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Yutong Zou Division of Nephrology, West China Hospital of Sichuan University, Chengdu, Sichuan, China
Laboratory of Diabetic Kidney Disease, Centre of Diabetes and Metabolism Research, West China Hospital of Sichuan University, Chengdu, Sichuan, China

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Lijun Zhao Division of Nephrology, West China Hospital of Sichuan University, Chengdu, Sichuan, China
Laboratory of Diabetic Kidney Disease, Centre of Diabetes and Metabolism Research, West China Hospital of Sichuan University, Chengdu, Sichuan, China

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Junlin Zhang Division of Nephrology, West China Hospital of Sichuan University, Chengdu, Sichuan, China
Laboratory of Diabetic Kidney Disease, Centre of Diabetes and Metabolism Research, West China Hospital of Sichuan University, Chengdu, Sichuan, China

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Yiting Wang Division of Nephrology, West China Hospital of Sichuan University, Chengdu, Sichuan, China
Laboratory of Diabetic Kidney Disease, Centre of Diabetes and Metabolism Research, West China Hospital of Sichuan University, Chengdu, Sichuan, China

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Yucheng Wu Division of Nephrology, West China Hospital of Sichuan University, Chengdu, Sichuan, China
Laboratory of Diabetic Kidney Disease, Centre of Diabetes and Metabolism Research, West China Hospital of Sichuan University, Chengdu, Sichuan, China

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Honghong Ren Division of Nephrology, West China Hospital of Sichuan University, Chengdu, Sichuan, China
Laboratory of Diabetic Kidney Disease, Centre of Diabetes and Metabolism Research, West China Hospital of Sichuan University, Chengdu, Sichuan, China

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Tingli Wang Division of Nephrology, West China Hospital of Sichuan University, Chengdu, Sichuan, China
Laboratory of Diabetic Kidney Disease, Centre of Diabetes and Metabolism Research, West China Hospital of Sichuan University, Chengdu, Sichuan, China

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Rui Zhang Division of Nephrology, West China Hospital of Sichuan University, Chengdu, Sichuan, China
Laboratory of Diabetic Kidney Disease, Centre of Diabetes and Metabolism Research, West China Hospital of Sichuan University, Chengdu, Sichuan, China

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Jiali Wang Division of Nephrology, West China Hospital of Sichuan University, Chengdu, Sichuan, China
Laboratory of Diabetic Kidney Disease, Centre of Diabetes and Metabolism Research, West China Hospital of Sichuan University, Chengdu, Sichuan, China

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Yuancheng Zhao Division of Nephrology, West China Hospital of Sichuan University, Chengdu, Sichuan, China
Laboratory of Diabetic Kidney Disease, Centre of Diabetes and Metabolism Research, West China Hospital of Sichuan University, Chengdu, Sichuan, China

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Chunmei Qin Division of Nephrology, West China Hospital of Sichuan University, Chengdu, Sichuan, China
Laboratory of Diabetic Kidney Disease, Centre of Diabetes and Metabolism Research, West China Hospital of Sichuan University, Chengdu, Sichuan, China

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Huan Xu Division of Pathology, West China Hospital of Sichuan University, Chengdu, Sichuan, China

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Lin Li Division of Pathology, West China Hospital of Sichuan University, Chengdu, Sichuan, China

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Zhonglin Chai Department of Diabetes, Central Clinical School, Monash University, Melbourne, Australia

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Mark E Cooper Department of Diabetes, Central Clinical School, Monash University, Melbourne, Australia

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Nanwei Tong Division of Endocrinology, West China Hospital of Sichuan University, Chengdu, Sichuan, China
Centre of Diabetes and Metabolism Research, West China Hospital of Sichuan University, Chengdu, Sichuan, China

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Fang Liu Division of Nephrology, West China Hospital of Sichuan University, Chengdu, Sichuan, China
Laboratory of Diabetic Kidney Disease, Centre of Diabetes and Metabolism Research, West China Hospital of Sichuan University, Chengdu, Sichuan, China

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the last decade. In China Kidney Disease Network 2015 annual data report, diabetes-related kidney disease is now the leading cause of chronic kidney disease (CKD), accounting for 26.96% ( 2 ). Serum uric acid (SUA) level has been widely recognized as

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-21-0307
Volume/Issue:
Volume 10: Issue 10
Open access
Rong Xu Center for Endocrine Metabolism and Immune Diseases, Lu He Hospital, Capital Medical University, Beijing, China
Beijing Key Laboratory of Diabetes Research and Care, Beijing, China

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Difei Lian Center for Endocrine Metabolism and Immune Diseases, Lu He Hospital, Capital Medical University, Beijing, China
Beijing Key Laboratory of Diabetes Research and Care, Beijing, China

