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Marko Stojanovic, Zida Wu, Craig E Stiles, Dragana Miljic, Ivan Soldatovic, Sandra Pekic, Mirjana Doknic, Milan Petakov, Vera Popovic, Christian Strasburger and Márta Korbonits

s.e. (age and BMI) or as % (gender). a t -test; b Chi-square test. GHD was defined by the GH peak in insulin tolerance test (ITT) <3.0 ng/mL or in the presence of multiple pituitary hormone deficiencies and IGF-1 below the age- and

Open access

Julia Modesto Vicente, Junia Carolina Santos-Silva, Caio Jordão Teixeira, Dailson Nogueira de Souza, Jean Franciesco Vettorazzi, Fabiola Sales Furtuoso, Isabel Gouveia Adabo, Fabio Takeo Sato, Marco Aurélio Ramirez Vinolo, Everardo Magalhães Carneiro, Silvana Bordin and Gabriel Forato Anhê

glucose tolerance at the ipGTT. The constant rate of glucose disappearance (K ITT ) was calculated using the formula 0.693/half-life. The glucose half-life was calculated from the slope of the least-squares analysis of the blood glucose concentrations

Open access

Wenqi Yang, Ling Liu, Yuan Wei, Chunlu Fang, Fu Zhou, Jinbao Chen, Qinghua Han, Meifang Huang, Xuan Tan, Qiuyue Liu, Qiang Pan, Lu Zhang, Xiaojuan Lei and Liangming Li

from the tail vein at various time points (0, 15, 30, 60, 90, 120 min) for glucose determination using the Accu-Chek Performa glucometer (Roche). Insulin tolerance test (ITT) ITT was performed after 10 weeks of diet and exercise intervention

Open access

Alessandro Ciresi, Stefano Radellini, Valentina Guarnotta, Maria Grazia Mineo and Carla Giordano

respond to the glucagon stimulation test (GST) and the insulin tolerance test (ITT), with GH peaks below 8 µg/L according to the Italian criteria of appropriateness of use and reimbursement of GHT in children ( 18 ). Neuroimaging, with magnetic resonance

Open access

Ozlem Atan Sahin, Damla Goksen, Aysel Ozpinar, Muhittin Serdar and Huseyin Onay

associations between DM1 and VDR genotypes, Bsm IBB ( P  < 0.05), Bsm IBb ( P  < 0.05), Bsm Ibb ( P  < 0.05), Taq ITT ( P  < 0.05) and Taq Itt ( P  < 0.05) in children. This present meta-analysis involves a large data set to investigate the associations

Open access

Changwei Liu, Jingwen Wang, Yuanyuan Wan, Xiaona Xia, Jian Pan, Wei Gu and Mei Li

://doi.org/10.1186/s12887-017-0834-8 ) 4 Itoh A Ridgway WM. Targeting innate immunity to downmodulate adaptive immunity and reverse type 1 diabetes . ImmunoTargets and Therapy 2017 6 31 – 38 . ( https://doi.org/10.2147/ITT.S117264 ) 5 Muñoz GA

Open access

Jothydev Kesavadev, Pradeep Babu Sadasivan Pillai, Arun Shankar, Gopika Krishnan and Sunitha Jothydev

on the per-protocol (PP) dataset (all randomized subjects who completed study as per study protocol). Safety analyses were conducted on the intent-to-treat (ITT) dataset (all randomized subjects who received one or more doses of study drug). All

Open access

Yael Sofer, Nava Nevo, Michal Vechoropoulos, Gabi Shefer, Etty Osher, Nathan Landis, Karen Tordjman, Geoffrey L Hammond and Naftali Stern

and 120 min after the injection of glucose. Similarly, an insulin tolerance test (ITT) was carried out with an intra-peritoneal injection of insulin (Humalog, 0.75 U/kg; Eli Lilly) and subsequent measurement of glucose at same time points. Blood

Open access

Shane M Regnier, Andrew G Kirkley, Daniel Ruiz, Wakanene Kamau, Qian Wu, Kurunthachalam Kannan and Robert M Sargis

manufacturer’s instructions (Millipore). Intraperitoneal insulin tolerance test (IP-ITT) After 10 weeks of exposure, mice were fasted for 3 h beginning at 09:00 h. Fasting blood glucose levels were measured as above. Mice then received an IP injection

Open access

Guillem Cuatrecasas, Hatice Kumru, M Josep Coves and Joan Vidal

be quite frequent (13/19) following traumatic complete SCI and that GH replacement therapy improves quality of life and, strikingly, sensory deficit below SCI. Insulin tolerance test (ITT) should have been the gold standard method to assess GH