Tomaž Kocjan
Tomaž Kocjan
Department of Endocrinology, Diabetes and Metabolic Diseases, University Medical Centre Ljubljana, Ljubljana, Slovenia
Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia
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Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia
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Gaj Vidmar
Gaj Vidmar
Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia
University Rehabilitation Institute, Ljubljana, Slovenia
FAMNIT, University of Primorska, Koper, Slovenia
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University Rehabilitation Institute, Ljubljana, Slovenia
FAMNIT, University of Primorska, Koper, Slovenia
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Peter Popović
Peter Popović
Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia
Clinical Institute of Radiology, University Medical Centre Ljubljana, Ljubljana, Slovenia
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Clinical Institute of Radiology, University Medical Centre Ljubljana, Ljubljana, Slovenia
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Milenko Stanković
Milenko Stanković
Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia
Clinical Institute of Radiology, University Medical Centre Ljubljana, Ljubljana, Slovenia
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Clinical Institute of Radiology, University Medical Centre Ljubljana, Ljubljana, Slovenia
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. Hypertension Research 2007 30 1083 – 1095 . ( https://doi.org/10.1291/hypres.30.1083 ) 41 Karashima S Takeda Y Cheng Y Yoneda T Demura M Kometani M Ohe M Mori S Yagi K Yamagishi M . Clinical characteristics of primary hyperaldosteronism
Takuhiro Sonoyama
Takuhiro Sonoyama
Department of Medicine and Clinical Science, Kyoto University Graduate School of Medicine, 54 Shogoin Kawahara-cho, Sakyo-ku, Kyoto 606-8507, Japan
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Masakatsu Sone
Masakatsu Sone
Department of Medicine and Clinical Science, Kyoto University Graduate School of Medicine, 54 Shogoin Kawahara-cho, Sakyo-ku, Kyoto 606-8507, Japan
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Naohisa Tamura
Naohisa Tamura
Department of Medicine and Clinical Science, Kyoto University Graduate School of Medicine, 54 Shogoin Kawahara-cho, Sakyo-ku, Kyoto 606-8507, Japan
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Kyoko Honda
Kyoko Honda
Department of Medicine and Clinical Science, Kyoto University Graduate School of Medicine, 54 Shogoin Kawahara-cho, Sakyo-ku, Kyoto 606-8507, Japan
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Daisuke Taura
Daisuke Taura
Department of Medicine and Clinical Science, Kyoto University Graduate School of Medicine, 54 Shogoin Kawahara-cho, Sakyo-ku, Kyoto 606-8507, Japan
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Katsutoshi Kojima
Katsutoshi Kojima
Department of Medicine and Clinical Science, Kyoto University Graduate School of Medicine, 54 Shogoin Kawahara-cho, Sakyo-ku, Kyoto 606-8507, Japan
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Yorihide Fukuda
Yorihide Fukuda
Department of Medicine and Clinical Science, Kyoto University Graduate School of Medicine, 54 Shogoin Kawahara-cho, Sakyo-ku, Kyoto 606-8507, Japan
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Naotetsu Kanamoto
Naotetsu Kanamoto
Department of Medicine and Clinical Science, Kyoto University Graduate School of Medicine, 54 Shogoin Kawahara-cho, Sakyo-ku, Kyoto 606-8507, Japan
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Masako Miura
Masako Miura
Department of Medicine and Clinical Science, Kyoto University Graduate School of Medicine, 54 Shogoin Kawahara-cho, Sakyo-ku, Kyoto 606-8507, Japan
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Akihiro Yasoda
Akihiro Yasoda
Department of Medicine and Clinical Science, Kyoto University Graduate School of Medicine, 54 Shogoin Kawahara-cho, Sakyo-ku, Kyoto 606-8507, Japan
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Hiroshi Arai
Hiroshi Arai
Department of Medicine and Clinical Science, Kyoto University Graduate School of Medicine, 54 Shogoin Kawahara-cho, Sakyo-ku, Kyoto 606-8507, Japan
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Hiroshi Itoh
Hiroshi Itoh
Department of Medicine and Clinical Science, Kyoto University Graduate School of Medicine, 54 Shogoin Kawahara-cho, Sakyo-ku, Kyoto 606-8507, Japan
