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Zhou-Qing Kang, Jia-Ling Huo and Xiao-Jie Zhai

was the first use of glucose range 80–110 mg/dL to define tight glycemic control (TGC), and then tight control of glycemic target became popular. Many researchers have made attempt to practice perioperative TGC with different upper level of glucose

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Yongli Fu, Yaowu Sun, Jiankun Zhang and Yu Cheng

M Cugno M Polli F Taccone P Bellani G Spanu P Pesenti A Iapichino G Gattinoni L. Tight glycemic control may favor fibrinolysis in patients with sepsis . Critical Care Medicine 2009 37 424 – 431 . (

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Wang Chengji and Fan Xianjin

-treated T2DM patients failed to prove any protective effect of tight glycemic control ( 11 ). High levels of tPA have been shown to be predictive of future T2DM independent of metabolic syndrome ( 12 , 13 ). Another study showed that tPA and PAI-1 levels