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Phosphorylated EGFR (p-Tyr1068) and IGFR (p-Y1135/1136), p-VEGFR 2 (Tyr1175) levels were measured using the AlphaScreen SureFire assays (Perkin Elmer). Briefly, 2 × 10 4 cells/well were seeded in complete medium, in 96-well plates and, after overnight attachment
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experiments and are expressed as mean fluorescent intensities of paxillin above unstimulated cells. **P < 0.01 , ***P < 0.001. Role of EGFR on migration and focal contacts formation induced by OA We studied the role of EGFR on cell migration
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shown that both subclinical hypothyroidism and hypothyroidism were associated with elevated serum creatinine, decreased estimated glomerular filtration rate (eGFR) and increased risk of chronic kidney disease (CKD) ( 4 , 5 , 6 , 7 ). Moreover, the
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Vascular Research Group, School of Community Based Medicine, Centre for Integrated Genomic Medical Research, Cardiovascular Research Group, Endocrinology and Diabetes, Salford R&D, Department of Endocrinology and Diabetes, Faculty of Medical, Human and Life Sciences, The University of Manchester, Manchester M13 9PT, UK
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Vascular Research Group, School of Community Based Medicine, Centre for Integrated Genomic Medical Research, Cardiovascular Research Group, Endocrinology and Diabetes, Salford R&D, Department of Endocrinology and Diabetes, Faculty of Medical, Human and Life Sciences, The University of Manchester, Manchester M13 9PT, UK
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measurements for the year 2002 were used as baseline data. Estimated GFR (eGFR) were calculated from serum creatinine measurements according to gender-specific modification of diet in renal disease (MDRD) equations (13) . Serum creatinine measurements were
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, eGFR creatinine, estimated glomerular filtration rate (eGFR) cystatin C and procollagen type 1 N-terminal propetide (P1NP)) in patients with pHPT subjected to parathyroidectomy. Patients and methods The study includes 38 patients (31 females
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Department of Health Sciences, Department of Epidemiology and Biostatistics, Department of Public Health, Department of General Practice, Department of Internal Medicine and Cardiovascular Research Institute Maastricht, Department of Internal Medicine, Faculty of Earth and Life Sciences, EMGO Institute for Health and Care Research, VU University Amsterdam, De Boelelaan 1085, 1081 HV Amsterdam, The Netherlands
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(eGFR) was calculated using serum creatinine values – determined using the Jaffé method – according to the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equation (18) . Subjects filled out questionnaires to obtain self-reported information
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Endocrine Unit 2, Department of Clinical and Experimental Medicine, Laboratory of Chemistry and Endocrinology, University Hospital of Pisa, Via Paradisa 2, 56124 Pisa, Italy
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starts to raise when serum 25OHD concentration is below this value (14, 15) . The estimated glomerular filtration rate (eGFR) was evaluated from serum creatinine (16) . The diagnosis of PHPT was based on increased alb-sCa, associated with elevated or
Tanaka Medical Clinic, Yoichi, Japan
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Institute for Clinical Research, NHO Kure Medical Center and Chugoku Cancer Center, Hiroshima, Japan
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Department of Cellular Physiology and Signal Transduction, Sapporo Medical University School of Medicine, Sapporo, Japan
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glucose and lipid metabolism were measured as previously described ( 27 ). The estimated glomerular filtration rate (eGFR) for Japanese individuals was calculated using an equation ( 32 ). A self-administered questionnaire survey was performed to obtain
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/urinary creatinine level. eGFR was calculated based on the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) creatinine–cystatin C equation (2012) ( 17 ). Diagnostic criteria of DKD According to the American Diabetes Association Consensus in 2014
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Department of Endocrinology, Quanzhou First Hospital Affiliated to Fujian Medical University, Quanzhou, China
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(SCR in μmol/L), blood uric acid (UA in μmol/L), glycated hemoglobin (HbA1c in %), urinary microalbumin (mg/dL), urinary creatinine (μmol/L), and calculate urinary albumin to creatinine ratio (ACR in mg/g) and glomerular filtration rate (eGFR in mL