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Kazuwa Nakao
Kazuwa Nakao
Department of Medicine and Clinical Science, Kyoto University Graduate School of Medicine, 54 Shogoin Kawahara-cho, Sakyo-ku, Kyoto 606-8507, Japan
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We recently reported that stimulation with high-dose ACTH caused different responses in terms of aldosterone secretion in aldosterone-producing adenomas (APAs) and idiopathic hyperaldosteronism (IHA) in patients with primary aldosteronism (PA). However, the role of endogenous ACTH in aldosterone secretion in PA has not been systematically evaluated. In this study, we examined diurnal changes in plasma aldosterone concentration (PAC), and changes in PAC after dexamethasone administration in patients with suspected PA, in order to evaluate the effect of endogenous ACTH on aldosterone secretion. Seventy-three patients admitted to Kyoto University Hospital with suspected PA were included. The patients were classified into non-PA, IHA, and APA groups according to the results of captopril challenge test and adrenal venous sampling. PAC at 0900 h (PAC0900), 2300 h (PAC2300), and after 1-mg dexamethasone suppression test (PACdex) was measured and compared among the three groups. The PAC2300/PAC0900 and PACdex/PAC0900 ratios were also analyzed. PAC2300 and PACdex were lower than PAC0900 in all three groups. There were no significant differences in PAC2300/PAC0900 among the three groups. However, PACdex/PAC0900 was significantly lower in the APA group compared with the non-PA and IHA groups. The results of this study indicate that aldosterone secretion in APA patients is more strongly dependent on endogenous ACTH than in IHA and non-PA patients. The results also suggest that factors other than ACTH, such as clock genes, may cause diurnal changes in aldosterone secretion in IHA and non-PA patients.
Gamze Akkuş
Gamze Akkuş
Division of Endocrinology, Internal Medicine and Endocrinology, Cukurova University Medical Faculty, Department of Internal Medicine, Adana, Turkey
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Isa Burak Güney
Isa Burak Güney
Nuclear Medicine Department, Cukurova University Medical Faculty, Adana, Turkey
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Fesih Ok
Fesih Ok
Urology Department, Cukurova University Medical Faculty, Adana, Turkey
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Mehtap Evran
Mehtap Evran
Division of Endocrinology, Internal Medicine and Endocrinology, Cukurova University Medical Faculty, Department of Internal Medicine, Adana, Turkey
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Volkan Izol
Volkan Izol
Urology Department, Cukurova University Medical Faculty, Adana, Turkey
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Şeyda Erdoğan
Şeyda Erdoğan
Pathology Department, Cukurova University Medical Faculty, Adana, Turkey
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Yıldırım Bayazıt
Yıldırım Bayazıt
Urology Department, Cukurova University Medical Faculty, Adana, Turkey
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Murat Sert
Murat Sert
Division of Endocrinology, Internal Medicine and Endocrinology, Cukurova University Medical Faculty, Department of Internal Medicine, Adana, Turkey
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Tamer Tetiker
Tamer Tetiker
Division of Endocrinology, Internal Medicine and Endocrinology, Cukurova University Medical Faculty, Department of Internal Medicine, Adana, Turkey
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2.5 ± 1.6 (range 1.7–4.1) 10.17 ± 3.27 Adenoma a 0.001 Pheochromocytoma 4 4.1 ± 2.3 (range 2–6.4) 8.71 ± 2.72 Adenoma b Carcinoma c 0.004 Primary hyperaldosteronism 1 1 3.30 Adenoma – Operated with
Kristin Viste
Kristin Viste
Hormone Laboratory, Department of Medicine, Department of Clinical Science, Department of Radiology, Haukeland University Hospital, 5021 Bergen, Norway
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Marianne A Grytaas
Marianne A Grytaas
Hormone Laboratory, Department of Medicine, Department of Clinical Science, Department of Radiology, Haukeland University Hospital, 5021 Bergen, Norway
Hormone Laboratory, Department of Medicine, Department of Clinical Science, Department of Radiology, Haukeland University Hospital, 5021 Bergen, Norway
