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Université Paris Cité, Faculté de Santé, UFR de Médecine, Paris, France
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Université Paris Cité, Faculté de Santé, UFR de Médecine, Paris, France
Inserm UMR1185, Le Kremlin Bicetre, Paris, France
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Inserm UMR1185, Le Kremlin Bicetre, Paris, France
Paris-Saclay University, Paris, France
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administration of gonadotropins (recombinant LH and FSH) for 6 months was the other modality, through a pump connected to a subcutaneous catheter (pump group). Materials and methods Patients CHH patients treated with gonadotropins between 2004 and
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Wren Laboratories, Yale University School of Medicine, 35 NE Industrial Road, Branford, Connecticut, USA
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a variety of cardiac and inflammatory diseases (14) as well as in renal failure (15) . One of the commonest causes of spuriously elevated CgA levels is proton pump inhibitor (PPI) administration (10) . A third of the USA population has been
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Cambridge University Hospitals NHS Foundation Trust, Wolfson Diabetes and Endocrine Clinic, Cambridge, UK
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insulin a century ago. Continuous subcutaneous insulin infusion (CSII) pumps were first developed in the 1970s and have since markedly reduced in size and increased in capability. Continuous glucose monitoring (CGM) devices, measuring real
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Introduction Diabetes devices are rapidly advancing in their features and functionalities, offering a range of benefits for individuals with type 1 diabetes who opt to use this technology. Current diabetes technology includes insulin pumps
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pumps, which often can pair directly with CGM to automate background insulin delivery, therefore achieving a higher time in range compared to insulin pens. However, there are numerous reasons why people may not want to be or may not be able to be on an
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Diabetes Centre, Departments of Internal Medicine, General Practice, Langerhans Medical Research Group, Department of Internal Medicine, Division of Cell Biology, Faculty of Health Sciences, Isala Clinics, PO Box 10400, 8000 G.K. Zwolle, The Netherlands
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Diabetes Centre, Departments of Internal Medicine, General Practice, Langerhans Medical Research Group, Department of Internal Medicine, Division of Cell Biology, Faculty of Health Sciences, Isala Clinics, PO Box 10400, 8000 G.K. Zwolle, The Netherlands
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Diabetes Centre, Departments of Internal Medicine, General Practice, Langerhans Medical Research Group, Department of Internal Medicine, Division of Cell Biology, Faculty of Health Sciences, Isala Clinics, PO Box 10400, 8000 G.K. Zwolle, The Netherlands
Diabetes Centre, Departments of Internal Medicine, General Practice, Langerhans Medical Research Group, Department of Internal Medicine, Division of Cell Biology, Faculty of Health Sciences, Isala Clinics, PO Box 10400, 8000 G.K. Zwolle, The Netherlands
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Diabetes Centre, Departments of Internal Medicine, General Practice, Langerhans Medical Research Group, Department of Internal Medicine, Division of Cell Biology, Faculty of Health Sciences, Isala Clinics, PO Box 10400, 8000 G.K. Zwolle, The Netherlands
Diabetes Centre, Departments of Internal Medicine, General Practice, Langerhans Medical Research Group, Department of Internal Medicine, Division of Cell Biology, Faculty of Health Sciences, Isala Clinics, PO Box 10400, 8000 G.K. Zwolle, The Netherlands
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Diabetes Centre, Departments of Internal Medicine, General Practice, Langerhans Medical Research Group, Department of Internal Medicine, Division of Cell Biology, Faculty of Health Sciences, Isala Clinics, PO Box 10400, 8000 G.K. Zwolle, The Netherlands
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administration using an implantable pump. These two groups (start i.p. or continue s.c.) differed only in the sequence of the mode of insulin administration. Randomization was carried out using sealed non-transparent envelopes, with adequate blinding of the
Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark
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Department of Clinical Biochemistry, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark
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Department of Clinical Biochemistry, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark
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Department of Pediatrics, Copenhagen University Hospital - Herlev & Gentofte, Copenhagen, Denmark
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Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark
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, a sterile single-use cartridge with tubing, a reservoir for flushing solution, pumps and filter paper, and a sterile single-use multi-lumen catheter. This allows up to 20 h of unattended serial microsampling of maximum of 20 DBS samples of 3–10 μL
Department of Diabetes and Endocrinology, Skåne University Hospital, Malmö, Sweden
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Department of Clinical Sciences, Lund University, Malmö, Sweden
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Department of Plastic Surgery, Skåne University Hospital, Malmö, Sweden
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Department of Ophthalmology, Skåne University Hospital, Malmö, Sweden
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Department of Diabetes and Endocrinology, Skåne University Hospital, Malmö, Sweden
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Department of Diabetes and Endocrinology, Skåne University Hospital, Malmö, Sweden
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–120 min. Cigarette smoke was extracted using a validated peristaltic pump system ( 20 , 21 ). Standard differentiation cocktail containing 1 µM rosiglitazone (Sigma), 1 µM dexamethasone (Sigma) and 1.7 µM insulin (Sigma) was then added and replaced by
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The concept of the heart as an endocrine organ arises from the observation that the atrial cardiomyocytes in the mammalian heart display a phenotype that is partly that of endocrine cells. Investigations carried out between 1971 and 1983 characterised, by virtue of its natriuretic properties, a polypeptide referred to atrial natriuretic factor (ANF). Another polypeptide isolated from brain in 1988, brain natriuretic peptide (BNP), was subsequently characterised as a second hormone produced by the mammalian heart atria. These peptides were associated with the maintenance of extracellular fluid volume and blood pressure. Later work demonstrated a plethora of other properties for ANF and BNP, now designated cardiac natriuretic peptides (cNPs). In addition to the cNPs, other polypeptide hormones are expressed in the heart that likely act upon the myocardium in a paracrine or autocrine fashion. These include the C-type natriuretic peptide, adrenomedullin, proadrenomedullin N-terminal peptide and endothelin-1. Expression and secretion of ANF and BNP are increased in various cardiovascular pathologies and their levels in blood are used in the diagnosis and prognosis of cardiovascular disease. In addition, therapeutic uses for these peptides or related substances have been found. In all, the discovery of the endocrine heart provided a shift from the classical functional paradigm of the heart that regarded this organ solely as a blood pump to one that regards this organ as self-regulating its workload humorally and that also influences the function of several other organs that control cardiovascular function.
Mary & Dick Allen Diabetes Center at Hoag Hospital, Newport Beach, California, USA
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, 14 , 15 , 16 , 17 , 18 , 19 , 20 , 21 , 22 , 23 , 24 , 25 ). The subanalyses reviewed seven general concepts: (i) are insulin pumps better than MDI in neonatal and maternal outcomes? (ii) were dietary patterns different in the treatment
