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Nassim Ghaffari-Tabrizi-Wizsy, Christina Angelika Passegger, Laura Nebel, Fabian Krismer, Gudrun Herzer-Schneidhofer, Gert Schwach and Roswitha Pfragner

excised, followed by FFPE-tissue embedding and sectioning. The tumour morphology was analysed by histology and immunostainings. In the EU the CAM assay is not declared as an animal experiment by law and even fulfils the 3R criteria (replacement

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Sofia S Pereira, Mariana P Monteiro, Sonir R Antonini and Duarte Pignatelli

associated with poor overall survival ( 120 ). In the ACC cell line H295R, the restoration of the miR-195 expression led to increased expression of caspase-3, resulting in decreased cell viability. This finding in ACC confirmed the role of miR-195 on

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M A Webb, H Mani, S J Robertson, H L Waller, D R Webb, C L Edwardson, D H Bodicoat, T Yates, K Khunti and M J Davies

RS Balen AH Lobo R Carmina E Chang J Yildiz BO Laven JS , et al . Consensus on women’s health aspects of polycystic ovary syndrome (PCOS): the Amsterdam ESHRE/ASRM-Sponsored 3rd PCOS Consensus Workshop Group . Fertility and Sterility 2012 97

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E R Polina, F M Oliveira, R C Sbruzzi, D Crispim, L H Canani and K G Santos

biochemical pathways that induce inflammation and oxidative stress, thus leading to blood-retinal barrier breakdown, pericyte loss, neuronal death and angiogenesis ( 3 ). miRNAs are small ncRNA molecules that regulate gene expression mainly through the

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Charlotte Janus, Dorte Vistisen, Hanan Amadid, Daniel R Witte, Torsten Lauritzen, Søren Brage, Anne-Louise Bjerregaard, Torben Hansen, Jens J Holst, Marit E Jørgensen, Oluf Pedersen, Kristine Færch and Signe S Torekov

for the subset of participants with cardiorespiratory fitness data available ( n  = 793). Statistical analyses were performed in R, version 3.6.0 (The R Foundation for Statistical Computing) and SAS, version 9.4 (SAS Institute). Descriptive

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Amalie R Lanng, Lærke S Gasbjerg, Natasha C Bergmann, Sigrid Bergmann, Mads M Helsted, Matthew P Gillum, Bolette Hartmann, Jens J Holst, Tina Vilsbøll and Filip K Knop

relation to hypoglycemia – an overview . American Journal of Medicine Studies 2014 46 – 49 . ( https://doi.org/10.12691/ajms-2-3-2 ) 4 Zhao YY Yang R Xiao M Guan MJ Zhao N Zeng T . Kupffer cells activation promoted binge drinking

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Manjeetkaur Sehemby, Prachi Bansal, Vijaya Sarathi, Ashwini Kolhe, Kanchan Kothari, Swati Jadhav-Ramteke, Anurag R Lila, Tushar Bandgar and Nalini S Shah

malignancies of the ovary account for less than 10% of all ovarian cancers (germ cell tumors: 5%; sex cord stromal tumors: 3–5%) ( 1 ). Less than half of these nonepithelial tumors secrete hormones which can produce either estrogenic or androgenic

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G Giuffrida, F Ferraù, R Laudicella, O R Cotta, E Messina, F Granata, F F Angileri, A Vento, A Alibrandi, S Baldari and S Cannavò

2007 60 993 – 1002 ; discussion 1003. ( https://doi.org/10.1227/01.NEU.0000255459.14764.BA ) 10.1227/01.NEU.0000255459.14764.BA 3 Fleseriu M Hashim IA Karavitaki N Melmed S Murad MH Salvatori R Samuels MH . Hormonal replacement in hypopituitarism

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B Shahida, P Sahlstrand Johnson, R Jain, H Brorson, P Åsman, M Lantz and T Planck

pathogenesis of GO ( 3 , 4 ). Almost all patients with Graves’ disease (GD) (98%) already have morphological changes in the retrobulbar space at diagnosis when investigated with CT/MRI, but only 1/3 of the patients will develop clinical ophthalmopathy ( 5

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Thabiso R P Mofokeng, Salem A Beshyah, Fazleh Mahomed, Kwazi C Z Ndlovu and Ian L Ross

Introduction Primary adrenal insufficiency (PAI) is a rare, potentially fatal, but treatable disease ( 1 , 2 ). The estimated prevalence of PAI in South Africa is three per million ( 3 ), in contrast to Western countries in which prevalence