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Lei Gao Department of Geriatrics, Nanjing Drum Tower Hospital Clinical College of Nanjing Medical University, Nanjing, China

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Wenxia Cui Department of Geriatrics, Nanjing Drum Tower Hospital Clinical College of Nanjing Medical University, Nanjing, China

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Dinghuang Mu Department of Geriatrics, Nanjing Drum Tower Hospital Clinical College of Nanjing University of Chinese Medicine, Nanjing, China

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Shaoping Li Department of Health Management Center, Nanjing Drum Tower Hospital Clinical College of Nanjing Medical University, Nanjing, China

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Nan Li Department of Geriatrics, Nanjing Drum Tower Hospital Clinical College of Nanjing Medical University, Nanjing, China

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Weihong Zhou Department of Health Management Center, Nanjing Drum Tower Hospital Clinical College of Nanjing Medical University, Nanjing, China

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Yun Hu Department of Geriatrics, Nanjing Drum Tower Hospital Clinical College of Nanjing Medical University, Nanjing, China

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models have not been further validated in the MASLD population. Therefore, our aim was to develop a nomogram for the 5-year MASLD risk using data obtained from Chinese health checkup records. We utilized receiver operating characteristic (ROC) curve

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Yujie Ren Endocrine and Diabetes Center, The Affiliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Nanjing, China
Jiangsu Province Academy of Traditional Chinese Medicine, Nanjing, China

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Xue Han Endocrine and Diabetes Center, The Affiliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Nanjing, China
Jiangsu Province Academy of Traditional Chinese Medicine, Nanjing, China

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Yujiang Li Endocrine and Diabetes Center, The Affiliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Nanjing, China
Jiangsu Province Academy of Traditional Chinese Medicine, Nanjing, China

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Guofang Chen Endocrine and Diabetes Center, The Affiliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Nanjing, China
Jiangsu Province Academy of Traditional Chinese Medicine, Nanjing, China
Key Laboratory of TCM Syndrome and Treatment of Yingbing (Thyroid Disease) of State Administration of Traditional Chinese Medicine, Jiangsu Province Academy of Traditional Chinese Medicine, Nanjing, China

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Lin Jiang Department of Endocrinology, The First Affiliated Hospital with Nanjing Medical University, Nanjing, China

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Chao Liu Endocrine and Diabetes Center, The Affiliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Nanjing, China
Jiangsu Province Academy of Traditional Chinese Medicine, Nanjing, China
Key Laboratory of TCM Syndrome and Treatment of Yingbing (Thyroid Disease) of State Administration of Traditional Chinese Medicine, Jiangsu Province Academy of Traditional Chinese Medicine, Nanjing, China

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Shuhang Xu Endocrine and Diabetes Center, The Affiliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Nanjing, China
Jiangsu Province Academy of Traditional Chinese Medicine, Nanjing, China

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are diagnosed as PTMCs ( 5 ). Thyroid cancer is characterized by a favorable prognosis and low tumor-specific mortality ( 6 ). Low-risk PTMC patients usually have an acceptable prognosis, with 10-year and 15-year survivals of 94.6% and 90

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Jakob Kirkegård Department of Clinical Epidemiology, Aarhus University Hospital, Aarhus N, Denmark
Department of Surgery (Section for Upper Gastrointestinal and Hepatico-Pancreatico-Biliary Surgery), Aarhus University Hospital, Aarhus N, Denmark

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Dora Körmendiné Farkas Department of Clinical Epidemiology, Aarhus University Hospital, Aarhus N, Denmark

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Jens Otto Lunde Jørgensen Department of Endocrinology, Aarhus University Hospital, Aarhus N, Denmark

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Deirdre P Cronin-Fenton Department of Clinical Epidemiology, Aarhus University Hospital, Aarhus N, Denmark

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stomach, anal canal, liver, gallbladder and biliary tract and immune related was increased beyond 5 years of follow-up. The risk of rectal cancer was increased within the first year after hypothyroidism diagnosis but was decreased after 5 years (SIR: 0

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Ling-Jun Li Division of O&G, KK Women’s and Children’s Hospital, Singapore, Singapore
O&G ACP, Duke-NUS Graduate Medical School, Singapore, Singapore
Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore

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Izzuddin M Aris Singapore Institute for Clinical Sciences, Agency for Science Technology and Research (A*STAR), Singapore, Singapore

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Lin Lin Su Department of O&G, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore

