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. Desmopressin (DDAVP, a synthetic AVP analogue) reduces uncontrolled water excretion in CDI and is commonly used in treatment. Critically, loss of thirst perception (through primary pathology or reduced consciousness) or limited access to water (through non
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/dL) and peak plasma ACTH >12 pmol/L (54 pg/mL) Peak serum cortisol >580 nmol/L (21 μg/dL) and peak plasma ACTH >10 pmol/L (45 pg/mL) 96.6 90 100 83.3 Moro M, 2000 (71) PCS 30 CD 76 SO 36 CT 31 PCS 30 CD 20 (mild) DDAVP Serial blood samples
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at the Academic Medical Centre (AMC) of the University of Amsterdam between 1994 and 2011 were included. Hypercalcemia and hyperglycemia were excluded in all subjects. None of the subjects used desmopressin (DDAVP) or drugs that may interfere with the
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Department of Clinical Sciences and Community Health, University of Milan, Milan, Italy
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, respectively, and 10–80 μg/24 h and 17–136 µg/24 h for UFC with immunometric and chemiluminescent assays, respectively; normal range for serum cortisol is 5–25 μg/dL with either assay. Statistical analyses The ACTH and cortisol responses to DDAVP were
Collaborating Center for the WHO Family of International Classifications in China, Beijing, China
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Key Laboratory of Endocrinology of National Health Commission of People’s Republic of China, Beijing, China
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China Pituitary Disease Registry Center, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China
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China Pituitary Disease Registry Center, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China
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China Pituitary Disease Registry Center, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China
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-enhanced MRI of the pituitary glands and plain and contrasted enhanced computed tomography (CT) of the adrenal, thoracoabdominal and pelvic areas. Since bilateral inferior petrosal sinus sampling (BIPSS) with desmopressin (DDAVP) has been demonstrated to have
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.1016/j.wneu.2017.01.075 ) 3 Sheehan JM Sheehan JP Douds GL Page RB . DDAVP use in patients undergoing transsphenoidal surgery for pituitary adenomas . Acta Neurochirurgica 2006 148 287 – 291 ; discussion 291. ( https://doi.org/10.1007/s00701
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(basal and stimulated C/P ratios) adopted for the use of DDAVP in BIPSS are different among the studies and based on a very limited number of patients with EAS, it can be concluded that larger confirmatory studies have to be performed before this