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Philippe Thuillier, Nathalie Roudaut, Geneviève Crouzeix, Marie Cavarec, Philippe Robin, Ronan Abgral, Véronique Kerlan and Pierre-Yves Salaun

carotid duplex ultrasonography varies from 9.4% to 27.0% ( 1 ). In cervical computed tomography (CT) and magnetic resonance imaging (MRI) scans, studies show a prevalence of TI nearly to 16% ( 2 , 3 ). The common use of 18F-fluorodeoxyglucose (FDG

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Kristine Zøylner Swan, Steen Joop Bonnema, Marie Louise Jespersen and Viveque Egsgaard Nielsen

ultrasonography (US) and fine-needle aspiration biopsy (FNAB) are very useful in the evaluation of thyroid nodules, the identification of malignancy remains a challenge. Several US characteristics have been found to be more prevalent in malignant compared with

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Bekir Cakir, F Neslihan Cuhaci Seyrek, Oya Topaloglu, Didem Ozdemir, Ahmet Dirikoc, Cevdet Aydin, Sefika Burcak Polat, Berna Evranos Ogmen, Ali Abbas Tam, Husniye Baser, Aylin Kilic Yazgan, Mehmet Kilic, Afra Alkan and Reyhan Ersoy

unilateral MIP ( 2 ). Given that MIP has become the preferred approach in many centres, preoperative localisation of PAs has also become essential ( 7 ). Preoperative localisation of PAs has been primarily achieved through ultrasonography (US) and

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Aasem Saif, Shrook Mousa, Maha Assem, Nashwa Tharwat and Alaa Abdelhamid

CIMT was performed using high-resolution color-coded Doppler ultrasonography (ALT HDI, Ultramark) using a 12-MHz linear array. Patients and control subjects were examined in the supine position, with the head turned 45° from the side during scanning

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Klaudia Zajkowska, Janusz Kopczyński, Stanisław Góźdź and Aldona Kowalska

more frequent in IFVPTC than in NIFTP ( 51 , 82 ). However, studies suggest that ultrasonography is insufficient for differentiating NIFTP from invasive EFVPTC ( 80 , 81 , 83 ). Both tumours show a similar appearance in cytological examinations as

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Manjeetkaur Sehemby, Prachi Bansal, Vijaya Sarathi, Ashwini Kolhe, Kanchan Kothari, Swati Jadhav-Ramteke, Anurag R Lila, Tushar Bandgar and Nalini S Shah

reproductive age women but were low-normal in postmenopausal ones. As shown in Table 2 , transabdominal ultrasonography (TAS) was the initial investigation in all patients suspected VOT. It detected lesions in all except two. Case no 3 had no evidence of

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Luigia Cinque, Angelo Sparaneo, Antonio S Salcuni, Danilo de Martino, Claudia Battista, Francesco Logoluso, Orazio Palumbo, Roberto Cocchi, Evaristo Maiello, Paolo Graziano, Geoffrey N Hendy, David E C Cole, Alfredo Scillitani and Vito Guarnieri

at neck ultrasonography and confirmed by 99mTc-Sestamibi scan, but are yet to be excised. Biochemical evaluation of other relatives, one brother and sister, and paternal nephew ( Fig. 1A : II-1, II-3, and III-2) was negative. Figure 1 Pedigree

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Giorgio Grani, Livia Lamartina, Vito Cantisani, Marianna Maranghi, Piernatale Lucia and Cosimo Durante

role the differential diagnosis, but its execution needs to be selective ( 2 ), due to the associated costs, potential non-diagnostic results ( 3 ), and the risk of overdiagnosis ( 4 ). Ultrasonography (US) is currently the best diagnostic tool

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Verônica Carneiro Borges Mioto, Ana Carolina de Castro Nassif Gomes Monteiro, Rosalinda Yossie Asato de Camargo, Andréia Rodrigues Borel, Regina Maria Catarino, Sergio Kobayashi, Maria Cristina Chammas and Suemi Marui

–Kolthoff reaction was used to determine the UIC, and all samples were measured in duplicate ( 13 ). Thyroid ultrasonography A thyroid ultrasound was performed on each pregnant woman by the same physician (Ana Carolina de Castro Nassif Gomes Monteiro) using a

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Marco Marino, Valentina Cirello, Valentina Gnarini, Carla Colombo, Elisa Pignatti, Livio Casarini, Chiara Diazzi, Vincenzo Rochira, Katia Cioni, Bruno Madeo, Cesare Carani, Manuela Simoni and Laura Fugazzola

Papillary thyroid carcinoma (PTC) is the most common endocrine malignancy, with a steadily increasing incidence in the last few decades worldwide. The predisposition to developing this carcinoma by the heterozygous state of rs2910164 within the precursor of the miR-146a has been reported, but recently not confirmed. Interestingly, on the same chromosome, almost 50 kb separate the pre-miR-146a from the pituitary tumor-transforming gene 1 (PTTG1), a proto-oncogene involved in several tumors, including thyroid cancers. In this study, we analyzed, using a case–control design, the genetic association between PTC and the genomic region encompassing pre-miR-146a rs2910164 and PTTG1 rs1862391 and rs2910202. We enrolled 307 affected patients and 206 healthy controls. The possible presence of thyroid nodules in controls was excluded by ultrasonography. All the cases were submitted to single-nucleotide polymorphism (SNP) genotyping of pre-miR-146a and PTTG1, and risk association analyses were carried out. The genotypic and allelic frequencies of pre-miR-146a rs2910164 were not statistically different in the patients and controls, and this SNP was not in linkage disequilibrium with the investigated PTTG1 SNPs. Consistently, meta-analyses, the first including all the affected cases published to date, did not confirm the previously reported association of the heterozygous CG genotype with PTC. The PTTG1 SNPs exhibited the same allelic frequency in the patients and controls and were not associated with the disease. In conclusion, in a well-selected Italian population, neither pre-miR-146a rs2910164 nor PTTG1 rs1862391 and rs2910202 were found to be associated with the risk of developing PTC.