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Lei Gao
Lei Gao
Department of Geriatrics, Nanjing Drum Tower Hospital Clinical College of Nanjing Medical University, Nanjing, China
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Wenxia Cui
Wenxia Cui
Department of Geriatrics, Nanjing Drum Tower Hospital Clinical College of Nanjing Medical University, Nanjing, China
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Dinghuang Mu
Dinghuang Mu
Department of Geriatrics, Nanjing Drum Tower Hospital Clinical College of Nanjing University of Chinese Medicine, Nanjing, China
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Shaoping Li
Shaoping Li
Department of Health Management Center, Nanjing Drum Tower Hospital Clinical College of Nanjing Medical University, Nanjing, China
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Nan Li
Nan Li
Department of Geriatrics, Nanjing Drum Tower Hospital Clinical College of Nanjing Medical University, Nanjing, China
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Weihong Zhou
Weihong Zhou
Department of Health Management Center, Nanjing Drum Tower Hospital Clinical College of Nanjing Medical University, Nanjing, China
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Yun Hu
Yun Hu
Department of Geriatrics, Nanjing Drum Tower Hospital Clinical College of Nanjing Medical University, Nanjing, China
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Objective
To create a nomogram-based model to estimate the Chinese population's 5-year risk of metabolic dysfunction-associated steatotic liver disease (MASLD).
Methods
We randomly divided 7582 participants into two groups in a 7:3 ratio: one group was assigned to work with the training set, which consisted of 5307 cases, and the other group was assigned to validate the model using 2275 cases. The least absolute shrinkage and selection operator model was employed to ascertain the variables with the highest correlation among all potential variables. A logistic model was constructed by incorporating these selected variables, which were subsequently visualized using a nomogram. The discriminatory ability, calibration, and clinical utility of the model were assessed using the receiver operating characteristic (ROC) curve, calibration curve, and decision curve analysis (DCA).
Results
During the 5-year follow-up, 1034 (13.64%) total participants were newly diagnosed with MASLD. Using eight variables (gender, body mass index, waist, hemoglobin, alanine aminotransferase, uric acid, triglycerides, and high-density lipoprotein), we built a 5-year MASLD risk prediction model. The nomogram showed an area under the ROC of 0.795 (95% CI: 0.779–0.811) in the training set and 0.785 (95% CI: 0.760–0.810) in the validation set. The calibration curves revealed a 5-year period of agreement between the observed and predicted MASLD risks. DCA curves illustrated the practicality of this nomogram over threshold probability profiles ranging from 5% to 50%.
Conclusion
We created and tested a nomogram to forecast the risk of MASLD prevalence over the next 5 years.
Yuan Fang
Yuan Fang
Department of Epidemiology, School of Public Health and Key Laboratory of Public Health Safety, Fudan University, Shanghai, China
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Xuehong Zhang
Xuehong Zhang
Channing Division of Network Medicine, Department of Medicine, Brigham and Women’s Hospital, Boston, Massachusetts, USA
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Huilin Xu
Huilin Xu
Center for Disease Control and Prevention of Minhang District, Shanghai, China
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Stephanie A Smith-Warner
Stephanie A Smith-Warner
Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA
Department of Nutrition, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA
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Department of Nutrition, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA
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Dongli Xu
Dongli Xu
Center for Disease Control and Prevention of Minhang District, Shanghai, China
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Hong Fang
Hong Fang
Center for Disease Control and Prevention of Minhang District, Shanghai, China
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Wang Hong Xu
Wang Hong Xu
Department of Epidemiology, School of Public Health and Key Laboratory of Public Health Safety, Fudan University, Shanghai, China
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retrospective cohort study based on a standardized T2DM management system in Shanghai, China, we estimated the risk of cancer, overall and by site, by the time since diagnoses in Chinese patients newly diagnosed with T2DM, to evaluate the influence of T2DM on
Zhou Zheng
Zhou Zheng
Department of Medical Laboratory, The Affiliated Luohu Hospital of Shenzhen University, Shenzhen University, Shenzhen, Guangdong, China
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Xiuming Zhang
Xiuming Zhang
Department of Medical Laboratory, The Affiliated Luohu Hospital of Shenzhen University, Shenzhen University, Shenzhen, Guangdong, China
