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Laura J Reid Edinburgh Centre for Endocrinology and Diabetes, Royal Infirmary of Edinburgh, Edinburgh, UK

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Bala Muthukrishnan Edinburgh Centre for Endocrinology and Diabetes, Royal Infirmary of Edinburgh, Edinburgh, UK

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Dilip Patel Department of Radiology, Royal Infirmary of Edinburgh, Edinburgh, UK

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Mike S Crane Department of Clinical Biochemistry, Royal Infirmary of Edinburgh, Edinburgh, UK

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Murat Akyol Department of Surgery, Royal Infirmary of Edinburgh, Edinburgh, UK

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Andrew Thomson Department of Pathology, Royal Infirmary of Edinburgh, Edinburgh, UK

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Jonathan R Seckl Edinburgh Centre for Endocrinology and Diabetes, Royal Infirmary of Edinburgh, Edinburgh, UK
Centre for Cardiovascular Science, Queen’s Medical Research Unit, University of Edinburgh, Edinburgh, UK

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Fraser W Gibb Edinburgh Centre for Endocrinology and Diabetes, Royal Infirmary of Edinburgh, Edinburgh, UK

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Introduction Primary hyperparathyroidism (PHPT) is a common endocrine condition with a prevalence of 0.1–1%, a female preponderance and a strong association with ageing ( 1 , 2 ). In the modern era, PHPT is often detected incidentally through

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-18-0195
Volume/Issue:
Volume 7: Issue 10
Open access
Anne M Drewes University of Aarhus, Aarhus C, Denmark

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Maria E Møller The Danish Cancer Society, Denmark (Kræftens Bekæmpelse), København Ø, Denmark

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Rasmus Hertzum-Larsen The Danish Cancer Society, Denmark (Kræftens Bekæmpelse), København Ø, Denmark

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Gerda Engholm The Danish Cancer Society, Denmark (Kræftens Bekæmpelse), København Ø, Denmark

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Hans H Storm The Danish Cancer Society, Denmark (Kræftens Bekæmpelse), København Ø, Denmark

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. An analysis from United States Surveillance, Epidemiology, and End Results Program (SEER) on data from 1993–2000 showed that women diagnosed with breast cancer before the age of 40 had an increased risk of a new primary brain tumour (O/E: 1.80 ( Table

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-19-0498
Volume/Issue:
Volume 9: Issue 1
Open access
Lu Yang Department of Nuclear Medicine, the First Affiliated Hospital of Chongqing Medical University, Chongqing, China

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Xingguo Jing Department of Nuclear Medicine, the First Affiliated Hospital of Chongqing Medical University, Chongqing, China

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Hua Pang Department of Nuclear Medicine, the First Affiliated Hospital of Chongqing Medical University, Chongqing, China

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Lili Guan Department of Nuclear Medicine, the First Affiliated Hospital of Chongqing Medical University, Chongqing, China

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Mengdan Li Department of Nuclear Medicine, the First Affiliated Hospital of Chongqing Medical University, Chongqing, China

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Introduction Primary hyperparathyroidism (PHPT) was originally identified approximately 90 years ago ( 1 ). It is the third-most prevalent endocrine illness and the most common cause of hypercalcemia in patients. The vast majority of cases are

Article Type:
Review Article
Collections:
Bone and Mineral Metabolism
DOI:
https://doi.org/10.1530/EC-23-0492
Volume/Issue:
Volume 13: Issue 5
Open access
Luchuan Li Department of Thyroid Surgery, General Surgery, Qilu Hospital of Shandong University, Jinan, Shandong, China

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Baoyuan Li Department of Thyroid Surgery, The Affiliated Yantai Yuhuangding Hospital of Qingdao University, Yantai, Shandong, China

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Bin Lv Department of Thyroid Surgery, General Surgery, Qilu Hospital of Shandong University, Jinan, Shandong, China

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Weili Liang Department of Thyroid Surgery, General Surgery, Qilu Hospital of Shandong University, Jinan, Shandong, China

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Binbin Zhang Department of Thyroid Surgery, General Surgery, Qilu Hospital of Shandong University, Jinan, Shandong, China

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Qingdong Zeng Department of Thyroid Surgery, General Surgery, Qilu Hospital of Shandong University, Jinan, Shandong, China

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Andrew G Turner Clinical and Health Sciences, University of South Australia, Adelaide, South Australia, Australia

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Lei Sheng Department of Thyroid Surgery, General Surgery, Qilu Hospital of Shandong University, Jinan, Shandong, China