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Hormone Laboratory, Department of Medicine, Department of Clinical Science, Department of Radiology, Haukeland University Hospital, 5021 Bergen, Norway
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Melissa D Jørstad
Melissa D Jørstad
Hormone Laboratory, Department of Medicine, Department of Clinical Science, Department of Radiology, Haukeland University Hospital, 5021 Bergen, Norway
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Dag E Jøssang
Dag E Jøssang
Hormone Laboratory, Department of Medicine, Department of Clinical Science, Department of Radiology, Haukeland University Hospital, 5021 Bergen, Norway
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Eivind N Høyden
Eivind N Høyden
Hormone Laboratory, Department of Medicine, Department of Clinical Science, Department of Radiology, Haukeland University Hospital, 5021 Bergen, Norway
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Solveig S Fotland
Solveig S Fotland
Hormone Laboratory, Department of Medicine, Department of Clinical Science, Department of Radiology, Haukeland University Hospital, 5021 Bergen, Norway
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Dag K Jensen
Dag K Jensen
Hormone Laboratory, Department of Medicine, Department of Clinical Science, Department of Radiology, Haukeland University Hospital, 5021 Bergen, Norway
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Kristian Løvås
Kristian Løvås
Hormone Laboratory, Department of Medicine, Department of Clinical Science, Department of Radiology, Haukeland University Hospital, 5021 Bergen, Norway
Hormone Laboratory, Department of Medicine, Department of Clinical Science, Department of Radiology, Haukeland University Hospital, 5021 Bergen, Norway
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Hormone Laboratory, Department of Medicine, Department of Clinical Science, Department of Radiology, Haukeland University Hospital, 5021 Bergen, Norway
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Hrafnkell Thordarson
Hrafnkell Thordarson
Hormone Laboratory, Department of Medicine, Department of Clinical Science, Department of Radiology, Haukeland University Hospital, 5021 Bergen, Norway
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Bjørg Almås
Bjørg Almås
Hormone Laboratory, Department of Medicine, Department of Clinical Science, Department of Radiology, Haukeland University Hospital, 5021 Bergen, Norway
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Gunnar Mellgren
Gunnar Mellgren
Hormone Laboratory, Department of Medicine, Department of Clinical Science, Department of Radiology, Haukeland University Hospital, 5021 Bergen, Norway
Hormone Laboratory, Department of Medicine, Department of Clinical Science, Department of Radiology, Haukeland University Hospital, 5021 Bergen, Norway
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Hormone Laboratory, Department of Medicine, Department of Clinical Science, Department of Radiology, Haukeland University Hospital, 5021 Bergen, Norway
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College of Cardiology 2006 48 2293 – 2300 . ( doi:10.1016/j.jacc.2006.07.059 ). 3 Fardella CE Mosso L Gomez-Sanchez C Cortes P Soto J Gomez L Pinto M Huete A Oestreicher E Foradori A . Primary hyperaldosteronism in essential
Victor Jing-Wei Kang
Victor Jing-Wei Kang
Departments of Medical Imaging, National Taiwan University Hospital, Taipei, Taiwan
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Bo-Ching Lee
Bo-Ching Lee
Departments of Medical Imaging, National Taiwan University Hospital, Taipei, Taiwan
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Jia-Zheng Huang
Jia-Zheng Huang
Departments of Medical Imaging, National Taiwan University Hospital, Taipei, Taiwan
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Vin-Cent Wu
Vin-Cent Wu
Departments of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan
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Yen-Hung Lin
Yen-Hung Lin
Departments of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan
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Chin-Chen Chang
Chin-Chen Chang
Departments of Medical Imaging, National Taiwan University Hospital, Taipei, Taiwan
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TAIPAI group
TAIPAI group
