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in GDM such as 8-isoprostane (8IsoP), TNF-α, and IL-10 have been studied in a very limited number of reports, in which the results are contradictory, though some showed higher levels of oxidative stress markers in pregnancies with GDM ( 9 , 10 ). P-selectin
Department of Endocrinology and Diabetes, Pakistan Kidney and Liver Institute and Research Centre, Knowledge City, Lahore, Pakistan
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Division of Bone Diseases, Geneva University Hospitals and Faculty of Medicine, University of Geneva, Geneva, Switzerland
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treatment with exenatide resulted in reductions in serum ICAM-1, p-selectin and e-selectin, although no pronounced changes were seen in endothelial function ( 25 ). Empagliflozin is a sodium-glucose cotransporter 2 (SGLT-2) inhibitor used in the treatment
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Division of Vascular Medicine, Department of Internal Medicine, Radboud University Medical Center, Nijmegen, The Netherlands
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= 71) P Sex: male 20 36 1.0 Age (years) 51.9 (14.3) 54.5 (12.1) 0.33 Height (m) 1.75 (0.09) 1.76 (0.11) 0.73 Weight (kg) 81.2 (54.8–129.8) 83.7 (51.4–150.8) 0.06 BMI (kg/m 2 ) 27.07 (18
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intracellular adhesion molecule 1 (ICAM-1) by 22% and 20%, respectively ( Fig. 2A ). Vascular adhesion molecule was also reduced by 50% and 43%, respectively ( Fig. 2B ). The levels of other adhesion molecules, P-selectin and Endothelin-1 (ET-1), remained
Disciplina de Endocrinologia, Faculdade de Ciências Médicas da Santa Casa de São Paulo, São Paulo, São Paulo, Brazil
Unidade de Endocrinologia do Desenvolvimento, Laboratorio de Hormonios e Genetica Molecular LIM/42, Disciplina de Endocrinologia, Faculdade de Medicina, Universidade de São Paulo, São Paulo, São Paulo, Brazil
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factors. Since we tested associations with clinical parameters for multiple SNPs ( n = 5), we applied Bonferroni’s correction for the P values and only associations with P value <0.01 were considered significant. Haplotype blocks were constructed by
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://doi.org/10.3390/ijms20205214 ) 25 Petramala L Iacobellis G Carnevale R Marinelli C Zinnamosca L Concistrè A Galassi M Iannucci G Lucia P Pignatelli P Enhanced soluble serum CD40L and serum P-selectin levels in primary aldosteronism
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Bioinformatics Research Center, North Carolina State University, Raleigh, North Carolina, USA
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Center for Human Health and the Environment, North Carolina State University, Raleigh, North Carolina, USA
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Center for Human Health and the Environment, North Carolina State University, Raleigh, North Carolina, USA
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selectin P ( Selp ). Similarly, placental upregulation of both 11-β-hydroxysteroid dehydrogenase 1 and 2 ( Hsd11b1 and Hsd11b2 ), which are responsible for the inactivation of maternal cortisol ( 80 ), was observed in the high-dose group, providing
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multiple groups. Logistic regression was applied to determine the correlation of RAIU with neutropenia. P < 0.05 was considered statistically significant. All statistical analyses were performed using SPSS version 23.0 for Windows (IBM). Results
Department of Clinical Biochemistry and Laboratory Medicine, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran
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Department of Reproductive Biology, Faculty of Advanced Medical Sciences, Tabriz University of Medical Sciences, Tabriz, Iran
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Stem Cell Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
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have a role in cellular adhesion (e.g. integrins, selectins, and cadherins) ( 2 , 3 ). It has been documented that adipose tissue-derived factors can also affect implantation ( 6 , 7 ). Adipose tissue acts as an endocrine tissue and secretes hormone
Instituto de Investigación en Biomedicina de Buenos Aires – CONICET, Departamento de Fisiología, Partner Institute of the Max Planck Society, Buenos Aires, Argentina
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Instituto de Investigación en Biomedicina de Buenos Aires – CONICET, Departamento de Fisiología, Partner Institute of the Max Planck Society, Buenos Aires, Argentina
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genes such as inflammatory cytokines (e.g. IL1β, IL6, and TNFα), cytokine receptors, adhesion molecules (e.g. ICAM1, VCAM, and E-selectin), and chemotactic proteins and thus are indispensable for the propagation of inflammation (29, 33) . All of these