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Nicola Tufton, Lucy Shapiro, Anju Sahdev, Ajith V Kumar, Lee Martin, William M Drake, Scott A Akker and Helen L Storr

transformation ( 7 , 8 ). Approximately 72% of metastatic PPGLs in childhood are associated with SDHB mutations ( 3 ). This emphasises the importance of lifelong, regular surveillance for all children carrying SDHB mutations in an experienced centre as

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Logan Mills, Panagiotis Drymousis, Yogesh Vashist, Christoph Burdelski, Andreas Prachalias, Parthi Srinivasan, Krishna Menon, Corina Cotoi, Saboor Khan, Judith Cave, Thomas Armstrong, Martin O Weickert, Jakob Izbicki, Joerg Schrader, Andreja Frilling, John K Ramage and Raj Srirajaskanthan

Introduction Small pancreatic neuroendocrine tumours pose a management dilemma between surveillance and resection due to the uncertain natural history of these tumours. The case for surveillance in tumours ≤2 cm is supported by European

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Ruth Therese Casey, Deborah Saunders, Benjamin George Challis, Deborah Pitfield, Heok Cheow, Ashley Shaw and Helen Lisa Simpson

associated with hormone hypersecretion due to improved surveillance and timely initiation of treatment. Currently, malignant pancreatic NETs and thymic carcinoid tumours are recognised as the most common causes of death in MEN1, respectively. Recent data

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Suma Uday, Ardita Kongjonaj, Magda Aguiar, Ted Tulchinsky and Wolfgang Högler

commencement and duration of supplementation; presence of a recommended number of child health surveillance visits, professionals providing care and prescribing vitamin D supplements; provision of financial family support and child care benefits by

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Wafaa M Rashed, Anas Saad, Muneer Al-Husseini, Ahmed Mahmoud Galal, Assem Mohamed Ismael, Ahmed M Al-Tayep, Ayman El Shafie, Mahmoud Ahmed Ali and Ahmad Samir Alfaar

second malignant neoplasm (SMN) ( 4 ). We aim to report the incidence of the adrenal gland malignancies as a second primary malignancy based on the Surveillance, Epidemiology, and End Results ‘SEER’ database. Patients and methods We obtained data

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Natalie Rogowski-Lehmann, Aikaterini Geroula, Aleksander Prejbisz, Henri J L M Timmers, Felix Megerle, Mercedes Robledo, Martin Fassnacht, Stephanie M J Fliedner, Martin Reincke, Anthony Stell, Andrzej Januszewicz, Jacques W M Lenders, Graeme Eisenhofer and Felix Beuschlein

identifying at-risk patients and family members who might benefit from routine surveillance for associated syndromic features. Nevertheless, even for patients without these mutations, there is risk of recurrent disease that can result in cardiovascular

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Eva Jakobsson Ung, Ann-Charlotte Olofsson, Ida Björkman, Tobias Hallén, Daniel S Olsson, Oskar Ragnarsson, Thomas Skoglund, Sofie Jakobsson and Gudmundur Johannsson

adenoma who undergo surgery have tumour remnants needing long-term surveillance and, possibly, additional therapeutic intervention ( 14 ). Patients with pituitary tumours therefore have a complex, life-long disease which they need to master and manage in

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Katherine Van Loon, Li Zhang, Jennifer Keiser, Cendy Carrasco, Katherine Glass, Maria-Teresa Ramirez, Sarah Bobiak, Eric K Nakakura, Alan P Venook, Manisha H Shah and Emily K Bergsland

surveillance and treatment guidelines. Bone metastases pose a considerable risk of complications such as immobilization, loss of independence, and reduced quality of life. Bone metastases from NETs have the potential to result in skeletal-related events (SREs

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Prachi Bansal, Anurag Lila, Manjunath Goroshi, Swati Jadhav, Nilesh Lomte, Kunal Thakkar, Atul Goel, Abhidha Shah, Shilpa Sankhe, Naina Goel, Neelam Jaguste, Tushar Bandgar and Nalini Shah

patients with irregular and infrequent follow-up (mean time to recurrence of 69.2 months). Thus, our findings emphasise the importance of regular biochemical surveillance of patients in remission to detect recurrence before the disease becomes clinically

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Dong Cen, Hui Liu, Zhe Wan, Zhongjie Lin, Yanting Wang, Junjie Xu and Yuelong Liang

prevalence of NEN are steadily increasing ( 1 , 2 ). According to the National Cancer Institute’s Surveillance, Epidemiology, and End Results (SEER) database, the incidence rate of NEN has increased from 1.09 per 100,000 people in 1973 to 6.98 per 100