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S E Baldeweg Department of Diabetes and Endocrinology, University College London NHS Foundation Trust and Univeristy College London, London, UK

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S Ball Department of Medicine and Endocrinology, Manchester University Foundation Trust & Manchester Academic Health Science Centre Manchester, Manchester, UK

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A Brooke Royal Devon and Exeter NHS Foundation Trust, Exeter, UK

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H K Gleeson Department of Endocrinology, Queen Elizabeth Hospital, Birmingham, UK

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M J Levy University of Leicester and University of Leicester Hospitals Trust, Leicester, UK

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M Prentice Croydon Health Services NHS Trust, Croydon, UK

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J Wass Department of Endocrinology, Oxford Centre for Diabetes, Endocrinology & Metabolism, Oxford, UK

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the Society for Endocrinology Clinical Committee The Society for Endocrinology, Starling House, 1600 Bristol Parkway North, Bristol, UK

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. Desmopressin (DDAVP, a synthetic AVP analogue) reduces uncontrolled water excretion in CDI and is commonly used in treatment. Critically, loss of thirst perception (through primary pathology or reduced consciousness) or limited access to water (through non

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Carla Scaroni Dipartimento di Medicina, U.O.C. Endocrinologia, Università di Padova, Padova, Italy

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Nora M Albiger Dipartimento di Medicina, U.O.C. Endocrinologia, Università di Padova, Padova, Italy

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Serena Palmieri Department of Clinical Sciences and Community Health, University of Milan, Fondazione IRCCS Cà Granda-Ospedale Maggiore Policlinico, Milan, Italy

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Davide Iacuaniello Dipartimento di Medicina Clinica e Chirurgia, Sezione di Endocrinologia, Università Federico II di Napoli, Napoli, Italy

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Chiara Graziadio Department of Experimental Medicine, University La Sapienza, Rome, Italy

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Luca Damiani Department of Medical Sciences, Endocrinology and Internal Medicine Section, University of Ferrara, Ferrara, Italy

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Marialuisa Zilio Dipartimento di Medicina, U.O.C. Endocrinologia, Università di Padova, Padova, Italy

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Antonio Stigliano Department of Clinical and Molecular Medicine, Sant’Andrea Hospital, University La Sapienza, Rome, Italy

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Annamaria Colao Dipartimento di Medicina Clinica e Chirurgia, Sezione di Endocrinologia, Università Federico II di Napoli, Napoli, Italy

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Rosario Pivonello Dipartimento di Medicina Clinica e Chirurgia, Sezione di Endocrinologia, Università Federico II di Napoli, Napoli, Italy

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the Altogether to Beat Cushing’s Syndrome (ABC) study group
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/dL) and peak plasma ACTH >12 pmol/L (54 pg/mL) Peak serum cortisol >580 nmol/L (21 μg/dL) and peak plasma ACTH >10 pmol/L (45 pg/mL) 96.6 90 100 83.3 Moro M, 2000 (71) PCS 30 CD 76 SO 36 CT 31 PCS 30 CD 20 (mild) DDAVP Serial blood samples

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M de Fost Department of Endocrinology and Metabolism, Laboratory of Endocrinology, Room F5‐164

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S M Oussaada Department of Endocrinology and Metabolism, Laboratory of Endocrinology, Room F5‐164

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E Endert Department of Endocrinology and Metabolism, Laboratory of Endocrinology, Room F5‐164

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G E Linthorst Department of Endocrinology and Metabolism, Laboratory of Endocrinology, Room F5‐164

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M J Serlie Department of Endocrinology and Metabolism, Laboratory of Endocrinology, Room F5‐164

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M R Soeters Department of Endocrinology and Metabolism, Laboratory of Endocrinology, Room F5‐164

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J H DeVries Department of Endocrinology and Metabolism, Laboratory of Endocrinology, Room F5‐164

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P H Bisschop Department of Endocrinology and Metabolism, Laboratory of Endocrinology, Room F5‐164

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E Fliers Department of Endocrinology and Metabolism, Laboratory of Endocrinology, Room F5‐164

