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Charlotte Höybye Patient Area Endocrinology and Nephrology, Infection and Inflammation Theme, Karolinska University Hospital, Stockholm, Sweden
Department of Molecular Medicine and Surgery, Karolinska Institute, Stockholm, Sweden

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Laia Faseh Department of Molecular Medicine and Surgery, Karolinska Institute, Stockholm, Sweden

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Christos Himonakos Department of Molecular Medicine and Surgery, Karolinska Institute, Stockholm, Sweden
Department of Medicine, Karlstad Hospital, Karlstad, Sweden

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Tomasz Pielak NUTOPI Sp. z o. o., Poznan, Poland

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Jesper Eugen-Olsen Clinical Research Centre, Copenhagen University Hospital Hvidovre, Hvidovre, Denmark

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fibrinolysis ( 15 , 16 ). Binding of uPA to uPAR facilitates cleavage and generation of soluble uPAR (suPAR). suPAR positively correlates to the activation of the inflammatory and immune systems and is present in blood, urine and cerebrospinal fluid ( 15 , 16

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-19-0159
Volume/Issue:
Volume 8: Issue 6
Open access