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Yap Seng Chong Singapore Institute for Clinical Sciences, Agency for Science Technology and Research (A*STAR), Singapore, Singapore
Department of O&G, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore

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Tien Yin Wong O&G ACP, Duke-NUS Graduate Medical School, Singapore, Singapore
Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore

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Kok Hian Tan Division of O&G, KK Women’s and Children’s Hospital, Singapore, Singapore
O&G ACP, Duke-NUS Graduate Medical School, Singapore, Singapore

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Jie Jin Wang O&G ACP, Duke-NUS Graduate Medical School, Singapore, Singapore

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-metabolic diseases. Inclusion criteria are (1) Mothers who attended both baseline and 5-year follow-up visits; (2) Mothers without chronic hypertension and/or diabetes at baseline recruitment and (3) Mothers who were not pregnant at the 5-year follow-up visit

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Peiwen Wu Department of Radiation Oncology, The First Affiliated Hospital of Xi’an Jiaotong University, Xi’an, China

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Dongjie He Department of Radiation Oncology, Tangdu Hospital, the Second Affiliated Hospital of Air Force Medical University, Xi’an, China

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Hao Chang Department of Radiation Oncology, Tangdu Hospital, the Second Affiliated Hospital of Air Force Medical University, Xi’an, China

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Xiaozhi Zhang Department of Radiation Oncology, The First Affiliated Hospital of Xi’an Jiaotong University, Xi’an, China

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those of G4 disease (5-year: AAPC, 0.54; 95% CI, 0.14–0.94; 10-year: AAPC, 0.32; 95% CI, −0.62–1.28). Multivariable analysis of OS Next, we performed a multivariate analysis to further explore the independent prognostic risk factors ( Fig. 6

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Johan Verhelst Department of Endocrinology, ZNA Middelheim Hospital, Antwerp, Belgium

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Anders F Mattsson Pfizer Endocrine Care, Pfizer Health AB, Sollentuna, Sweden

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Cecilia Camacho-Hübner Pfizer Endocrine Care, Pfizer, Inc., New York, New York, USA

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Anton Luger Division of Endocrinology and Metabolism, Medical University and General Hospital, Vienna, Austria

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Roger Abs Antwerp Centre for Endocrinology, Antwerp, Belgium

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prolonged GH replacement The relative risk to develop cardiovascular events according to the presence of MetS at baseline was assessed in 3282 patients: MetS group 6.8 ± 4.7 year of follow-up and NoMS group 7.8 ± 5.1 year of follow-up. Analysis of the

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Victoria Chatzimavridou-Grigoriadou Department of Endocrinology, Christie Hospital NHS Foundation Trust, Manchester, UK
Department of Endocrinology, University of Manchester, School of Medical Sciences, Manchester, UK

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Lisa H Barraclough Department of Endocrinology, Christie Hospital NHS Foundation Trust, Manchester, UK
Department of Endocrinology, University of Manchester, School of Medical Sciences, Manchester, UK

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Rohit Kochhar Department of Clinical Oncology, Christie Hospital NHS Foundation Trust, Manchester, UK

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Lucy Buckley Department of Radiology, Christie Hospital NHS Foundation Trust, Manchester, UK

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Nooreen Alam Department of Radiotherapy, Christie Hospital NHS Foundation Trust, Manchester, UK

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Claire E Higham Department of Endocrinology, University of Manchester, Manchester Academic Health Science Centre, Manchester, UK

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); this participant’s DXA scan revealed a bone density T -score in the lumbar spine of –2.8 and a 10-year risk of 8.8 for hip fracture and 28 for major osteoporotic fracture, falling above the intervention threshold. Figure 1 Number of patients

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David T Broome Department of Endocrinology, Diabetes & Metabolism, Cleveland Clinic Foundation, Cleveland, Ohio, USA

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Gauri B Gadre Department of Internal Medicine, Scripps Clinic, La Jolla, California, USA

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Ehsan Fayazzadeh Department of Radiology, Cleveland Clinic Foundation, Cleveland, Ohio, USA

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James F Bena Department of Quantitative Health Sciences, Cleveland Clinic Foundation, Cleveland, Ohio, USA

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Christian Nasr Department of Endocrinology, Diabetes & Metabolism, Cleveland Clinic Foundation, Cleveland, Ohio, USA

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increase in new cancer diagnoses, this incidence would also increase ( 2 , 3 , 4 ). Survival for low-risk thyroid cancer remains above 90% ( 1 ), and prognosis for patients with metastasis on presentation falls between 23.1 and 31% for 10-year survival

