Filter

Refine by collections

Refine by date

—
  • Print
  • Save

Search Results

You are looking at 1 - 10 of 48 items for :

  • 17-hydroxyprogesterone x
Clear All
Muriel Houang Laboratoire des Explorations Fonctionnelles Endocriniennes, Hôpital Armand Trousseau, AP-HP Sorbonne Université, Paris, France

Search for other papers by Muriel Houang in
Google Scholar
PubMed Close
,
Thao Nguyen-Khoa Centre Régional de Dépistage Néonatal-Ile de France, Hôpital Necker-Enfants Malades, AP-HP Centre Université de Paris, Paris, France

Search for other papers by Thao Nguyen-Khoa in
Google Scholar
PubMed Close
,
Thibaut Eguether Sorbonne Université, INSERM, Centre de Recherche Saint-Antoine, Paris, France
Département de Métabolomique Clinique, Hôpital Saint-Antoine, AP-HP Sorbonne Université, Paris, France

Search for other papers by Thibaut Eguether in
Google Scholar
PubMed Close
,
Bettina Ribault Sorbonne Université, INSERM, Centre de Recherche Saint-Antoine, Paris, France
Département de Métabolomique Clinique, Hôpital Saint-Antoine, AP-HP Sorbonne Université, Paris, France

Search for other papers by Bettina Ribault in
Google Scholar
PubMed Close
,
Séverine Brabant Laboratoire d’Explorations Fonctionnelles, Hôpital Necker-Enfants Malades, AP-HP Centre Université de Paris, Paris, France

Search for other papers by Séverine Brabant in
Google Scholar
PubMed Close
,
Michel Polak Centre Régional de Dépistage Néonatal-Ile de France, Hôpital Necker-Enfants Malades, AP-HP Centre Université de Paris, Paris, France
Université de Paris, INSERM, Institut IMAGINE, Hôpital Necker-Enfants Malades, AP-HP, Paris, France

Search for other papers by Michel Polak in
Google Scholar
PubMed Close
,
Irène Netchine Laboratoire des Explorations Fonctionnelles Endocriniennes, Hôpital Armand Trousseau, AP-HP Sorbonne Université, Paris, France
Sorbonne Université, INSERM, Centre de Recherche Saint-Antoine, Paris, France
Hôpital Armand Trousseau, AP-HP Sorbonne Université, Paris, France

Search for other papers by Irène Netchine in
Google Scholar
PubMed Close
, and
Antonin Lamazière Sorbonne Université, INSERM, Centre de Recherche Saint-Antoine, Paris, France
Département de Métabolomique Clinique, Hôpital Saint-Antoine, AP-HP Sorbonne Université, Paris, France

Search for other papers by Antonin Lamazière in
Google Scholar
PubMed Close

critical for boys and girls whose signs of virilization at birth are mild, or that may be missed. The conversion of 17-hydroxyprogesterone (17-OHP) to 11-deoxycortisol and of progesterone to 11-deoxycorticosterone, which are precursors of cortisol and

Article Type:
Research Article
Collections:
Paediatric Endocrinology
DOI:
https://doi.org/10.1530/EC-22-0101
Volume/Issue:
Volume 11: Issue 6
Open access
Ditte Sofie Dahl Sørensen Department of Endocrinology and Metabolism, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark

Search for other papers by Ditte Sofie Dahl Sørensen in
Google Scholar
PubMed Close
,
Jesper Krogh Department of Endocrinology and Metabolism, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark

Search for other papers by Jesper Krogh in
Google Scholar
PubMed Close
,
Åse Krogh Rasmussen Department of Endocrinology and Metabolism, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark

Search for other papers by Åse Krogh Rasmussen in
Google Scholar
PubMed Close
, and
Mikkel Andreassen Department of Endocrinology and Metabolism, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark

Search for other papers by Mikkel Andreassen in
Google Scholar
PubMed Close

focusing on time of day for blood sample collection, phenotype and long-acting vs short-acting glucocorticoid replacement; (iii) to assess concordance between serum levels of 17-hydroxyprogesterone, androstenedione and testosterone in relation to normal

