Marra Jai Aghajani
Marra Jai Aghajani
Ingham Institute for Applied Medical Research, Liverpool, New South Wales, Australia
School of Medicine, Western Sydney University, Campbelltown, New South Wales, Australia
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School of Medicine, Western Sydney University, Campbelltown, New South Wales, Australia
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Tao Yang
Tao Yang
School of Medicine, Western Sydney University, Campbelltown, New South Wales, Australia
Saint Vincent’s Clinical School, UNSW Sydney, Sydney, Australia
SydPath, Saint Vincent’s Hospital, Sydney, Australia
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Saint Vincent’s Clinical School, UNSW Sydney, Sydney, Australia
SydPath, Saint Vincent’s Hospital, Sydney, Australia
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Ulf Schmitz
Ulf Schmitz
Computational BioMedicine Laboratory Centenary Institute, The University of Sydney, Camperdown, New South Wales, Australia
Gene & Stem Cell Therapy Program Centenary Institute, The University of Sydney, Camperdown, New South Wales, Australia
Faculty of Medicine & Health, The University of Sydney, Camperdown, New South Wales, Australia
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Gene & Stem Cell Therapy Program Centenary Institute, The University of Sydney, Camperdown, New South Wales, Australia
Faculty of Medicine & Health, The University of Sydney, Camperdown, New South Wales, Australia
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Alexander James
Alexander James
Ingham Institute for Applied Medical Research, Liverpool, New South Wales, Australia
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Charles Eugenio McCafferty
Charles Eugenio McCafferty
Ingham Institute for Applied Medical Research, Liverpool, New South Wales, Australia
School of Medicine, Western Sydney University, Campbelltown, New South Wales, Australia
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School of Medicine, Western Sydney University, Campbelltown, New South Wales, Australia
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Paul de Souza
Paul de Souza
Ingham Institute for Applied Medical Research, Liverpool, New South Wales, Australia
School of Medicine, Western Sydney University, Campbelltown, New South Wales, Australia
School of Medicine, University of Wollongong, New South Wales, Australia
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School of Medicine, Western Sydney University, Campbelltown, New South Wales, Australia
School of Medicine, University of Wollongong, New South Wales, Australia
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Navin Niles
Navin Niles
Ingham Institute for Applied Medical Research, Liverpool, New South Wales, Australia
School of Medicine, Western Sydney University, Campbelltown, New South Wales, Australia
Department of Head & Neck Surgery, Liverpool Hospital, Liverpool, New South Wales, Australia
Department of Clinical Medicine, Faculty of Medicine and Health Sciences, Macquarie University, Sydney, Australia
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School of Medicine, Western Sydney University, Campbelltown, New South Wales, Australia
Department of Head & Neck Surgery, Liverpool Hospital, Liverpool, New South Wales, Australia
Department of Clinical Medicine, Faculty of Medicine and Health Sciences, Macquarie University, Sydney, Australia
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Tara L Roberts
Tara L Roberts
Ingham Institute for Applied Medical Research, Liverpool, New South Wales, Australia
School of Medicine, Western Sydney University, Campbelltown, New South Wales, Australia
South West Sydney Clinical School, UNSW Sydney, Sydney, Australia
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School of Medicine, Western Sydney University, Campbelltown, New South Wales, Australia
South West Sydney Clinical School, UNSW Sydney, Sydney, Australia
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blockade ( 23 ). However, the relationship between T cell infiltrate, PD-L1 and EMT status, and their influence on the progression and metastasis of human thyroid cancer, has yet to be investigated. To address this issue, we examined the expression of CD8
Borros Arneth
Borros Arneth
Institute of Laboratory Medicine and Pathobiochemistry, Molecular Diagnostics, University Hospital of the Universities of Giessen and Marburg, UKGM, Justus Liebig University, Giessen, Giessen, Germany
