Ingrid Nermoen Department of Clinical Science, Department of Medicine, Division of Medicine, University of Bergen, 5021 Bergen, Norway

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Kristian Løvås Department of Clinical Science, Department of Medicine, Division of Medicine, University of Bergen, 5021 Bergen, Norway
Department of Clinical Science, Department of Medicine, Division of Medicine, University of Bergen, 5021 Bergen, Norway

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Eystein S Husebye Department of Clinical Science, Department of Medicine, Division of Medicine, University of Bergen, 5021 Bergen, Norway
Department of Clinical Science, Department of Medicine, Division of Medicine, University of Bergen, 5021 Bergen, Norway

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almost complete loss of enzyme activity, leading to lack of cortisol and aldosterone, whereas the SV displays various degrees of reduced enzyme activity resulting in cortisol insufficiency (1, 2) . The non-classical (NC) CAH is milder and characterised

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-14-0032
Volume/Issue:
Volume 3: Issue 2
Open access
Fernando Aprile-Garcia Instituto de Investigación en Biomedicina de Buenos Aires – CONICET, Departamento de Fisiología, Partner Institute of the Max Planck Society, Buenos Aires, Argentina
Instituto de Investigación en Biomedicina de Buenos Aires – CONICET, Departamento de Fisiología, Partner Institute of the Max Planck Society, Buenos Aires, Argentina

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María Antunica-Noguerol Instituto de Investigación en Biomedicina de Buenos Aires – CONICET, Departamento de Fisiología, Partner Institute of the Max Planck Society, Buenos Aires, Argentina
Instituto de Investigación en Biomedicina de Buenos Aires – CONICET, Departamento de Fisiología, Partner Institute of the Max Planck Society, Buenos Aires, Argentina

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Maia Ludmila Budziñski Instituto de Investigación en Biomedicina de Buenos Aires – CONICET, Departamento de Fisiología, Partner Institute of the Max Planck Society, Buenos Aires, Argentina

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Ana C Liberman Instituto de Investigación en Biomedicina de Buenos Aires – CONICET, Departamento de Fisiología, Partner Institute of the Max Planck Society, Buenos Aires, Argentina

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Eduardo Arzt Instituto de Investigación en Biomedicina de Buenos Aires – CONICET, Departamento de Fisiología, Partner Institute of the Max Planck Society, Buenos Aires, Argentina
Instituto de Investigación en Biomedicina de Buenos Aires – CONICET, Departamento de Fisiología, Partner Institute of the Max Planck Society, Buenos Aires, Argentina

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their biological activity: progestins, androgens, estrogens, and corticoids. In turn, corticoids can be divided in mineralocorticoids, which regulate ion transport, and GCs, which have a wide variety of activities, including resistance to stress and

Article Type:
Review Article
DOI:
https://doi.org/10.1530/EC-13-0079
Volume/Issue:
Volume 3: Issue 1
Open access
Salem A Beshyah Department of Medicine, Dubai Medical College, Dubai, United Arab Emirates
Diabetes and Endocrine Clinic, Mediclinic Airport Road Hospital, Abu Dhabi, United Arab Emirates

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Khawla F Ali Department of Medicine, Royal College of Surgeons in Ireland Medical University of Bahrain, Adliya, Bahrain

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Hussein F Saadi Department of Endocrinology, Medical Subspecialties Institute, Cleveland Clinic Abu Dhabi, Abu Dhabi, United Arab Emirates

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morning dose to latest possible time before Suhor and take the evening dose as usual with the first evening meal, Change all my patients on hydrocortisone and cortisone acetate to prednisolone/prednisone, I warn my patients to break the fast and take

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-20-0314
Volume/Issue:
Volume 9: Issue 8
Open access
Hamidreza Mani Diabetes Research Centre, Leicester Diabetes Centre, University of Leicester, Leicester General Hospital, Leicester, UK
Department of Diabetes and Endocrinology, Leicester Royal Infirmary, University Hospitals of Leicester NHS Trust, Leicester, UK