Article Type:
Research Article
Collections:
Adrenal
DOI:
https://doi.org/10.1530/EC-22-0143
Volume/Issue:
Volume 11: Issue 7
Open access
Simone Martins de Castro Hospital Materno Infantil Presidente Vargas, Newborn Screening Referral Center, Porto Alegre, RS, Brazil
Department of Analysis, Universidade Federal do Rio Grande do Sul (UFRGS), School of Pharmacy, Porto Alegre, RS, Brazil

Search for other papers by Simone Martins de Castro in
Google Scholar
PubMed Close
,
Paloma Wiest Universidade Federal de Ciências da Saúde de Porto Alegre (UFCSPA), Porto Alegre, RS, Brazil

Search for other papers by Paloma Wiest in
Google Scholar
PubMed Close
,
Poli Mara Spritzer Division of Endocrinology, Department of Physiology, Universidade Federal do Rio Grande do Sul (UFRGS), Hospital de Clínicas de Porto Alegre (HCPA), Porto Alegre, RS, Brazil

Search for other papers by Poli Mara Spritzer in
Google Scholar
PubMed Close
, and
Cristiane Kopacek Hospital Materno Infantil Presidente Vargas, Newborn Screening Referral Center, Porto Alegre, RS, Brazil
Universidade Federal de Ciências da Saúde de Porto Alegre (UFCSPA), Porto Alegre, RS, Brazil
Department of Pediatrics, Universidade Federal do Rio Grande do Sul (UFRGS), Medical School, Porto Alegre, RS, Brazil

Search for other papers by Cristiane Kopacek in
Google Scholar
PubMed Close

progesterone to 11-deoxycorticosterone and 17-hydroxyprogesterone (17-OHP) to 11-deoxycortisol, decreasing mineralocorticoid and glucocorticoid levels and increasing progesterone and 17-OHP levels ( 5 , 6 ). Clinically, CAH is divided into classical and

Article Type:
Research Article
Collections:
Adrenal
DOI:
https://doi.org/10.1530/EC-23-0162
Volume/Issue:
Volume 12: Issue 12
Open access
Sandra R Dahl Hormone Laboratory, Department of Medical Biochemistry, Oslo University Hospital, Oslo, Norway

Search for other papers by Sandra R Dahl in
Google Scholar
PubMed Close
,
Ingrid Nermoen Institute of Clinical Medicine, University of Oslo, Oslo, Norway
Division of Medicine, Akershus University Hospital, Lørenskog, Norway

Search for other papers by Ingrid Nermoen in
Google Scholar
PubMed Close
,
Ingeborg Brønstad National Centre for Ultrasound in Gastroenterology, Haukeland University Hospital, Bergen, Norway
Department of Clinical Medicine, University of Bergen, Bergen, Norway

Search for other papers by Ingeborg Brønstad in
Google Scholar
PubMed Close
,
Eystein S Husebye Department of Clinical Science, University of Bergen, Bergen, Norway
K.G. Jebsen-Center for Autoimmune Diseases, University of Bergen, Bergen, Norway
Department of Medicine, Haukeland University Hospital, Bergen, Norway

Search for other papers by Eystein S Husebye in
Google Scholar
PubMed Close
,
Kristian Løvås Department of Clinical Science, University of Bergen, Bergen, Norway
K.G. Jebsen-Center for Autoimmune Diseases, University of Bergen, Bergen, Norway
Department of Medicine, Haukeland University Hospital, Bergen, Norway

Search for other papers by Kristian Løvås in
Google Scholar
PubMed Close
, and
Per M Thorsby Hormone Laboratory, Department of Medical Biochemistry, Oslo University Hospital, Oslo, Norway

Search for other papers by Per M Thorsby in
Google Scholar
PubMed Close

assessment is not sensitive enough to identify subtle over- and under-treatment. Assay of the intermediates 17-hydroxyprogesterone (17OHP) and androstenedione is often used, but results are often difficult to interpret as cross-reactivity between steroids

