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Morten Winkler Møller, Marianne Skovsager Andersen, Christian Bonde Pedersen, Bjarne Winther Kristensen and Frantz Rom Poulsen

). For other PAs, except prolactinomas, surgery is the first choice of treatment. The primary surgical technique has been transsphenoidal surgery since Hardy introduced surgical microscopes in 1962 ( 9 ). Further development of this technique has improved

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Chao-bin He, Yu Zhang, Zhi-yuan Cai and Xiao-jun Lin

small numbers of included patients and the absence of unified standards, it is still unclear how much benefit can be obtained from surgery for patients with metastatic PNETs. PNET is a heterogeneous group of tumors and differs both biologically and

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Agnieszka Bogusz, Svenja Boekhoff, Monika Warmuth-Metz, Gabriele Calaminus, Maria Eveslage and Hermann L Müller

 + pHL significantly decreased between 1 and 3 years after surgery for the PEDQOL domains social functionality friends ( P  = 0.050) and family ( P  = 0.016). Decreased QoL was observed during further follow-up in CP with a + pHL when compared with CP

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Eeva M Ryhänen, Ilkka Heiskanen, Harri Sintonen, Matti J Välimäki, Risto P Roine and Camilla Schalin-Jäntti

Introduction The clinical presentation of primary hyperparathyroidism (PHPT) has changed during the last decades. The majority of patients are nowadays asymptomatic with only mild hypercalcaemia (1, 2, 3) . Surgery offers the only opportunity for

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Nidan Qiao

Introduction Cushing’s disease (CD) is a subtype of pituitary adenoma with hypercortisolism and presents a particular challenge to neurosurgeons. Transsphenoidal surgery (TS) has long been the standard of care for patients with CD ( 1 , 2

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Samira M Sadowski, Emanuel Christ, Benoit Bédat, Attila Kollár, Wolfram Karenovics, Aurel Perren, Frédéric Triponez and on behalf of the SwissNET registry

recommendations for best practice: Patients are staged according to the UICC 7th TNM classification and surgery is the recommended therapy of choice in localized disease. Techniques are lobectomy or sleeve resection, with a complete anatomic resection and

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Eva Jakobsson Ung, Ann-Charlotte Olofsson, Ida Björkman, Tobias Hallén, Daniel S Olsson, Oskar Ragnarsson, Thomas Skoglund, Sofie Jakobsson and Gudmundur Johannsson

Introduction Pituitary tumours are rare; for example, the annual incidence of non-functioning pituitary adenomas is 0.65–2.34 per 100,000 ( 1 , 2 , 3 ). Although most pituitary tumours are benign, patients often need to undergo surgery and

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Richard P Steeds, Vandana Sagar, Shishir Shetty, Tessa Oelofse, Harjot Singh, Raheel Ahmad, Elizabeth Bradley, Rachel Moore, Suzanne Vickrage, Stacey Smith, Ivan Yim, Yasir S Elhassan, Hema Venkataraman, John Ayuk, Stephen Rooney and Tahir Shah

be referred to a Cardiologist and seen every 6 months. Medical management of CHD Treatment of CHD should be multidisciplinary, as there are competing demands of both CHD and NET. In some patients, surgery for CHD may be the priority to

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Hongyan Wang, Bin Wu, Zichuan Yao, Xianqing Zhu, Yunzhong Jiang and Song Bai

. These symptoms are often paroxysmal and can be spontaneous or induced by a variety of events, such as strenuous physical exertion, delivery, trauma, anesthesia induction, and surgery ( 3 ). Although the mainstay strategy for treatment of

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Myrtille Fouché, Yves Bouffard, Mary-Charlotte Le Goff, Johanne Prothet, François Malavieille, Pierre Sagnard, Françoise Christin, Davy Hayi-Slayman, Arnaud Pasquer, Gilles Poncet, Thomas Walter and Thomas Rimmelé

Octreotide was administered 12–48 h prior to surgery by intravenous continuous infusion at a dose of 40 µg/h or 80 µg/h if patient had prior CS, hepatic metastases or carcinoid heart disease. Octreotide was continued during the intraoperative and