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-protein-coupled receptor 119 (GPR119). This receptor is expressed in gut enteroendocrine cells (5) , whereby activation has been shown to result in increased release of GLP1 (6, 7) . GPR119 protein is also localized to islet β-cells (6) , and consequently, GPR119
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School of Science and Health, Western Sydney University, Campbelltown, New South Wales, Australia
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The Florey Institute of Neuroscience and Mental Health, Parkville, Melbourne, Victoria, Australia
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Australian Institute for Musculoskeletal Science (AIMSS), College of Health and Biomedicine, Victoria University, Melbourne, Victoria, Australia
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School of Environment and Sciences, Griffith University, Nathan, Queensland, Australia
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McKillop AM Moran BM Abdel-Wahab YH Gormley NM Flatt PR. Metabolic effects of orally administered small-molecule agonists of GPR55 and GPR119 in multiple low-dose streptozotocin-induced diabetic and incretin-receptor-knockout mice . Diabetologia 2016
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cancer cells via the G protein-coupled receptor GPR40 . Journal of Biological Chemistry 2005 280 13285 – 13291 . ( https://doi.org/10.1074/jbc.M410922200 ) 10.1074/jbc.M410922200 7 McArthur MJ Atshaves BP Frolov A Foxworth WD Kier AB Schroeder F
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, also known as G protein-coupled receptor 30 (GPR30), used to be considered an orphan receptor. Later, two groups independently proved that GPER binds to and is activated by estradiol, and in response, initiates intracellular signaling cascades ( 10
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Department of Pharmacology, Dalhousie University, Halifax, Nova Scotia, Canada
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group ( Table 3 ). When data from all eight subjects were combined, the mean serum total chemerin concentration (14.4 ± 3.9) was significantly higher than the mean plasma total chemerin concentration (11.9 ± 3.3), P = 0.01 paired t -test. We attempted
Department of Clinical Biochemistry and Laboratory Medicine, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran
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Department of Reproductive Biology, Faculty of Advanced Medical Sciences, Tabriz University of Medical Sciences, Tabriz, Iran
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Stem Cell Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
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Department of Clinical Biochemistry and Laboratory Medicine, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran
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adhesion (mouse) ND (118) Involving in decidualization (murine) ND (119) Establishing placenta by involvement in hypertrophy and proliferation of the endometrial epithelium, growth and migration of cytotrophoblast, and maternal
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system includes kisspeptin and its receptor GPR54 (KISS1R) ( 18 ). Kisspeptins, a neuropeptide encoded by the Kiss1 gene, act as crucial central regulators of GnRH release to facilitate GnRH secretion and play an essential role in activating the
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Serviço de Endocrinologia, Departamento de Endocrinologia, Faculdade de Medicina da Universidade do Porto, Al. Prof. Hernâni Monteiro, 4200-319 Porto, Portugal
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(TDS) (117) , as they probably arise from intrauterine disruption of proper testicular development and function (118) under ED exposure (119) . Impaired Leydig cells function is the main cellular trait of TDS (120, 121) . In mild cases, men have
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Left nasal cavity 24 Ga-DOTANOC 1310 Ru/mL (N: 0–150) 109 Ru/mL (1 month post surgery) No – Hemangiopericytoma 119 Gonzalez (95) 42 M Nasofrontal sinus 72 PE 75.9 pg/mL (N: 8–54) 8.4 pg/mL No – PMTMCT 120
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; Exploring cytokine or chemical induced safe and effective transition is prospective 4–8 Wnt signaling pathway (119, 120, 121) Biliary cells Transduction of pancreatic transcription factors Pdx1 , NeuroD1 , Ngn3 , MafA or Pdx1 / VP16