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-18-0453
Volume/Issue:
Volume 7: Issue 12
Open access
Johanna Christina Penell Department of Clinical Sciences, Swedish University of Agricultural Sciences, Uppsala, Sweden
Department of Medical Sciences, Occupational and Environmental Medicine, Uppsala University, Uppsala, Sweden

Search for other papers by Johanna Christina Penell in
Google Scholar
PubMed Close
,
Mark M Kushnir Department of Pathology, University of Utah School of Medicine, Salt Lake City, Utah, USA
ARUP Institute for Clinical and Experimental Pathology, Salt Lake City, Utah, USA

Search for other papers by Mark M Kushnir in
Google Scholar
PubMed Close
,
Lars Lind Department of Medical Sciences, Cardiovascular Epidemiology, Uppsala University, Uppsala, Sweden

Search for other papers by Lars Lind in
Google Scholar
PubMed Close
,
Jonatan Bergquist Department of Chemistry – BMC, Analytical Chemistry, Uppsala University, Uppsala, Sweden

Search for other papers by Jonatan Bergquist in
Google Scholar
PubMed Close
,
Jonas Bergquist Department of Pathology, University of Utah School of Medicine, Salt Lake City, Utah, USA
Department of Chemistry – BMC, Analytical Chemistry, Uppsala University, Uppsala, Sweden

Search for other papers by Jonas Bergquist in
Google Scholar
PubMed Close
,
P Monica Lind Department of Medical Sciences, Occupational and Environmental Medicine, Uppsala University, Uppsala, Sweden

Search for other papers by P Monica Lind in
Google Scholar
PubMed Close
, and
Tord Naessen Department of Women’s and Children’s Health, Uppsala University, Uppsala, Sweden

Search for other papers by Tord Naessen in
Google Scholar
PubMed Close

informed consent form, and the study was approved by the human ethics committee of Uppsala University, Sweden. Reagents and standards Testosterone, estrone, estradiol, pregnenolone, 17-hydroxypregnenolone, 17-hydroxyprogesterone, 11-deoxycortisol

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-21-0045
Volume/Issue:
Volume 10: Issue 5
Open access
Dafydd Aled Rees Cardiff University, Cardiff, United Kingdom

Search for other papers by Dafydd Aled Rees in
Google Scholar
PubMed Close
,
Deborah P Merke National Institutes of Health Clinical Center and the Eunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, USA

Search for other papers by Deborah P Merke in
Google Scholar
PubMed Close
,
Wiebke Arlt MRC LMS, London, United Kingdom

Search for other papers by Wiebke Arlt in
Google Scholar
PubMed Close
,
Aude Brac De La Perriere Hospices Civils de Lyon - GHE - Endocrinologie, Bron, France

Search for other papers by Aude Brac De La Perriere in
Google Scholar
PubMed Close
,
Angelica Linden Hirschberg Karolinska Institute, Solna, Sweden

Search for other papers by Angelica Linden Hirschberg in
Google Scholar
PubMed Close
,
Anders Juul Department of Growth and Reproduction, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark, and Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark

Search for other papers by Anders Juul in
Google Scholar
PubMed Close
,
John Newell-Price The University of Sheffield, Sheffield, United Kingdom

Search for other papers by John Newell-Price in
Google Scholar
PubMed Close
,
Alessandro Prete University of Birmingham, Birmingham, United Kingdom

Search for other papers by Alessandro Prete in
Google Scholar
PubMed Close
,
Nicole Reisch Endokrinologie, Nephrologie und weitere Sektionen - Medizinische Klinik und Poliklinik IV - Campus Innenstadt, München, Germany

Search for other papers by Nicole Reisch in
Google Scholar
PubMed Close
,
Nike M Stikkelbroeck Radboud University Nijmegen, Nijmegen, Netherlands

Search for other papers by Nike M Stikkelbroeck in
Google Scholar
PubMed Close
,
Philippe A Touraine University Hospitals Pitié Salpêtrière - Charles Foix, Paris, France

Search for other papers by Philippe A Touraine in
Google Scholar
PubMed Close
,
Alex Lewis Neurocrine Biosciences Inc, London, United Kingdom

Search for other papers by Alex Lewis in
Google Scholar
PubMed Close
,
John Porter Neurocrine Biosciences Inc, London, United Kingdom