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Yogini Chudasama Diabetes Research Centre, Leicester Diabetes Centre, University of Leicester, Leicester General Hospital, Leicester, UK

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Michelle Hadjiconstantinou Diabetes Research Centre, Leicester Diabetes Centre, University of Leicester, Leicester General Hospital, Leicester, UK

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Danielle H Bodicoat Diabetes Research Centre, Leicester Diabetes Centre, University of Leicester, Leicester General Hospital, Leicester, UK

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Charlotte Edwardson Diabetes Research Centre, Leicester Diabetes Centre, University of Leicester, Leicester General Hospital, Leicester, UK
The Leicester Biomedical Research Centre, Leicester and Loughborough, UK

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Miles J Levy Department of Diabetes and Endocrinology, Leicester Royal Infirmary, University Hospitals of Leicester NHS Trust, Leicester, UK

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Laura J Gray Department of Health Sciences, University of Leicester, Leicester, UK

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Janette Barnett Department of Diabetes and Endocrinology, Leicester Royal Infirmary, University Hospitals of Leicester NHS Trust, Leicester, UK

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Heather Daly Leicester Medical Group, Thurmaston Health Centre, Leicester, UK

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Trevor A Howlett Department of Diabetes and Endocrinology, Leicester Royal Infirmary, University Hospitals of Leicester NHS Trust, Leicester, UK

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Kamlesh Khunti Diabetes Research Centre, Leicester Diabetes Centre, University of Leicester, Leicester General Hospital, Leicester, UK

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Melanie J Davies Diabetes Research Centre, Leicester Diabetes Centre, University of Leicester, Leicester General Hospital, Leicester, UK

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://www.desmond-project.org.uk ), might assist in lifestyle change (for example, increase physical activity) for women with PCOS by improving their understanding of their condition. Subjects and methods We conducted a single-centre, parallel randomised controlled trial (Ethical

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-17-0274
Volume/Issue:
Volume 7: Issue 1
Open access
Sheila Leone Department of Pharmacy, G. d’Annunzio University, Chieti, Italy

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Lucia Recinella Department of Pharmacy, G. d’Annunzio University, Chieti, Italy

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Annalisa Chiavaroli Department of Pharmacy, G. d’Annunzio University, Chieti, Italy

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Claudio Ferrante Department of Pharmacy, G. d’Annunzio University, Chieti, Italy

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Giustino Orlando Department of Pharmacy, G. d’Annunzio University, Chieti, Italy

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Michele Vacca Department of Pharmacy, G. d’Annunzio University, Chieti, Italy

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Roberto Salvatori Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA

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Luigi Brunetti Department of Pharmacy, G. d’Annunzio University, Chieti, Italy

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analysis Locomotor activity recordings show that 2-, 5- and 12-month-old −/− mice display increased travelled distance and number of Z-beam breaks compared to their age-matched +/− controls ( Fig. 6A and B ) ( F 2/9  = 4.26, P  = 0.0011; F 2

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-18-0165
Volume/Issue:
Volume 7: Issue 8
Open access
S U Jayasinghe
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S J Torres
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C A Nowson
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A J Tilbrook Centre for Physical Activity and Nutrition Research, Livestock and Farming Systems, School of Exercise and Nutrition Sciences, Deakin University, Burwood, Melbourne, Victoria 3125, Australia

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A I Turner
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amylase by the salivary glands (8, 9, 10, 11) . Simple sampling procedures of saliva make salivary alpha amylase a useful non-invasive measure of the SAM system activity (12) . Further advantages of salivary alpha amylase include its concentration being

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-14-0042
Volume/Issue:
Volume 3: Issue 3
Open access
Wei Li Department of Nuclear Medicine, Tianjin Medical University General Hospital, Tianjin, People’s Republic of China

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Qing Huang Collage of Tourism and Service Management, Nankai University, Tianjin, People’s Republic of China

