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Eric Seidel, Gudrun Walenda, Clemens Messerschmidt, Benedikt Obermayer, Mirko Peitzsch, Paal Wallace, Rohini Bahethi, Taekyeong Yoo, Murim Choi, Petra Schrade, Sebastian Bachmann, Gerhard Liebisch, Graeme Eisenhofer, Dieter Beule and Ute I Scholl

, such as STAR , CYP11B1 and CYP11B2 , and a reduced activity of cytochrome c oxidase ( 12 ). More recently, inhibition of the microsomal sterol-o-acyl transferase 1 (SOAT1, also known as ACAT-1) has been suggested as the principal mode of action ( 13

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Robert I Menzies, Xin Zhao, Linda J Mullins, John J Mullins, Carolynn Cairns, Nicola Wrobel, Donald R Dunbar, Matthew A Bailey and Christopher J Kenyon

. ( doi:10.1016/j.mce.2012.10.012 ) 23089211 10.1016/j.mce.2012.10.012 38 Rogers MA Liu J Song BL Li BL Chang CC Chang TY. Acyl-CoA:cholesterol acyltransferases (ACATs/SOATs): Enzymes with multiple sterols as substrates and as