Search for other papers by John Porter in
Google Scholar
PubMed Close
,
Helen Coope Neurocrine Biosciences Inc, London, United Kingdom

Search for other papers by Helen Coope in
Google Scholar
PubMed Close
, and
Richard J Ross The University of Sheffield, Sheffield, United Kingdom

Search for other papers by Richard J Ross in
Google Scholar
PubMed Close

half-life after oral administration than hydrocortisone: 2.1 to 3.5 h vs ~1.5 h ( 7 , 8 ); however, detailed studies of pharmacokinetics and disease control in CAH show that prednisolone levels fall by the morning and ACTH and 17-hydroxyprogesterone

Article Type:
Research Article
Collections:
Adrenal
DOI:
https://doi.org/10.1530/EC-24-0150
Volume/Issue:
Volume 13: Issue 8
Open access
Fidéline Bonnet-Serrano Université Paris Cité, Paris, France
Inserm U1016-CNRS UMR8104, Paris, France
Hormonology Department, Cochin Hospital, Paris, France

Search for other papers by Fidéline Bonnet-Serrano in
Google Scholar
PubMed Close
,
Maxime Barat Université Paris Cité, Paris, France
Inserm U1016-CNRS UMR8104, Paris, France
Radiology Department, Cochin Hospital, Paris, France

Search for other papers by Maxime Barat in
Google Scholar
PubMed Close
,
Anna Vaczlavik Université Paris Cité, Paris, France
Inserm U1016-CNRS UMR8104, Paris, France
Reference Center for Rare Adrenal Diseases, Endocrinology Department, Cochin Hospital, Paris, France

Search for other papers by Anna Vaczlavik in
Google Scholar
PubMed Close
,
Anne Jouinot Inserm U1016-CNRS UMR8104, Paris, France

Search for other papers by Anne Jouinot in
Google Scholar
PubMed Close
,
Lucas Bouys Université Paris Cité, Paris, France
Inserm U1016-CNRS UMR8104, Paris, France
Reference Center for Rare Adrenal Diseases, Endocrinology Department, Cochin Hospital, Paris, France

Search for other papers by Lucas Bouys in
Google Scholar
PubMed Close
,
Christelle Laguillier-Morizot Université Paris Cité, Paris, France
Hormonology Department, Cochin Hospital, Paris, France
INSERM, Physiopathologie et Pharmacotoxicologie Placentaire Humaine : Microbiote Pré & Post natal, Paris, France

Search for other papers by Christelle Laguillier-Morizot in
Google Scholar
PubMed Close
,
Corinne Zientek Hormonology Department, Cochin Hospital, Paris, France

Search for other papers by Corinne Zientek in
Google Scholar
PubMed Close
,
Catherine Simonneau Hormonology Department, Cochin Hospital, Paris, France

Search for other papers by Catherine Simonneau in
Google Scholar
PubMed Close
,
Etienne Larger Université Paris Cité, Paris, France
Inserm U1016-CNRS UMR8104, Paris, France
Diabetology Department, Cochin Hospital, Paris, France

Search for other papers by Etienne Larger in
Google Scholar
PubMed Close
,
Laurence Guignat Reference Center for Rare Adrenal Diseases, Endocrinology Department, Cochin Hospital, Paris, France

Search for other papers by Laurence Guignat in
Google Scholar
PubMed Close
,
Lionel Groussin Université Paris Cité, Paris, France
Inserm U1016-CNRS UMR8104, Paris, France
Reference Center for Rare Adrenal Diseases, Endocrinology Department, Cochin Hospital, Paris, France

Search for other papers by Lionel Groussin in
Google Scholar
PubMed Close
,
Guillaume Assié Université Paris Cité, Paris, France
Inserm U1016-CNRS UMR8104, Paris, France
Reference Center for Rare Adrenal Diseases, Endocrinology Department, Cochin Hospital, Paris, France

Search for other papers by Guillaume Assié in
Google Scholar
PubMed Close
,
Jean Guibourdenche Université Paris Cité, Paris, France
Hormonology Department, Cochin Hospital, Paris, France
INSERM, Physiopathologie et Pharmacotoxicologie Placentaire Humaine : Microbiote Pré & Post natal, Paris, France