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Papadopoulos N Vogiatzis K & Zamboulis C . Prevalence of primary hyperaldosteronism in resistant hypertension: a retrospective observational study . Lancet 2008 371 1921 – 1926 . ( https://doi.org/10.1016/S0140-6736(0860834-X ) 3 Funder JW Carey
Lukas Engler
Lukas Engler
Medizinische Klinik und Poliklinik IV, Klinikum der Universität München, LMU München, Munchen, Germany
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Christian Adolf
Christian Adolf
Medizinische Klinik und Poliklinik IV, Klinikum der Universität München, LMU München, Munchen, Germany
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Daniel A Heinrich
Daniel A Heinrich
Medizinische Klinik und Poliklinik IV, Klinikum der Universität München, LMU München, Munchen, Germany
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Anna-Katharine Brem
Anna-Katharine Brem
Max-Planck-Institute of Psychiatry, Munich, Germany
Division of Interventional Cognitive Neurology, Department of Neurology, Berenson-Allen Center for Noninvasive Brain Stimulation, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA
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Division of Interventional Cognitive Neurology, Department of Neurology, Berenson-Allen Center for Noninvasive Brain Stimulation, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA
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Anna Riester
Anna Riester
Medizinische Klinik und Poliklinik IV, Klinikum der Universität München, LMU München, Munchen, Germany
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Anna Franke
Anna Franke
Medizinische Klinik und Poliklinik IV, Klinikum der Universität München, LMU München, Munchen, Germany
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Felix Beuschlein
Felix Beuschlein
Medizinische Klinik und Poliklinik IV, Klinikum der Universität München, LMU München, Munchen, Germany
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Martin Reincke
Martin Reincke
Medizinische Klinik und Poliklinik IV, Klinikum der Universität München, LMU München, Munchen, Germany
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Axel Steiger
Axel Steiger
Max-Planck-Institute of Psychiatry, Munich, Germany
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Heike Künzel
Heike Künzel
Medizinische Klinik und Poliklinik IV, Klinikum der Universität München, LMU München, Munchen, Germany
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.1093/ajh/hpu161 25213687 23 Schirpenbach C Segmiller F Diederich S Hahner S Lorenz R Rump LC Seufert J Quinkler M Bidlingmaier M Beuschlein F , The diagnosis and treatment of primary hyperaldosteronism in Germany – results on 555 patients from the
Daisuke Watanabe
Daisuke Watanabe
Department of Endocrinology and Hypertension, Tokyo Women’s Medical University, Shinjuku-ku, Tokyo, Japan
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Satoshi Morimoto
Satoshi Morimoto
Department of Endocrinology and Hypertension, Tokyo Women’s Medical University, Shinjuku-ku, Tokyo, Japan
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Noriko Morishima
Noriko Morishima
Department of Endocrinology and Hypertension, Tokyo Women’s Medical University, Shinjuku-ku, Tokyo, Japan
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Atsuhiro Ichihara
Atsuhiro Ichihara
Department of Endocrinology and Hypertension, Tokyo Women’s Medical University, Shinjuku-ku, Tokyo, Japan
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Arnesen T Glomnes N Strømsøy S Knappskog S Heie A Akslen LA Grytaas M Varhaug JE Gimm O Brauckhoff M Outcome after surgery for primary hyperaldosteronism may depend on KCNJ5 tumor mutation status: a population-based study from Western
Paola Parra Ramírez
Paola Parra Ramírez
Endocrinology & Nutrition Department, La Paz University Hospital, Madrid, Spain
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Patricia Martín Rojas-Marcos
Patricia Martín Rojas-Marcos
Endocrinology & Nutrition Department, La Paz University Hospital, Madrid, Spain
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Miguel Paja Fano
Miguel Paja Fano
Endocrinology & Nutrition Department, Hospital Universitario de Basurto, Bilbao, Spain
Medicine Department, Basque Country University, Bilbao, Spain
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Medicine Department, Basque Country University, Bilbao, Spain
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Marga González Boillos
Marga González Boillos