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Yen Kheng Tan Duke-NUS Medical School, SingHealth, Singapore, Singapore

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Yu Heng Kwan Department of Internal Medicine, Singapore General Hospital, Singapore, Singapore

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David Choon Liang Teo Department of Psychological Medicine, Changi General Hospital, Singapore, Singapore

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Marieke Velema Division of Endocrinology, Department of Internal Medicine, Radboud University Medical Centre, Nijmegen, The Netherlands

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Jaap Deinum Division of Vascular Medicine, Department of Internal Medicine, Radboud University Medical Centre, Nijmegen, The Netherlands

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Pei Ting Tan Department of Clinical Trials Research Unit, Changi General Hospital, Singapore, Singapore

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Meifen Zhang Department of Endocrinology, Changi General Hospital, Singapore, Singapore

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Joan Joo Ching Khoo Department of Endocrinology, Changi General Hospital, Singapore, Singapore

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Wann Jia Loh Department of Endocrinology, Changi General Hospital, Singapore, Singapore

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Linsey Gani Department of Endocrinology, Changi General Hospital, Singapore, Singapore

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Thomas F J King Department of Endocrinology, Changi General Hospital, Singapore, Singapore

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Eberta Jun Hui Tan Department of Endocrinology, Changi General Hospital, Singapore, Singapore

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Shui Boon Soh Department of Endocrinology, Changi General Hospital, Singapore, Singapore

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Vanessa Shu Chuan Au Department of Endocrinology, Changi General Hospital, Singapore, Singapore

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Tunn Lin Tay Department of Endocrinology, Changi General Hospital, Singapore, Singapore

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Lily Mae Quevedo Dacay Department of Endocrinology, Changi General Hospital, Singapore, Singapore

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Keng Sin Ng Department of Diagnostic Radiology, Changi General Hospital, Singapore, Singapore

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Kang Min Wong Department of Diagnostic Radiology, Changi General Hospital, Singapore, Singapore

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Andrew Siang Yih Wong Department of Surgery, Changi General Hospital, Singapore, Singapore

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Foo Cheong Ng Department of Urology, Changi General Hospital, Singapore, Singapore

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Tar Choon Aw Department of Laboratory Medicine, Changi General Hospital, Singapore, Singapore

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Yvonne Hui Bin Chan Duke-NUS Medical School, SingHealth, Singapore, Singapore

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Khim Leng Tong Department of Cardiology, Changi General Hospital, Singapore, Singapore

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Sheldon Shao Guang Lee Department of Cardiology, Changi General Hospital, Singapore, Singapore

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Siang Chew Chai Department of Cardiology, Changi General Hospital, Singapore, Singapore

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Troy Hai Kiat Puar Department of Endocrinology, Changi General Hospital, Singapore, Singapore

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, and 1 year post-treatment using two validated questionnaires: RAND 36-Item Health Survey ( 13 ) and the EQ-5D-3L ( 14 ) instrument. Depressive symptoms were assessed with the Beck Depression Inventory-II (BDI-II) ( 15 ). RAND-36 comprises 36 questions

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Elena Izkhakov Institute of Endocrinology, Metabolism and Hypertension, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel
Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
School of Public Health, Faculty of Social Welfare and Health Sciences, University of Haifa, Haifa, Israel

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Joseph Meyerovitch Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
Community Division, Clalit Health Services, Tel Aviv, Israel
The Jesse Z and Sara Lea Shafer Institute for Endocrinology and Diabetes, National Center for Childhood Diabetes, Schneider Children’s Medical Center of Israel, Petah Tikva, Israel

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Micha Barchana School of Public Health, Faculty of Social Welfare and Health Sciences, University of Haifa, Haifa, Israel

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Yacov Shacham Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
Department of Cardiology, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel

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Naftali Stern Institute of Endocrinology, Metabolism and Hypertension, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel
Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel

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Lital Keinan-Boker School of Public Health, Faculty of Social Welfare and Health Sciences, University of Haifa, Haifa, Israel
National Cancer Registry, Israel Center for Disease Control, Ministry of Health, Israel, Ramat Gan, Israel

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exclusion of individuals with a history of CaV&CeV morbidity at study entry. We further demonstrated the cumulative survival curves adjusted to conventional risk factors. A subanalysis compared the 5-year incidence of CV&CeV morbidity following a diagnosis

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