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Introduction Primary hyperparathyroidism (PHPT) is a common endocrine disorder, having a prevalence of 0.04–0.1% in the general population ( 1 ). The principal role of parathyroid hormone (PTH) is to maintain (raise) blood calcium levels in

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-21-0217
Volume/Issue:
Volume 10: Issue 8
Open access
Wafaa M Rashed Research Department, Children’s Cancer Hospital Egypt (CCHE-57357), Cairo, Egypt
Armed Forces College of Medicine, Cairo, Egypt

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Anas Saad Faculty of Medicine, Damascus University, Damascus, Syria

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Muneer Al-Husseini Faculty of Medicine, Ain Shams University, Cairo, Egypt

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Ahmed Mahmoud Galal Armed Forces College of Medicine, Cairo, Egypt

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Assem Mohamed Ismael Armed Forces College of Medicine, Cairo, Egypt

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Ahmed M Al-Tayep Armed Forces College of Medicine, Cairo, Egypt

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Ayman El Shafie Armed Forces College of Medicine, Cairo, Egypt

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Mahmoud Ahmed Ali Armed Forces College of Medicine, Cairo, Egypt

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Ahmad Samir Alfaar Charité – Universitätsmedizin Berlin, Campus Virchow Klinikum, Ophthalmology Department, Berlin, Germany

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Introduction The adrenal gland malignancies are extremely sporadic and heterogeneous. It represents 3.6% of endocrine glands cancers ( 1 ). Adrenal malignancies can be either primary adrenal tumors or secondary metastases, with metastases

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-18-0304
Volume/Issue:
Volume 7: Issue 10
Open access
Victor Jing-Wei Kang Departments of Medical Imaging, National Taiwan University Hospital, Taipei, Taiwan

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Bo-Ching Lee Departments of Medical Imaging, National Taiwan University Hospital, Taipei, Taiwan

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Jia-Zheng Huang Departments of Medical Imaging, National Taiwan University Hospital, Taipei, Taiwan

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Vin-Cent Wu Departments of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan

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Yen-Hung Lin Departments of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan

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Chin-Chen Chang Departments of Medical Imaging, National Taiwan University Hospital, Taipei, Taiwan

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TAIPAI group
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Introduction Primary aldosteronism (PA) is the most common cause of secondary hypertension; approximately 5–10% of hypertensive patients may have PA ( 1 ). However, the incidence of PA may be as high as 20% in patients with treatment

Article Type:
Research Article
Collections:
Adrenal
DOI:
https://doi.org/10.1530/EC-23-0056
Volume/Issue:
Volume 12: Issue 9
Open access
Cheng Han Ng Yong Loo Lin School of Medicine, National University of Singapore, Singapore

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Yip Han Chin Yong Loo Lin School of Medicine, National University of Singapore, Singapore

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Marcus Hon Qin Tan Yong Loo Lin School of Medicine, National University of Singapore, Singapore

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Jun Xuan Ng Yong Loo Lin School of Medicine, National University of Singapore, Singapore

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Samantha Peiling Yang Yong Loo Lin School of Medicine, National University of Singapore, Singapore
Department of Medicine, National University Hospital, Singapore

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Jolene Jiayu Kiew Department of Medicine, National University Hospital, Singapore

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Chin Meng Khoo Yong Loo Lin School of Medicine, National University of Singapore, Singapore
Department of Medicine, National University Hospital, Singapore

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Introduction Primary hyperparathyroidism (PHPT) is a common endocrine disorder that is caused by excessive or inappropriate parathyroid hormone (PTH) secretion with simultaneous derangement of both phosphate and calcium metabolism. PHPT is

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-20-0221
Volume/Issue:
Volume 9: Issue 7
Open access
Selina Mäkinen Minerva Foundation Institute for Medical Research, Helsinki, Finland
Department of Medicine, University of Helsinki, Helsinki University Central Hospital, Helsinki, Finland

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Neeta Datta Minerva Foundation Institute for Medical Research, Helsinki, Finland
Department of Medicine, University of Helsinki, Helsinki University Central Hospital, Helsinki, Finland

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Yen H Nguyen Minerva Foundation Institute for Medical Research, Helsinki, Finland
Department of Medicine, University of Helsinki, Helsinki University Central Hospital, Helsinki, Finland

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Petro Kyrylenko Minerva Foundation Institute for Medical Research, Helsinki, Finland
Department of Medicine, University of Helsinki, Helsinki University Central Hospital, Helsinki, Finland