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Yan Xie Center for Endocrine Metabolism and Immune Diseases, Lu He Hospital, Capital Medical University, Beijing, China
Beijing Key Laboratory of Diabetes Research and Care, Beijing, China

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Lin Mu Center for Endocrine Metabolism and Immune Diseases, Lu He Hospital, Capital Medical University, Beijing, China
Beijing Key Laboratory of Diabetes Research and Care, Beijing, China

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Yali Wu Center for Endocrine Metabolism and Immune Diseases, Lu He Hospital, Capital Medical University, Beijing, China
Beijing Key Laboratory of Diabetes Research and Care, Beijing, China

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Zhilei Chen Center for Endocrine Metabolism and Immune Diseases, Lu He Hospital, Capital Medical University, Beijing, China
Beijing Key Laboratory of Diabetes Research and Care, Beijing, China

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Baoyu Zhang Center for Endocrine Metabolism and Immune Diseases, Lu He Hospital, Capital Medical University, Beijing, China
Beijing Key Laboratory of Diabetes Research and Care, Beijing, China

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antioxidant property ( 7 ). Hyperuricemia (HUA) is defined as the level of serum uric acid (sUA) >6.0 mg/dL (>360 µmol/L) for females and >7.0 mg/dL (>420 µmol/L) for males ( 8 ). Elevated sUA levels may lead to the deposition of urate crystals in the joints

Article Type:
Review Article
Collections:
Bone and Mineral Metabolism
DOI:
https://doi.org/10.1530/EC-23-0040
Volume/Issue:
Volume 12: Issue 11
Open access
Zhenyu Liu Department of Clinical Medicine, Beijing Luhe Hospital, Capital Medical University, Tongzhou District, Beijing, China

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Huixi Kong Department of Clinical Medicine, Beijing Shijitan Hospital, Capital Medical University, Haidian District, Beijing, China

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Baoyu Zhang Center for Endocrine Metabolism and Immune Diseases, Beijing Luhe Hospital, Capital Medical University, Tongzhou District, Beijing, China

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mechanisms mainly include metformin, thiazolidinediones (TZDs) α-glucosidase inhibitors, and sodium–glucose cotransporter 2 inhibitors (SGLT2i). The formation of serum uric acid (SUA) is the ribose 5-phosphate, a pentose derived from glycidic metabolism

Article Type:
Review Article
Collections:
Metabolic Syndrome and Diabetes
DOI:
https://doi.org/10.1530/EC-24-0070
Volume/Issue:
Volume 13: Issue 6
Open access
Ying Hua Department of Administrative Office, The First People's Hospital of Xiaoshan District, Xiaoshan Affiliated Hospital of Wenzhou Medical University, Hangzhou, Zhejiang, China

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Jinqiong Fang Department of Administrative Office, The First People's Hospital of Xiaoshan District, Xiaoshan Affiliated Hospital of Wenzhou Medical University, Hangzhou, Zhejiang, China

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Xiaocong Yao Department of Osteoporosis Care and Control, The First People's Hospital of Xiaoshan District, Xiaoshan Affiliated Hospital of Wenzhou Medical University, Hangzhou, Zhejiang, China

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Zhongxin Zhu Department of Osteoporosis Care and Control, The First People's Hospital of Xiaoshan District, Xiaoshan Affiliated Hospital of Wenzhou Medical University, Hangzhou, Zhejiang, China
Department of Clinical Research Center, The First People's Hospital of Xiaoshan District, Xiaoshan Affiliated Hospital of Wenzhou Medical University, Hangzhou, Zhejiang, China

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doctor to have diabetes or with a HbA1c ≥6.5%), total protein, blood urea nitrogen, serum uric acid, serum phosphorus, and serum calcium levels, as continuous variables; and gender, race, educational level, moderate recreational activities, and smoked at

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-21-0352
Volume/Issue:
Volume 10: Issue 10
Open access
Yunyi Ding Department of Nephrology, Hangzhou TCM Hospital of Zhejiang Chinese Medical University, Hangzhou, China

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Siyao Lv Department of Gastroenterology, Hangzhou TCM Hospital of Zhejiang Chinese Medical University, Hangzhou, China

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Ruijie Xie Division of Clinical Epidemiology and Aging Research, University of Heidelberg, Heidelberg, Germany

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Wei Ye Department of Gastroenterology, Hangzhou TCM Hospital, Hangzhou, China

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Yichen Luo School of Mechanical Engineering, Zhejiang University, Hangzhou, China

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Yayu Li Department of Nephrology, Hangzhou TCM Hospital, Hangzhou, China

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closely related to the kidneys function, such as ACR (mg/g), serum creatinine (mg/dL), serum uric acid (mg/dL), eGFR (mL/min/1.73 m 2 ), and others related to obesity, metabolism, such as total cholesterol (mg/dL), triglycerides (mg/dL), high