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DM patients, type 2 DM patients and healthy subjects were incubated overnight with insulin or GAD. Then, aliquots of the whole blood samples were analyzed by flow cytometry, and the proportions of activated CD4+ and CD8+ T-lymphocytes were analyzed
Camila Aparecida Moma
Camila Aparecida Moma
Endocrinology Division, Department of Internal Medicine, Faculty of Medical Sciences, University of Campinas, Campinas, São Paulo, Brazil
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Icléia Siqueira Barreto
Icléia Siqueira Barreto
Department of Pathology, Faculty of Medical Sciences, University of Campinas, Campinas, São Paulo, Brazil
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Ligia Vera Montali Assumpção
Ligia Vera Montali Assumpção
Endocrinology Division, Department of Internal Medicine, Faculty of Medical Sciences, University of Campinas, Campinas, São Paulo, Brazil
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Denise Engelbrecht Zantut-Wittmann
Denise Engelbrecht Zantut-Wittmann
Endocrinology Division, Department of Internal Medicine, Faculty of Medical Sciences, University of Campinas, Campinas, São Paulo, Brazil
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required ( 18 ). When signals from MHC class I and costimulatory proteins occur, it is possible to activate CD8+ T lymphocytes, leading to apoptosis of tumor cells. However, when MHC class II signaling occurs, Th1 (hypersensitivity), Th2 (antibody
Lang Qin
Lang Qin
Division of Endocrinology and Metabolism, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China
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Xiaoming Zhu
Xiaoming Zhu
Division of Endocrinology and Metabolism, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China
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Xiaoxia Liu
Xiaoxia Liu
Division of Endocrinology and Metabolism, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China
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Meifang Zeng
Meifang Zeng
Division of Endocrinology and Metabolism, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China
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Ran Tao
Ran Tao
Division of Endocrinology and Metabolism, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China
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Yan Zhuang
Yan Zhuang
Division of Endocrinology and Metabolism, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China
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Yiting Zhou
Yiting Zhou
Division of Endocrinology and Metabolism, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China
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Zhaoyun Zhang
Zhaoyun Zhang
Division of Endocrinology and Metabolism, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China
Shanghai Pituitary Tumor Center, Shanghai, China
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Shanghai Pituitary Tumor Center, Shanghai, China
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Yehong Yang
Yehong Yang
Division of Endocrinology and Metabolism, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China
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Yiming Li
Yiming Li
Division of Endocrinology and Metabolism, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China
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Yongfei Wang
Yongfei Wang
Division of Neurosurgery, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China
Shanghai Pituitary Tumor Center, Shanghai, China
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Shanghai Pituitary Tumor Center, Shanghai, China
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Hongying Ye
Hongying Ye
Division of Endocrinology and Metabolism, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China
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2 ( 8 ), insulin resistance ( 9 ) and sleep apnea ( 10 ) also play important roles in the determination of lipid abnormalities. During the past decades, multiple studies have presented the relationship between hypertension and lipid profile in non-CD
Pablo Abellán-Galiana
Pablo Abellán-Galiana
Department of Endocrinology, Hospital General Universitari de Castelló, Castellón, Spain
Department of Medicine, Universidad Cardenal Herrera-CEU, CEU Universities, Castellón, Spain
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Department of Medicine, Universidad Cardenal Herrera-CEU, CEU Universities, Castellón, Spain
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Carmen Fajardo-Montañana
Carmen Fajardo-Montañana
Department of Endocrinology, Hospital Universitario de la Ribera, Alzira, Spain
