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Yun Hu, Na Li, Peng Jiang, Liang Cheng, Bo Ding, Xiao-Mei Liu, Ke He, Yun-Qing Zhu, Bing-li Liu, Xin Cao, Hong Zhou and Xiao-Ming Mao

). Previous studies have proved that Tg could induce lymphocytic thyroiditis by elevating Tg-Ab titers in BB/Wor rats ( 15 ) by activating T cells ( 16 ). In addition, a number of studies underlined the important roles of regulatory T cells (Tregs) on the

Open access

Changwei Liu, Jingwen Wang, Yuanyuan Wan, Xiaona Xia, Jian Pan, Wei Gu and Mei Li

Graninger W Borkenstein M , et al . Cholecalciferol supplementation improves suppressive capacity of regulatory T-cells in young patients with new-onset type 1 diabetes mellitus – A randomized clinical trial . Clinical Immunology 2015 161 217 – 224

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Mengxue Yang, Bowen Sun, Jianhui Li, Bo Yang, Jie Xu, Xue Zhou, Jie Yu, Xuan Zhang, Qun Zhang, Shan Zhou and Xiaohua Sun

T Momose Y Cheng G Yamasaki S Saito T Ohba Y , et al . Induction of colonic regulatory T cells by indigenous Clostridium species . Science 2011 331 . ( https://doi.org/10.1126/science.1198469 ) 21205640 11 Heyma P Harrison LC

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Borros Arneth

regulatory T-cells by IgG Fc–derived peptide ‘Tregitopes.’ Blood 2008 112 3303 – 3311 . ( doi:10.1182/blood-2008-02-138073 ) 18660382 10.1182/blood-2008-02-138073 10 Schatz D Krischer J Horne G Riley W Spillar R Silverstein J

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Elizabeth Yan Zhang and Bao-Ting Zhu

in thymic and autoimmune T cells . Journal of Gender-Specific Medicine 1999 2 33 – 40 . 29 Tai P Wang J Jin H Song X Yan J Kang Y Zhao L An X Du X Chen X . Induction of regulatory T cells by physiological level estrogen

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Emmi Naskali, Katja Dettmer, Peter J Oefner, Pedro A B Pereira, Kai Krohn, Petri Auvinen, Annamari Ranki and Nicolas Kluger

it is responsible for the elimination of potentially autoreactive cytotoxic T-cells, which in APECED will destroy target cells. Due to the loss of AIRE function, APECED patients also have a lack of regulatory T-cells and, thus, APECED is characterized

Open access

Weiwei He, Bin Wang, Kaida Mu, Jing Zhang, Yanping Yang, Wei Yao, Sheli Li and Jin-an Zhang

-antigen and anti-metastatic effects ( 28 ), and may play a key role in the antitumor immune response by regulating the production of T helper 1 (Th1)/Th2 bias and regulatory T cells (Treg) ( 29 ). IL27 induces cytotoxic T lymphocyte production by inducing

Open access

Taís S Assmann, Mariana Recamonde-Mendoza, Bianca M De Souza and Daisy Crispim

a promotes regulatory T cells and suppresses autoimmune diabetes in mice . Inflammation 2016 39 1 – 9 . ( doi:10.1007/s10753-015-0215-0 ) 10.1007/s10753-015-0215-0 26208605 62 Nabih ES Andrawes NG. The association between

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Marra Jai Aghajani, Tara Laurine Roberts, Tao Yang, Charles Eugenio McCafferty, Nicole J Caixeiro, Paul DeSouza and Navin Niles

+ T cells into regulatory T cells (Tregs), ultimately protecting the tumour from immune-mediated rejection. We have recently completed a meta-analysis confirming that elevated tumour PD-L1 is a prognostic indicator for reduced DFS in patients with non

Open access

Legh Wilkinson, Nicolette J D Verhoog and Ann Louw

ligand of glucocorticoid receptors, increases regulatory T cells and M2 macrophages to attenuate experimental autoimmune neuritis with reduced side effects . Journal of Immunology 2009 183 3081 – 3091 . ( https://doi.org/10.4049/jimmunol.0901088