Endocrinology & Nutrition Department, Hospital Universitario de Castellón, Castellón, Spain
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Eider Pascual-Corrales
Eider Pascual-Corrales
Endocrinology & Nutrition Department, Hospital Universitario Ramón y Cajal, Madrid, Spain
Instituto de Investigación Biomédica Ramón y Cajal (IRYCIS), Madrid, Spain
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Instituto de Investigación Biomédica Ramón y Cajal (IRYCIS), Madrid, Spain
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Ana García-Cano
Ana García-Cano
Biochemistry Department, Hospital Universitario Ramón y Cajal, Madrid, Spain
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Jorge Gabriel Ruiz-Sanchez
Jorge Gabriel Ruiz-Sanchez
Endocrinology & Nutrition Department, Hospital Fundación Jiménez Díaz, Madrid, Spain
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Almudena Vicente
Almudena Vicente
Endocrinology & Nutrition Department, Complejo Universitario de Toledo, Toledo, Spain
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Emilia Gómez-Hoyos
Emilia Gómez-Hoyos
Endocrinology & Nutrition Department, Hospital Clínico Universitario de Valladolid, Valladolid, Spain
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Rui Ferreira
Rui Ferreira
Endocrinology & Nutrition Department, Hospital Universitario de La Princesa, Madrid, Spain
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Iñigo García Sanz
Iñigo García Sanz
General & Digestive Surgery Department, Hospital Universitario de La Princesa, Madrid, Spain
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Mònica Recasens
Mònica Recasens
Endocrinology & Nutrition Department, Hospital Josep Trueta, Servei d’Endocrinologia, Girona, Spain
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Begoña Pla Peris
Begoña Pla Peris
Endocrinology & Nutrition Department, Hospital Universitario de Castellón, Castellón, Spain
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Rebeca Barahona San Millan
Rebeca Barahona San Millan
Endocrinology & Nutrition Department, Hospital Josep Trueta, Servei d’Endocrinologia, Girona, Spain
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María José Picón César
María José Picón César
Endocrinology & Nutrition Department, Complejo Hospitalario Málaga (Hospital Virgen de la Victoria), IBIMA Malaga, Malaga, Spain
CIBEROBN, Madrid, Spain
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CIBEROBN, Madrid, Spain
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Patricia Díaz Guardiola
Patricia Díaz Guardiola
Endocrinology & Nutrition Department, Hospital Universitario Infanta Sofía, Madrid, Spain
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Juan Jesús García González
Juan Jesús García González
Endocrinology & Nutrition Department, Hospital Universitario Virgen de la Macarena, Sevilla, Spain
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Carolina Perdomo
Carolina Perdomo
Endocrinology & Nutrition Department, Clínica Universidad de Navarra, Pamplona, Spain
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Laura Manjón
Laura Manjón
Endocrinology & Nutrition Department, Hospital Universitario Central de Asturias, Oviedo, Spain
Instituto de Investigación Sanitaria del Principado de Asturias (ISPA), Oviedo, Spain
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Instituto de Investigación Sanitaria del Principado de Asturias (ISPA), Oviedo, Spain
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Rogelio García-Centeno
Rogelio García-Centeno
Endocrinology & Nutrition Department, Hospital General Universitario Gregorio Marañón, Madrid, Spain
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Juan Carlos Percovich
Juan Carlos Percovich
Endocrinology & Nutrition Department, Hospital General Universitario Gregorio Marañón, Madrid, Spain
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Ángel Rebollo Román
Ángel Rebollo Román
Endocrinology & Nutrition Department, Hospital Reina Sofía, Córdoba, Spain
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Paola Gracia Gimeno
Paola Gracia Gimeno
Endocrinology & Nutrition Department, Hospital Royo Villanova, Zaragoza, Spain
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Cristina Robles Lázaro
Cristina Robles Lázaro
Endocrinology & Nutrition Department, Hospital Universitario de Salamanca, Salamanca, Spain
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Manuel Morales