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Pedro Riesgo-Suárez
Pedro Riesgo-Suárez
Department of Neurosurgery, Hospital Universitario de la Ribera, Alzira, Spain
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Marcelino Pérez-Bermejo
Marcelino Pérez-Bermejo
Department of Nursing, Universidad Católica de Valencia, Valencia, Spain
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Celia Ríos-Pérez
Celia Ríos-Pérez
Centro de Salud Tavernes de la Valldigna, Hospital Comarcal Francesc de Borja, Gandía, Spain
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José Gómez-Vela
José Gómez-Vela
Department of Endocrinology, Hospital Universitario de la Ribera, Alzira, Spain
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Introduction Transsphenoidal surgery is the treatment of choice in Cushing’s disease (CD). Following removal of the pituitary adenoma, the remission rate varies between 25 and 100% (mean 77.8%, median 78.7%), and the recurrence rate ranges
Emmanuelle Motte
Emmanuelle Motte
UFR des Sciences de la Santé, Simone Veil, Université Versailles St-Quentin en Yvelines, Montigny le Bretonneux, France
Assistance Publique Hôpitaux de Paris (APHP), Department of Endocrinology and Diabetes for Children, Bicêtre Paris-Sud, Le Kremlin Bicêtre, France
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Assistance Publique Hôpitaux de Paris (APHP), Department of Endocrinology and Diabetes for Children, Bicêtre Paris-Sud, Le Kremlin Bicêtre, France
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Anya Rothenbuhler
Anya Rothenbuhler
Assistance Publique Hôpitaux de Paris (APHP), Department of Endocrinology and Diabetes for Children, Bicêtre Paris-Sud, Le Kremlin Bicêtre, France
APHP, Plateforme d’Expertise Maladies Rares Paris Sud, Bicêtre Paris Sud Hospital, Le Kremlin Bicêtre, France
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APHP, Plateforme d’Expertise Maladies Rares Paris Sud, Bicêtre Paris Sud Hospital, Le Kremlin Bicêtre, France
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Stephan Gaillard
Stephan Gaillard
Department of Neurosurgery, Foch Hospital, Suresnes, France
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Najiba Lahlou
Najiba Lahlou
APHP, Department of Hormonal Biology, Cochin Hospital, Paris, France
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Cécile Teinturier
Cécile Teinturier
Assistance Publique Hôpitaux de Paris (APHP), Department of Endocrinology and Diabetes for Children, Bicêtre Paris-Sud, Le Kremlin Bicêtre, France
APHP, Plateforme d’Expertise Maladies Rares Paris Sud, Bicêtre Paris Sud Hospital, Le Kremlin Bicêtre, France
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APHP, Plateforme d’Expertise Maladies Rares Paris Sud, Bicêtre Paris Sud Hospital, Le Kremlin Bicêtre, France
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Régis Coutant
Régis Coutant
Department of Pediatric Endocrinology, Angers University Hospital, Angers, France
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Agnès Linglart
Agnès Linglart
Assistance Publique Hôpitaux de Paris (APHP), Department of Endocrinology and Diabetes for Children, Bicêtre Paris-Sud, Le Kremlin Bicêtre, France
APHP, Plateforme d’Expertise Maladies Rares Paris Sud, Bicêtre Paris Sud Hospital, Le Kremlin Bicêtre, France
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APHP, Plateforme d’Expertise Maladies Rares Paris Sud, Bicêtre Paris Sud Hospital, Le Kremlin Bicêtre, France
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publications mentioning op’DDD in CD. Author Year N Op’DDD dosage (g/day) Administration Duration % of patients with UFC < 100 µg/24 h Luton ( 27 ) 1978 46 6.00 Continuous 8 months 83 Schteingart ( 29 ) 1980
Tiina Vesterinen
Tiina Vesterinen
HUSLAB, Department of Pathology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland
Institute for Molecular Medicine Finland (FIMM), Helsinki Institute of Life Science, University of Helsinki, Helsinki, Finland
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Institute for Molecular Medicine Finland (FIMM), Helsinki Institute of Life Science, University of Helsinki, Helsinki, Finland
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Teijo Kuopio
Teijo Kuopio
Department of Biological and Environmental Science, University of Jyväskylä and Department of Pathology, Central Finland Health Care District, Jyväskylä, Finland
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Maarit Ahtiainen
Maarit Ahtiainen
Department of Education and Research, Central Finland Central Hospital, Jyväskylä, Finland
