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and down-regulates the sodium/iodide symporter gene in Frtl-5 cells . Endocrinology 1999 140 5705 – 5711 . ( https://doi.org/10.1210/endo.140.12.7197 ) 6 Kovacs K Vasarhelyi B Gyarmati B Karvaly G . Estrogen metabolism during pregnancy
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multiple proteins such as thyroid peroxidase (TPO), thyroglobulin (TG), and sodium iodide symporter (NIS) ( 2 , 3 ). NIS is a key protein that mediates active iodine uptake in the thyroid follicular epithelial cells. This procedure is the first critical