Search for other papers by Jean Guibourdenche in
Google Scholar
PubMed Close
,
Ioannis Nicolis Université Paris Cité, Paris, France
UR 7537 BioSTM, Paris, France

Search for other papers by Ioannis Nicolis in
Google Scholar
PubMed Close
,
Marie-Claude Menet Institut de Chimie Physique, Université Paris-Saclay-CNRS, UMR8000, Orsay, France

Search for other papers by Marie-Claude Menet in
Google Scholar
PubMed Close
, and
Jérôme Bertherat Université Paris Cité, Paris, France
Inserm U1016-CNRS UMR8104, Paris, France
Reference Center for Rare Adrenal Diseases, Endocrinology Department, Cochin Hospital, Paris, France

Search for other papers by Jérôme Bertherat in
Google Scholar
PubMed Close

precursor, located upstream of the deficient enzyme. In this context, CYP21A2 enzyme is the most frequently affected in patients with congenital adrenal hyperplasia (CAH), leading to an excessive response of 17-hydroxyprogesterone (17OHP) to ACTH1-24. In

Article Type:
Research Article
Collections:
Adrenal
DOI:
https://doi.org/10.1530/EC-22-0063
Volume/Issue:
Volume 11: Issue 8
Open access
Timothy J Morris Directorate of Biochemistry, Manchester University NHS Foundation Trust, Manchester, UK
Faculty of Biology Medicine and Health, University of Manchester, Manchester, UK

Search for other papers by Timothy J Morris in
Google Scholar
PubMed Close
,
Andrew Whatmore Division of Developmental Biology and Medicine, University of Manchester, Royal Manchester Children’s Hospital, Manchester, UK

Search for other papers by Andrew Whatmore in
Google Scholar
PubMed Close
,
Laura Hamilton Pathology Department, Clinical Biochemistry, Huddersfield Royal Infirmary, Lindley, Huddersfield, UK

Search for other papers by Laura Hamilton in
Google Scholar
PubMed Close
,
Beverly Hird Directorate of Biochemistry, Manchester University NHS Foundation Trust, Manchester, UK

Search for other papers by Beverly Hird in
Google Scholar
PubMed Close
,
Eric S Kilpatrick Directorate of Biochemistry, Manchester University NHS Foundation Trust, Manchester, UK

Search for other papers by Eric S Kilpatrick in
Google Scholar
PubMed Close
,
Lesley Tetlow Directorate of Biochemistry, Manchester University NHS Foundation Trust, Manchester, UK

Search for other papers by Lesley Tetlow in
Google Scholar
PubMed Close
, and
Peter Clayton Division of Developmental Biology and Medicine, University of Manchester, Royal Manchester Children’s Hospital, Manchester, UK

Search for other papers by Peter Clayton in
Google Scholar
PubMed Close

treatment with fludrocortisone, using sodium, potassium, renin and 17α-hydroxyprogesterone (17α-OHP) levels as markers ( 2 ). Materials and methods The service review was carried out on patients with salt-wasting adrenal insufficiency, the majority

Article Type:
Research Article
Collections:
Adrenal
DOI:
https://doi.org/10.1530/EC-23-0370
Volume/Issue:
Volume 13: Issue 2
Open access
T P Parikh Program in Reproductive and Adult Endocrinology, National Institute of Child Health and Human Development, National Institutes of Health (NIH), Bethesda, Maryland, USA

Search for other papers by T P Parikh in
Google Scholar
PubMed Close
,
B Stolze Department of Laboratory Medicine, Clinical Center, NIH, Bethesda, Maryland, USA

Search for other papers by B Stolze in
Google Scholar
PubMed Close
,
Y Ozarda Department of Medical Biochemistry, Faculty of Medicine, Uludag University, Bursa, Turkey

Search for other papers by Y Ozarda in
Google Scholar
PubMed Close
,
J Jonklaas Division of Endocrinology and Metabolism, Department of Medicine, Georgetown University, Washington, District of Columbia, USA