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Aija Knuuttila
Aija Knuuttila
Department of Pulmonary Medicine, Heart and Lung Center, and Cancer Center, University of Helsinki and Helsinki University Hospital, Helsinki, Finland
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Harri Mustonen
Harri Mustonen
Department of Surgery, University of Helsinki and Helsinki University Hospital, Helsinki, Finland
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Kaisa Salmenkivi
Kaisa Salmenkivi
HUSLAB, Department of Pathology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland
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Johanna Arola
Johanna Arola
HUSLAB, Department of Pathology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland
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Caj Haglund
Caj Haglund
Department of Surgery, University of Helsinki and Helsinki University Hospital, Helsinki, Finland
Translational Cancer Medicine Program, Faculty of Medicine, University of Helsinki, Helsinki, Finland
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Translational Cancer Medicine Program, Faculty of Medicine, University of Helsinki, Helsinki, Finland
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). Over recent decades, several studies have shown that the immune system plays a critical role in recognizing and eliminating malignant cells. In particular, elevated levels of cytotoxic CD8 + T cells in the tumor microenvironment have been linked to a
Natalio García-Honduvilla
Natalio García-Honduvilla
Department of Medicine and Medical Specialities, Faculty of Medicine and Health Sciences, University of Alcalá, Alcalá de Henares, Madrid, Spain
Networking Biomedical Research Center on Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN), Madrid, Spain
Ramón y Cajal Institute of Sanitary Research (IRYCIS), Madrid, Spain
University Center of Defense of Madrid (CUD-ACD), Madrid, Spain
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Networking Biomedical Research Center on Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN), Madrid, Spain
Ramón y Cajal Institute of Sanitary Research (IRYCIS), Madrid, Spain
University Center of Defense of Madrid (CUD-ACD), Madrid, Spain
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Alberto Cifuentes
Alberto Cifuentes
Department of Medicine and Medical Specialities, Faculty of Medicine and Health Sciences, University of Alcalá, Alcalá de Henares, Madrid, Spain
Networking Biomedical Research Center on Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN), Madrid, Spain
Ramón y Cajal Institute of Sanitary Research (IRYCIS), Madrid, Spain
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Networking Biomedical Research Center on Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN), Madrid, Spain
Ramón y Cajal Institute of Sanitary Research (IRYCIS), Madrid, Spain
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Miguel A Ortega
Miguel A Ortega
Department of Medicine and Medical Specialities, Faculty of Medicine and Health Sciences, University of Alcalá, Alcalá de Henares, Madrid, Spain
Networking Biomedical Research Center on Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN), Madrid, Spain
Ramón y Cajal Institute of Sanitary Research (IRYCIS), Madrid, Spain
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Networking Biomedical Research Center on Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN), Madrid, Spain
Ramón y Cajal Institute of Sanitary Research (IRYCIS), Madrid, Spain
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Marta Pastor
Marta Pastor
Biopraxis Research AIE, Álava, Spain
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Garazi Gainza
Garazi Gainza
Biopraxis Research AIE, Álava, Spain
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Eusebio Gainza
Eusebio Gainza
Biopraxis Research AIE, Álava, Spain
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Julia Buján
Julia Buján
Department of Medicine and Medical Specialities, Faculty of Medicine and Health Sciences, University of Alcalá, Alcalá de Henares, Madrid, Spain
Networking Biomedical Research Center on Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN), Madrid, Spain
Ramón y Cajal Institute of Sanitary Research (IRYCIS), Madrid, Spain
University Center of Defense of Madrid (CUD-ACD), Madrid, Spain
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Networking Biomedical Research Center on Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN), Madrid, Spain
Ramón y Cajal Institute of Sanitary Research (IRYCIS), Madrid, Spain
