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Annette Mouritsen Department of Growth and Reproduction, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
International Center for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, University of Copenhagen, Copenhagen, Denmark

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Alexander Siegfried Busch Department of Growth and Reproduction, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
International Center for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, University of Copenhagen, Copenhagen, Denmark

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Lise Aksglaede Department of Growth and Reproduction, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
International Center for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, University of Copenhagen, Copenhagen, Denmark

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Ewa Rajpert-De Meyts Department of Growth and Reproduction, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
International Center for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, University of Copenhagen, Copenhagen, Denmark

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Anders Juul Department of Growth and Reproduction, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
International Center for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, University of Copenhagen, Copenhagen, Denmark

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urine depends on sulfation and glucuronidation of steroids to water-soluble conjugates. One of the several essential glucuronidases is uridine diphosphate glucuronyltransferase 2B17, encoded by the UGT2B17 gene, and several studies observed a lower

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-18-0080
Volume/Issue:
Volume 7: Issue 3
Open access
Nandini Shankara Narayana Andrology Department, Concord Hospital and, ANZAC Research Institute, University of Sydney, Sydney, Australia

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Lam P Ly Andrology Department, Concord Hospital and, ANZAC Research Institute, University of Sydney, Sydney, Australia

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Veena Jayadev Andrology Department, Concord Hospital and, ANZAC Research Institute, University of Sydney, Sydney, Australia

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Carolyn Fennell Andrology Department, Concord Hospital and, ANZAC Research Institute, University of Sydney, Sydney, Australia

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Sasha Savkovic Andrology Department, Concord Hospital and, ANZAC Research Institute, University of Sydney, Sydney, Australia

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Ann J Conway Andrology Department, Concord Hospital and, ANZAC Research Institute, University of Sydney, Sydney, Australia

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David J Handelsman Andrology Department, Concord Hospital and, ANZAC Research Institute, University of Sydney, Sydney, Australia

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diphospho-glucuronosyl transferase 2B17 (UGT2B17) polymorphism in testosterone glucuronidation rendering the steroid more hydrophilic for renal excretion ( 33 ). The UGT2B17 polymorphism primarily influences testosterone glucuronide excretion ( 34 ) but not

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-21-0109
Volume/Issue:
Volume 10: Issue 7
Open access
Emmely M de Vries Endocrine Laboratory, Department of Clinical Chemistry, Amsterdam Gastroenterology & Metabolism, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.

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Hermina C van Beeren Endocrine Laboratory, Department of Clinical Chemistry, Amsterdam Gastroenterology & Metabolism, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.

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Albert C W A van Wijk Department of Experimental Surgery, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands

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Andries Kalsbeek Department of Endocrinology and Metabolism, Amsterdam Gastroenterology & Metabolism, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands
Hypothalamic Integration Mechanisms, Netherlands Institute for Neuroscience, Amsterdam, The Netherlands

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Johannes A Romijn Department of Medicine, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands

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Eric Fliers Department of Endocrinology and Metabolism, Amsterdam Gastroenterology & Metabolism, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands

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Anita Boelen Endocrine Laboratory, Department of Clinical Chemistry, Amsterdam Gastroenterology & Metabolism, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.

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diiodothyronine (T 2 ). In addition to D3, hepatic sulfotransferases (Sults) and UDP-glucuronosyltranferases (UGTs) enhance the clearance of T 3 and T 4 by increasing the affinity for type 1 deiodinase and by promoting the clearance of TH via the bile and urine

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-20-0189
Volume/Issue:
Volume 9: Issue 6
Open access
Ali Abbasi MRC Epidemiology Unit, Department of Epidemiology and Department of Internal Medicine, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge Biomedical Campus, Addenbrooke's Hospital, Post Box 285, Cambridge CB2 0QQ, UK
MRC Epidemiology Unit, Department of Epidemiology and Department of Internal Medicine, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge Biomedical Campus, Addenbrooke's Hospital, Post Box 285, Cambridge CB2 0QQ, UK

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adiponectin- raising alleles Beta-carotene 1 (33) WTCCC, DGI, FUSION USA, Europe/2009 4549/5579 rs6564851/ BCMO1 Null Bilirubin 1 (11) PREVEND Netherlands/2015 210/3381 rs6742078/ UGT1A1 OR, 0.58 1- s.d. N-terminal pro B-type natriuretic peptide 1 (37

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-15-0087
Volume/Issue:
Volume 4: Issue 4
Open access
Emma Jernberg Department of Medical biosciences, Umeå University, Umeå, Sweden

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Anders Bergh Department of Medical biosciences, Umeå University, Umeå, Sweden

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Pernilla Wikström Department of Medical biosciences, Umeå University, Umeå, Sweden

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levels to be associated with expression of certain canonical AR genes, such as UBE2C , CCNA2 , UGT2B17 and C-MYC , but not with others ( KLK3 , KLK2 , NKX3-1 , TMPRSS2 and FKBP5 ) ( 65 ). Many functional studies have been performed to evaluate

Article Type:
Review Article
DOI:
https://doi.org/10.1530/EC-17-0118
Volume/Issue:
Volume 6: Issue 8
Open access
Bilal B Mughal CNRS/UMR7221, Muséum National d’Histoire Naturelle, Sorbonne Universités, Paris, France

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Jean-Baptiste Fini CNRS/UMR7221, Muséum National d’Histoire Naturelle, Sorbonne Universités, Paris, France

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Barbara A Demeneix CNRS/UMR7221, Muséum National d’Histoire Naturelle, Sorbonne Universités, Paris, France

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circulatory thyroid hormones and calcium stores in rat brain . Toxicology Letters 1996 89 29 – 33 . ( https://doi.org/10.1016/S0378-4274(96)03778-2 ) 10.1016/S0378-4274(96)03778-2 8952708 265 Giray B Caǧlayan A Erkekoǧlu P HIncal F. Fenvalerate

Article Type:
Review Article
DOI:
https://doi.org/10.1530/EC-18-0029
Volume/Issue:
Volume 7: Issue 4
Open access