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Fanggui Wu
Fanggui Wu
Department of Reproductive Medicine, The Affiliated Luohu Hospital of Shenzhen University, Shenzhen University, Shenzhen, Guangdong, China
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Haizhen Liao
Haizhen Liao
Department of Reproductive Medicine, The Affiliated Luohu Hospital of Shenzhen University, Shenzhen University, Shenzhen, Guangdong, China
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Huan Zhao
Huan Zhao
Department of Reproductive Medicine, The Affiliated Luohu Hospital of Shenzhen University, Shenzhen University, Shenzhen, Guangdong, China
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Minqi Zhang
Minqi Zhang
Department of Reproductive Medicine, The Affiliated Luohu Hospital of Shenzhen University, Shenzhen University, Shenzhen, Guangdong, China
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Shangjie Liu
Shangjie Liu
Department of Reproductive Medicine, The Affiliated Luohu Hospital of Shenzhen University, Shenzhen University, Shenzhen, Guangdong, China
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stimulation protocol in women who received the GnRH agonist long-acting protocol or the GnRH antagonist protocol: a retrospective cohort study . Frontiers in Endocrinology 2022 13 899000 . ( https://doi.org/10.3389/fendo.2022.899000 ) 29 Adebayo FO Ameh
Nardin Aslih
Nardin Aslih
Department of Obstetrics and Gynecology, MDIVF Unit, Hillel Yaffe Medical Center, IsraelTechnion – Israel Institute of Technology, Hadera, Haifa, Israel
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Mediea Michaeli
Mediea Michaeli
Department of Obstetrics and Gynecology, MDIVF Unit, Hillel Yaffe Medical Center, IsraelTechnion – Israel Institute of Technology, Hadera, Haifa, Israel
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Diana Mashenko
Diana Mashenko
Department of Obstetrics and Gynecology, MDIVF Unit, Hillel Yaffe Medical Center, IsraelTechnion – Israel Institute of Technology, Hadera, Haifa, Israel
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Adrian Ellenbogen
Adrian Ellenbogen
Department of Obstetrics and Gynecology, MDIVF Unit, Hillel Yaffe Medical Center, IsraelTechnion – Israel Institute of Technology, Hadera, Haifa, Israel
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Oshrit Lebovitz
Oshrit Lebovitz
Department of Obstetrics and Gynecology, MDIVF Unit, Hillel Yaffe Medical Center, IsraelTechnion – Israel Institute of Technology, Hadera, Haifa, Israel
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Yuval Atzmon
Yuval Atzmon
Department of Obstetrics and Gynecology, MDIVF Unit, Hillel Yaffe Medical Center, IsraelTechnion – Israel Institute of Technology, Hadera, Haifa, Israel
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Einat Shalom-Paz
Einat Shalom-Paz
Department of Obstetrics and Gynecology, MDIVF Unit, Hillel Yaffe Medical Center, IsraelTechnion – Israel Institute of Technology, Hadera, Haifa, Israel
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administration, number of oocytes retrieved, number of mature oocytes, fertilization rate, number of top-quality embryos and numbers of embryos transferred or cryopreserved. Materials and methods Patients In this retrospective cohort study, records of
Hsiao-Yun Yeh
Hsiao-Yun Yeh
Department of Medical Education, Taipei Veterans General Hospital, Taipei, Taiwan
Faculty of Medicine, School of Medicine, National Yang-Ming Chiao Tung University, Taipei, Taiwan
Department of Family Medicine, Taipei Veterans General Hospital, Taipei, Taiwan
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Faculty of Medicine, School of Medicine, National Yang-Ming Chiao Tung University, Taipei, Taiwan
Department of Family Medicine, Taipei Veterans General Hospital, Taipei, Taiwan
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Hung-Ta Hondar Wu
Hung-Ta Hondar Wu
Faculty of Medicine, School of Medicine, National Yang-Ming Chiao Tung University, Taipei, Taiwan
Division of Musculoskeletal Section, Department of Radiology, Taipei Veterans General Hospital, Taipei, Taiwan
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Division of Musculoskeletal Section, Department of Radiology, Taipei Veterans General Hospital, Taipei, Taiwan
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Hsiao-Chin Shen
Hsiao-Chin Shen
Department of Medical Education, Taipei Veterans General Hospital, Taipei, Taiwan
Faculty of Medicine, School of Medicine, National Yang-Ming Chiao Tung University, Taipei, Taiwan
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Faculty of Medicine, School of Medicine, National Yang-Ming Chiao Tung University, Taipei, Taiwan
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Tzu-Hao Li
Tzu-Hao Li
Division of Allergy, Immunology, and Rheumatology, Department of Internal Medicine, Shin Kong Wu Ho-Su Memorial Foundation, Taipei, Taiwan
School of Medicine, College of Medicine, Fu Jen Catholic University, New Taipei, Taiwan