University Center of Defense of Madrid (CUD-ACD), Madrid, Spain
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Melchor Álvarez-Mon
Melchor Álvarez-Mon
Department of Medicine and Medical Specialities, Faculty of Medicine and Health Sciences, University of Alcalá, Alcalá de Henares, Madrid, Spain
Networking Biomedical Research Center on Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN), Madrid, Spain
Ramón y Cajal Institute of Sanitary Research (IRYCIS), Madrid, Spain
University Center of Defense of Madrid (CUD-ACD), Madrid, Spain
Immune System Diseases-Rheumatology and Oncology Service, University Hospital Príncipe de Asturias, Alcalá de Henares, Madrid, Spain
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Networking Biomedical Research Center on Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN), Madrid, Spain
Ramón y Cajal Institute of Sanitary Research (IRYCIS), Madrid, Spain
University Center of Defense of Madrid (CUD-ACD), Madrid, Spain
Immune System Diseases-Rheumatology and Oncology Service, University Hospital Príncipe de Asturias, Alcalá de Henares, Madrid, Spain
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4 + T lymphocytes and CD8 + T lymphocytes, was assessed immunohistochemically using the avidin–biotin complex technique in animals from Protocol 2. Macrophages were detected using a mouse anti-CD68 monoclonal antibody (AbD Serotec, Kidlington, UK
L Ahlkvist
L Ahlkvist
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K Brown
K Brown
Department of Clinical Sciences, GlaxoSmithKline, Biomedical Center, C11, Lund University, SE 22184 Lund, Sweden
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B Ahrén
B Ahrén
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glucose. In the first experiment, the direct effect of GSK706A on insulin secretion was determined by incubating isolated islets from mice fed the CD and HFD in different concentrations of glucose (2.8, 5.6, 8.3, 11.1, and 16.7 mmol/l), with or without
Prachi Bansal
Prachi Bansal
Department of Endocrinology, Seth G.S. Medical College and KEM Hospital, Mumbai, Maharashtra, India
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Anurag Lila
Anurag Lila
Department of Endocrinology, Seth G.S. Medical College and KEM Hospital, Mumbai, Maharashtra, India
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Manjunath Goroshi
Manjunath Goroshi
Department of Endocrinology, Seth G.S. Medical College and KEM Hospital, Mumbai, Maharashtra, India
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Swati Jadhav
Swati Jadhav
Department of Endocrinology, Seth G.S. Medical College and KEM Hospital, Mumbai, Maharashtra, India
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Nilesh Lomte
Nilesh Lomte
Department of Endocrinology, Seth G.S. Medical College and KEM Hospital, Mumbai, Maharashtra, India
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Kunal Thakkar
Kunal Thakkar
Department of Endocrinology, Seth G.S. Medical College and KEM Hospital, Mumbai, Maharashtra, India
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Atul Goel
Atul Goel
Department of Neurosurgery, Seth G.S. Medical College and KEM Hospital, Mumbai, Maharashtra, India
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Abhidha Shah
Abhidha Shah
Department of Neurosurgery, Seth G.S. Medical College and KEM Hospital, Mumbai, Maharashtra, India
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Shilpa Sankhe
Shilpa Sankhe
Department of Radiology, Seth G.S. Medical College and KEM Hospital, Mumbai, Maharashtra, India
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Naina Goel
Naina Goel
Department of Pathology, Seth G.S. Medical College and KEM Hospital, Mumbai, Maharashtra, India
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Neelam Jaguste
Neelam Jaguste
Department of Endocrinology, Seth G.S. Medical College and KEM Hospital, Mumbai, Maharashtra, India
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Tushar Bandgar
Tushar Bandgar
Department of Endocrinology, Seth G.S. Medical College and KEM Hospital, Mumbai, Maharashtra, India
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Nalini Shah
Nalini Shah
Department of Endocrinology, Seth G.S. Medical College and KEM Hospital, Mumbai, Maharashtra, India
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tests have been reported to be positive predictors of sustained remission ( 8 , 9 , 10 ). In the current study, we report long-term follow-up of CD patients after first microscopic TSS. We aim to study the post-operative remission and long