Article Type:
Research Article
Collections:
Metabolic Syndrome and Diabetes
DOI:
https://doi.org/10.1530/EC-23-0491
Volume/Issue:
Volume 13: Issue 4
Open access
Yuka Goto Division of Endocrinology and Metabolism, Department of Internal Medicine, Kurume University School of Medicine, Asahi-machi, Kurume-city, Fukuoka, Japan

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Yoshie Otsuka Division of Endocrinology and Metabolism, Department of Internal Medicine, Kurume University School of Medicine, Asahi-machi, Kurume-city, Fukuoka, Japan

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Kenji Ashida Division of Endocrinology and Metabolism, Department of Internal Medicine, Kurume University School of Medicine, Asahi-machi, Kurume-city, Fukuoka, Japan

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Ayako Nagayama Division of Endocrinology and Metabolism, Department of Internal Medicine, Kurume University School of Medicine, Asahi-machi, Kurume-city, Fukuoka, Japan

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Nao Hasuzawa Division of Endocrinology and Metabolism, Department of Internal Medicine, Kurume University School of Medicine, Asahi-machi, Kurume-city, Fukuoka, Japan

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Shimpei Iwata Division of Endocrinology and Metabolism, Department of Internal Medicine, Kurume University School of Medicine, Asahi-machi, Kurume-city, Fukuoka, Japan

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Kento Hara Division of Endocrinology and Metabolism, Department of Internal Medicine, Kurume University School of Medicine, Asahi-machi, Kurume-city, Fukuoka, Japan

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Munehisa Tsuruta Division of Endocrinology and Metabolism, Department of Internal Medicine, Kurume University School of Medicine, Asahi-machi, Kurume-city, Fukuoka, Japan

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Nobuhiko Wada Division of Endocrinology and Metabolism, Department of Internal Medicine, Kurume University School of Medicine, Asahi-machi, Kurume-city, Fukuoka, Japan

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Seiichi Motomura Division of Endocrinology and Metabolism, Department of Internal Medicine, Kurume University School of Medicine, Asahi-machi, Kurume-city, Fukuoka, Japan
Division of Endocrinology and Metabolism, Diabetes Center, Kurume Medical Center, Kokubu-machi, Kurume-city, Fukuoka, Japan

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Yuji Tajiri Division of Endocrinology and Metabolism, Department of Internal Medicine, Kurume University School of Medicine, Asahi-machi, Kurume-city, Fukuoka, Japan
Division of Endocrinology and Metabolism, Diabetes Center, Kurume Medical Center, Kokubu-machi, Kurume-city, Fukuoka, Japan

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Masatoshi Nomura Division of Endocrinology and Metabolism, Department of Internal Medicine, Kurume University School of Medicine, Asahi-machi, Kurume-city, Fukuoka, Japan

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composition, glucose metabolism, serum uric acid and lipid metabolism, and urinary glucose excretion, did not show any significant correlations with the log GIR ( Table 2 ). Table 1 Baseline participant characteristics ( n  = 20). Variables

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-20-0082
Volume/Issue:
Volume 9: Issue 7
Open access
Xiangyu Gao Department of Endocrinology, Huashan Hospital, Fudan University, Shanghai, China

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Wanwan Sun Department of Endocrinology, Huashan Hospital, Fudan University, Shanghai, China

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Yi Wang Department of Endocrinology, Huashan Hospital, Fudan University, Shanghai, China

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Yawen Zhang Department of Endocrinology, Huashan Hospital, Fudan University, Shanghai, China

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Rumei Li Department of Endocrinology, Huashan Hospital, Fudan University, Shanghai, China

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Jinya Huang Department of Endocrinology, Huashan Hospital, Fudan University, Shanghai, China

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Yehong Yang Department of Endocrinology, Huashan Hospital, Fudan University, Shanghai, China

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-density lipoprotein (cholesterol); mALB, urinary microalbumin; TCHOL, total cholesterol; TG, triglycerides; UA, serum uric acid; Ucr, urine creatinine; WHR, waist-hip ratio. Correlation of islet autoantibodies with clinical characteristics in community

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-19-0379
Volume/Issue:
Volume 8: Issue 11
Open access
Line K Johnson Morbid Obesity Centre, Department of Nutrition, Norwegian National Advisory Unit on Familial Hypercholesterolemia, Department of Gynecology, Institute of Clinical Medicine, Department of Endocrinology, Vestfold Hospital Trust, PO Box 2168, 3103 Tønsberg, Norway

