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Yueyuan Yang Department of Endocrinology, Renmin Hospital of Wuhan University, Wuhan, China

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Tingting Yu Department of Radiology, Renmin Hospital of Wuhan University, Wuhan, China

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Zhili Niu Department of Clinical Laboratory, Institute of translational medicine, Renmin Hospital of Wuhan University, Wuhan, China

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Ling Gao Department of Endocrinology, Renmin Hospital of Wuhan University, Wuhan, China

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general population ( 5 , 6 ). Therefore, investigating predictive markers for atherosclerosis holds clinical significance for the secondary prevention of stroke in patients with T2D. Uridine is a natural nucleoside involved in substance synthesis and

Article Type:
Research Article
Collections:
Metabolic Syndrome and Diabetes
DOI:
https://doi.org/10.1530/EC-24-0075
Volume/Issue:
Volume 13: Issue 6
Open access
Annette Mouritsen Department of Growth and Reproduction, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
International Center for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, University of Copenhagen, Copenhagen, Denmark

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Alexander Siegfried Busch Department of Growth and Reproduction, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
International Center for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, University of Copenhagen, Copenhagen, Denmark

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Lise Aksglaede Department of Growth and Reproduction, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
International Center for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, University of Copenhagen, Copenhagen, Denmark

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Ewa Rajpert-De Meyts Department of Growth and Reproduction, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
International Center for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, University of Copenhagen, Copenhagen, Denmark

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Anders Juul Department of Growth and Reproduction, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
International Center for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, University of Copenhagen, Copenhagen, Denmark

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urine depends on sulfation and glucuronidation of steroids to water-soluble conjugates. One of the several essential glucuronidases is uridine diphosphate glucuronyltransferase 2B17, encoded by the UGT2B17 gene, and several studies observed a lower

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-18-0080
Volume/Issue:
Volume 7: Issue 3
Open access
Run-Qing Xiong Department of Ultrasonic Imaging, Xiamen Medical College Affiliated Second Hospital, Fujian, China

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Yan-Ping Li Key Laboratory of Functional and Clinical Translational Medicine, Fujian Province University, Xiamen Medical College, Fujian, China

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Lu-Ping Lin Department of Endocrinology, Xiamen Medical College Affiliated Second Hospital, Fujian, China

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Jeng-Yuan Yao Key Laboratory of Functional and Clinical Translational Medicine, Fujian Province University, Xiamen Medical College, Fujian, China

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-phosphate, saccharopine, uridine diphosphate glucose, 11-ketoetiocholanolone, inosinic acid, 3-methylcrotonylglycine, aldosterone, and docosapentaenoic acid ( Table 2 ). Table 2 Metabolites with significant abundance changes in DCM group. This table

Article Type:
Research Article
Collections:
Cardiovascular
DOI:
https://doi.org/10.1530/EC-23-0384
Volume/Issue:
Volume 13: Issue 3
Open access
Charlotte Höybye Department of Endocrinology, Department of Molecular Medicine and Surgery, Metabolism and Diabetology, Karolinska University Hospital, 171 76 Stockholm, Sweden
Department of Endocrinology, Department of Molecular Medicine and Surgery, Metabolism and Diabetology, Karolinska University Hospital, 171 76 Stockholm, Sweden

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Erik Wahlström Department of Endocrinology, Department of Molecular Medicine and Surgery, Metabolism and Diabetology, Karolinska University Hospital, 171 76 Stockholm, Sweden

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Petra Tollet-Egnell Department of Endocrinology, Department of Molecular Medicine and Surgery, Metabolism and Diabetology, Karolinska University Hospital, 171 76 Stockholm, Sweden

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Gunnar Norstedt Department of Endocrinology, Department of Molecular Medicine and Surgery, Metabolism and Diabetology, Karolinska University Hospital, 171 76 Stockholm, Sweden

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, cystine and palmitoleic acid were found to be decreased in GHD patients, whereas glutamic acid, aspartic acid, hypoxanthine-like, uridine and glyceric acid were increased. A marked difference was observed in glyceric acid and glutamic acid. GH treatment

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-14-0098
Volume/Issue:
Volume 3: Issue 4
Open access
Nandini Shankara Narayana Andrology Department, Concord Hospital and, ANZAC Research Institute, University of Sydney, Sydney, Australia

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Lam P Ly Andrology Department, Concord Hospital and, ANZAC Research Institute, University of Sydney, Sydney, Australia

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Veena Jayadev Andrology Department, Concord Hospital and, ANZAC Research Institute, University of Sydney, Sydney, Australia

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Carolyn Fennell Andrology Department, Concord Hospital and, ANZAC Research Institute, University of Sydney, Sydney, Australia

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Sasha Savkovic Andrology Department, Concord Hospital and, ANZAC Research Institute, University of Sydney, Sydney, Australia

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Ann J Conway Andrology Department, Concord Hospital and, ANZAC Research Institute, University of Sydney, Sydney, Australia

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David J Handelsman Andrology Department, Concord Hospital and, ANZAC Research Institute, University of Sydney, Sydney, Australia

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. Other variables that might influence inter-injection interval but not measured in this study include functional genetic variants of androgen metabolism. These include the androgen receptor (AR) CAG triplet repeat polymorphism ( 32 ) and the uridine

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-21-0109
Volume/Issue:
Volume 10: Issue 7
Open access
Jintao Hu Department of Neurosurgery, Xinqiao Hospital, The Army Medical University, Chongqing, China

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Qingbo Chen Department of Neurosurgery, Xinqiao Hospital, The Army Medical University, Chongqing, China

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Xiao Ding Department of Neurosurgery, Xinqiao Hospital, The Army Medical University, Chongqing, China

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Xin Zheng Department of Neurosurgery, Xinqiao Hospital, The Army Medical University, Chongqing, China

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Xuefeng Tang Department of Pathology, Xinqiao Hospital, The Army Medical University, Chongqing, China

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Song Li Department of Neurosurgery, Xinqiao Hospital, The Army Medical University, Chongqing, China

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Hui Yang Department of Neurosurgery, Xinqiao Hospital, The Army Medical University, Chongqing, China

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blockage of the nucleotide de novo synthesis pathway. Conversely, we observed a significant increase in the intracellular levels of inosine, guanosine, cytidine, and uridine (Supplementary Fig. 2), indicating a blockage of the nucleotide salvage pathway

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-19-0515
Volume/Issue:
Volume 9: Issue 3
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Bilal B Mughal CNRS/UMR7221, Muséum National d’Histoire Naturelle, Sorbonne Universités, Paris, France

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Jean-Baptiste Fini CNRS/UMR7221, Muséum National d’Histoire Naturelle, Sorbonne Universités, Paris, France

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Barbara A Demeneix CNRS/UMR7221, Muséum National d’Histoire Naturelle, Sorbonne Universités, Paris, France

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fungicide can enhance TH hepatic metabolism through the induction of enzymes uridine diphosphate-glucuronosyl-transferase (UDPGT), thereby increasing biliary elimination of T 3 and T 4 ( 249 ). Reduction of TH level varies considerably depending on the

Article Type:
Review Article
DOI:
https://doi.org/10.1530/EC-18-0029
Volume/Issue:
Volume 7: Issue 4
Open access