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at the Academic Medical Centre (AMC) of the University of Amsterdam between 1994 and 2011 were included. Hypercalcemia and hyperglycemia were excluded in all subjects. None of the subjects used desmopressin (DDAVP) or drugs that may interfere with the

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Alberto Giacinto Ambrogio Neuroendocrinology Research Laboratory, Istituto Auxologico Italiano IRCCS, Milan, Italy

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Massimiliano Andrioli Neuroendocrinology Research Laboratory, Istituto Auxologico Italiano IRCCS, Milan, Italy

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Martina De Martin Neuroendocrinology Research Laboratory, Istituto Auxologico Italiano IRCCS, Milan, Italy

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Francesco Cavagnini Neuroendocrinology Research Laboratory, Istituto Auxologico Italiano IRCCS, Milan, Italy

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Francesca Pecori Giraldi Neuroendocrinology Research Laboratory, Istituto Auxologico Italiano IRCCS, Milan, Italy
Department of Clinical Sciences and Community Health, University of Milan, Milan, Italy

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, respectively, and 10–80 μg/24 h and 17–136 µg/24 h for UFC with immunometric and chemiluminescent assays, respectively; normal range for serum cortisol is 5–25 μg/dL with either assay. Statistical analyses The ACTH and cortisol responses to DDAVP were

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Jingya Zhou Department of Medical Records, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
Collaborating Center for the WHO Family of International Classifications in China, Beijing, China

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Meng Zhang Department of Medical Records, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
Collaborating Center for the WHO Family of International Classifications in China, Beijing, China

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Lin Lu Department of Endocrinology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
Key Laboratory of Endocrinology of National Health Commission of People’s Republic of China, Beijing, China

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Xiaopeng Guo Department of Neurosurgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
China Pituitary Disease Registry Center, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China

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Lu Gao Department of Neurosurgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
China Pituitary Disease Registry Center, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China

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Weigang Yan Department of Urology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China

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Haiyu Pang Central Research Laboratory, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
Clinical Epidemiology Unit, International Epidemiology Network, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China

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Yi Wang Department of Medical Records, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
Collaborating Center for the WHO Family of International Classifications in China, Beijing, China

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Bing Xing Department of Neurosurgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
China Pituitary Disease Registry Center, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China

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-enhanced MRI of the pituitary glands and plain and contrasted enhanced computed tomography (CT) of the adrenal, thoracoabdominal and pelvic areas. Since bilateral inferior petrosal sinus sampling (BIPSS) with desmopressin (DDAVP) has been demonstrated to have

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Liang Xue Fuzong Clinical Medical College of Fujian Medical University, Fuzhou, China
Department of Neurosurgery, 900TH Hospital of the Joint Logistics Support Force, Fuzhou, Fujian, China

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Jianwu Wu Department of Neurosurgery, 900TH Hospital of the Joint Logistics Support Force, Fuzhou, Fujian, China

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Jie Chen Department of Radiology, 900TH Hospital of the Joint Logistics Support Force, Fuzhou, Fujian, China

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Yongkai Yang Department of Neurosurgery, Affiliated Fuzhou First Hospital of Fujian Medical University, Fuzhou, Fujian, China

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.1016/j.wneu.2017.01.075 ) 3 Sheehan JM Sheehan JP Douds GL Page RB . DDAVP use in patients undergoing transsphenoidal surgery for pituitary adenomas . Acta Neurochirurgica 2006 148 287 – 291 ; discussion 291. ( https://doi.org/10.1007/s00701

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Benedetta Zampetti Department of Endocrinology, Ospedale Niguarda, Milano, Italy

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Erika Grossrubatscher Department of Endocrinology, Ospedale Niguarda, Milano, Italy

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Paolo Dalino Ciaramella Department of Endocrinology, Ospedale Niguarda, Milano, Italy

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Edoardo Boccardi Department of Neuroradiology, Ospedale Niguarda, Milano, Italy

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Paola Loli Department of Endocrinology, Ospedale Niguarda, Milano, Italy

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(basal and stimulated C/P ratios) adopted for the use of DDAVP in BIPSS are different among the studies and based on a very limited number of patients with EAS, it can be concluded that larger confirmatory studies have to be performed before this

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