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School of Medicine, College of Medicine, Fu Jen Catholic University, New Taipei, Taiwan
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Ying-Ying Yang
Ying-Ying Yang
Department of Medical Education, Taipei Veterans General Hospital, Taipei, Taiwan
Faculty of Medicine, School of Medicine, National Yang-Ming Chiao Tung University, Taipei, Taiwan
Division of Gastroenterology and Hepatology, Department of Internal Medicine, Taipei Veterans General Hospital, Taipei, Taiwan
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Faculty of Medicine, School of Medicine, National Yang-Ming Chiao Tung University, Taipei, Taiwan
Division of Gastroenterology and Hepatology, Department of Internal Medicine, Taipei Veterans General Hospital, Taipei, Taiwan
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Kuei-Chuan Lee
Kuei-Chuan Lee
Faculty of Medicine, School of Medicine, National Yang-Ming Chiao Tung University, Taipei, Taiwan
Division of Gastroenterology and Hepatology, Department of Internal Medicine, Taipei Veterans General Hospital, Taipei, Taiwan
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Division of Gastroenterology and Hepatology, Department of Internal Medicine, Taipei Veterans General Hospital, Taipei, Taiwan
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Yi-Hsuan Lin
Yi-Hsuan Lin
Department of Medical Education, Taipei Veterans General Hospital, Taipei, Taiwan
Faculty of Medicine, School of Medicine, National Yang-Ming Chiao Tung University, Taipei, Taiwan
Department of Family Medicine, Taipei Veterans General Hospital, Taipei, Taiwan
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Faculty of Medicine, School of Medicine, National Yang-Ming Chiao Tung University, Taipei, Taiwan
Department of Family Medicine, Taipei Veterans General Hospital, Taipei, Taiwan
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Chia-Chang Huang
Chia-Chang Huang
Department of Medical Education, Taipei Veterans General Hospital, Taipei, Taiwan
Faculty of Medicine, School of Medicine, National Yang-Ming Chiao Tung University, Taipei, Taiwan
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Faculty of Medicine, School of Medicine, National Yang-Ming Chiao Tung University, Taipei, Taiwan
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Ming-Chih Hou
Ming-Chih Hou
Faculty of Medicine, School of Medicine, National Yang-Ming Chiao Tung University, Taipei, Taiwan
Division of Gastroenterology and Hepatology, Department of Internal Medicine, Taipei Veterans General Hospital, Taipei, Taiwan
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Division of Gastroenterology and Hepatology, Department of Internal Medicine, Taipei Veterans General Hospital, Taipei, Taiwan
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. Our retrospective cohort study, conducted between 2011 and 2019, aimed to investigate the combined effect of FL and BMI on future fracture risk, a topic that has been relatively underinvestigated in prior research. To this end, we performed a sex
Margret J Einarsdottir
Margret J Einarsdottir
Department of Internal Medicine and Clinical Nutrition, Institute of Medicine at Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden
Department of Endocrinology, Sahlgrenska University Hospital, Gothenburg, Sweden
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Department of Endocrinology, Sahlgrenska University Hospital, Gothenburg, Sweden
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Penelope Trimpou
Penelope Trimpou
Department of Internal Medicine and Clinical Nutrition, Institute of Medicine at Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden
Department of Endocrinology, Sahlgrenska University Hospital, Gothenburg, Sweden
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Department of Endocrinology, Sahlgrenska University Hospital, Gothenburg, Sweden
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Gudmundur Johannsson
Gudmundur Johannsson
Department of Internal Medicine and Clinical Nutrition, Institute of Medicine at Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden
Department of Endocrinology, Sahlgrenska University Hospital, Gothenburg, Sweden
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Department of Endocrinology, Sahlgrenska University Hospital, Gothenburg, Sweden
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Oskar Ragnarsson
Oskar Ragnarsson
Department of Internal Medicine and Clinical Nutrition, Institute of Medicine at Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden
Department of Endocrinology, Sahlgrenska University Hospital, Gothenburg, Sweden
Wallenberg Center for Molecular and Translational Medicine, University of Gothenburg, Gothenburg, Sweden
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Department of Endocrinology, Sahlgrenska University Hospital, Gothenburg, Sweden
Wallenberg Center for Molecular and Translational Medicine, University of Gothenburg, Gothenburg, Sweden