Search for other papers by J Jonklaas in
Google Scholar
PubMed Close
,
K Welsh Department of Laboratory Medicine, Clinical Center, NIH, Bethesda, Maryland, USA

Search for other papers by K Welsh in
Google Scholar
PubMed Close
,
L Masika Department of Laboratory Medicine and Pathology/National Health Laboratory Service Walter Sisulu University, Mthatha, South Africa

Search for other papers by L Masika in
Google Scholar
PubMed Close
,
M Hill Program in Reproductive and Adult Endocrinology, National Institute of Child Health and Human Development, National Institutes of Health (NIH), Bethesda, Maryland, USA

Search for other papers by M Hill in
Google Scholar
PubMed Close
,
A DeCherney Program in Reproductive and Adult Endocrinology, National Institute of Child Health and Human Development, National Institutes of Health (NIH), Bethesda, Maryland, USA

Search for other papers by A DeCherney in
Google Scholar
PubMed Close
, and
S J Soldin Department of Laboratory Medicine, Clinical Center, NIH, Bethesda, Maryland, USA
Division of Endocrinology and Metabolism, Department of Medicine, Georgetown University, Washington, District of Columbia, USA

Search for other papers by S J Soldin in
Google Scholar
PubMed Close

nine steroid hormones (cortisone, cortisol, corticosterone, 11 deoxycortisol, androstenedione, testosterone, 17a-hydroxyprogesterone, DHEA and progesterone) was performed using our previously published micro HPLC–MS/MS methods ( 6 , 7 ). Diagnostic

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-18-0417
Volume/Issue:
Volume 7: Issue 12
Open access
Paul-Martin Holterhus Department of Pediatrics I, Pediatric Endocrinology and Diabetology, University Hospital of Schleswig-Holstein, UKSH, Campus Kiel and Christian Albrechts University, CAU, Kiel, Germany

Search for other papers by Paul-Martin Holterhus in
Google Scholar
PubMed Close
,
Alexandra Kulle Department of Pediatrics I, Pediatric Endocrinology and Diabetology, University Hospital of Schleswig-Holstein, UKSH, Campus Kiel and Christian Albrechts University, CAU, Kiel, Germany

Search for other papers by Alexandra Kulle in
Google Scholar
PubMed Close
,
Anne-Marie Till Department of Pediatrics, Pediatric Hematology and Oncology, University Hospital of Schleswig-Holstein, UKSH, Campus Lübeck, Germany

Search for other papers by Anne-Marie Till in
Google Scholar
PubMed Close
,
Caroline Stille Department of Pediatrics, Pediatric Hematology and Oncology, University Hospital of Schleswig-Holstein, UKSH, Campus Lübeck, Germany

Search for other papers by Caroline Stille in
Google Scholar
PubMed Close
,
Tabea Lamprecht Department of Pediatrics I, Pediatric Endocrinology and Diabetology, University Hospital of Schleswig-Holstein, UKSH, Campus Kiel and Christian Albrechts University, CAU, Kiel, Germany

Search for other papers by Tabea Lamprecht in
Google Scholar
PubMed Close
,
Simon Vieth Department of Pediatrics I, Pediatric Hematology and Oncology, University Hospital of Schleswig-Holstein, UKSH, Campus Kiel and Christian-Albrechts-University, CAU, Kiel, Germany

Search for other papers by Simon Vieth in
Google Scholar
PubMed Close
, and
Melchior Lauten Department of Pediatrics, Pediatric Hematology and Oncology, University Hospital of Schleswig-Holstein, UKSH, Campus Lübeck, Germany

Search for other papers by Melchior Lauten in
Google Scholar
PubMed Close

glucocorticoid synthesis, namely 17-hydroxyprogesterone (17OHP), 11-deoxycortisol and cortisol as well as three steroids representing mineralocorticoid synthesis namely 11-deoxycorticosterone (DOC), corticosterone and aldosterone were measured in a parallel assay

Article Type:
Research Article
Collections:
Adrenal
DOI:
https://doi.org/10.1530/EC-23-0002
Volume/Issue:
Volume 12: Issue 10
Open access