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K E Lines, R P Vas Nunes, M Frost, C J Yates, M Stevenson and R V Thakker

help to overcome such limitations, as illustrated by use of a tamoxifen-inducible knockout of the Men1 gene, activated by fusing a pan-active human ubiquitin C9 (UBC9) promoter to Cre recombinase and a modified oestrogen receptor (ER), to create a