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lack of stress dose administration. Thus, group A includes cases 1, 2, 4, and 6, and group B includes cases 3 and 5. Discussion This retrospective cohort study, including 300 randomly selected GC users who died from sepsis, shows that a
Jes Sloth Mathiesen
Jes Sloth Mathiesen
Department of ORL Head & Neck Surgery and Audiology, Odense University Hospital, Odense, Denmark
Department of Clinical Research, University of Southern Denmark, Odense, Denmark
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Department of Clinical Research, University of Southern Denmark, Odense, Denmark
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Jens Peter Kroustrup
Jens Peter Kroustrup
Department of Clinical Medicine and Endocrinology, Aalborg University Hospital, Aalborg, Denmark
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Peter Vestergaard
Peter Vestergaard
Department of Clinical Medicine and Endocrinology, Aalborg University Hospital, Aalborg, Denmark
Steno Diabetes Center North Jutland, Aalborg, Denmark
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Steno Diabetes Center North Jutland, Aalborg, Denmark
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Per Løgstrup Poulsen
Per Løgstrup Poulsen
Department of Internal Medicine and Endocrinology, Aarhus University Hospital, Aarhus, Denmark
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Åse Krogh Rasmussen
Åse Krogh Rasmussen
Department of Medical Endocrinology, Copenhagen University Hospital, Copenhagen, Denmark
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Ulla Feldt-Rasmussen
Ulla Feldt-Rasmussen
Department of Medical Endocrinology, Copenhagen University Hospital, Copenhagen, Denmark
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Sten Schytte
Sten Schytte
Department of ORL Head & Neck Surgery, Aarhus University Hospital, Aarhus, Denmark
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Stefano Christian Londero
Stefano Christian Londero
Department of ORL Head & Neck Surgery, Aarhus University Hospital, Aarhus, Denmark
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Henrik Baymler Pedersen
Henrik Baymler Pedersen
Department of ORL Head & Neck Surgery, Aalborg University Hospital, Aalborg, Denmark
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Christoffer Holst Hahn
Christoffer Holst Hahn
Department of ORL Head & Neck Surgery, Copenhagen University Hospital, Copenhagen, Denmark
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Jens Bentzen
Jens Bentzen
Department of Oncology, Herlev Hospital, Herlev, Denmark
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Sören Möller
Sören Möller
Department of Clinical Research, University of Southern Denmark, Odense, Denmark
Odense Patient data Explorative Network (OPEN), Odense University Hospital, Odense, Denmark
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Odense Patient data Explorative Network (OPEN), Odense University Hospital, Odense, Denmark
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Mette Gaustadnes
Mette Gaustadnes
Department of Molecular Medicine, Aarhus University Hospital, Aarhus, Denmark
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Maria Rossing
Maria Rossing
Center for Genomic Medicine, Copenhagen University Hospital, Copenhagen, Denmark
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Finn Cilius Nielsen
Finn Cilius Nielsen
Center for Genomic Medicine, Copenhagen University Hospital, Copenhagen, Denmark
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Kim Brixen
Kim Brixen
Department of Clinical Research, University of Southern Denmark, Odense, Denmark
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Christian Godballe
Christian Godballe
Department of ORL Head & Neck Surgery and Audiology, Odense University Hospital, Odense, Denmark
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Danish Thyroid Cancer Group (DATHYRCA)
Danish Thyroid Cancer Group (DATHYRCA)
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. Patients and methods Patients This retrospective cohort study included 191 unique patients diagnosed with MTC in Denmark between January 1, 1997, and December 31, 2014. An MTC cohort, initially comprising 476 patients diagnosed with MTC in Denmark
Kazhan Mollazadegan
Kazhan Mollazadegan
Department of Medical Sciences, Uppsala University, Uppsala, Sweden
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Britt Skogseid
Britt Skogseid
Department of Medical Sciences, Uppsala University, Uppsala, Sweden
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Johan Botling
Johan Botling
Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden
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Tobias Åkerström
Tobias Åkerström
Department of Surgical Sciences, Uppsala University, Uppsala, Sweden
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Barbro Eriksson
Barbro Eriksson
Department of Medical Sciences, Uppsala University, Uppsala, Sweden
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Staffan Welin
Staffan Welin
Department of Medical Sciences, Uppsala University, Uppsala, Sweden
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Anders Sundin
Anders Sundin
