Department of Nutrition, School of Public Health, Sun Yat-Sen University, Guangzhou, People’s Republic of China
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Guangdong Provincial Key Laboratory of Food, Nutrition and Health, Guangzhou, People’s Republic of China
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Guangdong Provincial Key Laboratory of Food, Nutrition and Health, Guangzhou, People’s Republic of China
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Introduction Non-alcoholic fatty liver disease (NAFLD), which is considered to be the hepatic manifestation of the metabolic syndrome is defined as the abnormal hepatic triglyceride (TG) accumulation without excessive alcohol use. NAFLD
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factor-1 and hypoalbuminemia. Non-alcoholic fatty liver disease (NAFLD) affecting multiple extrahepatic organs is considered a multi-system disease ( 2 ). Recent studies have shown that NAFLD is a high risk factor for osteoporosis ( 3 ). Several studies
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Introduction Nonalcoholic fatty liver disease (NAFLD) is a manifestation of the metabolic syndrome and is associated with very common conditions such as obesity, type 2 diabetes, hypertension, dyslipidemia, and atherosclerosis (1) . NAFLD includes
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Institute of Clinical Biochemistry and Pathobiochemistry, German Diabetes Center at the Heinrich-Heine-University Duesseldorf, Leibniz Center for Diabetes Research, Duesseldorf, Germany
German Center for Diabetes Research (DZD), Munich-Neuherberg, Germany
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Introduction An important complication of obesity is the development of nonalcoholic fatty liver disease (NAFLD), which covers a broad histological spectrum from simple steatosis to nonalcoholic steatohepatitis (NASH), and can progress to
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Introduction The increasing worldwide prevalence of obesity and type 2 diabetes, which are closely associated with the development of NAFLD, has become a major healthcare problem ( 1 ). NAFLD encompasses a broad spectrum of disorders ranging
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Diabetes Center, Faculty of Medicine, University of Geneva, Geneva, Switzerland
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Introduction Nonalcoholic steatohepatitis (NASH) is part of a disease spectrum, nonalcoholic fatty liver disease (NAFLD), which ranges from simple steatosis to fibrosis and ultimately cirrhosis ( 1 , 2 , 3 , 4 ). NASH is, therefore, a
Centre for Biological Timing, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK
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Diabetes, Endocrinology and Metabolism Centre, Manchester University NHS Foundation Trust, NIHR Manchester Biomedical Research Centre, Manchester Academic Health Science Centre, Manchester, UK
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Oxford Liver Unit, Oxford University Hospitals NHS Foundation Trust, John Radcliffe Hospital, UK
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NIHR Oxford Health Biomedical Research Centre, and NIHR Oxford Biomedical Research Centre, John Radcliffe Hospital, Oxford, UK
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NIHR Oxford Health Biomedical Research Centre, and NIHR Oxford Biomedical Research Centre, John Radcliffe Hospital, Oxford, UK
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-alcoholic fatty liver disease (NAFLD). NAFLD seldom presents as a medical issue but can be detected on routine screening by detection of raised liver enzymes, or altered liver imaging parameters. NAFLD affects over 25% of the worldwide adult population, and the
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Department of Zoology, Islamia College Peshawar (CU), Peshawar, Pakistan
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DZHK (German Centre for Cardiovascular Research), Partner Site Greifswald, University Medicine, Greifswald, Germany
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Introduction Non-alcoholic fatty liver disease (NAFLD) is a common finding in individuals with obesity or type 2 diabetes mellitus and its prevalence is steeply increasing worldwide ( 1 ). Recent meta-analyses of observational studies revealed
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Department of Endocrinology, The First Hospital of Lanzhou University, Lanzhou, Gansu, China
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Department of Endocrinology, The First Hospital of Lanzhou University, Lanzhou, Gansu, China
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Department of Endocrinology, The First Hospital of Lanzhou University, Lanzhou, Gansu, China
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Introduction Non-alcoholic fatty liver disease (NAFLD), which is the excessive deposition of fat (>5% of the liver weight) in liver cells without causes such as heavy drinking, hypothyroidism, or drugs, is considered a liver manifestation of
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Betty and Guy Beatty Center for Integrated Research, Inova Health System, Falls Church, Virginia, USA
Inova Medicine, Inova Health System, Falls Church, Virginia, USA
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Introduction Nonalcoholic fatty liver disease (NAFLD) and its subtype of nonalcoholic steatohepatitis (NASH) were first described in the 1980s, coinciding with a rapid rise in epidemic of obesity ( 1 , 2 ). Increasingly, NAFLD has been