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Ali Abbasi

Introduction Over the past decade, interest in studying biological markers (biomarkers) for type 2 diabetes (T2D) has increased intensely. This happened because multiple pathobiological processes may contribute to the disease progression, which

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Qiu-ming Yao, Bin Wang, Xiao-fei An, Jin-an Zhang and Liumei Ding

Introduction Diabetes is a public health issue, and there are over 0.4 billion people suffering from diabetes over the world, and its prevalence is still increasing remarkably every year ( 1 ). Type 2 diabetes mellitus (T2DM) is the major type

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Emanuela Zaharieva, Zdravko Kamenov, Tsvetelina Velikova, Adelina Tsakova, Yosif El-Darawish and Haruki Okamura

helper immune response ( 3 , 4 ). Apart from its place in immune defense against infective pathogens, IL-18 participates in the pathogenesis of atopic, autoimmune and chronic inflammatory diseases ( 3 , 4 ). Obesity and type 2 diabetes (T2D) have been

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Xiangyu Gao, Wanwan Sun, Yi Wang, Yawen Zhang, Rumei Li, Jinya Huang and Yehong Yang

). Historically, based on positivity of islet autoantibodies, diabetes mellitus had been classified into two clinical types: type 1 diabetes (T1DM) and type 2 diabetes (T2DM) ( 3 , 4 ). The progressive destruction of islet β cell mass caused by islet autoimmunity

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Dmitry M Davydov and Malik K Nurbekov

Introduction Despite the known limitations of diagnostic criteria and early risk for type 2 diabetes derived from fasting (FPG) and/or 2-h plasma glucose levels, they are still widely accepted. Glycated hemoglobin A1 or the percentage of total

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David P Sonne, Asger Lund, Jens Faber, Jens J Holst, Tina Vilsbøll and Filip K Knop

-diabetic patients who had undergone Roux-en-Y gastric bypass surgery, and recent reports have demonstrated similar associations of bile acids with TSH in type 2 diabetes (6, 7, 8) . In contrast, Brufau et al . (9) could not demonstrate any effect of bile acids

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Jothydev Kesavadev, Pradeep Babu Sadasivan Pillai, Arun Shankar, Gopika Krishnan and Sunitha Jothydev

glucose homoeostasis without increasing the risk of hypoglycemia and weight gain ( 4 ). Addition of sitagliptin, a DPP-4 inhibitor for treatment of type 2 diabetes mellitus (T2DM) in patients poorly controlled on insulin with or without metformin, has been

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Alessandra Gambineri and Carla Pelusi

Role of sex and gender on the development of type 2 diabetes There is increasing evidence that sex and gender differences influence the epidemiology, pathophysiology, treatment and outcomes of many diseases, including type 2 diabetes (T2DM

Open access

Richard H Tuligenga

Introduction Patients with type 2 diabetes mellitus show faster cognitive decline compared with healthy subjects (1) . Numerous studies in patients with type 2 diabetes have dealt with the association between the level of glycaemic control and the

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Ram P Narayanan, Bo Fu, Adrian H Heald, Kirk W Siddals, Robert L Oliver, Julie E Hudson, Antony Payton, Simon G Anderson, Anne White, William E R Ollier and J Martin Gibson

the renal glomerulus (3) . In this study, we used ‘real-world’ data to examine the hypothesis that concentrations of IGF2 and IGFBP2 at baseline were associated with longitudinal trends in glomerular filtration rate (GFR) in type 2 diabetes. Subjects