Department of Surgical Sciences, Uppsala University, Uppsala, Sweden
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Joakim Crona
Joakim Crona
Department of Medical Sciences, Uppsala University, Uppsala, Sweden
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Epidemiology Guidelines ( 18 ). Study design, setting and participants This was a single-center retrospective cohort study at Uppsala University Hospital, Uppsala, Sweden. Patients were included when they fulfilled the following criteria: (i
Monica F Stecchini
Monica F Stecchini
Department of Pediatrics, Ribeirao Preto Medical School, University of Sao Paulo, Ribeirao Preto, Sao Paulo, Brazil
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Zilda Braid
Zilda Braid
Department of Pediatrics, Ribeirao Preto Medical School, University of Sao Paulo, Ribeirao Preto, Sao Paulo, Brazil
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Candy B More
Candy B More
Department of Pediatrics, Ribeirao Preto Medical School, University of Sao Paulo, Ribeirao Preto, Sao Paulo, Brazil
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Davi C Aragon
Davi C Aragon
Department of Pediatrics, Ribeirao Preto Medical School, University of Sao Paulo, Ribeirao Preto, Sao Paulo, Brazil
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Margaret Castro
Margaret Castro
Department of Internal Medicine, Ribeirao Preto Medical School, University of Sao Paulo, Ribeirao Preto, Sao Paulo, Brazil
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Ayrton C Moreira
Ayrton C Moreira
Department of Internal Medicine, Ribeirao Preto Medical School, University of Sao Paulo, Ribeirao Preto, Sao Paulo, Brazil
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Sonir R Antonini
Sonir R Antonini
Department of Pediatrics, Ribeirao Preto Medical School, University of Sao Paulo, Ribeirao Preto, Sao Paulo, Brazil
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Study design and patients This was a retrospective cohort study performed at the Hospital of Ribeirao Preto Medical School from the University of Sao Paulo (Brazil). The study was approved by this institution’s ethics committee and conducted in
Punith Kempegowda
Punith Kempegowda
Institute of Metabolism and Systems Research, University of Birmingham, Birmingham, UK
University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK
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University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK
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Eka Melson
Eka Melson
Institute of Metabolism and Systems Research, University of Birmingham, Birmingham, UK
University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK
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University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK
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Agnes Johnson
Agnes Johnson
College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK
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Lucy Wallett
Lucy Wallett
College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK
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Lucretia Thomas
Lucretia Thomas
College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK
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Dengyi Zhou
Dengyi Zhou
College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK
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Catherine Holmes
Catherine Holmes
University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK
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Agata Juszczak
Agata Juszczak
University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK
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Mohammed Ali Karamat
Mohammed Ali Karamat
University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK
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Sandip Ghosh
Sandip Ghosh
University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK
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Wasim Hanif
Wasim Hanif
University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK
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Parth Narendran
Parth Narendran
University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK
Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, UK
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Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, UK
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Srikanth Bellary
Srikanth Bellary
University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK
School of Life and Health Sciences, Aston University, Birmingham, UK
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School of Life and Health Sciences, Aston University, Birmingham, UK
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retrospective cohort study of all patients with DKA in our institution from 01 March 2020 to 30 May 2020. Based on the SARS-coronavirus-PCR test results, patients were categorised into COVID-positive and COVID-negative groups. Further, to enable comparison with
