Search Results

You are looking at 1 - 10 of 550 items for :

Clear All
Open access

Ruth Therese Casey, Deborah Saunders, Benjamin George Challis, Deborah Pitfield, Heok Cheow, Ashley Shaw and Helen Lisa Simpson

viability, thereby contributing to carcinogenesis. The probability of tumour induction occurs in proportion to the magnitude of radiation dose exposure ( 6 , 7 ). The effective dose (ED), referred to as cumulative effective dose (CED), quantifies the risk

Open access

Katica Bajuk Studen and Marija Pfeifer

, impaired glucose tolerance or frank type 2 diabetes, low-grade inflammation and increased pro-thrombotic state ( 2 ). This high prevalence of cardiovascular risk factors in PCOS is assumed to be associated with accelerated cardiovascular disease. However

Open access

Andrea V Haas, Paul N Hopkins, Nancy J Brown, Luminita H Pojoga, Jonathan S Williams, Gail K Adler and Gordon H Williams

, individuals with incidentally discovered adrenal masses and biochemical work-up consistent with subclinical Cushing’s syndrome also have increased cardiometabolic risk ( 2 , 3 , 4 , 5 , 6 ). Even among individuals with biochemical work-up consistent with

Open access

Anne M Drewes, Maria E Møller, Rasmus Hertzum-Larsen, Gerda Engholm and Hans H Storm

-term follow-up allows us to study common risk factors and consequences of the treatment. Schoenberg in 1975 ( 1 ) and Helseth in 1989 ( 2 ) already demonstrated an increased risk of meningioma in breast cancer patients from Connecticut and Norway, respectively

Open access

Jeonghoon Ha, Jeongmin Lee, Kwanhoon Jo, Dong-Jun Lim, Moo Il Kang, Bong Yun Cha and Min-Hee Kim

cases, thyroid hormone replacement can be considered in pregnant patients who have TSH persistently >10 µIU/mL, associated symptoms or are at high risk of overt hypothyroidism ( 2 , 3 ). SCH is frequently detected in the population with a prevalence of

Open access

Sanna Mustaniemi, Marja Vääräsmäki, Johan G Eriksson, Mika Gissler, Hannele Laivuori, Hilkka Ijäs, Aini Bloigu, Eero Kajantie and Laure Morin-Papunen

conditions ( 8 , 9 ). GDM and PCOS can be early signs of an increased risk of manifest diseases related to insulin resistance, such as type 2 diabetes (T2D), and both disorders are also connected with cardiovascular risk factors, such as metabolic syndrome

Open access

Tingting Xia, Hongru Sun, Hao Huang, Haoran Bi, Rui Pu, Lei Zhang, Yuanyuan Zhang, Ying Liu, Jing Xu, Justina Ucheojor Onwuka, Yupeng Liu, Binbin Cui and Yashuang Zhao

accumulating evidence suggests that sex hormones are relevant to its development ( 3 ). There is an observational phenomenon and clinical evidence suggesting that men tend to have a much higher risk of CRC than women of the same age ( 4 ). As one of the most

Open access

Angelo Maria Patti, Kalliopi Pafili, Nikolaos Papanas and Manfredi Rizzo

) within 2–20 years ( 3 , 4 ) and 17–63% developed type 2 diabetes mellitus (T2DM) and obesity within 5–16 years ( 5 , 6 , 7 ). Longitudinal studies have shown that women with prior GDM and obesity were at higher risk to develop MetS compared with those

Open access

Katherine A Bolton, Kelly A Avery-Kiejda, Elizabeth G Holliday, John Attia, Nikola A Bowden and Rodney J Scott

deaths ( 2 ). The incidence of both of these hormone-related cancers has been steadily increasing in Australia and other Western and developing countries over the past 20 years ( 3 , 4 , 5 ). Oestrogen exposure is a major risk factor for these cancers

Open access

Qiu-ming Yao, Bin Wang, Xiao-fei An, Jin-an Zhang and Liumei Ding

they fail to maintain stable glucose control; furthermore, oral medications are associated with adverse effects that are involved in hypoglycemia, weight gain and the loss of bone ( 3 ). Therefore, further studies of the pathogenesis and risk factors of