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Qiu-ming Yao, Bin Wang, Xiao-fei An, Jin-an Zhang and Liumei Ding

T2DM are still necessary to copy with the epidemic of T2DM. There is evidence to indicate that endogenous sex hormones play a vital role in the pathogenesis of T2DM ( 4 ). Some studies proposed that testosterone was possibly linked with T2DM risk

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Mélanie Rouleau, Francis Lemire, Michel Déry, Benoît Thériault, Gabriel Dubois, Yves Fradet, Paul Toren, Chantal Guillemette, Louis Lacombe, Laurence Klotz, Fred Saad, Dominique Guérette and Frédéric Pouliot

Introduction Androgen deprivation therapy (ADT) is used to treat recurrent and advanced PCa ( 1 , 2 ). ADT blocks the testicular production of androgens thus inhibiting PCa cell growth ( 3 ). Serum testosterone levels are a prognostic factor

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Jin Kyu Oh, Young Jae Im, Kwanjin Park and Jae-Seung Paick

, albeit with no hypospadias, as indicated by normal morphology of the urethral meatus at the tip of the glans penis. Micropenis is commonly associated with testosterone deficiencies from 12 weeks of gestation, with normal placental human chorionic

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Lawrence D Hayes, Peter Herbert, Nicholas F Sculthorpe and Fergal M Grace

Introduction Testosterone is a sex steroid hormone with profound influence on various tissues ( 1 , 2 , 3 ). The precipitous decline in systemic testosterone with age is well described ( 4 ). Additionally, sex hormone-binding globulin (SHBG

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P Herbert, LD Hayes, NF Sculthorpe and FM Grace

Introduction Peak muscle power is an important determinant of athletic performance across the lifespan that declines with age ( 1 ) and is accompanied by a precipitous decline in serum testosterone ( 2 ). Both present a noteworthy impediment

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Kristin Ottarsdottir, Anna G Nilsson, Margareta Hellgren, Ulf Lindblad and Bledar Daka

Introduction Testosterone plays a key role in the regulation of glucose and lipid metabolism in men ( 1 ) and women ( 2 ) although in different manners. Low concentrations of testosterone in men are associated with obesity ( 3 ), the metabolic

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Manjeetkaur Sehemby, Prachi Bansal, Vijaya Sarathi, Ashwini Kolhe, Kanchan Kothari, Swati Jadhav-Ramteke, Anurag R Lila, Tushar Bandgar and Nalini S Shah

), hormonal evaluation (follicle-stimulating hormone (FSH), luteinizing hormone (LH) and testosterone), imaging details (transabdominal sonography, computed tomography/magnetic resonance imaging), surgical details and follow-up of the patients were collected

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Teresa Lam, Mark McLean, Amy Hayden, Anne Poljak, Birinder Cheema, Howard Gurney, Glenn Stone, Neha Bahl, Navneeta Reddy, Haleh Shahidipour and Vita Birzniece

Introduction Sarcopenia, the age-related loss of muscle mass and function, presents an escalating public health burden, contributing to increased falls, disability and loss of functional independence ( 1 ). In men, testosterone is critical for

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Milène Tetsi Nomigni, Sophie Ouzounian, Alice Benoit, Jacqueline Vadrot, Frédérique Tissier, Sylvie Renouf, Hervé Lefebvre, Sophie Christin-Maitre and Estelle Louiset

hyperandrogenism (5, 6) . They are commonly associated with high testosterone levels (7, 8) . High plasma levels of testosterone associated with normal dehydroepiandrosterone sulfate (DHEAS) concentration are indicative of ovarian hyperthecosis or androgen

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Christian Trummer, Stefan Pilz, Verena Schwetz, Barbara Obermayer-Pietsch and Elisabeth Lerchbaum

-based studies found that in 30–40% of infertile couples, the underlying cause is the male factor ( 13 ). One major aspect regarding male fertility is the complex interaction between pituitary gland and testis. Of note, testosterone is not only an important