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C L Bodinham, L Smith, E L Thomas, J D Bell, J R Swann, A Costabile, D Russell-Jones, A M Umpleby and M D Robertson

insulin resistant groups, into similar observations in a T2DM cohort. Using an integrated, whole-body approach, stable isotope tracers to differentiate between changes in hepatic and peripheral insulin sensitivity of glucose uptake, body composition

Open access

Nicolai Preisler, Pascal Laforêt, Karen Lindhardt Madsen, Edith Husu, Christoffer Rasmus Vissing, Gitte Hedermann, Henrik Galbo, Christopher Lindberg and John Vissing

during prolonged (i.e. 1 h) moderate intensity exercise, in patients with Pompe disease. We used cycle-ergometer exercise and stable isotope methodology in combination with indirect calorimetry to determine glucose, glycerol, and fatty acid metabolism

Open access

Ingeborg Brønstad, Lars Breivik, Paal Methlie, Anette S B Wolff, Eirik Bratland, Ingrid Nermoen, Kristian Løvås and Eystein S Husebye

molecular weight of wt 21OH (56 kDa) were cut out for trypsin treatment. Stable isotope-labelled synthetic peptides (N-terminal replacement of lysine ( 13 C 6 , 15 N 2 ) or arginine ( 13 C 6 , 15 N 4 ) respectively) were added in constant amount before

Open access

Kathrin R Frey, Tina Kienitz, Julia Schulz, Manfred Ventz, Kathrin Zopf and Marcus Quinkler

Winterer JC Loriaux DL . Daily cortisol production rate in man determuned by stable isotope dilution/mass spectrometry . Journal of Clinical Endocrinology and Metabolism 1991 72 39 – 45 . ( ) 10.1210/jcem-72

Open access

María L Bacigalupo, Verónica G Piazza, Nadia S Cicconi, Pablo Carabias, Andrzej Bartke, Yimin Fang, Ana I Sotelo, Gabriel A Rabinovich, María F Troncoso and Johanna G Miquet

. ( ) 28839427 23 Yeh CC Hsu CH Shao YY Ho WC Tsai MH Feng WC Chow LP . Integrated Stable Isotope Labeling by amino Acids in Cell Culture (SILAC) and Isobaric Tags for Relative and Absolute

Open access

Vickie Braithwaite, Kerry S Jones, Shima Assar, Inez Schoenmakers and Ann Prentice

status and intestinal integrity Two-day weighed dietary assessment was conducted using Gambian food composition tables (26) in the same way as described previously (13) . H. pylori infection was determined using a non-invasive stable isotope urea

Open access

J A Tamblyn, C Jenkinson, D P Larner, M Hewison and M D Kilby

.01.049 ) 10.1016/j.jchromb.2016.01.049 40 Ogawa S Ooki S Shinoda K Higashi T. Analysis of urinary vitamin D(3) metabolites by liquid chromatography/tandem mass spectrometry with ESI-enhancing and stable isotope-coded derivatization . Analytical and

Open access

Paal Methlie, Steinar Hustad, Ralf Kellman, Bjørg Almås, Martina M Erichsen, Eystein S Husebye and Kristian Løvås

, Analytical Technologies in the Biomedical and Life Sciences 883–884 2012 50 – 58 . ( doi:10.1016/j.jchromb.2011.08.027 ). 27 Wang S Cyronak M Yang E . Does a stable isotopically labeled internal standard always correct analyte response? A matrix effect

Open access

Teresa Lam, Mark McLean, Amy Hayden, Anne Poljak, Birinder Cheema, Howard Gurney, Glenn Stone, Neha Bahl, Navneeta Reddy, Haleh Shahidipour and Vita Birzniece

, coefficients of variation (CVs) for LRa and Lox are 3.5 and 6.1% respectively ( 18 ). Hepatic urea production The rate of urea production was measured by the urea turnover technique using stable isotope methodology with 15 N 2 -Urea as tracer, as

Open access

Arno Téblick, Lies Langouche and Greet Van den Berghe

-ACTH-driven mechanisms. By using stable isotopes, elevated cortisol levels could indeed be attributed to suppressed cortisol metabolism, and, only in patients suffering from hyperinflammation, to a moderately increased cortisol production ( 47 ). The attenuated cortisol