Manuel Morales
Biochemistry and Molecular Genetics Department-CDB, Hospital Clinic, IDIBAPS, CIBERehd, Barcelona, Spain
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Felicia Hanzu
Felicia Hanzu
Endocrinology & Nutrition Department, Hospital Clinic, Barcelona, Spain
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Marta Araujo-Castro
Marta Araujo-Castro
Endocrinology & Nutrition Department, Hospital Universitario Ramón y Cajal, Madrid, Spain
Instituto de Investigación Biomédica Ramón y Cajal (IRYCIS), Madrid, Spain
University of Alcalá, Madrid, Spain
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Instituto de Investigación Biomédica Ramón y Cajal (IRYCIS), Madrid, Spain
University of Alcalá, Madrid, Spain
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cardiometabolic profile disappeared after adjusting for hypertension duration. A longer time elapsed between the diagnosis of hypertension and primary hyperaldosteronism was observed in the group of PA ≥65 than in the younger group (10.2 ± 10.26 vs 4.1 ± 7
Sharmin Jahan
Sharmin Jahan
Department of Medicine, Monash University, Melbourne, Victoria, Australia
Centre for Endocrinology and Metabolism, Hudson Institute of Medical Research, Victoria, Australia
Department of Endocrinology and Metabolism, BSMMU, Dhaka, Bangladesh
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Centre for Endocrinology and Metabolism, Hudson Institute of Medical Research, Victoria, Australia
Department of Endocrinology and Metabolism, BSMMU, Dhaka, Bangladesh
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Jun Yang
Jun Yang
Department of Medicine, Monash University, Melbourne, Victoria, Australia
Centre for Endocrinology and Metabolism, Hudson Institute of Medical Research, Victoria, Australia
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Centre for Endocrinology and Metabolism, Hudson Institute of Medical Research, Victoria, Australia
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Jinbo Hu
Jinbo Hu
Department of Endocrinology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China
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Qifu Li
Qifu Li
Department of Endocrinology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China
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Peter J Fuller
Peter J Fuller
Centre for Endocrinology and Metabolism, Hudson Institute of Medical Research, Victoria, Australia
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.3109/02813432.2011.554015 ) 2 Douma S Petidis K Doumas M Papaefthimiou P Triantafyllou A Kartali N Papadopoulos N Vogiatzis K & Zamboulis C . Prevalence of primary hyperaldosteronism in resistant hypertension: a retrospective observational study . Lancet
Kuang Hung
Kuang Hung
Department of Medical Imaging, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan
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Bo-Ching Lee
Bo-Ching Lee
Department of Medical Imaging, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan
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Po-Ting Chen
Po-Ting Chen
Department of Medical Imaging, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan
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Kao-Lang Liu
Kao-Lang Liu
Department of Medical Imaging, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan
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Chin-Chen Chang
Chin-Chen Chang
Department of Medical Imaging, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan
Department and Graduate Institute of Forensic Medicine, National Taiwan University College of Medicine, Taipei, Taiwan
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Department and Graduate Institute of Forensic Medicine, National Taiwan University College of Medicine, Taipei, Taiwan
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Vin-Cent Wu
Vin-Cent Wu
Department of Internal Medicine, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan
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Yen-Hung Lin
Yen-Hung Lin
Department of Internal Medicine, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan
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BS Auchus R Holt S Watumull L Dolmatch B Nesbitt S Vongpatanasin W Victor R Wians F , Primary hyperaldosteronism: Effect of adrenal vein sampling on surgical outcome . Archives of Surgery 2006 141 497 – 502 . ( https://doi.org/10