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Danyang Sun Department of Nuclear Medicine, Tianjin Medical University General Hospital, Tianjin, People’s Republic of China

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Guizhi Zhang Department of Nuclear Medicine, Tianjin Medical University General Hospital, Tianjin, People’s Republic of China

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Jian Tan Department of Nuclear Medicine, Tianjin Medical University General Hospital, Tianjin, People’s Republic of China

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recombination and repair protein RAD52 ( 3 ). RDM1 can bind to RNA as well as single- and double-stranded DNA and is involved with DNA double-strand break (DSB) repair and recombination events. When the repair of DNA damage occurs, many genes are involved in

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-17-0209
Volume/Issue:
Volume 6: Issue 8
Open access
Kirsty G Pringle School of Biomedical Sciences and Pharmacy, University of Newcastle, Callaghan, New South Wales, Australia

Hunter Medical Research Institute, New Lambton, Newcastle, New South Wales, Australia

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Sarah J Delforce School of Biomedical Sciences and Pharmacy, University of Newcastle, Callaghan, New South Wales, Australia

Hunter Medical Research Institute, New Lambton, Newcastle, New South Wales, Australia

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Yu Wang School of Biomedical Sciences and Pharmacy, University of Newcastle, Callaghan, New South Wales, Australia

Hunter Medical Research Institute, New Lambton, Newcastle, New South Wales, Australia

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Katie A Ashton School of Biomedical Sciences and Pharmacy, University of Newcastle, Callaghan, New South Wales, Australia

Hunter Medical Research Institute, New Lambton, Newcastle, New South Wales, Australia

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Anthony Proietto Hunter Centre for Gynaecological Cancer, John Hunter Hospital, Newcastle, New South Wales, Australia

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Geoffrey Otton Hunter Centre for Gynaecological Cancer, John Hunter Hospital, Newcastle, New South Wales, Australia

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C Caroline Blackwell School of Biomedical Sciences and Pharmacy, University of Newcastle, Callaghan, New South Wales, Australia

Hunter Medical Research Institute, New Lambton, Newcastle, New South Wales, Australia

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Rodney J Scott School of Biomedical Sciences and Pharmacy, University of Newcastle, Callaghan, New South Wales, Australia

Hunter Medical Research Institute, New Lambton, Newcastle, New South Wales, Australia
Division of Molecular Medicine, Pathology North, Newcastle, New South Wales, Australia

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Eugenie R Lumbers School of Biomedical Sciences and Pharmacy, University of Newcastle, Callaghan, New South Wales, Australia

Hunter Medical Research Institute, New Lambton, Newcastle, New South Wales, Australia

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structures like serine proteinase inhibitors (serpins) but have no inhibitory activity. Other members of the serpin family that have no inhibitory activity include maspin (SERPINB5, a putative anti-tumour agent), which blocks angiogenesis ( 28 ). Celerier

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-15-0112
Volume/Issue:
Volume 5: Issue 3
Open access
Michael Ulm University of Tennessee Health Science Center, Memphis, Tennessee, USA
West Cancer Center, Memphis, Tennessee, USA

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Arvind V Ramesh White Station High School, Memphis, Tennessee, USA

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Keely M McNamara Tohoku University, Miyagi, Japan

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Suriyan Ponnusamy University of Tennessee Health Science Center, Memphis, Tennessee, USA

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Hironobu Sasano Tohoku University, Miyagi, Japan

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Ramesh Narayanan University of Tennessee Health Science Center, Memphis, Tennessee, USA
West Cancer Center, Memphis, Tennessee, USA

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splice variants (AR-SVs). CRPCs that have relapsed from existing treatments express AR-SVs. As AR-SVs lack LBD, they are constitutively active and fail to respond to LBD-targeted treatments. 6. Coregulators. AR activity depends on the expression of

Article Type:
Review Article
DOI:
https://doi.org/10.1530/EC-18-0425
Volume/Issue:
Volume 8: Issue 2
Open access