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M Langeveld, C Y Tan, M R Soeters, S Virtue, G K Ambler, L P E Watson, P R Murgatroyd, V K Chatterjee and A Vidal-Puig

-shivering thermogenesis (NST) is the increase in energy expenditure resulting from exposure to temperatures below the thermoneutral zone, but above the temperature threshold for shivering. By definition, no physiological mechanisms for temperature regulation are active at

Open access

Florian W Kiefer

production (thermogenesis) ( 4 , 7 ). This process has long been believed to occur exclusively in brown adipocytes; however, in recent years, a large number of studies have reported about the emergence of UCP-1-positive cells in WAT with very similar

Open access

Stephen A Martin, Kenneth A Philbrick, Carmen P Wong, Dawn A Olson, Adam J Branscum, Donald B Jump, Charles K Marik, Jonathan M DenHerder, Jennifer L Sargent, Russell T Turner and Urszula T Iwaniec

basal metabolic level and decreased core body temperature ( 2 , 8 ). Conversely, when food intake and locomotor activity are increased during the dark photoperiod, mice utilize energy-requiring adaptive thermogenesis to help maintain sufficient core

Open access

Nese Cinar and Alper Gurlek

metabolic rate, increase in energy expenditure, modulation of responsiveness to catecholamines, and thermogenesis in adipose tissue (3, 4) . Disturbances in thyroid function lead to changes in body weight, muscle mass, and fat tissue. Thyroid

Open access

Lianghui You, Yan Wang, Yao Gao, Xingyun Wang, Xianwei Cui, Yanyan Zhang, Lingxia Pang, Chenbo Ji, Xirong Guo and Xia Chi

demonstrated that the activation of thermogenesis in fat could produce a healthier metabolic phenotype with traits such as whole-body energy metabolism, improved glucose homeostasis, and weight loss ( 2 , 3 ). Moreover, functional BAT was discovered in adult

Open access

Volha V Zhukouskaya, Anya Rothenbuhler, Annamaria Colao, Carolina Di Somma, Peter Kamenický, Séverine Trabado, Dominique Prié, Christelle Audrain, Anna Barosi, Christèle Kyheng, Anne-Sophie Lambert and Agnès Linglart

level and BMI. On the other hand, phosphorus supplementation for 3 months significantly decreased body weight, BMI, waist circumference; restored diet-induced thermogenesis; and increased post-prandial satiety in obese/overweight subjects ( 10 , 11

Open access

Michaela Keuper

involvement of catecholamine-producing ATMΦ is controversially discussed ( 28 , 29 ). Although some reports on catecholamine synthesis in MΦ exist ( 143 , 155 , 156 ), the physiological contribution during cold-induced thermogenesis seems to be of minor

Open access

Rajae Talbi and Victor M Navarro

POMC neurons Kiss1 ARC neurons project to a wide variety of brain nuclei including central metabolic centers known to regulate food intake, body weight and thermogenesis: the median preoptic nucleus (MePO), bed nucleus of the stria terminalis (BnST

Open access

Hong-Fa Yan, Zhao-Yu Liu, Zhi-Ang Guan and Chuang Guo

tissues. The data are presented as the mean ±  s.d. ( n  = 8). * P  < 0.05 compared with the vehicle control. To further evaluate the effect of DFO treatment on activation of adipogenesis and thermogenesis, we measured the expression levels of

Open access

Peter Wolf, Yvonne Winhofer, Martin Krššák and Michael Krebs

lipid metabolism ( 53 ) and result in a significantly increased risk for cardiovascular diseases in hypothyroid patients ( 54 ). Thyroid hormones stimulate energy expenditure by promoting mitochondrial uncoupling and inducing thermogenesis in humans