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Manjeetkaur Sehemby, Prachi Bansal, Vijaya Sarathi, Ashwini Kolhe, Kanchan Kothari, Swati Jadhav-Ramteke, Anurag R Lila, Tushar Bandgar and Nalini S Shah

presentation. Case records of the patients fulfilling the inclusion criteria were reviewed and patient information including age of presentation, onset and duration of symptoms, clinical features (menstrual abnormalities, hirsutism and signs of virilisation

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Agnieszka Pazderska, Yaasir Mamoojee, Satish Artham, Margaret Miller, Stephen G Ball, Tim Cheetham and Richard Quinton

regime has been significantly informed by our parallel clinical experience in achieving virilisation of testosterone-naïve (natal female) transgender males. Patients and methods Case records were reviewed for all CHH men ( n  = 7) who have been

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R Walia, M Singla, K Vaiphei, S Kumar and A Bhansali

for hypospadias and orchidopexy were performed and testosterone supplementation was started to enhance virilisation in patients with male sex of rearing. Patients with female sex of rearing underwent gonadectomy followed by oestrogen replacement

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Martin Zweifel, Beat Thürlimann, Salome Riniker, Patrik Weder, Roger von Moos, Olivia Pagani, Martin Bigler, Karin M Rothgiesser, Christiane Pilop, Hanne Hawle, Peter Brauchli, Coya Tapia, Wolfgang Schoenfeld, Cristiana Sessa and for the Swiss Group for Clinical Cancer Research (SAKK)

). Side effects such as hirsutism and other signs of virilisation in treated women and the evidence that testosterone may be easily converted to estrogens in the body led to the discontinuation of its use ( 5 ). These findings suggest that selective

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Jennifer K Y Ko, Thomas F J King, Louise Williams, Sarah M Creighton and Gerard S Conway

hydroxysteroid 17-beta dehydrogenase 3 (HSD17B3) can mimic CAIS on occasion. If an individual has not had sufficient exposure to endogenous testosterone, then we favour starting testosterone at low dose for several months. Some features of virilisation such as

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Bruno Donadille, Muriel Houang, Irène Netchine, Jean-Pierre Siffroi and Sophie Christin-Maitre

HSD3B2 gene mutations (ORPHA90791) is an extremely rare form of congenital adrenal hyperplasia disease. In the severe form, the phenotype leads to neonatal salt wasting and severe male virilisation deficit. Our study illustrates the fact that

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Elin Kahlert, Martina Blaschke, Knut Brockmann, Clemens Freiberg, Onno E Janssen, Nikolaus Stahnke, Domenika Strik, Martin Merkel, Alexander Mann, Klaus-Peter Liesenkötter and Heide Siggelkow

study . Journal of Clinical Endocrinology and Metabolism 2000 3199 – 3202 . ( ) 40 Page DC . Y chromosome sequences in Turner’s syndrome and risk of gonadoblastoma or virilisation . Lancet 1994 240

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André Marques-Pinto and Davide Carvalho

ED during the virilisation period (around 8–14 weeks into human foetal development) will perhaps cause TDS (138) . Moreover, disproportionate oestrogenic exposure at this point may disturb the delicate androgen–oestrogen balance, leading to adverse

Open access

L A Hughes, K McKay-Bounford, E A Webb, P Dasani, S Clokie, H Chandran, L McCarthy, Z Mohamed, J M W Kirk, N P Krone, S Allen and T R P Cole

of virilisation in patients due to the presence of wildtype androgen receptor ( 19 ). Distinguishing mosaic from non-mosaic forms therefore can have significant consequences for patient management and genetic recurrence risk. Identifying the correct