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adrenocortical carcinomas: a strategy toward improved personalized prognostication . Journal of Clinical Endocrinology and Metabolism 2018 103 4511 – 4523 . ( https://doi.org/10.1210/jc.2018-01348 ) 12 Zheng S Cherniack AD Dewal N Moffitt RA Danilova
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observed in adult patients. Additional mutations in thyroid cancer prognostication Next-generation sequencing studies have shown that compared to DTC, PDTC and ATC display an extended set of mutations but typically harbor driver alterations in BRAF
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/UICC) staging and grading system ( 16 ). Although these have been shown to correlate with survival in large cohorts of patients ( 17 , 18 ), precise prognostication and definition of management strategies for individual patients remain elusive. Significant
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types of thyroid cancers are also refractory to radioactive iodine ( 21 , 22 ). Early diagnosis and prognostication of aggressive thyroid cancer are important for appropriate management, but a better and unambiguous marker is needed. In this study, we
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regrowth or recurrence in any cases of this series. Larger prospective studies are needed to improve our understanding of the nature of these tumours and assist with prognostication in the future. Declaration of interest There is no conflict of
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Gehrig A Steinhauer S , et al. Targeted molecular analysis in adrenocortical carcinomas: a strategy toward improved personalized prognostication . Journal of Clinical Endocrinology and Metabolism 2018 103 4511 – 4523 . ( https://doi.org/10.1210/jc
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Bendel S Kaukonen KM Vaahersalo J Romppanen J Pettilä V Reinikainen M & FINNRESUSCI Study Group . Usefulness of neuron specific enolase in prognostication after cardiac arrest: impact of age and time to ROSC . Resuscitation 2019 139 214
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prognostication of adrenocortical tumors by transcriptome profiling . Clinical Cancer Research 2009 15 668 – 676 . ( doi:10.1158/1078-0432.CCR-08-1067 ). 10 He G Siddik ZH Huang Z Wang R Koomen J Kobayashi R Khokhar AR Kuang J . Induction
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biomarkers (1) . An accurate tumor marker is a critical tool in tumor management, because it establishes an uncertain diagnosis, offers a basis for individual prognostication, signals response to therapy, and identifies relapse. In classical terms, a high
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prognostication . Journal of Clinical Endocrinology & Metabolism 2018 103 4511 – 4523 . ( https://doi.org/10.1210/jc.2018-01348 ) 10 Mohan DR Lerario AM Else T Mukherjee B Almeida MQ Vinco M Rege J Mariani BMP Zerbini MCN Mendonca BB