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Kirsten B Holven Morbid Obesity Centre, Department of Nutrition, Norwegian National Advisory Unit on Familial Hypercholesterolemia, Department of Gynecology, Institute of Clinical Medicine, Department of Endocrinology, Vestfold Hospital Trust, PO Box 2168, 3103 Tønsberg, Norway
Morbid Obesity Centre, Department of Nutrition, Norwegian National Advisory Unit on Familial Hypercholesterolemia, Department of Gynecology, Institute of Clinical Medicine, Department of Endocrinology, Vestfold Hospital Trust, PO Box 2168, 3103 Tønsberg, Norway

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Njord Nordstrand Morbid Obesity Centre, Department of Nutrition, Norwegian National Advisory Unit on Familial Hypercholesterolemia, Department of Gynecology, Institute of Clinical Medicine, Department of Endocrinology, Vestfold Hospital Trust, PO Box 2168, 3103 Tønsberg, Norway

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Jan R Mellembakken Morbid Obesity Centre, Department of Nutrition, Norwegian National Advisory Unit on Familial Hypercholesterolemia, Department of Gynecology, Institute of Clinical Medicine, Department of Endocrinology, Vestfold Hospital Trust, PO Box 2168, 3103 Tønsberg, Norway

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Tom Tanbo Morbid Obesity Centre, Department of Nutrition, Norwegian National Advisory Unit on Familial Hypercholesterolemia, Department of Gynecology, Institute of Clinical Medicine, Department of Endocrinology, Vestfold Hospital Trust, PO Box 2168, 3103 Tønsberg, Norway
Morbid Obesity Centre, Department of Nutrition, Norwegian National Advisory Unit on Familial Hypercholesterolemia, Department of Gynecology, Institute of Clinical Medicine, Department of Endocrinology, Vestfold Hospital Trust, PO Box 2168, 3103 Tønsberg, Norway

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Jøran Hjelmesæth Morbid Obesity Centre, Department of Nutrition, Norwegian National Advisory Unit on Familial Hypercholesterolemia, Department of Gynecology, Institute of Clinical Medicine, Department of Endocrinology, Vestfold Hospital Trust, PO Box 2168, 3103 Tønsberg, Norway
Morbid Obesity Centre, Department of Nutrition, Norwegian National Advisory Unit on Familial Hypercholesterolemia, Department of Gynecology, Institute of Clinical Medicine, Department of Endocrinology, Vestfold Hospital Trust, PO Box 2168, 3103 Tønsberg, Norway

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added as a sweetening ingredient. Human studies and animal models have demonstrated that fructose increases serum uric acid levels (12, 13) . A rise in uric acid levels inhibits nitric oxide availability (13) . Because insulin requires nitric oxide to

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-15-0047
Volume/Issue:
Volume 4: Issue 3
Open access
Jun-Xin Yan The First Clinical Medical College, Lanzhou University, Lanzhou, Gansu, China

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Bin-Jing Pan The First Clinical Medical College, Lanzhou University, Lanzhou, Gansu, China

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Ping-Ping Zhao The First Clinical Medical College, Lanzhou University, Lanzhou, Gansu, China

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Li-Ting Wang The First Clinical Medical College, Lanzhou University, Lanzhou, Gansu, China
Department of Endocrinology, The First Hospital of Lanzhou University, Lanzhou, Gansu, China

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Jing-Fang Liu The First Clinical Medical College, Lanzhou University, Lanzhou, Gansu, China
Department of Endocrinology, The First Hospital of Lanzhou University, Lanzhou, Gansu, China

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Song-Bo Fu The First Clinical Medical College, Lanzhou University, Lanzhou, Gansu, China
Department of Endocrinology, The First Hospital of Lanzhou University, Lanzhou, Gansu, China

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.1016/j.dsx.2019.05.030 ) 23 Lombardi R Pisano G Fargion S . Role of serum uric acid and ferritin in the development and progression of NAFLD . International Journal of Molecular Sciences 2016 17 548. ( https://doi.org/10.3390/ijms17040548

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DOI:
https://doi.org/10.1530/EC-21-0367
Volume/Issue:
Volume 10: Issue 12
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Jing Hong Department of Endocrinology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China

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Wen-Yue Liu Department of Endocrinology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China

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Xiang Hu Department of Endocrinology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China

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Fei-Fei Jiang Department of Endocrinology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China

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Ze-Ru Xu Department of Endocrinology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China

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Fang Li Department of Endocrinology, Ruian Traditional Chinese Medicine Hospital, Wenzhou, China

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Fei-Xia Shen Department of Endocrinology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China

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Hong Zhu Department of Endocrinology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China

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-specific association between serum uric acid and prolonged corrected QT interval: result from a general rural Chinese population . Medicine 2016 95 e5568. ( https://doi.org/10.1097/MD.0000000000005568 ) 33 van Noord C Sturkenboom MC Straus SM Hofman A

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DOI:
https://doi.org/10.1530/EC-21-0140
Volume/Issue:
Volume 10: Issue 8
Open access