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Markku Laakso Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland, Kuopio, Finland

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Heikki A Koistinen Minerva Foundation Institute for Medical Research, Helsinki, Finland
Department of Medicine, University of Helsinki, Helsinki University Central Hospital, Helsinki, Finland

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Introduction HMG-CoA reductase inhibitors, statins, lower cholesterol levels by inhibiting mevalonate formation, the rate-limiting step in the cholesterol biosynthesis ( 1 ). These drugs are widely used and effective in primary ( 2 , 3 ) and

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-20-0444
Volume/Issue:
Volume 9: Issue 11
Open access
Marieke Stientje Velema Department of Internal Medicine, Radboud University Medical Center, Nijmegen, the Netherlands

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Aline de Nooijer Department of Internal Medicine, Radboud University Medical Center, Nijmegen, the Netherlands

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Ad R M M Hermus Department of Internal Medicine, Radboud University Medical Center, Nijmegen, the Netherlands

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Henri J L M Timmers Department of Internal Medicine, Radboud University Medical Center, Nijmegen, the Netherlands

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Jacques W M Lenders Department of Internal Medicine, Radboud University Medical Center, Nijmegen, the Netherlands
Department of Internal Medicine III, University Hospital Carl Gustav Carus at the Technical University Dresden, Dresden, Germany

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Olga Husson Division of Clinical Studies, Institute of Cancer Research, London, UK

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Jaap Deinum Department of Internal Medicine, Radboud University Medical Center, Nijmegen, the Netherlands
Department of Internal Medicine III, University Hospital Carl Gustav Carus at the Technical University Dresden, Dresden, Germany

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Introduction Primary aldosteronism (PA) is a common cause of hypertension, accounting for 5–15% of hypertensive patients ( 1 , 2 , 3 ). PA is categorized in an aldosterone-producing adenoma (APA) or bilateral adrenal hyperplasia (BAH). When

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-19-0026
Volume/Issue:
Volume 8: Issue 4
Open access
Natacha Driessens Université libre de Bruxelles (ULB), Hôpital Universitaire de Bruxelles (HUB), CUB Hôpital Erasme, Department of Endocrinology, Route de Lennik, Brussels, Belgium

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Madhu Prasai Université libre de Bruxelles (ULB), Hôpital Universitaire de Bruxelles (HUB), CUB Hôpital Erasme, Department of Endocrinology, Route de Lennik, Brussels, Belgium

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Orsalia Alexopoulou Department of Endocrinology, Cliniques Universitaires Saint Luc, Brussels, Belgium

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Christophe De Block Department of Endocrinology-Diabetology-Metabolism, Universitair Ziekenhuis Antwerpen & University of Antwerp, Drie Eikenstraat, Edegem, Belgium

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Eva Van Caenegem Department of Endocrinology, Academisch Ziekenhuis Sint-Jan Brugge – Oostende AV, Ruddershove, Brugge, Belgium

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Guy T’Sjoen Department of Endocrinology, Ghent Universitary Hospital, C. Heymanslaan, Gent, Belgium

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Frank Nobels Department of Endocrinology, Onze-Lieve Vrouw Ziekenhuis, Moorselbaan, Aalst, Belgium

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Christophe Ghys Department of Endocrinology, Universitair Ziekenhuis Brussel, Laarbeeklaan, Brussels, Belgium

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Laurent Vroonen Department of Endocrinology, Cliniques Universitaires de Liège, Avenue de l’hôpital, Liège, Belgium

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Corinne Jonas Department of Endocrinology, CHU UCL Namur - Godinne, Avenue Docteur Gaston Thérasse, Yvoir, Belgium

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Bernard Corvilain Université libre de Bruxelles (ULB), Hôpital Universitaire de Bruxelles (HUB), CUB Hôpital Erasme, Department of Endocrinology, Route de Lennik, Brussels, Belgium

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Dominique Maiter Department of Endocrinology, Cliniques Universitaires Saint Luc, Brussels, Belgium

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Introduction Primary adrenal insufficiency (PAI) is a rare disease, most commonly of auto-immune origin. There is a global variation in prevalence from 80 to 145 per million in Europe, with the highest case numbers reported in Scandinavian

Article Type:
Research Article
Collections:
Adrenal
DOI:
https://doi.org/10.1530/EC-23-0044
Volume/Issue:
Volume 12: Issue 6
Open access